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Maneuvering Angle Rigid Formations With Global Convergence Guarantees

IEEE/CAA Journal of Automatica Sinica 2022年第8期9卷 1464-1475页

作者： Liangming Chen Zhiyun Lin hector garcia de marina Zhiyong Sun Mir Feroskhan School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore department of Computer Architecture and Technology and also with CITICUniversity of Granada18014 GranadaSpain department of Electrical Engineering Eindhoven University of Technology5600 MB Eindhoventhe Netherlands

Angle rigid multi-agent formations can simultaneously undergo translational,rotational,and scaling maneuvering,therefore combining the maneuvering capabilities of both distance and bearing rigid ***,maneuvering angle rigid formations in 2D or 3D with global convergence guarantees is shown to be a challenging problem in the existing literature even when relative position measurements are *** by angle-induced linear equations in 2D triangles and 3D tetrahedra,this paper aims to solve this challenging problem in both 2D and3D under a leader-follower *** the 2D case where the leaders have constant velocities,by using local relative position and velocity measurements,a formation maneuvering law is designed for the followers governed by double-integrator *** the leaders have time-varying velocities,a sliding mode formation maneuvering law is proposed by using the same *** the 3D case,to establish an angle-induced linear equation for each tetrahedron,we assume that all the followers'coordinate frames share a common Z ***,a formation maneuvering law is proposed for the followers to globally maneuver Z-weakly angle rigid formations in *** extension to Lagrangian agent dynamics and the construction of the desired rigid formations by using the minimum number of angle constraints are also *** examples are provided to validate the effectiveness of the proposed algorithms.

关键词： Index Terms—Angle rigid formations formation control formation maneuvering global convergence multi-agent systems

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Molecular aspects of mammalian fertilization

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Asian Journal of Andrology 2001年第4期3卷 243-249页

作者： hector Serrano Dolores garcia-Suarez dept. Health Sciences Dept. Biology Universidad Autonoma Metropoliana-Iztapalapa Ave. Michoacan and Purisima Mexico City DF 09340 Mexico

Mammalian fertilization is a highly regulated process, much of which are not clearly understood. Here we presentsome information in order to elaborate a working hypothesis for this process, beginning with the sperm modifications inthe epidydimis up to sperm and egg plasmalemma interaction and fusion. We also discuss the still poorly understood ca-pacitation process, the phenomenon of sperm chemo-attraction that brings the capacitated sperm to interact with theoocyte vestments and certain aspects of the acrosome reaction. (Asian J Androl 2001 dec; 3 : 243 - 249)

关键词： fertilization sperm maturation sperm capacitation sperm-ovum interactions membrane fusion

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Recurrent anal fistulae:Limited surgery supported by stem cells

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World Journal of Gastroenterology 2015年第11期21卷 3330-3336页

作者： Damian garcia-Olmo hector Guadalajara Ines Rubio-Perez Maria Dolores Herreros Paloma de-la-Quintana Mariano garcia-Arranz Hospital Fundación Jimenez Díaz Colorectal Surgery Unit University Hospital Fundación Jiménez Díaz Colorectal Surgery Unit La Paz University Hospital Cell Therapy Laboratory University Hospital Fundación Jiménez Díaz

AIM:To study the results of stem-cell therapy under a Compassionate-use Program for patients with recurrent anal ***:Under controlled circumstances,and approved by European and Spanish laws,a Compassionate-use Program allows the use of stem-cell therapy for patients with very complex anal *** had previously undergone multiple surgical interventions that had failed to resolve the fistulae,and presented symptomatic *** intervention consisted of limited surgery(with closure of the internal opening),followed by local implant of stem cells in the fistula-tract *** expanded adipose-derived stem cells were the main cell type selected for *** first evaluation was performed on the 8th postoperative week;outcome was classified as response or partial *** one year after the intervention confirmed if complete healing of the fistula was ***:Ten patients(8 male)with highly recurrent and complex fistulae were treated(mean age:49years,range:28-76 years).Seven cases were nonCrohn’s fistulae,and three were Crohn’s-associated *** surgical attempts ranged from 3to *** patients presented with preoperative incontinence(Wexner scores of 12 and 13 points).After the intervention,six patients showed clinical response on the 8th postoperative week,with a complete cessation of suppuration from the *** patients presented a partial response,with an evident decrease in suppuration.A year later,six patients(60%)remained healed,with complete reepithelization of the external *** Wexner Scores were 0 in six *** two patients with previous incontinence improved their scores from12 to 8 points and from 13 to 5 *** adverse reactions or complications related to stem-cell therapy were reported during the study ***:Stem cells are safe and useful for treating anal *** can be achieved in severe cases,sparing fecal incontinence risk,and impr

