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Chinese Chemical Letters 2011年第3期22卷 370-373页

作者： Sheng Qiang Nie Fen Ran Chao he Peng fei zhao Xiao Hong Wei Jie Li Chang Sheng zhao College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering Sichuan Universiry Chengdu 610065 China State Key Laboratory of Gansu Advanced Non-Ferrous Metal Materials Lanzhou University of Technology Lanzhou 730050 China

Well-defined amphiphilic tri-block copolymer PVP-b-PMMA-b-PVP was prepared for the first time via successive reversible addition fragmentation chain transfer（RAFT） polymerization using carboxyl-terminated trithiocarbonate as the RAFT *** structure of the copolymer was characterized using FTIR,GPC and ~1H *** block copolymer could be directly blended with polyethersulfone（PES） as a macromolecule additive using N-methyl-2-pyrrolidone（NMP） as the solvent to prepare membranes. The water contact angles for the modified membranes decreased obviously,and therefore,the protein adsorption amount on the membrane surface decreased.

关键词： Polyethersulfone membrane Protein adsorption Surface modification PVP-b-PMMA-b-PVP

Subretinal fibrosis secondary to neovascular age-related macular degeneration:mechanisms and potential therapeutic targets

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Neural Regeneration Research 2025年第2期20卷 378-393页

作者： Jingxiang Zhang Xia Sheng Quanju Ding Yujun Wang Jiwei zhao Jingfa Zhang Department of Ophthalmology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Urology People’s Hospital of Huangdao DistrictQingdaoShandong ProvinceChina Department of Ophthalmology Shanghai General Hospital(Shanghai First People’s Hospital)Shanghai Jiao Tong University School of MedicineShanghaiChina National Clinical Research Center for Eye Diseases Shanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghaiChina

Subretinal fibrosis is the end-stage sequelae of neovascular age-related macular *** causes local damage to photoreceptors,retinal pigment epithelium,and choroidal vessels,which leads to permanent central vision loss of patients with neovascular age-related macular *** pathogenesis of subretinal fibrosis is complex,and the underlying mechanisms are largely ***,there are no effective treatment options.A thorough understanding of the pathogenesis of subretinal fibrosis and its related mechanisms is important to elucidate its complications and explore potential *** current article reviews several aspects of subretinal fibrosis,including the current understanding on the relationship between neovascular age-related macular degeneration and subretinal fibrosis;multimodal imaging techniques for subretinal fibrosis;animal models for studying subretinal fibrosis;cellular and non-cellular constituents of subretinal fibrosis;pathophysiological mechanisms involved in subretinal fibrosis,such as aging,infiltration of macrophages,different sources of mesenchymal transition to myofibroblast,and activation of complement system and immune cells;and several key molecules and signaling pathways participating in the pathogenesis of subretinal fibrosis,such as vascular endothelial growth factor,connective tissue growth factor,fibroblast growth factor 2,platelet-derived growth factor and platelet-derived growth factor receptor-β,transforming growth factor-βsignaling pathway,Wnt signaling pathway,and the axis of heat shock protein 70-Toll-like receptors 2/*** review will improve the understanding of the pathogenesis of subretinal fibrosis,allow the discovery of molecular targets,and explore potential treatments for the management of subretinal fibrosis.

关键词： choroidal neovascularization epithelial-mesenchymal transition mesenchymal transition myofibroblast neovascular age-related macular degeneration submacular fibrosis subretinal fibrosis therapeutic targets transforming growth factor-β vascular endothelial growth factor

hepatoid adenocarcinoma of the stomach with neuroendocrine differentiation:A case report and review of literature

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World Journal of Clinical Cases 2023年第22期11卷 5329-5337页

作者： he fei Ze-Feng Li Ying-Tai Chen Dong-Bing zhao Department of Pancreatic and Gastric Surgical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Both hepatoid adenocarcinoma of the stomach(HAS)and neuroendocrine differentiation(NED)are rare histological subtypes of gastric cancer with unique clinicopathological features and unfavorable *** with NED is even *** SUMMARY here,we report a 61-year-old man with HAS with NED,as detected by gastric wall thickening by positron emission tomography/computed tomography for a pulmonary *** gastrectomy was performed,and pathological examination led to the diagnosis of HAS with ***,liver metastases occurred 6 mo later despite adjuvant chemotherapy,and the patient died 27 mo *** We treated a patient with HAS with NED who underwent adjuvant chemotherapy after radical surgery and still developed liver *** first report the detailed processes of the treatment and development of HAS with NED,providing an important reference for the clinical diagnosis and treatment of this condition.

