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Impact of auditory stimulation nursing protocol on auditory response in cerebrovascular stroke patients

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Journal of Integrative Nursing 2024年第2期6卷 111-116页

作者： mohammed ElSayed ZAKY Hanan Ahmed AL SEBAEE Nagat El Morsy IBRAHIEM heba Ahmed mohammed Mohammad Edrees MOHAMMAD Department of Medical Surgical Nursing Faculty of NursingCairo UniversityCairoEgypt Department of Neurology Faculty of MedicineCairo UniversityCairoEgypt

Objectives:The objective of the study was to explore the impact of auditory stimulation protocol on auditory response in cerebrovascular stroke(CVS)*** and Methods:A pre-posttest nonequivalent control group quasi-experimental study was conducted at Al Mainal Hospital at Al Kars Einy Hospital,Cairo University,among 60 CVS patients,and the sample was randomly assigned through a coin to allocate subjects to study or control group(30 for each group).Auditory stimulation techniques were applied three times per week for the study group for two consecutive *** in the control group received only routine hospital care during the study *** Glasgow Coma Scale(GCS)score for assessing the neurological function and level of arousal and the auditory subscale score of Western Neuro Sensory Stimulation Profile(WNSSP)for assessing auditory response were recorded and compared between the two groups before and after the ***:There were statistically significant differences between the study group and the control group regarding third reading of GCS score(11.5±0.3 vs.10.6±0.9,t=4.676,P=0.000).The scores of all auditory subscales of WNSSP in the study groups increased after implementing the auditory stimulation protocol(P<0.05).Conclusion:Utilizing the auditory stimulation protocol by nurse proves to be an effective method for enhancing hearing responses in individuals with CVS.

关键词： Auditory stimulation techniques hearing response nursing management stroke

Adherence to Advisory Committee on Immunization Practices in diabetes mellitus patients in Saudi Arabia:A multicenter retrospective study

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World Journal of Diabetes 2024年第3期15卷 440-454页

作者： Saleh Fahad Alqifari Aya K Esmail Dalal M Alarifi Ghalya Y Alsuliman Maram M Alhati May R Mutlaq mohammed Aldhaeefi Shaden A Alshuaibi Palanisamy Amirthalingam Abrar abdallah Afaf S Wasel heba R Hamad Shoroq Alamin Tasneem H Atia Tariq Alqahtani Department of Pharmacy Practice University of TabukTabuk 71491Saudi Arabia Department of Clinical Sciences Sulaiman Alrajhi UniversityQassim 52726Saudi Arabia Department of Family Medicine International Medical CenterJeddah 23214Saudi Arabia Clinical and Administrative Pharmacy Sciences College of PharmacyHoward UniversityWashingtonDC 20059United States Department of Pharmacology King Saud Bin Abdulaziz University for Health SciencesKing Abdullah International Medical Research CenterRiyadh 11481Saudi Arabia

BACKGROUND Patients with diabetes mellitus(DM)are predisposed to an increased risk of infection signifying the importance of vaccination to protect against its potentially severe *** Centers for Disease Control and Prevention/Advisory Committee on Immunization Practices(CDC/ACIP)issued immunization recommendations to protect this patient *** To assess the adherence of patients with DM to the CDC/ACIP immunization recommendations in Saudi Arabia and to identify the factors associated with the vaccine adherence *** An observational retrospective study conducted in 2023 was used to collect data on the vaccination records from 13 diabetes care centers in Saudi Arabia with 1000 eligible patients in phase I with data collected through chart review and 709 patients in phase II through online *** Among participants,10.01%(n=71)had never received any vaccine,while 85.89%(n=609)received at least one dose of the coronavirus disease 2019(COVID-19)vaccine,and 34.83%(n=247)had received the annual influenza *** 2.96%(n=21),2.11%(n=15),and 1.12%(n=8)received herpes zoster,tetanus,diphtheria,and pertussis(Tdap),and human papillomavirus(HPV)vaccines,*** patients with DM in Saudi Arabia,the rate of vaccination for annual influenza and COVID-19 vaccines was higher compared to other vaccinations such as herpes zoster,Tdap,pneumococcal,and *** such as vaccine recommendations provided by family physicians or specialists,site of care,income level,DM-related hospitalization history,residency site,hemoglobin A1c(HbA1c)level,and health sector type can significantly influence the vaccination rate in patients with *** non-vaccinated patients with DM,the most reported barriers were lack of knowledge and fear of side *** signifies the need for large-scale research in this area to identify additional factors that might facilitate adherence to CDC/ACIP vaccine recommendations in patients with *** In S