关键词： Adipose-derived stem cells Cell therapy Compassion

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Geodesic Vulnerability Approach for Identification of Critical Buses in Power Systems

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Journal of Modern Power Systems and Clean Energy 2021年第1期9卷 37-45页

作者： Jesus Beyza Eduardo garcia-Paricio hector F.Ruiz Jose M.Yusta Instituto Tecnologico de Morelia Avenida Tecnologico 1500Lomas de Santiaguito58120Mexico the department of Electrical Engineering University of ZaragozaC/Maria de Luna 350018Spain

One of the most critical issues in the evaluation of power systems is the identification of critical buses. For this purpose, this paper proposes a new methodology that evaluates the substitution of the power flow technique by the geodesic vulnerability index to identify critical nodes in power *** methods are applied comparatively to demonstrate the scope of the proposed approach. The applicability of the methodology is illustrated using the IEEE 118-bus test system as a case study. To identify the critical components, a node is initially disconnected, and the performance of the resulting topology is evaluated in the face of simulations for multiple cascading faults. Cascading events are simulated by randomly removing assets on a system that continually changes its structure with the elimination of each component. Thus, the classification of the critical nodes is determined by evaluating the resulting performance of 118 different topologies and calculating the damaged area for each of the disintegration curves of cascading failures. In summary, the feasibility and suitability of complex network theory are justified to identify critical nodes in power systems.

关键词： Power system critical node complex network theory cascading failure load flow

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Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist

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World Journal of Gastroenterology 2017年第31期23卷 5755-5763页

作者： Yung Ka Chin Julio Iglesias-garcia Daniel de la Iglesia Jose Larino-Noia Ihab Abdulkader-Nallib hector Lázare Susana Rebolledo Olmedo J Enrique Dominguez-Munoz department of Gastroenterology and Hepatology University Hospital of Santiago de Compostela Health Research Institute of Santiago de Compostela (IDIS) University Hospital of Santiago de Compostela department of Pathology University Hospital of Santiago de Compostela

To evaluate factors that influence the diagnostic accuracy of endoscopic ultrasound (EUS)-guided tissue acquisition for lymph node enlargement in the absence of an on-site pathologist. METHODSA retrospective analysis of patients who underwent EUS-guided tissue acquisition for the pathological diagnosis of lymph node enlargement between April 2012 and June 2015 is reported. Tissue acquisition was performed with both cytology and biopsy needles of different calibers. The variables evaluated were lymph node location and size, number of passes and type of needle used. Final diagnosis was based on surgical histopathology or, in non-operated cases, on EUS-guided tissue acquisition and imaging assessment with a minimum clinical follow-up of 6 mo. RESULTSDuring the study period, 168 lymph nodes with a median size of 20.3 mm (range 12.5-27) were sampled from 152 patients. Ninety lymph nodes (53.6%) were located at mediastinum, and 105 (62.5%) were acquired with biopsy needles. The final diagnosis was benign/reactive origin in 87 cases (51.8%), malignant in 65 cases (38.7%), and lymphoma in 16 cases (9.5%). The sensitivity, specificity, positive predictive value and negative predictive value for the detection of malignancy were 74.1%, 100%, 100% and 80.6%, respectively. The overall accuracy was 87.5% (95%CI: 81.7-91.7). No variables were independently associated with a correct final diagnosis according to the multivariate analysis. CONCLUSIONEUS-guided tissue acquisition is a highly accurate technique for assessing lymph node enlargement. None of the variables evaluated were associated with diagnostic accuracy.

