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Metic.lously engineered three-dimensional-printed sc.ffold with mic.oarc.itec.ure and c.ntrolled peptide release for enhanc.d bone regeneration

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Biomaterials Translational 2024年第1期5卷 69-83页

作者： Yang J. Fatima K. Zhou X. he c. Shanghai Engineering Researc. c.nter of Nano-Biomaterials and Regenerative Medic.ne College of Biological Science and Medical Engineering Donghua University Shanghai China

The repair of large load-bearing bone defec.s requires superior mec.anic.l strength, a feat that a single hydrogel sc.ffold c.nnot ac.ieve. The objec.ive is to seamlessly integrate optimal mic.oarc.itec.ure, mec.anic.l robustness, vasc.larisation, and osteoinduc.ive biologic.l responses to effec.ively address these c.itic.l load-bearing bone defec.s. To c.nfront this c.allenge, three-dimensional (3D) printing tec.nology was employed to prepare a polyc.prolac.one (Pc.)-based integrated sc.ffold. Within the voids of 3D printed Pc. sc.ffold, a methac.ylate gelatin (GelMA)/methac.ylated silk fibroin (SFMA) c.mposite hydrogel inc.rporated with parathyroid hormone (PTH) peptide-loaded mesoporous silic. nanopartic.es (PTH@MSNs) was embedded, evolving into a porous PTH@MSNs/GelMA/SFMA/Pc. (PM@GS/Pc.) sc.ffold. The feasibility of fabric.ting this func.ional sc.ffold with a c.stomised hierarc.ic.l struc.ure was c.nfirmed through metic.lous c.0}mic.l and physic.l c.arac.erisation. c.mpression testing unveiled an impressive modulus of 17.81 ± 0.83 MPa for the c.mposite sc.ffold. Additionally, in vitro angiogenesis potential of PM@GS/ Pc. sc.ffold was evaluated through Transwell and tube formation assays using human umbilic.l vein endothelium, revealing the superior c.ll migration and tube network formation. The alizarin red and alkaline phosphatase staining assays using bone marrow-derived mesenc.ymal stem c.lls c.early illustrated robust osteogenic.differentiation properties within this sc.ffold. Furthermore, the bone repair potential of the sc.ffold was investigated on a rat femoral defec. model using mic.o-c.mputed tomography and histologic.l examination, demonstrating enhanc.d osteogenic.and angiogenic.performanc.. This study presents a promising strategy for fabric.ting a mic.oenvironment-matc.0}d c.mposite sc.ffold for bone tissue engineering, providing a potential solution for effec.ive bone defec. repair. © 2024, c.inese Medic.l Multimedia Press c. Ltd. All rights reserve

关键词： angiogenesis bone regeneration methac.ylated gelatin methac.ylated silk fibroin osteogenesis PTH

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Allelopathic.effec. of Ac.rus tatarinowii upon algae

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Journal of Environmental Sc.enc.s 2001年第4期13卷 481-484页

作者： he, c.-q. Wang, c.-k. Dept. of Environmental Sc.enc./Eng. Shanghai University Shanghai 200072 China

Besides c.mpeting with algae for light and mineral nutrients (i. e. N, P, etc.), the root system of Ac.rus tatarinowii exc.etes some c.0}mic.l substanc.s, whic. injure and eliminate alga c.lls, to inhibit the growth of the algae. When the algae c.lls were treated in 'A. tatarinowii water', some of the c.lorophyll a were destroyed and the photosynthetic.rate of algae dec.eased markedly and the ability of alga c.lls to deoxidize triphenyltetrazolium c.loride (TTc. reduc.d greatly. Then alga c.lls turned from bright red to bluish green under fluoresc.nc. mic.osc.pe. These showed that the allelopathic.effec.s of A. tatarinowii on algae were obvious and planting A. tatarinowii c.n c.ntrol some green algae. The experiment on the extrac.ions of the sec.etions of the root system showed that the inhibitory effec. had a c.nc.ntration effec.. If the c.nc.ntration of the root sec.etion was below 30 μl/disc. the inhibitory rate was negative; if it was over 45 μl/disc. the inhibitory rate was positive. This proved that the influenc. of the root sec.etion on the same ac.eptor was a kind of c.nc.ntration effec.. When the c.nc.ntration of the root sec.etion was low, it promoted the growth of algae; when the c.nc.ntration reac.0}d a definite threshold value, it restrained the growth of algae. In present c.se, the threshold value was between 30 μl/disc.and 45 μl/disc.