关键词： Diabetes mellitus Vaccine recommendation COVID-19 vaccine Influenza vaccine Pneumococcal vaccine Immunization Retrospective study

Reliability Analysis of HEE Parameters via Progressive Type-II Censoring with Applications

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2761-2793页

作者： heba S.mohammed Mazen Nassar Refah Alotaibi Ahmed Elshahhat Department of Mathematical Sciences College of SciencePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Statistics Faculty of ScienceKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Statistics Faculty of CommerceZagazig UniversityZagazigEgypt Faculty of Technology and Development Zagazig UniversityZagazig44519Egypt

A new extended exponential lifetime model called Harris extended-exponential(HEE)distribution for data modelling with increasing and decreasing hazard rate shapes has been *** the reliability context,researchers prefer to use censoring plans to collect data in order to achieve a compromise between total test time and/or test sample ***,this study considers both maximum likelihood and Bayesian estimates of the Harris extended-exponential distribution parameters and some of its reliability indices using a progressive Type-II censoring *** the premise of independent gamma priors,the Bayesian estimation is created using the squared-error and general entropy loss *** to the challenging form of the joint posterior distribution,to evaluate the Bayes estimates,samples from the full conditional distributions are generated using Markov Chain Monte Carlo *** each unknown parameter,the highest posterior density credible intervals and asymptotic confidence intervals are also *** a simulated study,the usefulness of the various suggested strategies is *** optimal progressive censoring plans are also shown,and various optimality criteria are *** actual data sets,taken from engineering and veterinary medicine areas,are analyzed to show how the offered point and interval estimators can be used in practice and to verify that the proposed model furnishes a good fit than other lifetimemodels:alpha power exponential,generalized-exponential,Nadarajah-Haghighi,Weibull,Lomax,gamma and exponential *** evaluations revealed that in the presence of progressively Type-II censored data,the Bayes estimation method against the squared-error(symmetric)loss is advised for getting the point and interval estimates of the HEE distribution.

关键词： Harris extended-exponential model progressive Type-II censoring reliability maximum likelihood MCMC techniques Monte Carlo experiments

Association of anxiety- depressive disorders with irritable bowel syndrome among patients attending a rural family practice center: a comparative cross- sectional study

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General Psychiatry 2021年第6期34卷 16-23页

作者： Alaa Adel mohammed heba Ahmed Moustafa hebatallah Nour-Eldein Rabab Atta Saudi Family Medicine Department Suez Canal UniversityIsmailiaEgypt

Background Comorbidity of irritable bowel syndrome(IBS)and psychiatric disorders is common,and the prevalence of at least one psychiatric disorder has been reported as high as 80%among patients with *** To explore the association of anxiety-depressive disorders with IBS and its different subtypes,and to evaluate the associations of lifestyle habits,dietary habits and sleeping quality with *** A comparative cross-sectional study was conducted at the AL-Mahsama Family Practice Center,Ismailia,*** was carried out between October 2019 and October *** were categorised into 175 patients with IBS,diagnosed using the Rome IV criteria,and 175 patients without IBS.A semistructured questionnaire was used to collect data on sociodemographic characteristics,lifestyle habits,dietary habits and sleep quality from both *** Hamilton Anxiety Rating Scale was used to assess anxiety symptoms,whereas the Beck Depression Inventory Second Edition was used to assess depression *** There was a high statistically significant difference between both groups with regard to age,education,occupation and socioeconomic status(SES),being a smoker,being physically inactive,having sleep disturbance and having irregular meals;being either obese or overweight was more reported in the IBS *** was a high statistically significant difference in the rate of anxiety and depression between patients with and without ***,moderate and severe anxiety were reported in 37.1%,42.9%and 20.0%of patients with IBS while most(80.0%)of the patients without IBS reported mild *** depression,mild,moderate and severe depression were reported in 60.0%,14.3%and 25.7%of the patients with IBS while most(82.9%)of the non-IBS participants reported mild *** The study shows a significant association between anxiety-depressive disorders and IBS,but no significant associations between anxiety-depressive disorders and IBS subtypes.