关键词： Lymph node Endoscopic ultrasound Fine-needle aspiration Fine-needle biopsy Accuracy

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Examination of the profitability of technical analysis based on moving average strategies in BRICS

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Financial Innovation 2018年第1期4卷 44-61页

作者： Matheus JoséSilva de Souza Danilo Guimarães Franco Ramos marina garcia Pena Vinicius Amorim Sobreiro Herbert Kimura department of Economics University of BrasíliaFederal DistrictBrazil department of Management University of BrasíliaFederal DistrictBrazil.

In this paper,we investigated the profitability of technical analysis as applied to the stock markets of the BRICS member *** addition,we searched for evidence that technical analysis and fundamental analysis can complement each other in these *** implement this research,we created a comprehensive portfolio containing the assets traded in the markets of each BRICS *** developed an automated trading system that simulated transactions in this portfolio using technical analysis *** assessment updated the findings of previous research by including more recent data and adding South Africa,the latest member included in *** results showed that the returns obtained by the automated system,on average,exceeded the value *** were groups of assets from each country that performed well above the portfolio average,surpassing the returns obtained using a buy and hold *** returns from the sample portfolio were very strong in Russia and *** also found that technical analysis can help fundamental analysis identify the most dynamic companies in the stock market.

关键词： Technical analysis Moving average strategies Automated trading systems Portfolio analysis BRICS

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Modelling extraordinary floods and sedimentological processes in a large channel-floodplain system of the Lower Paran River(Argentina)

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International Journal of Sediment Research 2015年第2期30卷 150-159页

作者： marina L.garcia Pedro A.Basile Gerardo A.Riccardi José F.Rodriguez Hydraulics department School of Civil EngineeringFaculty of Exact SciencesEngineering and Land SurveyingNational University of Rosario Centre for Hydro-Environmental Research Faculty of Exact SciencesEngineering and Land SurveyingNational University of Rosario Research Council of National University of Rosario(CIUNR) Civil Surveying and Environmental EngineeringUniversity of Newcastle

A quasi-2D unsteady flow and sediment transport model suitable for the simulation of large lowland river systems,including their floodplains,is *** water flow and sediment equations are discretised using an interconnected irregular cells scheme,in which different simplifications of the 1D de Saint Venant equations are used to define the discharge laws between ***-distributed transport and deposition of fine sediments throughout the river-floodplain system are *** model is applied over a 208-km reach of the Parana River between the cities of Diamante and Ramallo（Argentina） comprising a river-floodplain area of 8100 km;.After calibration and validation,the model is applied to predict water and sediment dynamics during synthetically generated extraordinary floods of100,1000,and 10,000 years return *** potential impact of a 56-km long road embankment constructed across the entire floodplain is simulated and compared to model results without the *** embankment results in increases in upstream water levels,inundation extent,flow duration,and sediment deposition.

关键词： Fluvial hydraulics Numerical modelling Floodplain sedimentation Lowland rivers Parana River

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Suppression of hepatic steatosis in non-alcoholic steatohepatitis model by modified Xiaoyao San formula:Evidence,mechanisms and perspective

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World Journal of Hepatology 2024年第10期16卷 1208-1212页

作者： Nabil Eid Payal Bhatnagar Li-Li Chan marina garcia-Macia department of Anatomy Division of Human BiologySchool of MedicineIMU UniversityKuala Lumpur 57000Malaysia department of Pharmaceutical Technology School of pharmacyIMU UniversityKuala Lumpur 57000Malaysia department of Pathology and Pharmacology School of MedicineIMU UniversityKuala Lumpur 57000Malaysia Institute of Functional Biology and Genomics Department of Biochemistry and Molecular BiologyUniversity of SalamancaSalamanca 37007Spain