关键词： Gastric cancer hepatoid adenocarcinoma Neuroendocrine differentiation Liver metastasis Case report

Inferring diffusion networks with life stage heterogeneity

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Science China(Information Sciences) 2018年第9期61卷 5-20页

作者： Tong zhao Guojie SONG Xinran he Key Laboratory of Machine Perception (MOE) Peking University Computer Science Department University of Southern California

A network inference problem focuses on discovering the structure of a diffusion network from observed cascades. This problem is significantly more challenging in several settings in which this type of an inference is desirable or necessary because of heterogeneity in the diffusion process. The heterogeneity of the diffusion process in different life stages results in the inaccuracy of a common assumption of constant influence strength. In this study, a Life Stage heuristic(LSH) method is proposed to model life stage heterogeneity by decoupling the popularity level of an item under propagation from a true strength of social ties to improve inference accuracy. The proposed LSH is incorporated into almost all existing state-of-the-art network inference algorithms to improve estimation accuracy with only minimal changes in the implementation and maintaining the same running time. Additionally, Net Rate, Net Inf, and Con NIe are used as three examples to demonstrate the power of the proposed method. Furthermore, clustering of cascades prior to the LSH is proposed to eliminate noise, and the optimized method is termed as Clustered Life Stage heuristic(CLSH).Extensive experiments on synthetic and real world datasets indicate that both LSH and CLSH methods significantly improve the accuracy of network inference.

关键词： network inference life stage heterogeneity social influence information diffusion clustering cascade

Reasoning about actions with loops via Hoare logic

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Frontiers of Computer Science 2016年第5期10卷 870-888页

作者： Jiankun he Xishun zhao Institute of Logic and Cognition Sun Yat-sen University Guangzhou 512075 China

Plans with loops are more general and compact than classical sequential plans, and gaining increasing atten- tions in artificial intelligence （AI）. While many existing ap- proaches mainly focus on algorithmic issues, few work has been devoted to the semantic foundations on planning with loops. In this paper, we first develop a tailored action lan- guage , together with two semantics for handling do- mains with non-deterministic actions and loops. Then we propose a sound and （relative） complete Hoare-style proof system for efficient plan generation and verification under O- approximation semantics, which uses the so-called idea off- line planning and on-line querying strategy in knowledge compilation, i.e., the agent could generate and store short proofs as many as possible in the spare time, and then per- form quick query by constructing a long proof from the stored shorter proofs using compositional rule. We argue that both our semantics and proof system could serve as logical foun- dations for reasoning about actions with loops.

关键词： action language plan generation plan verification loop-plan Hoare logic

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Acta Mathematica Sinica,English Series 2014年第10期30卷 1689-1697页

作者： Zhe DONG Ya fei zhao Department of Mathematics Zhejiang University

In this note, we show that avon Neumann algebra M is injective if and only if the weak＊ similarity degree d.（M） ≤ 2.

关键词： Weak* similarity degree injective von Neumann algebra operator space

Multiple lump molecules and interaction solutions of the Kadomtsev-Petviashvili Ⅰ equation

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Communications in Theoretical Physics 2022年第10期74卷 37-42页

作者： Zhonglong zhao Lingchao he College of Mathematics North University of ChinaTaiyuanShanxi 030051China College of Mathematics Taiyuan University of TechnologyTaiyuanShanxi 030024China

In this paper,a modified version of the solution in form of a Gramian formula is employed to investigate a new type of multiple lump molecule solution of the Kadomtsev–Petviashvili I *** high-order multiple lump molecules consisting of M N-lump molecules are constructed by means of the Mth-order determinant and the non-homogeneous polynomial in the degree of *** interaction solutions describing P line solitons radiating P of the M N-lump molecules are *** dynamic behaviors of some specific solutions are analyzed through numerical *** the results will enrich our understanding of the multiple lump waves of the Kadomtsev–Petviashvili I equation.

