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Discrete element modeling and verification of the simulation parameters for chopped hybrid Broussonetia papyrifera stems

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 23-32页

作者： Caiwang Peng Junwei Chen xi he Songlin Sun Yulong Yin Zhong Chen College of Mechanical and Electrical Engineering Hunan Agricultural UniversityChangsha 410128China College of Animal Science and Technology Hunan Agricultural UniversityChangsha 410128China Rongcheng Gouyang Modern Agriculture(Chongqing)Co. LtdChongqing 500153China

In this study,the discrete element software EDEM was applied to establish a simulation model of non-uniform-sized particle units for Broussonetia papyrifera stalks,which aimed to address the low utilization rate of existing Broussonetia papyrifera harvesting machinery,the significant variation between the simulated model of Broussonetia papyrifera stalks and their actual appearance,as well as the absence of contact parameter *** a combination of the free-fall collision method,inclined plane sliding method,and inclined plane rolling method,numerical simulation was conducted to analyze the pattern of variations in contact parameters between Broussonetia papyrifera stalks and the steel material of the ***,these parameters were *** results showed that the coefficient of restitution between Broussonetia papyrifera stalks and steel materials was 0.321,the static friction factor was 0.589,and the rolling friction factor was *** the parameters of contact between Broussonetia papyrifera stalks as variables and the experimentally measured pile angle as the objective of optimization,the steepest ascent experiment and the three-factor five-level rotation combination experiment were *** this way,a second-order response model was constructed to analyze the relationship between the contact parameters and the pile *** the optimization analysis of experimental data,it was determined that the coefficient of restitution between Broussonetia papyrifera stalks was 0.21,the static friction factor was 0.24,and the rolling friction factor was ***,the calibration results were validated through experimentation to show that the relative error between the obtained pile angle under the context of optimal parameter combination and the actual one was 4.11%.In addition,the relative error of mass flow rate in spiral transport was within a reasonable range,this study lays a foundation both theoretically and statistic

关键词： hybrid Broussonetia papyrifera stem discrete element method repose angle contact parameters calibration

Graded heterojunction Improves Wide-Bandgap Perovskite for Highly Efficient 4-Terminal Perovskite/Silicon Tandem Solar Cells

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Research 2024年第2期2023卷 181-190页

作者： Wenming Chai Lindong Li Weidong Zhu Dazheng Chen Long Zhou he xi Jincheng Zhang Chunfu Zhang Yue Hao State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology&Shaanxi Joint Key Laboratory of Graphene School of MicroelectronicsXidian UniversityXi'anShaanxi 710071China xi'an Baoxin Solar Technology Co. Ltd.Xi'an710071China

Wide-bandgap(WBG)perovskite solar cells(PSCs)are essential for highly efficient and stable silicon/perovskite tandem solar *** this study,we adopted a synthetic strategy with lead thiocyanate(Pb(SCN)_(2))additive and methylammonium chloride(MACl)posttreatment to enhance the crystallinity and improve the interface of WBG perovskite films with a bandgap of 1.68 *** excessive PbI_(2)was formed at grain boundaries and converted into MAPbI_(3-x)Cl_(x)perovskites,which are utilized to form the graded heterojunction(GHJ)and compressive *** is beneficial for passivating nonradiative recombination defects,suppressing halide phase segregation,and facilitating carrier ***,the device with GHJ delivered a champion efficiency of 20.30%and superior stability in ambient air and under 85℃.Finally,we achieved a recorded efficiency of 30.91%for 4-terminal WBG perovskite/TOPCon tandem silicon solar *** findings demonstrate a promising approach for fabricating efficient and stable WBG PSCs through the formation of GHJ.

