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Capsosiphon fulvescens suppresses LPS-stimulated inflammatory responses by suppressing TLR4/NF-κB activation in RAW264.7 murine macrophages

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Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 115-126页

作者： Seon Yeong Ji EunJin Bang Hyun Hwangbo Min Yeong Kim Da Hye Kim Su Hyun Hong Shin-Hyung Park Chang-Young Kwon Gi-Young Kim You-Jin jeon Suengmok Cho Yung Hyun Choi Department of Biochemistry Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Basic Research Laboratory for the Regulation of Microplastic-Mediated Diseases and Anti-Aging Research Center Dong-eui UniversityBusan 47227Republic of Korea Department of Pathology Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Department of Oriental Neuropsychiatry Dong-eui University College of Korean MedicineBusan 47227Republic of Korea Department of Marine Life Science Jeju National UniversityJeju 63243Republic of Korea Department of Food Science and Technology/Institute of Food Science Pukyong National UniversityBusan 48513Republic of Korea

Objective:To evaluate the effects of Capsosiphon fulvescens(***)ethanolic extract on inflammation in lipopolysaccharide(LPS)-induced RAW296.7 ***:The protective effects of *** ethanolic extract on LPS-induced inflammation in RAW264.7 macrophages were assessed using biochemical analysis,including enzyme-linked immunosorbent assay,quantitative reverse transcription-polymerase chain reaction,and Western blot *** examine reactive oxygen species(ROS)production,flow cytometry analysis,and immunofluorescence staining were ***,the modulatory effect of *** ethanolic extract on NF-κB activation was ***:*** ethanolic extract significantly attenuated LPS-induced levels of pro-inflammatory cytokines and notably reduced the secretion and mRNA levels of LPS-mediated matrix *** addition,*** ethanolic extract decreased ROS production and suppressed the TLR4/NF-κB signaling ***:*** ethanolic extract alleviates inflammation as well as oxidative stress by modulating the TLR4/NF-κB signaling in LPS-induced RAW264.7 *** can be used as a potential therapeutic agent to suppress inflammation and oxidative stress-associated diseases.

关键词： Capsosiphon fulvescens Inflammation Oxidative stress NF-κB Nrf2 TLR4

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Improving ionic conductivity of von-Alpen-type NASICON ceramic electrolytes via magnesium doping

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Journal of Advanced Ceramics 2023年第5期12卷 1058-1066页

作者： Il-Seop Jang Wooseok Go Bo-Ye Song hayoung Park Yun Chan Kang Jinyoung Chun Emerging Materials R&D Division Korea Institute of Ceramic Engineering and Technology(KICET)Jinju 52851Republic of Korea Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea Energy Storage and Distribution Resources Division Lawrence Berkeley National LaboratoryBerkeley 94720USA

NASICON (sodium (Na) superionic conductor) compounds have attracted considerable attention as promising solid electrolyte materials for advanced Na-based batteries. In this study, we investigated the improvement in ionic conductivities of von-Alpen-type NASICON (vA-NASICON) ceramic electrolytes by introducing a magnesium ion (Mg^(2+)) as a heterogeneous element. The optimal Mg-doped vA-NASICON exhibited a high ionic conductivity of 3.64×10^(−3) S·cm^(−1), which was almost 80% higher than that of un-doped vA-NASICON. The changes in physicochemical properties of the vA-NASICONs through the Mg introduction were systematically analyzed, and their effects on the ionic conductivities of the vA-NASICON were studied in detail. When the optimal ratio of Mg^(2+) was used in a synthetic process, the relative density (96.6%) and grain boundary ionic conductivity (σgb) were maximized, which improved the total ionic conductivity (σt) of the vA-NASICON. However, when Mg^(2+) was introduced in excess, the ionic conductivity decreased because of the formation of an undesired sodium magnesium phosphate (NaxMgyPO_(4)) secondary phase. The results of this study are expected to be effectively applied in the development of advanced sodium-based solid electrolytes with high ionic conductivities.

关键词： NASICON solid electrolyte von-Alpen-type magnesium(Mg)doping ionic conductivity

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Flexible PVA/BMIMOTf/LLZTO composite electrolyte with liquid-comparable ionic conductivity for solid-state lithium metal battery

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Journal of Energy Chemistry 2022年第11期31卷 128-139,I0005页

作者： Hyesun jeon Hai Anh Hoang Dukjoon Kim School of Chemical Engineering Sungkyunkwan UniversitySuwonGyeonggi 16419Republic of Korea

Poly(vinyl alcohol)(PVA)/1-butyl-3-methylimidazolium trifluoromethanesulfonate(BMIMOTf)/Li_(6.4)La_(3)Zr_(1.4)Ta_(0.6)O_(12)(LLZTO)solid-state composite electrolyte(SSCE)membranes were synthesized for solid-state lithium metal battery *** garnet-type LLZTO nanoparticles were surface-coated with the polydopamine layer of 8-10 nm thickness to enhance the dispersion status of LLZTO particles in the PVA *** hydrophilic BMIMOTf ionic liquid(IL)was added along with LLZTO nanoparticles to enhance the ionic conductivity and electrochemical stability of the SSCE *** synthesized composite electrolyte membrane containing 7 wt%of LLZTO and 60 wt%of BMIMOTf showed the outstanding Li+conductivity of 2×10^(-3)S cm^(-1)and the lithium transference number of 0.76 at room temperature in the firm and flexible solid state with the tensile strength of 8 *** a high single ion conduction characteristic led to the quite low interfacial resistance of 39Ωbetween the composite electrolyte and the lithium *** to these superior properties of composite membranes,the LiFePO_(4)|SSCE|Li cell exhibited an excellent discharge capacity of 165 mAh g^(-1)at 0.2 C,maintaining the coulombic efficiency of 98%after 100 cycles at room temperature.