关键词： multiple lump molecules KPI equation interaction solutions

Effects of Shot Peening Process on Thermal Cycling Lifetime of TBCs Prepared by EB-PVD

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Chinese Journal of Aeronautics 2007年第2期20卷 145-147页

作者： ZHOU zhao-hui GONG Sheng-kai LI he-fei XU Hui-bin ZHANG Chun-gang WANG Lu School of Materials Science and Engineering Beij＇ing University of Aeronautics and Astronautics Beij＇ing 100083 China Shenyang Liming.4ero-Engine Group Corporation Shenyang 110043 China

Conventional two-layered thermal barrier coatings （TBCs） are prepared by electron beam physical vapor deposition （EB-PVD） with ZrO2-8 wt% Y2O3 （8YSZ） as top coat and CoCrAlY as bond coat on disk-shaped Ni based super-alloy. In this paper, three kinds of shot peening process with different lengths of operating time were adopted for bond coating. As a result, changes took place in its surface roughness and the surface micro-hardness. A thermal cycling test at 1 273 Kx55 rain and another at room temperature for 5 min were performed to study the effects of shot peening process on the thermal cycling lifetime of TBCs. It is found that a moderate shot peening process will be able to prolong the life time. The oxidation dynamic of the as-processed TBCs basically accords with the parabolic rule, and the oxidation test also attests to the spallation between YSZ and thermal growth oxide （TGO） responsible mainly for the failure of TBCs.

关键词： thermal cycling lifetime shot peening thermal barrier coatings (TBCs)

Separation performance of fine low-rank coal by vibrated gas-solid fluidized bed for dry coal beneficiation

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Particuology 2015年第6期13卷 100-108页

作者： Jingfeng he Yuemin zhao Jie zhao Zhenfu Luo Chenlong Duan Yaqun he School of Chemical Engineering and Technology Chino University of Mining and Technology Xuzhou 221116 China

Vibrational energy was introduced to a dense medium gas-solid fluidized bed to improve the separation performance of 1-6 mm fine low-rank coal. The setup was termed a vibrated gas-solid fluidized bed and could provide a stable fluidization state and uniform density distribution for dry coal beneficiation by the transfer of vibrational energy and the interaction between vibrations and the gas phase. Favorable segregation of the ash content of the 1-6-ram-sized lignite samples is achieved under suitable operating conditions. Higher yields of cleaning coal were acquired when the ash content was reduced. The probable error values were 0.065 and 0.055 at separating densities of 1.68 and 1.75 g/clTl3 for the 1-3- and 3-6-mm- sized lignite samples, respectively. Effective beneficiation of 1-6-ram-sized fine lignite could be achieved using the vibrated gas-solid fluidized bed, which provides an alternative technique for the separation of fine low-rank coal in arid areas.

关键词： Lignite Vibrational energyGas-solid fluidized bedSegregationSeparation performance

Information and knowledge behind data from underground rock grouting

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Journal of Rock Mechanics and Geotechnical Engineering 2021年第6期13卷 1326-1339页

作者： fei Xiao Qian Liu Zhiye zhao Department of Civil Engineering Nanjing University of Aeronautics and AstronauticsNanjing210016China School of Civil and Environmental Engineering Nanyang Technological University50 Nanyang Avenue639798Singapore

Data related to the pre-grouting work of a large underground project are systematically analyzed to reveal the mechanism behind,to shed some light on the execution of practical grouting,and to enrich the theory of engineering *** is generally taken as an effective way for controlling nonignorable water seepage during underground rock *** various models have been developed to guide grouting design or to specify criteria for grouting stop,it does not change the fact that grouting is still highly ***,explanation of the current situation due to grouting complexity is given through step-by-step data analysis,where the impact on grouting parameters from the geological and hydrogeological conditions is investigated,and the grouting features of two tunnels located at the same depth below the sea surface are compared and ***,the data from individual grout hole are used to construct the regional geological conditions via inverse *** is found that grouting of fractured rock masses is accompanied with great uncertainty,and field grouting data can contribute significantly to a better understanding of the regional geological conditions around an underground tunnel or rock cavern.

关键词： Field grouting data Water seepage Rock grouting Inverse modelling Data analytics Geological conditions