关键词： perovskite Graded Highly

Long noncoding RNA protein-disulfide isomerase-associated 3 regulated high glucose-induced podocyte apoptosis in diabetic nephropathy through targeting miR-139-3p

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World Journal of Diabetes 2024年第2期15卷 260-274页

作者： Yin-xi he Ting Wang Wen-xian Li Yan-xia Chen Department of Orthopaedic Trauma The Third Hospital of ShijiazhuangShijiazhuang 050000Hebei ProvinceChina Department of Endocrinology The Second Hospital of Hebei Medical UniversityShijiazhuang 050000Hebei ProvinceChina Department of Endocrinology The First Hospital of ZhangjiakouZhangjiakou 075000Hebei ProvinceChina

BACKGROUND Podocyte apoptosis plays a vital role in proteinuria pathogenesis in diabetic nephropathy(DN).The regulatory relationship between long noncoding RNAs(lncRNAs)and podocyte apoptosis has recently become another research hot spot in the DN *** To investigate whether lncRNA protein-disulfide isomerase-associated 3(Pdia3)could regulate podocyte apoptosis through miR-139-3p and revealed the underlying *** Using normal glucose or high glucose(HG)-cultured podocytes,the cellular functions and exact mechanisms underlying the regulatory effects of lncRNA Pdia3 on podocyte apoptosis and endoplasmic reticulum stress(ERS)were *** Pdia3 and miR-139-3p expression were measured through quantitative real-time polymerase chain *** cell viability was detected through the cell counting kit-8 colorimetric *** podocyte apoptosis rate in each group was measured through flow *** interaction between lncRNA Pdia3 and miR-139-3p was examined through the dual luciferase reporter ***,western blotting was performed to detect the effect of lncRNA Pdia3 on podocyte apoptosis and ERS via *** The expression of lncRNA Pdia3 was significantly downregulated in HG-cultured ***,lncRNA Pdia3 was involved in HG-induced podocyte ***,the dual luciferase reporter assay confirmed the direct interaction between lncRNA Pdia3 and *** Pdia3 overexpression attenuated podocyte apoptosis and ERS through miR-139-3p in HG-cultured *** Taken together,this study demonstrated that lncRNA Pdia3 overexpression could attenuate HG-induced podocyte apoptosis and ERS by acting as a competing endogenous RNA of miR-139-3p,which might provide a potential therapeutic target for DN.

关键词： Long noncoding RNAs Diabetic nephropathy Podocyte apoptosis Endoplasmic reticulum stress Competing endogenous RNA

Sensing properties and mechanisms of LaF_(3)-Co_(3)O_(4) nanorods for low-concentration methanol detection

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Rare Metals 2024年第5期43卷 2193-2204页

作者： xiao-xi he Hong-Feng Chai Yi-Wen Zhou Ke-Wei Liu Ze-xin Yu Chao Zhang College of Mechanical Engineering Yangzhou UniversityYangzhou225127China Institutefor Manufacturing Technologies of Ceramic Components and Composites(IMTCCC) University of Stuttgart70569 StuttgartGermany

Methanol is one of the characteristic gases that distinguish between healthy individuals and lung cancer(LC)lesions in exhaled human *** concentration in exhaled breath is generally below one part per million(1×10^(-6)).The second-phase composite is widely regarded as one of the methods to improve the gas-sensing perfor-mance of metal oxide semiconductor(MOS)*** this study,LaF_(3)-Co_(3)O_(4) was synthesized by a simple hydrothermal method to enhance its low-concentration methanol gas-sensing performance.5 at%LaF_(3)-Co_(3)O_(4) nanorods exhibited excellent methanol detection performance,including a wider linear detection concentration range(0.2×10^(-6)~5×10^(-6)),a response value exceeding 4.0 for 1×10^(-6)methanol at 275°C and 75%relative humidity(RH),long-term stability(maximum deviation within 15%over 2 weeks),and excellent *** mechanism of performance enhancement was studied using various techniques,and density functional *** special spinel structure of Co_(3)O_(4),the high ionic migration of F-in LaF_(3),the larger specific surface area of 5 at%LaF_(3)-Co_(3)O_(4) nanorods,and the generated crystal defects all explain the excellentmethanol gas-sensing *** work provides a novel route to prepare MOS composite materials for low-concentration methanol gas detection.

