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Study of primordial deuterium abundance in Big Bang nucleosynthesis

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Nuclear Science and Techniques 2024年第3期35卷 208-215页

作者： zhi-Lin Shen Jian-jun he Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Institute of Radiation Technology Beijing Academy of Science and TechnologyBeijing 100875China

Big Bang nucleosynthesis(BBN)theory predicts the primordial abundances of the light elements^(2) H(referred to as deuterium,or D for short),^(3)he,^(4)he,and^(7) Li produced in the early *** these,deuterium,the first nuclide produced by BBN,is a key primordial material for subsequent *** date,the uncertainty in predicted deuterium abundance(D/H)remains larger than the observational *** this study,the Monte Carlo simulation code PRIMAT was used to investigate the sensitivity of 11 important BBN reactions to deuterium *** found that the reaction rate uncertainties of the four reactions d(d,n)^(3)he,d(d,p)t,d(p,γ)^(3)he,and p(n,γ)d had the largest influence on the calculated D/H ***,the calculated D/H uncertainty cannot reach observational precision even with the recent LUNA precise d(p,γ)^(3) he *** the nuclear physics aspect,there is still room to largely reduce the reaction-rate uncertainties;hence,further measurements of the important reactions involved in BBN are still necessary.A photodisintegration experiment will be conducted at the Shanghai Laser Electron Gamma Source Facility to precisely study the deuterium production reaction of p(n,γ)d.

关键词： Big Bang nucleosynthesis Abundance of deuterium Reaction cross section Reaction rate Monte Carlo method

肝性脑病临床指南和共识的质量评价及推荐意见研究

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中西医结合肝病杂志 2024年第2期34卷 140-146,152页

作者：何新张卓然贺俊芝杜宏波丁鹏康雷北京中医药大学东直门医院北京100700 湖南省直中医医院北京中医药大学肝病研究院

目的:采用AGREEⅡ和RIGHT工具对肝性脑病(he)指南性文件的方法学质量和报告质量进行评价,并对推荐意见及证据进行总结和比较,为未来he指南性文件的制定及临床实践提供参考。方法:计算机检索中国知网(CNKI)、PubMed、中国生物医学文献数... 详细信息

目的:采用AGREEⅡ和RIGHT工具对肝性脑病(he)指南性文件的方法学质量和报告质量进行评价,并对推荐意见及证据进行总结和比较,为未来he指南性文件的制定及临床实践提供参考。方法:计算机检索中国知网(CNKI)、PubMed、中国生物医学文献数据库(CBM)、维普(VIP)、万方(Wanfang)、WHO、国际指南协作网(GIN)、美国国立指南文库(NGC)、英国国家临床优化研究所(NICE)、苏格兰院际间协作网(SIGN)和医脉通数据库(Medlive),检索时限为2003年1月至2023年1月。由两名肝病研究人员独立使用AGREEⅡ和RIGHT对纳入指南性文件的方法学质量和报告质量进行评价,并对循证方法制订的指南性文件的推荐意见和证据进行整理和比较。结果:共纳入14篇文献,其中9篇指南,5篇共识;中文2篇,英文12篇;使用循证方法制订的有12篇。B级7部,C级7部。AGREEⅡ各领域平均得分分别为:范围与目的(40.87%)、参与人员(26.98%)、制订严谨性(23.96%)、表达清晰性(47.22%)、应用性(17.26%)、编辑独立性(18.75%)。RIGHT各领域平均得分分别为:基本信息(60.42%)、背景(40.85%)、证据(43.57%)、推荐意见(43.88%)、评审和质量保证(16.96%)、资金资助与利益冲突声明和管理(17.56%)、其他方面(38.10%)。主要推荐意见涉及筛查与诊断、治疗、营养管理和预防。结论:纳入的he指南性文件在方法学质量和报告质量方面整体得分较低。在方法学质量方面,参与人员、制订严谨性、应用性和编辑独立性仍有待提高。在报告质量方面,评审和质量保证,资金资助与利益冲突声明和管理领域需要进一步报告。未来可增进he放射性示踪成像和神经生理学研究,为he的主动诊断提供进一步参考,并形成“药物治疗-营养管理-复发预防”的he管理模式。

关键词：肝性脑病 AGREEⅡ RIGHT 指南性文件推荐意见

后数字艺术实践与后数字审美——以俄罗斯数字艺术为例

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河北民族师范学院学报 2024年第2期44卷 20-25页

作者：张若冰董佳婧何志钧莫斯科国立师范大学艺术学院莫斯科119991 南昌大学人文学院江西南昌330031

从20世纪90年代开始,正统主义艺术逐渐向艺术中的新物质主义方向过渡。与此同时,在“全面数字化”和大众文化占主导地位的文化环境下成长起来的新一代艺术家和设计师不约而同转向了后数字艺术实践,他们试图将当代世界呈现为一个混合多... 详细信息