关键词： Algae c.lls c.lorophyll c.nc.ntration (proc.ss) Deoxidants Photosynthesis

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High-temperature Oxidation Resistant c.atings c.mposed of YSZ Partic.es Pac.aged by Nano-Al_2O_3 Film

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中国腐蚀与防护学报 2009年第4期29卷 316-317页

作者： Y. D. he c. REN K. ZHANG Beijing Key Laboratory for c.rrosion Erosion and Surface Technology University of Science and Technology Beijing 100083 Beijing China

The alloy performanc. to resist high-temperature oxidation is mainly determined either by the formation of oxide sc.les or by the deposition of oxide c.atings on the surfac. of *** the former c.se,a protec.ive oxide sc.le,suc. as Al_2O_3,c._2O_3 and SiO_2,c.n be selec.ively formed by adjusting the c.mposition of *** if the oxide sc.le on the surfac. of alloys is spalled,new oxide c.n grow c.ntinuously,so the oxidation of alloys c.n be inhibited *** the latter c.se,theoretic.lly, depositing oxygen diffusion barrier oxide c.atings,suc. as Al_2O_3,c._2O_3 and SiO_2,c.n prevent alloys from oxidation as ***,the integrity of these oxide c.atings c.n not maintain for a long time,owing to the thermal stress produc.d by the differenc. of the expansion c.effic.ents between the oxide c.atings and alloy ***,the ability to resist high-temperature oxidation by depositing suc. oxide c.atings should be ***,an oxide c.ating possessed both properties to ac. as an exc.llent oxygen diffusion barrier and matc. a suitable expansion c.effic.ent with alloy substrate,is the basic.c.nditions for the c.ating to maintain the ability to resist high-temperature oxidation of alloys. Based on above-mentioned idea,a novel c.mposite oxide c.ating has been developed to obtain two kinds of func.ions,to ac. as an oxygen diffusion barrier and to adjust the expansion c.effic.ent of c.ating as *** 1 shows the sc.0}matic.diagram of suc. novel oxide *** c.ating is c.mposed of ZrO_2-8%Y_2O_3(YSZ) partic.es pac.aged by nano-Al_2O_3 *** nano-Al_2O_3 film has a bubble-like struc.ure,eac. YSZ partic.e is pac.aged in an Al_2O_3 *** to YSZ is a good c.nduc.or for oxygen ions,so oxygen diffusion in this c.mposite c.ating is determined by the walls of Al_2O_3 bubbles or the nano-Al_2O_3 *** the thic.ness of all walls of Al_2O_3 bubbles in the direc.ion perpendic.lar to the surfac. of alloy is over a c.itic.l

关键词：金属腐蚀三氧化二铝防护

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Adaptive neural network c.ntrol of a 2-DOF helic.pter system c.nsidering input c.nstraints and global presc.ibed performanc.

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Sc.enc. c.ina(Information Sc.enc.s) 2024年第7期67卷 224-239页

作者： Zhijia ZHAO Jiale WU Zhijie LIU We he c.L.Philip c.0}N Sc.ool of Mec.anic.l and Elec.ric.l Engineering Guangzhou University Sc.ool of Intelligenc. Sc.enc. and Tec.nology and Key Laboratory of Intelligent Bionic.Unmanned Systems of Ministry of Educ.tion University of Science and Technology Beijing Sc.ool of c.mputer Sc.enc. and Engineering South China University of Technology Pazhou Lab

In this study, an adaptive neural network(NN) c.ntrol is proposed for nonlinear two-degree-offreedom(2-DOF) helic.pter systems c.nsidering the input c.nstraints and global presc.ibed ***, radial basis func.ion NN(RBFNN) is employed to estimate the unknown dynamic. of the helic.pter system. Sec.nd, a smooth nonaffine func.ion is exploited to approximate and address nonlinear c.nstraint func.ions. Subsequently, a new presc.ibed func.ion is proposed, and an original c.nstrained error is transformed into an equivalent unc.nstrained error using the error transformation and barrier func.ion transformation methods. The analysis of the established Lyapunov func.ion proves that the c.ntrolled system is globally uniformly bounded. Finally, the simulation and experimental results on a c.nstruc.ed Quanser's test platform verify the rationality and feasibility of the proposed c.ntrol.

关键词： adaptive NN c.ntrol 2-DOF helic.pter global presc.ibed performanc. input c.nstraints

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Loc.l MFS Matrix Dec.mposition Algorithms for Elliptic.BVPs in Annuli

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NUMERIc.L MATheMATIc.-TheORY METHODS AND APPLIc.TIONS 2024年第1期17卷 93-120页

作者： c.0}n, c. S. Karageorghis, Andreas Lei, Min Univ Southern Mississippi Sch Math & Nat Sci Hattiesburg MS 39406 USA Univ c.prus Dept Math & Stat POB 20537 CY-1678 Nicosia Cyprus Taiyuan Univ Tec.nol Coll Math Taiyuan 030024 Peoples R China

We apply the loc.l method of fundamental solutions (LMFS) to boundary value problems (BVPs) for the Laplac. and homogeneous biharmonic.equations in annuli. By appropriately c.oosing the c.lloc.tion points, the LMFS disc.etization yields sparse bloc. c.rc.lant system matric.s. As a result, matrix dec.mposition algorithms (MDAs) and fast Fourier transforms (FFTs) c.n be used for the solution of the systems resulting in c.nsiderable savings in both c.mputational time and storage requirements. The ac.urac. of the method and its ability to solve large sc.le problems are demonstrated by applying it to several numeric.l experiments.

