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世界核心医学期刊文摘（儿科学分册） 2006年第2期2卷 47-48页

作者： De Backer A. Madern G.C. hazebroek f.w.j. 王经纬 Department of Pediatric Surgery Academic Hospital Free University of Brussels B-1090 Brussels Belgium

Purpose: The aim of the study was to examine the clinical presentation, method(s) of treatment, complications, and results in newborns and infants with retroperitoneal germ cell tumors (GCTs). Methods: A retrospective chart review of all patients treated between 1974 and 2002 for GCT located in the retroperitoneumin 2 institutions identified 12 patients with histologically proven retroperitoneal GCT. Vital data concerning pregnancy and delivery were analyzed. Age at diagnosis and symptoms were recorded, as well as possibly associated anomalies. Data concerning surgical treatment, perioperative and postoperative complications, histological staging, and final outcome were all analyzed. Results: In 3 patients, the diagnosis had been made antenatally between 31 and 35 weeks of gestation. In 1 patient, the diagnosis was made at birth, and in 8 later in life (ages 3, 5, 7, 8, 8, 11, 18, and 24 months). Symptoms in these 8 boys and 4 girls were abdominal distension and a palpable upper abdominal mass, right-sided in 5, left-sided in 5, and central in 2; the tumor was usually big. Associated anomalies were noted in 4 patients and were chromosomal in 3 (Down syndrome in 2 and Klinefelter syndrome in 1). One baby died of uncontrollable bleeding during an emergency operation immediately after traumatic birth. The other 11 infants survived. four other patients showed serious perioperative complications (1 caval vein tear, 1 choledochal tear, 1 cyst rupture, and 1 esophagogastric tear)which were managed without further consequences. Histologically, 4 tumors were mature teratomas, 6 were immature teratomas (grade I in 4, grade II in 1, and grade II-III in 1), and 2 were malignant yolk sac tumors (YSTs). The patients with YSTs underwent surgical biopsy, followed by chemotherapy and excision of the remaining tumor and of the metastases. No adjuvant treatment was administered in the patients with benign disease. Nine survivors with benign tumor are disease-free between 1 and 30 year

关键词：生殖细胞瘤腹膜后患者临床研究手术后并发症组织学分类唐氏综合征食管撕裂异常表现婴儿存活

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肠套叠水压灌肠复位法的成功与症状持续时间的关系

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世界核心医学期刊文摘（儿科学分册） 2006年第A3期2卷 35-36页

作者： Van Den Ende E.D. Allema j.H. hazebroek f.w.j. Breslau P.j. 王一飞 Department of Surgery Red Cross and Juliana Children' s Hospital Sportlaan 600 2566 MJ The Hague Netherlands

Background: It is widely believed that hydrostatic reduction of intussusception is less successful in children with prolonged symptoms prior to presentation. Aim: To prospectively evaluate success in relation to duration of symptoms. Methods: Prospective study in which children, regardless of symptom duration, underwent an attempt at hydrostatic reduction. Results: Of 113 children presenting with intussusception, 16 had peritonitis and required immediate laparotomy. A hydrostatic reduction was attempted in 97 and was successful in 77 (79% ). There were 26 successful reductions with symptoms with symptoms for 12-24 hours (81% ), and 21 with symptoms >24 hours (75% ). Conclusion: The success rate with hydrostatic reduction was not significantly influenced by symptom duration.

关键词：水压灌肠复位症状持续时间合并腹膜炎时间相关

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