从20世纪90年代开始,正统主义艺术逐渐向艺术中的新物质主义方向过渡。与此同时,在“全面数字化”和大众文化占主导地位的文化环境下成长起来的新一代艺术家和设计师不约而同转向了后数字艺术实践,他们试图将当代世界呈现为一个混合多元世界,其中数字和真实、人工和物质平等地共存,具有同等价值。后数字审美不是数字审美的终点,而是它在新条件下的延续和表现,其中的互动性特质不可忽视。结合当代艺术实践分析俄罗斯当代视觉艺术形式的最新趋势,有助于深化对俄罗斯数字艺术的认识。

关键词：数字艺术俄罗斯后数字艺术后数字审美

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燃煤电厂循环水排污水预处理系统试验与优化

四川环境 2024年第5期43卷 187-194页

作者：温佳琪何思源张静岳强何志军郭宗林河北建投工程建设有限公司石家庄050051 中国市政工程中南设计研究总院有限公司武汉430010 河北建投水务投资有限公司石家庄050051

燃煤电厂循环冷却水排污水成分复杂,污染物富集程度高。为提高预处理工艺对水中钙镁硬度、硅、有机物和悬浮物等的去除效率,确保后续深度净化单元的安全稳定运行,采用“化学软化+絮凝+沉淀”等预处理方法,对北方某电厂循环冷却水排污水... 详细信息

燃煤电厂循环冷却水排污水成分复杂,污染物富集程度高。为提高预处理工艺对水中钙镁硬度、硅、有机物和悬浮物等的去除效率,确保后续深度净化单元的安全稳定运行,采用“化学软化+絮凝+沉淀”等预处理方法,对北方某电厂循环冷却水排污水预处理系统开展了现场模拟优化试验研究。试验结果表明:Ca(OH)_(2)+Na_(2)CO_(3)和NaOH+Na_(2)CO_(3)两种碱性组合药剂中,NaOH+Na_(2)CO_(3)对该厂循环水排污水的硬度、SiO_(2)去除效果更佳,在控制最佳pH为10.5时,出水指标为Ca^(2+)≤50mg/L、Mg^(2+)≤80mg/L、SiO_(2)≤1mg/L,软化剂和絮凝剂的加药顺序对COD去除水平和沉淀效果无明显差异,COD平均去除率为18.26%,SS去除率可达到60%,形成的污泥浓度(以SS浓度计)约为5500mg/L。通过试验研究,选择最适宜的药剂、投加顺序和投加量,为水处理工艺的降本增效提供数据支撑,研究成果可为电厂废水零排放项目的方案设计提供参考。

关键词：燃煤电厂循环水排污水预处理试验研究钙镁硬度絮凝剂

Recombinant adenovirus vector Ad-hIL-10 protects grafts from cold ischemia-reperfusion injury following orthotopic liver transplantation in rats

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hepatobiliary & Pancreatic Diseases International 2010年第2期9卷 144-148页

作者： Si, Zhong-Zhou Li, Jie-Qun Qi, Hai-zhi he, zhi-jun Hu, Wei Li, Yi-Ning Cent S Univ Xiangya Hosp 2 Dept Organ Transplantat Changsha 410011 Hunan Peoples R China

BACKGROUND: Interleukin 10 (IL-10), a Th2 type cytokine, modulates inflammatory responses by inhibiting the production of proinflammatory cytokines. This study was designed to investigate the protective effects of adenovirus-mediated human IL-10 (Ad-hIL-10) gene transfer on protecting grafts from cold ischemia-reperfusion injury following orthotopic liver transplantation in rats. METHODS: Adenoviruses encoding hIL-10 or beta-galactosidase (Ad-lacZ) were injected via the superior mesenteric vein into prospective donor animals. The donor liver was harvested 48 hours after transduction, and stored for 12 hours at 4 degrees C in lactated Ringer's solution prior to transplantation. The rats were divided into saline, Ad-lacZ, and Ad-hIL-10 groups. Liver function test, histopathological examination, reverse transcriptase-polymerase chain reaction (RT-PCR), and Western blotting were performed at 24 hours after transplantation in the three groups. RESULTS: Liver function (ALT and AST) was significantly improved, and the Suzuki score was significantly decreased in the Ad-hIL-10 group. The levels of hepatic TNF-alpha, MIP-2, ICAM-1 mRNA, and NF-kappa B protein in the Ad-hIL-10 group were significantly decreased. The expression of hIL-10 mRNA was detected by RT-PCR in Ad-hIL-10-treated grafts but not in controls treated with saline or Ad-lacZ. CONCLUSIONS: Donor pretreatment with Ad-hIL-10 down-regulates the expression of proinflammatory cytokines TNF-alpha, MIP-2, and ICAM-1 mRNA. hIL-10 protects against hepatic cold ischemia-reperfusion injury, at least in part, by suppressing NF-kappa B activation and subsequent expression of proinflammatory mediators. (hepatobiliary Pancreat Dis Int 2010; 9: 144-148)