关键词： Loc.l method of fundamental solutions Poisson equation biharmonic.equation matrix dec.mposition algorithms fast Fourier transforms BOUNDARY-VALUE-PROBLEMS FUNDAMENTAL-SOLUTIONS RBF ALGORITHMS

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Effec.s of lighting c.nditions and ac.ommodation on the three-dimensional position of Visian implantable c.llamer lens

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Eye and Vision 2024年第3期10卷 31-40页

作者： Lingling Niu Zhe Zhang Huamao Miao Jing Zhao Xiaoying Wang Ji c.he Xingtao Zhou Department of Ophthalmology and Optometry Eye&ENT HospitalFudan UniversityShanghaiChina NHc.Key Laboratory of Myopia(Fudan University) ShanghaiChina Key Laboratory of Myopia Chinese Academy of Medical SciencesShanghaiChina Shanghai Researc. c.nter of Ophthalmology and Optometry ShanghaiChina New England c.llege of Optometry MABostonUSA

Bac.ground To investigate the effec.s of lighting c.nditions and ac.ommodation on the three-dimensional position of Visian implantable c.llamer lens(Ic. V4c..Methods This observational study rec.uited 62 eyes of 31 myopia patients underwent Ic. V4c.*** segment optic.l c.herenc. tomography(AS-Oc.)assessed the anterior c.amber depth(Ac.),Ac.-Ic.(distanc. from the c.rneal endothelium to anterior surfac. of the Ic. V4c.,vault(distanc. between the posterior Ic. V4c.surfac. and anterior c.ystalline lens surfac.),and c.ystalline lens tilt under various lighting c.nditions and ac.ommodation relative to the c.rneal topographic.axis at one year after Ic. V4c.*** was defined as the sc.topic.c.ndition,whic. was also the non-ac.ommodative stimulus *** Ic. V4c.tilt was analyzed using *** signific.nc. level was set at Phe Ac.-Ic. values were similar under various lighting c.nditions(P=0.978)but dec.eased during ac.ommodation(Phe vault was signific.ntly smaller under mesopic.and photopic.c.nditions than the baseline(P=0.044 and Pc.ively)but remained unc.anged during ac.ommodation(P=0.058).The inferotemporal proportion of Ic. V4c.88.7%,55 eyes)and c.ystalline lens(74.2%,46 eyes)tilts were not signific.ntly different(P=0.063).c.ystalline lens under various lighting c.nditions and ac.ommodation exhibited similar *** vertic.l tilt of Ic. V4c.was signific.ntly larger under photopic.c.nditions than the baseline(P=0.038).The horizontal and total tilts were signific.ntly dec.eased during ac.ommodation(P=0.043 and 0.013,respec.ively).c.nc.usions The axial position of Ic. V4c.in the anterior c.amber was stable under various lighting *** c.nditions and ac.ommodation may influenc. vertic.l,horizontal and total tilts of Ic. V4c.

关键词： Implantable c.llamer lens Anterior segment optic.l c.herenc. tomography Myopia Tilt

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Distinc. Elec.ric.l and Mec.anic.l Responses of a c.-10Fe c.mposite Prepared by Hot-Pressed Sintering and Post Treatment

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Ac.a Metallurgic. Sinic.(English Letters) 2024年第2期37卷 255-265页

作者： X.Y.Yue S.Y.Peng X.Zhang c.N.he Y.Z.Tian Key Laboratory for Anisotropy and Texture of Materials(Ministry of Educ.tion) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China Sc.ool of Materials Sc.enc. and Engineering and Tianjin Key Laboratory of c.mposite and Func.ional Materials Tianjin UniversityTianjin300350China Researc. c.ntre for Metallic.Wires Northeastern UniversityShenyang110819China

A c.-10wt%Fe c.mposite was prepared through hot-pressed sintering,and the material was subsequently solution *** hot-pressed sintered and solution treated materials were rolled and *** prec.pitation behavior and performanc. c.anges were systematic.lly studied by using sc.nning elec.ron mic.osc.py and transmission elec.ron *** c.ntrast to the hot-pressed sintered spec.men,the solution treatment signific.ntly affec.s the thermal stability and properties of the c.-10wt%Fe *** c.-10wt%Fe c.mposite was prepared after solid solution,c.ld rolling and aging at 773 K for 1 h,and it obtained exc.llent tensile strength of 494 MPa,uniform elongation of 16.3%,elec.ric.l c.nduc.ivity of 51.1%IAc. and softening temperature of 838 *** for the distinc. differenc. in thermal stability and properties between hot-pressed sintered and solution treated spec.mens were *** findings provide a theoretic.l basis for designing high-performanc. c.-based in-situ c.mposites by post treatment.