关键词： Polymer-matrix composites(PMCs) Interface/interphase Surface treatments Solid-state lithium-ion batteries

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The Immersed Interface Hybridized Difference Method for Parabolic Interface Problems

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Numerical Mathematics(Theory,Methods and Applications) 2022年第2期15卷 336-359页

作者： Youngmok jeon Son-Young Yi Department of Mathematics Ajou UniversitySuwon 16499Republic of Korea Department of Mathematical Sciences The University of Texas at El PasoEl PasoTX 79968USA

We propose several immersed interface hybridized difference methods(IHDMs),combined with the Crank-Nicolson time-stepping scheme,for parabolic interface *** IHDM is the same as the hybrid difference method away from the interface cells,but the finite difference operators on the interface cells are modified tomaintain the same accuracy throughout the entire *** themodification process,we consider virtual extensions of two sub-solutions in the interface cells in such a way that they satisfy certain jump equations between *** propose several different sets of jump equations and their resulting discrete methods for one-and two-dimensional *** numerical results are presented to demonstrate the accuracy and robustness of the proposed methods.

关键词： Parabolic interface problem hybrid difference method immersed interface

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Liver transplantation for patients with intrahepatic cholangiocarcinoma

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Hepatobiliary & Pancreatic Diseases International 2022年第6期21卷 590-593页

作者： Adarsh Vijay Hoonbae jeon Division of Hepato-Pancreato-Biliary&Abdominal Transplant Surgery Tulane Abdominal Transplant InstituteTulane University School of MedicineNew OrleansLA 70112-2632USA

Cholangiocarcinoma(CCA)constitutes a group of heterogeneous malignant tumors emerging in the biliary tree[1].Based on their anatomical distribution,CCA is classified into perihilar cholangio-carcinoma(pCCA),distal cholangiocarcinoma(dCCA)and intrahep-atic cholangiocarcinoma(iCCA)and they account for 60%-70%,20%-30%and 5%-10%of CCA,*** past decade has seen a 2-fold increase in annual percentage change in incidence of iCCA in USA when compared to the prior three decades[2].

关键词： carcinoma patients Liver

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Piezoresistive Prediction of CNTs-Embedded Cement Composites via Machine Learning Approaches

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Computers, Materials & Continua 2022年第4期71卷 1503-1519页

作者： Jinho Bang SongEe Park Haemin jeon School of Civil Engineering Chungbuk National UniversityCheongju28644Korea Department of Civil and Environmental Engineering Hanbat National UniversityDaejeon34158Korea

Conductive cementitious composites are innovated materials that have improved electrical conductivity compared to general types of cement,and are expected to be used in a variety of future infrastructures with unique functionalities such as self-heating,electromagnetic shielding,and *** the present study,machine learning methods that have been recently applied in various fields were proposed for the prediction of piezoelectric characteristics of carbon nanotubes(CNTs)-incorporated cement *** on the resistivity change of CNTs/cement composites according to various water/binder ratios,loading types,and CNT content were considered as training *** data were applied to numerous machine learning techniques including linear regression,decision tree,support vector machine,deep belief network,Gaussian process regression,genetic algorithm,bagging ensemble,random forest ensemble,boosting ensemble,long short-term memory,and gated recurrent units to estimate the time-independent and-dependent electrical properties of conductive cementitious *** comparing and analyzing the computed results of the proposed methods,an optimal algorithm suitable for application to CNTs-embedded cementitious composites was derived.

关键词： Machine learning long short-term memory gated recurrent units nano-composites cement matrix carbon nanotube

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Development of the reactive force field and silicon dry/wet oxidation process modeling

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npj Computational Materials 2023年第1期9卷 676-686页

作者： unichi Noaki Satoshi Numazawa Joohyun jeon Shuntaro Kochi PTCAD-4 Part Process TCAD LabSamsung Device Solutions R&D JapanSamsung Japan Corporation2-7Sugasawa-choTsurumi-kuYokohama 230-0027Japan Computational Science&Engineering Team SAMSUNG ELECTRONICSHwaseong-siGyeonggi-do 18448Korea

We developed the Si/O/H reactive force field parameter set and applied to silicon dry/wet oxidation process to understand the underlying physics of the thermal oxidation of the Si(100)*** a systematic development of the Si/O parameter using the experimental data of the volumes of the SiO_(2) crystal as a reference,we reproduced the same result over the temperature range of 300–1300 *** strategic tunings of parameters related to Si/O/H system,we carried out the simulation comparing the wet-and dry processes.A significant acceleration of the oxide film growth seen in the‘in-situ-steam-generation(ISSG)’is successfully *** properties of our model imply its applicability in wider *** compare our results with those obtained by using parameter set recently developed by other *** the configuration of atoms near the interface of the SiO_(2) film,our model is found to be able to study the role of hydrogen atoms for the ISSG acceleration.