关键词： adenovirus vector interleukin 10 ischemia-reperfusion injury gene transfer

中药干预炎症细胞因子在骨关节炎中的作用研究进展

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风湿病与关节炎 2024年第6期13卷 64-68,80页

作者：魏晓涛何志军刘涛李金鹏陈杰王威威甘肃省中医院甘肃兰州730000 甘肃中医药大学甘肃兰州730000

骨关节炎是一种以累及关节疼痛剧烈为特征的常见的退行性疾病。骨关节炎发病机制复杂,与关节软骨损伤、软骨基质降解、软骨下骨重塑、炎症和软骨细胞凋亡代谢等诸多因素有关。转化生长因子-β、白细胞介素、基质金属蛋白酶、肿瘤坏死因... 详细信息

骨关节炎是一种以累及关节疼痛剧烈为特征的常见的退行性疾病。骨关节炎发病机制复杂,与关节软骨损伤、软骨基质降解、软骨下骨重塑、炎症和软骨细胞凋亡代谢等诸多因素有关。转化生长因子-β、白细胞介素、基质金属蛋白酶、肿瘤坏死因子-α、骨形态发生蛋白等细胞因子密切参与骨关节炎发生、发展。在中医学“整体观、个体化、治未病”理论和“通经活络、祛风散寒、强骨补肾”等治疗原则指导下,中医药治疗骨痹历史悠久、疗效稳定。兹通过查阅最新文献,总结上述细胞因子与骨关节炎的关系及中医药干预的最新成果,以期为骨关节炎的深入研究及临床运用中医药防治提供参考和依据。

关键词：骨关节炎细胞因子软骨修复炎症中医药

Volume of fluid simulation of single argon bubble dynamics in liquid steel under RH vacuum conditions

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Journal of Iron and Steel Research International 2024年第4期31卷 828-837页

作者： Gu-jun Chen Sheng-ping he College of Materials Science and Engineering Yangtze Normal UniversityChongqing 400044China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China

Single argon bubble dynamics in liquid steel under Ruhrstahl-heraeus(RH)vacuum conditions were simulated using the volume of fluid method,and the ideal gas law was used to consider bubble growth due to heat transfer and pressure *** simulation with a constant bubble density was also performed to validate the numerical method,and the predicted terminal bubble shape and velocity were found to agree with those presented in the Grace diagram and calculated by drag correlation,*** simulation results under RH conditions indicate that the terminal bubble shape and velocity cannot be *** primary bubble growth occurs within a rising distance of 0.3 m owing to heating by the high-temperature liquid steel;subsequently,the bubble continues to grow under equilibrium with the hydrostatic *** the initial diameter is 8-32 mm,the bubble diameter and rising velocity near the liquid surface are 80-200 mm and 0.5-0.8 m/s,*** bubble rises rectilinearly with an axisymmetric shape,and the shape evolution history includes an initial sphere,(dimpled)ellipsoid,and spherical cap with satellite bubbles.

关键词： Bubble dynamics Liquid steel Volume of fluid Bubble growth Bubble shape Rising velocity

Prediction of liquid circulation flow rate in RH degasser:improvement of decarburization at low atmospheric pressure

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Journal of Iron and Steel Research International 2024年第7期31卷 1661-1667页

The two-fluid model coupled with population balance model was used for simulating the gas-liquid flow in the Ruhrstahl-heraeus(RH)*** predicted circulation flow rate was compared with that measured from a water model experiment to validate the mathematical ***,influence of snorkel immersion depth on liquid circulation flow rate was numerically investigated under an atmospheric pressure of 101 and 84 kPa,*** result indicates that the circulation flow rate of the RH degasser in the high-altitude area was severely reduced because of the decrease in atmospheric ***,increasing the snorkel immersion depth from 0.5 to 0.7 m can compensate for the decrease in atmospheric *** test result indicates that decarburization rate is significantly enhanced by increasing the snorkel immersion *** optimization,the percentage of heats with a final carbon content less than 0.002 wt.%is significantly increased from 22.0%to 96.4%.

关键词： RH degasser Two-fluid model Population balance model-Circulation flow rate Decarburization Snorkel immersion depth

Equivalence between the internal observability and equation

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Applied Mathematics(A Journal of Chinese Universities) 2024年第1期39卷 89-97页

作者： LIU Wen-jun TU zhi-yu School of Mathematics and Statistics Nanjing University of Information Science and TechnologyNanjing 210044China

This paper is concerned with a third order in time linear Moore-Gibson-Thompson equation which describes the acoustic velocity potential in ultrasound wave *** by the work of Kaltenbacher,Lasiecka and Marchand(Control Cybernet.2011,40:971-988),we establish an observability inequality of the conservative problem,and then discuss the equivalence between the exponential stabilization of a dissipative system and the internal observational inequality of the corresponding conservative system.

关键词： Moore-Gibson-Thompson equation internal observability exponential stability