关键词： patients disorders sectional

Automated Autism Spectral Disorder Classification Using Optimal Machine Learning Model

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Computers, Materials & Continua 2023年第3期74卷 5251-5265页

作者： Hanan Abdullah Mengash Hamed Alqahtani mohammed Maray Mohamed K.Nour Radwa Marzouk mohammed Abdullah Al-Hagery heba Mohsen Mesfer Al Duhayyim Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information Systems College of Computer ScienceCenter of Artificial Intelligence and Unit of CybersecurityKing Khalid UniversityAbhaSaudi Arabia Department of Information Systems College of Computer ScienceKing Khalid UniversityAbhaSaudi Arabia Department of Computer Sciences College of Computing and Information SystemUmm Al-Qura UniversitySaudi Arabia Department of Computer Science College of ComputerQassim UniversitySaudi Arabia Department of Computer Science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt Department of Computer Science College of Sciences and Humanities-AflajPrince Sattam bin Abdulaziz UniversitySaudi Arabia

Autism Spectrum Disorder (ASD) refers to a neuro-disorder wherean individual has long-lasting effects on communication and interaction *** information technologywhich employs artificial intelligence(AI) model has assisted in early identify ASD by using pattern *** advances of AI models assist in the automated identification andclassification of ASD, which helps to reduce the severity of the *** study introduces an automated ASD classification using owl searchalgorithm with machine learning (ASDC-OSAML) model. The proposedASDC-OSAML model majorly focuses on the identification and classificationof ASD. To attain this, the presentedASDC-OSAML model follows minmaxnormalization approach as a pre-processing stage. Next, the owl searchalgorithm (OSA)-based feature selection (OSA-FS) model is used to derivefeature subsets. Then, beetle swarm antenna search (BSAS) algorithm withIterative Dichotomiser 3 (ID3) classification method was implied for ASDdetection and classification. The design of BSAS algorithm helps to determinethe parameter values of the ID3 classifier. The performance analysis of theASDC-OSAML model is performed using benchmark dataset. An extensivecomparison study highlighted the supremacy of the ASDC-OSAML modelover recent state of art approaches.

关键词： Autism spectral disorder machine learning owl search algorithm feature selection id3 classifier

Coati Optimization-Based Energy Efficient Routing Protocol for Unmanned Aerial Vehicle Communication

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Computers, Materials & Continua 2023年第6期75卷 4805-4820页

作者： Hanan Abdullah Mengash Hamed Alqahtani mohammed Maray Mohamed K.Nour Radwa Marzouk mohammed Abdullah Al-Hagery heba Mohsen Mesfer Al Duhayyim Department of Information Systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information Systems College of Computer ScienceCenter of Artificial Intelligence and Unit of CybersecurityKing Khalid UniversityAbha62529Saudi Arabia Department of Information Systems College of Computer ScienceKing Khalid UniversityAbha62529Saudi Arabia Department of Computer Sciences College of Computing and Information SystemsUmm Al-Qura UniversityMecca24382Saudi Arabia Department of Computer Science College of ComputerQassim UniversityBuraydah52571Saudi Arabia Department of Computer Science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt Department of Computer Science College of Sciences and Humanities-AflajPrince Sattam bin Abdulaziz UniversityAl-Kharj16278Saudi Arabia

With the flexible deployment and high mobility of Unmanned Aerial Vehicles(UAVs)in an open environment,they have generated con-siderable attention in military and civil applications intending to enable ubiquitous connectivity and foster agile *** difficulty stems from features other than mobile ad-hoc network(MANET),namely aerial mobility in three-dimensional space and often changing *** the UAV network,a single node serves as a forwarding,transmitting,and receiving node at the same ***,the communication path is multi-hop,and routing significantly affects the network’s performance.A lot of effort should be invested in performance analysis for selecting the optimum routing *** this motivation,this study modelled a new Coati Optimization Algorithm-based Energy-Efficient Routing Process for Unmanned Aerial Vehicle Communication(COAER-UAVC)*** presented COAER-UAVC technique establishes effective routes for communication between the *** is primarily based on the coati characteristics in nature:if attacking and hunting iguanas and escaping from ***,the presented COAER-UAVC technique concentrates on the design of fitness functions to minimize energy utilization and communication delay.A varied group of simulations was performed to depict the optimum performance of the COAER-UAVC *** experimental results verified that the COAER-UAVC technique had assured improved performance over other approaches.