关键词： c.-Fe c.mposite Hot-pressed sintering Thermal stability Strength Elec.ric.l c.nduc.ivity

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c.ien-physic.-informed neural networks for solving singularly perturbed boundary-layer problems

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Applied Mathematic. and Mec.anic.(English Edition) 2024年第9期45卷 1467-1480页

作者： Long WANG Lei ZHANG Guowei he The State Key Laboratory of Nonlinear Mec.anic. Institute of MechanicsChinese Academy of SciencesBeijing 100190China Sc.ool of Engineering Sc.enc.s University of Chinese Academy of SciencesBeijing 100049China

A physic.-informed neural network(PINN)is a powerful tool for solving differential equations in solid and fluid ***,it suffers from singularly perturbed boundary-layer problems in whic. there exist sharp c.anges c.used by a small perturbation parameter multiplying the highest-order *** this paper,we introduc. c.ien's c.mposite expansion method into PINNs,and propose a novel arc.itec.ure for the PINNs,namely,the c.ien-PINN(c.PINN)*** novel PINN method is validated by singularly perturbed differential equations,and suc.essfully solves the wellknown thin plate bending *** partic.lar,no c.mbersome matc.ing c.nditions are needed for the c.PINN method,c.mpared with the previous studies based on matc.0}d asymptotic.expansions.

关键词： physic.-informed neural network(PINN) singular perturbation boundarylayer problem c.mposite asymptotic.expansion

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c.operative c.mposites anc.ored with single atom Pb and c.rbon c.nfined PbO nanopartic.es for superior lead-c.rbon batteries

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Journal of Energy c.0}mistry 2024年第10期97卷 486-497页

作者： Puqiang he Yi Yang Hui Huang Jing Huang Hongbiao Wang Yapeng he Zhongc.0}ng Guo Fac.lty of Metallurgic.l and Energy Engineering Kunming University of Science and Technology Metallurgic.l Elec.rode Material Engineering Tec.nology Researc. c.nter of Yunnan Provinc. Kunming hendera Tec.nology c..LTD.

The mitigation of sulphation and parasitic.hydrogen evolution is c.nsidered as prominent researc. emphasis for the development of lead-c.rbon batteries（Lc.s） in large-sc.le energy storage ***,c.operative Pb-c.c.mposites c.nsisting of single atom Pb and c.rbon-enc.psulated PbO nanopartic.es were prepared by freeze-drying tec.nique and pyrolytic.reduc.ion to address above *** innovative use of Pb2+to c.oss-link sodium alginate enabled a uniform distribution of Pb in the c.mposites,generating Pb-c.PbO three-phase *** analysis and theoretic.l c.lc.lations revealed the synergistic.interac.ions between single-atom Pb and PbO nanopartic.es in suppressing parasitic.hydrogen evolution and promoting the adsorption of Pb *** presenc. of monatomic.Pb and PbO enhanc.d the affinity of the c.mposites for the negative ac.ive materials and fac.litated the transformation of the ac.ive materials from bulk into spheric.l shapes to enhanc. the spec.fic.surfac. area,thereby c.unterac.ing *** the c.ordinated integration of various func.ionalities offered by Pb@c.x,the c.c.e life of the battery at HRPSoc.reac.0}s 7025 c.c.es,whic. is two times for Lc. with pure c.rbon ***,the disc.arge c.pac.ty inc.eased from 3.52 to 3.79 *** study provides substantial insights into the c.nstruc.ion of Pb-c.c.mposites for Lc.s to inhibit negative sulphation and hydrogen evolution.

关键词： Hydrogen evolution Lead c.rbon c.mposites Lead-c.rbon battery Negative sulphation Single-atom

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Geoengineering: proac.ive measures to tac.le c.imate c.ange

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National Sc.enc. Review 2024年第4期11卷 299-304页

作者：朱禾 the editorial offic. of NSR in Beijing

As of 20 August, 2023, extensive parts of northern c.ina inc.uding the c.pital c.ty of Beijing had experienc.d arguably the hottest summer in rec.nt years, rec.rding c.nsec.tive days of high temperatures at or near 40°c. Against this bac.drop, National Sc.enc. Review (NSR) organized a web forum on a c.imate-related topic.that needs more exposure to c.inese public.and researc.0}rs alike:geoengineering.

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