关键词： Gas sensor LaF_(3) Co_(3)O_(4) Methanol Lung cancer

Accelerated Sequential Deposition Reaction via Crystal Orientation Engineering for Low-Temperature,High-Efficiency Carbon-Electrode CsPbBr3 Solar Cells

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Energy & Environmental Materials 2024年第1期7卷 172-179页

作者： Zeyang Zhang Weidong Zhu Tianjiao Han Tianran Wang Wenming Chai Jiaduo Zhu he xi Dazheng Chen Gang Lu Peng Dong Jincheng Zhang Chunfu Zhang Yue Hao State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology & Shaanxi Joint Key Laboratory of Graphene School of Microelectronics Xidian University Guangzhou Wide Bandgap Semiconductor Innovation Center Guangzhou institute of technology Xidian University Qinghai Huanghe Hydropower Development CO. LTD.

Low-temperature,ambient processing of high-quality CsPbBr3films is demanded for scalable production of efficient,low-cost carbon-electrode perovskite solar cells（PSCs）.herein,we demonstrate a crystal orientation engineering strategy of PbBr2precursor film to accelerate its reaction with CsBr precursor during two-step sequential deposition of CsPbBr3films.

关键词： carbon-electrode perovskite solar cells crystal orientation engineering CsPbBr3 low temperature two-step sequential deposition

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多晶材料散射模型及识别实验研究

物理学报 2024年第3期73卷 134-142页

作者：刘昱贺西平贺升平陕西师范大学物理学与信息技术学院陕西省超声重点实验室西安710119 泸州高新技术研究所泸州646000

超声波识别在国防、军事、航空航天、核设施等高科技领域具有重要的应用价值.利用超声波可以实现对个体金属材料的识别,但现有研究侧重于识别材料超声信号差异的算法,缺乏识别机理.本文以2A12铝合金为例,利用6个晶粒在尺寸、形状、排布... 详细信息

超声波识别在国防、军事、航空航天、核设施等高科技领域具有重要的应用价值.利用超声波可以实现对个体金属材料的识别,但现有研究侧重于识别材料超声信号差异的算法,缺乏识别机理.本文以2A12铝合金为例,利用6个晶粒在尺寸、形状、排布方向以及排列顺序不同时,建立了10个2A12铝合金微结构的初级模型,以此类比多晶金属材料的复杂微观结构.利用Comsol有限元软件仿真计算了金属材料不同微观结构中的超声波时域信号,并将回波信号中的的背向散射信号提取为超声指纹.定义了特征差异Q,量化了具有不同微结构的散射模型间的超声指纹的差异.结果表明,微观结构的细微变化也会导致超声信号出现差异,其中晶粒尺寸的变化对信号的影响更为显著.随后提出了超声识别算法,并对4块形状完全一致的2A12铝合金样品进行了识别实验.识别结果表明,利用超声指纹可以准确识别出目标样品,且各样品间的超声指纹有显著区别.最后对样品进行了扫描电子显微镜实验,所得电子显微镜图片显示了各样品真实微观结构的形貌与差异,证实了所建立的超声散射模型的有效性.

关键词：超声散射微观结构多晶材料超声识别有限元方法

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A novel deep generative model for mRNA vaccine development: Designing 5′ UTRs with N1-methyl-pseudouridine modification

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1814-1826页

作者： xiaoshan Tang Miaozhe Huo Yuting Chen Hai Huang Shugang Qin Jiaqi Luo Zeyi Qin xin Jiang Yongmei Liu xing Duan Ruohan Wang Lingxi Chen Hao Li Na Fan Zhongshan he xi he Bairong Shen Shuai Cheng Li xiangrong Song Institute of Systems Genetics Department of Critical Care MedicineFrontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610000China Department of Computer Science City University of Hong KongHong Kong 99907China Department of Biology Brandeis UniversityBostonMA 02453USA

Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA ***,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation efficiency of the 5'*** discovered that the optimal 5'UTR for m1y-modified mRNA(m1y-5'UTR)differs significantly from its unmodified counterpart,high-lighting the need for a specialized tool for designing mly-5'UTRs rather than directly utilizing high-expression endogenous gene 5'*** response,we developed a novel machine learning-based tool,Smart5UTR,which employs a deep generative model to identify superior m1y-5'UTRs in *** tailored loss function and network architecture enable Smart5UTR to overcome limitations inherent in existing *** a result,Smart5UTR can successfully design superior 5'UTRs,greatly benefiting mRNA vaccine ***,Smart5UTR-designed superior 5'UTRs significantly enhanced antibody titers induced by COVID-19 mRNA vaccines against the Delta and Omicron variants of SARS-CoV-2,surpassing the performance of vaccines using high-expression endogenous gene 5'UTRs.

关键词： mRNA vaccine Machine learning 5'UTR mRNA design Sequence design N1-Methyl-pseudouridine COVID-19 SARS-CoV-2

实体与程序双重视角下股东权益的司法保护——以“股东代表诉讼”为切入点

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法学论坛 2024年第1期39卷 103-114页

作者：贺茜中国海洋大学法学院山东青岛266100

公司法赋予股东诉权以保护自身权益,遏制权利滥用,股东代表诉讼已成为化解有限责任公司股东利益冲突的重要手段。司法实践分析表明,股东代表诉讼前置程序的定位、损害赔偿请求的归属以及裁判效力的主观范围等在实体上和程序上均有争议... 详细信息

公司法赋予股东诉权以保护自身权益,遏制权利滥用,股东代表诉讼已成为化解有限责任公司股东利益冲突的重要手段。司法实践分析表明,股东代表诉讼前置程序的定位、损害赔偿请求的归属以及裁判效力的主观范围等在实体上和程序上均有争议。从实体法理论角度而言,立基于股份有限公司的理论预设无法与两权分离不明显的有限责任公司融洽,致使股东代表诉讼无法发挥保护公司和股东利益的制度目的,股东提起诉讼激励不足。从程序法理论角度而言,作为特殊诉讼形态的股东代表诉讼亦需与我国诉讼理论相融合。然而,既有理论无法通过诉讼担当完整表达有限责任公司股东代表诉讼的双重利益性,未能合理配置特定股东的诉讼实施权,诉讼成本与诉讼收益不匹配。在有限责任公司内部治理陷入困境的情形下,应当对股东权益进行穿透式司法保护,允许法官直接豁免前置程序,赋予原告股东基于持股比例的胜诉利益分取请求权,方能给予弱势股东实质性救济。

关键词：股东代表诉讼少数股东诉讼担当前置程序

契约法与组织法双重视角下股权赠与的效力认定

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北京理工大学学报（社会科学版） 2024年第3期26卷 88-100页

作者：贺茜中国海洋大学法学院山东青岛266100

采用单一视角认定股权赠与效力,影响《民法典》与《公司法》的衔接适用,损害公司与股东利益。有必要以契约法与组织法的双重视角研判股权赠与的效力。股权赠与合同中赠与合意的认定应加入公司治理利益的考量。股权赠与不适用优先购买权... 详细信息

采用单一视角认定股权赠与效力,影响《民法典》与《公司法》的衔接适用,损害公司与股东利益。有必要以契约法与组织法的双重视角研判股权赠与的效力。股权赠与合同中赠与合意的认定应加入公司治理利益的考量。股权赠与不适用优先购买权规则,其本身不会损害有限公司的人合性。股权赠与应采公司认可生效主义的股权变动模式,由公司对股权赠与进行合规审查,认可后即完成交付。对于滥用股权赠与规避优先购买权的行为,不发生赠与的法律效力。为防止股东利用股权赠与逃避出资义务,股权赠与完成后应由受赠人履行出资义务,由赠与人承担补充出资责任。

关键词：赠与合同优先购买权股权变动模式滥用权利