关键词： Artificial intelligence unmanned aerial vehicle data communication routing protocol energy efficiency

Pterostilbene induces cell apoptosis and inhibits lipogenesis in SKOV3 ovarian cancer cells by activation of AMPK-induced inhibition of Akt/mTOR signaling cascade

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BIOCELL 2021年第1期45卷 89-101页

作者： ATTALLA EL-KOTT EMAN ELBEALY FAHMY ELSAID HAITHAM EL-MEKKAWY ABD-EL-KARIM ABD-LATEIF ABDULALI TAWEEL heba KHALIFA AHMAD KANDEEL KAREEM MORSY ESSAM ibrahim MASHAEL mohammed BIN-MEFERIJ Biology Department College of ScienceKing Khalid UniversityAbha61413Saudi Arabia Zoology Department College of ScienceDamanhour UniversityDamanhour22511Egypt Biology Department College of Science for GirlsKing Khalid UniversityAbha61413Saudi Arabia Zoology Department College of ScienceMansoura UniversityMansoura35511Egypt Zoology Department College of ScienceFayoum UniversityFayoum63511Egypt Zoology Department Faculty of ScienceAl-Zawia UniversityAl-ZawiaLibya Biology Department Faculty of ScienceCairo UniversityCairo12611Egypt Research Center for Advanced Materials Science(RCAMS) King Khalid UniversityAbha61413Saudi Arabia Blood Products Quality Control and Research Department National Organization for Research and Control of BiologicalsCairo12611Egypt Biology Department College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadhSaudi Arabia

This study investigates if the anti-tumor effect of Pterostilbene in the SKOV3 ovarian cancer(OC)cell line involves inhibition of cell metabolism and tested in this effect involves modulating AMPK and Akt-induced regulation of ***,SKOV3 cells were cultured in the humidified conditions in DMEM media for 24 h with or without increasing concentration of ***,the cells were incubated with Pterostilbene(IC_(50)=50μM)under similar conditions with or without pre-incubation with Dorsomorphin,an AMPK *** a dose-dependent manner,Pterostilbene inhibited SKOV3 cell survival and increased their lysate levels of lactate dehydrogenase(LDH)and single-stranded DNA(ssDNA).When SKOV3 cells were treated with 50μM Pterostilbene,Pterostilbene significantly suppressed cell migration and invasion,reduced lysate levels of lactic acid and the optical density of Oil Red O staining,and increased lysate glucose *** also increased levels of malondialdehyde(MDA),reactive oxygen species(ROS),and induced intrinsic cell apoptosis by upregulating protein levels of Bax and cleaved caspase-3 and reducing protein levels of ***,Pterostilbene reduced mRNA levels of sterol regulatory element-binding protein 1(SREBP-1),fatty acid synthase(FAS),acetyl CoA carboxylase-1(ACC-1),and AMP-activated protein kinase(AMPK).Furthermore,Pterostilbene increased the protein levels of p-AMPK,p-p53,p-raptor,p-TSC-2,but significantly decreased protein levels of p-Akt,p-TSC-2,p-mTOR,p-S6K1,and *** with Dorsomorphin(CC)abolished all the anti-tumorigenesis effects afforded by Pterostilbene and prevented Pterostilbene-induced phosphorylation of Akt,p53,and *** conclusion,the tumorsuppressive effect of Pterostilbene in SKOV3 cells involves the induction of ROS and inhibition of dysregulation cell metabolism mainly due to AMPK-induced Akt-dependent or independent suppression of mTOR.

关键词： Pterostilbene Ovarian cancer Lipogenesis Apoptosis AMPK

Susceptibility patterns and virulence genotypes of Helicobacter pylori affecting eradication therapy outcomes among Egyptian patients with gastroduodenal diseases

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World Journal of Gastroenterology 2023年第19期29卷 2950-2960页

作者： Ahmed Morad Asaad Gasser El-Azab Eman Abdelsameea Osama Elbahr Ahmed Kamal Mohamed Abdel-Samiee Ahmed Abdelfattah heba abdallah Doha Maher Ahmed El-Refaie Samar Ebrahim Ghanem Shamshul Ansari Samah mohammed Awad Department of Microbiology College of MedicineZagazig UniversityZagazig 44519Egypt Department of Hepatology and Gastroenterology National Liver InstituteMenoufia UniversityShebin El-Kom 32511Egypt Department of Clinical Pathology National Liver InstituteMenoufia UniversityShebin El-Kom 32511Egypt Department of Pathology National Liver InstituteMenoufia UniversityShebin El-Kom 32511Egypt Department of Clinical Biochemistry and Molecular Diagnostics National Liver InstituteMenoufia UniversityShebin El-Kom 32511Egypt Department of Health Sciences Higher Colleges of TechnologyAbu Dhabi Women's CollegeAbu Dhabi 25026United Arab Emirates Department of Clinical Microbiology and Immunology National Liver InstituteMenoufia UniversityShebin El-Kom 32511Egypt