关键词： process acceleration film

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Monitored anesthesia care for craniotomy in a patient with Eisenmenger syndrome:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9859-9864页

作者： Hyun-Su Ri Younghoon jeon Department of Anesthesiology and Pain Medicine School of MedicineKyungpook National UniversityDaegu 41944South Korea Department of Anesthesiology and Pain Medicine School of DentistryKyungpook National UniversityDaegu 41944South Korea

BACKGROUND Eisenmenger syndrome(ES)is an uncorrected congenital cardiac defect with a left-to-right shunt,leading to pulmonary arterial *** with ES are susceptible to hemodynamic alterations during noncardiac surgery with general anesthesia,which increases perioperative morbidity and *** anesthesia care(MAC)is often used during minor procedures in patients with cardiac ***,few reports on MAC in patients with ES *** SUMMARY A 49-year-old man was admitted for a severe headache lasting 30 *** had been diagnosed with a large perimembranous ventricular septal defect(VSD)with bidirectional shunt flow and pulmonary arterial hypertension 10 years ago.A round mass in the right frontal lobe was revealed by Magnetic resonance *** aspiration using a neuronavigation system was performed under *** patient was stayed in the hospital for 5 d,and discharged without *** MAC may be effective for craniotomy in patients with ES.

关键词： Eisenmenger syndrome Pulmonary hypertension Sedation Anesthesia Craniotomy Case report

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Network-adaptive HD MPEG-2 video streaming with cross-layered channel monitoring in WLAN

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第5期7卷 885-893页

作者： PARK Sanghoon YOON hayoung KIM Jongwon Networked Media Laboratory Department of Information and Communications GwangJu Institute of Science and Technology Gwangju 500-712 Korea

In this paper, we propose a practical design and implementation of network-adaptive high definition (HD) MPEG-2 video streaming combined with cross-layered channel monitoring (CLM) over the IEEE 802.11a wireless local area network (WLAN). For wireless channel monitoring, we adopt a cross-layered approach, where an access point (AP) periodically measures lower layers such as medium access control (MAC) and physical (PHY) transmission information (e.g., MAC layer loss rate) and then sends the monitored information to the streaming server application. The adaptive streaming server with the CLM scheme reacts more quickly and efficiently to the fluctuating wireless channel than the end-to-end application-layer monitoring (E2EM) scheme. The streaming server dynamically performs priority-based frame dropping to adjust the sending rate according to the measured wireless channel condition. For this purpose, the proposed streaming system nicely provides frame-based prioritized packetization by using a real-time stream parsing module. Various evaluation results over an IEEE 802.11a WLAN testbed are provided to verify the intended Quality of Service (QoS) adaptation capability. Experimental results showed that the proposed system can mitigate the quality degradation of video streaming due to the fluctuations of time-varying channel.

关键词： Wireless video, Adaptive video streaming, Cross-layered design, Prioritized packetization, MPEG-2

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Fuzz-classification(p,l)-Angel:An enhanced hybrid artificial intelligence based fuzzy logic for multiple sensitive attributes against privacy breaches

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Digital Communications and Networks 2023年第5期9卷 1131-1140页

作者： Tehsin Kanwal Hasina Attaullah Adeel Anjum Abid Khan Gwanggil jeon Department of Computer Science COMSATS University IslamabadPakistan Department of Information Technology Quaid-e-Azam University IslamabadPakistan College of Science and Engineering School of Computing and MathsUniversity of DerbyDE221GBUK Department of Embedded Systems Engineering Incheon National UniversitySouth Korea

The inability of traditional privacy-preserving models to protect multiple datasets based on sensitive attributes has prompted researchers to propose models such as SLOMS,SLAMSA,(p,k)-Angelization,and(p,l)-Angelization,but these were found to be insufficient in terms of robust privacy and performance.(p,l)-Angelization was successful against different privacy disclosures,but it was not *** the best of our knowledge,no robust privacy model based on fuzzy logic has been proposed to protect the privacy of sensitive attributes with multiple *** this paper,we suggest an improved version of(p,l)-Angelization based on a hybrid AI approach and privacy-preserving approach like ***-classification(p,l)-Angel uses artificial intelligence based fuzzy logic for classification,a high-dimensional segmentation technique for segmenting quasi-identifiers and multiple sensitive *** demonstrate the feasibility of the proposed solution by modelling and analyzing privacy violations using High-Level Petri *** results of the experiment demonstrate that the proposed approach produces better results in terms of efficiency and utility.

关键词： Generalization Fuzzy-logic MSA Privacy disclosures Membership function (p,l)-Angelization QT HLPN

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