In this letter,we comment on a recent publication by Mei et al,in the World Journal of Hepatology,investigating the hepatoprotective effects of the modified Xiaoyao San(MXS)formula in a male rat model of non-alcoholic steatohepatitis(NASH).The authors found that MXS treatment mitigated hepatic steatosis and inflam-mation in the NASH model,as evidenced by the reduction in lipid droplets(LDs),fibrosis markers and lipogenic ***,these hepatoprotective effects were associated with androgen upregulation(based on metabolomics analysis of male steroid hormone metabolites),adenosine 5’-monophosphate-activated protein kinase(AMPK)activation,and restoration of phosphatase and tensin homolog(PTEN)***,the authors did not clearly discuss the relationships between MXS-induced hepatic steatosis reduction in the NASH model,and androgen upregulation,AMPK activation,and restoration of PTEN *** editorial emphasizes the reported mechanisms and explains how they act or interact with each other to reduce hepatic steatosis and inflammation in the NASH *** a perspective,we propose additional mechanisms(such as autophagy/lipophagy activation in hepatocytes)for the clearance of LDs and suppression of hepatic steatosis by MXS in the NASH model.A proper understanding of the mechanisms of MXS-induced reduction of hepatic steatosis might help in the treatment of NASH and related diseases.

关键词： Steatosis Liver Xiaoyao San Inflammation Androgen Adenosine 5’-monophosphate-activated protein kinase Phosphatase and tensin homolog Autophagy Lipophagy Alpha smooth muscle actin

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An in vivo approach to the reported effects of phenolic acids and flavonoids on the pancreaticα-amylase activity

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Food Bioscience 2023年第1期51卷 1229-1236页

作者： Barbara Ribeiro Tonsic Vanesa Gesser Correa Jessica Amanda Andrade garcia-Manieri Adelar Bracht Rosane marina Peralta Programa de Pos-graduaçao em Ciencia de Alimentos Brazil Programa de Pos-graduaçao em Bioquímica Universidade Estadual de MaringaBrazil

Reduction in the activity of theα-amylases which hydrolyze starch and glycogen has been proposed for diminishing the incidence of obesity and *** plant extracts contain inhibitors ofα-amylases andα-glucosidases and several molecules with this activity have been *** present work attempts at investigating if several natural compounds(flavonoids and phenolic acids)that have been reported to be inhibitors of those hydrolytic enzymes can also inhibit starch absorption in *** starch tolerance test in mice was used for assaying starch absorption after administration of 100 mg/kg of five flavonoids(epicatechin,catechin,rutin,quercetin,naringenin)and five phenolic acids(gallic,syringic,vanillic,sinapic,ferulic),which are known in vitro inhibitors ofα-*** the flavonoids,only rutin inhibited starch absorption in mice,even though its effect was only 33%of that one found for the positive control *** the five phenolic acids tested only syringic acid produced a clear diminution in starch absorption,which was 47%of that one found with *** the other hand,other three phenolic acids,namely gallic,sinapic and ferulic acid,caused delay in the absorption of starch,which was characterized by a shift in the time peak of maximal blood glucose concentration,with no modification in the excess of glucose that effectively entered the *** at detecting eventual synergisms by administrating mixtures of flavonoids and phenolic acids were *** results recommend careful translation of in vitro data on the inhibition ofα-amylases andα-glucosidases to the in vivo conditions.

关键词： α-amylase Inhibition Flavonoids Phenolic acids Starch Absorption

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Intragastric injection of botulinum toxin for the treatment of obesity. Where are we?

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World Journal of Gastroenterology 2008年第12期14卷 1805-1809页

作者： Diego garcia-Compean hector Maldonado Garza department of Gastroenterology Faculty of Medicine University Hospital. Ave Madero y Gonzalitos Col Mitras Centro Monterrey 64700 Mexico

Obesity has reached epidemic proportions particularly in western countries. Most non-surgical treatments of this condition are disappointing. Since 2005, several studies evaluating the effect of Botulinum Toxin type A (BT-A) in gastric antrum by means of endoscopy for the treatment of obesity have been published. This treatment modality was based on the observation that gastric injection of BT-A in laparatomized rats induced a significant reduction of food intake and body weight. Nowadays, 6 studies have been published yielding conflicting results. Differences in selection of patients, doses of BT-A, method of administration of the toxin and instruments of evaluation of some parameters among these studies may be the cause of divergent results. We discuss herein some important features of these studies pointing out on differences among them. At the same time, based on the knowledge of physiological characteristics of normal and abnormal gastric function related with feeding, we discuss the probable causes of failure observed in these trials. Finally, we give some guidelines concerning the way that future research in this field may follow, not without calling attention to disadvantages of this treatment.

关键词： Botulinum toxin Obesity Gastric emptying Gastric motility Gastroparesis

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