BACKGROUND Helicobacter pylori(***)is a significant human pathogen that is responsible for a variety of illnesses,including mucosa-associated lymphoid tissue lymphoma,gastric cancer,peptic ulcers,and *** To investigate the frequency of *** infection and its resistance patterns among Egyptian patients and to determine the influence of *** virulence genetic determinants on the eradication success of 14-d triple therapy *** *** infections were investigated in 72 patients with gastroduodenal complications suggestive of *** *** cagA and vacA genotypes of cultured strains were studied using polymerase chain *** patients underwent 14 d of triple-therapy *** treatment response was examined using histology and a rapid urease test 6 wk after therapy *** The intention-to-treat eradication rate was 59.2%(95%CI:48.2%-70.3%).Rates of *** resistance to clarithromycin,amoxicillin,and metronidazole were 52.8%,81.9%,and 100%,*** eradication of *** was more significantly associated with vacA s1-positive strains[adjusted odds ratio(aOR)=0.507,95%CI:0.175-0.822].A significant association was found between failed eradication rate and *** strains resistant to clarithromycin(aOR=0.204,95%CI:-0.005 to 0.412)and amoxicillin(aOR=0.223,95%CI:0.026-0.537).CONCLUSION This study’s low *** eradication rate following 14-d triple therapy is concerning and *** pan-resistance to metronidazole followed by the high resistance to ciprofloxacin,amoxicillin,and clarithromycin in this research is challenging and of great concern.

关键词： Helicobacter pylori Eradication therapy Virulence Clarithromycin resistance cagA gene vacA gene

Effects of adherence to the Mediterranean diet in children and adolescents with irritable bowel syndrome

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World Journal of Clinical Pediatrics 2022年第4期11卷 330-340页

作者： mohammed Al-Biltagi Doaa El Amrousy heba El Ashry Sara Maher Mahmoud A mohammed Samir Hasan Department of Pediatrics University Medical centerKing Abdulla Medical CityArabian Gulf UniversityManama 26671Bahrain Department of Pediatrics Faculty of MedicineTanta UniversityTanta 31527Al GharbiaEgypt Department of Pediatrics University Medical CenterDr.Sulaiman Al-Habib Medical GroupManama 26671Bahrain Department of Pediatrics Tanta UniversityFaculty of MedicineTanta 31527AlghrabiaEgypt Department of Tropical Medicine Faculty of MedicineTanta UniversityTanta 31527AlghrabiaEgypt Department of Immunology Theodor Bilharz Research InstituteCairo 12411Egypt Department of Industrial Pharmacy Faculty of PharmacyAssiut UniversityAssiut 71515Egypt

BACKGROUND Irritable bowel syndrome(IBS)is a highly prevalent gastrointestinal disorder in children and adults,which increased over the past twenty *** Mediterranean diet is a well-known diet full of antioxidants and anti-inflammatory *** To evaluate the safety,tolerability,and effects of adherence to the Mediterranean diet on disease patterns in children and adolescents with *** This prospective,cross-sectional case-controlled study included 100 consecutive IBS patients diagnosed according to Rome IV criteria,aged 12-18 *** Group II on their regular diet for six *** IBS scores(IBS-SSS,IBS-QoL,and total score),different clinical and laboratory parameters were evaluated at the start and end of the *** The Mediterranean diet was safe and well-tolerated in IBS *** children and adolescents with good adherence to the Mediterranean diet(KIDMED Score≥8 points);group I showed significant improvement in IBS ***-SSS in the Mediterranean diet group was 237.2±65 at the beginning of the study and decreased to 163.2±33.8 at the end of the study(P0.05).The mean total IBS score in group I became 28.8±11.2 at the end of our study compared to 24.1±10.4 at the start(P<0.05)and significantly improved when compared to its level in group II at the end of the study(22.1±12.5 with

关键词： Mediterranean diet Irritable bowel syndrome Children and adolescents Safety Tolerability