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Global existence and decay of solutions for the generalized bad Boussinesq equation

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Applied Mathematics(A Journal of Chinese Universities) 2013年第3期28卷 253-268页

作者： hatice Taskesen Necat Polat Abdulkadir Ertas Department of Statistics Yuzuncu Yil UniversityVan 65080 Turkey Department of Mathematics Dicle UniversityDiyarbakir 21280 Turkey

In this paper, we consider the global existence of solutions for the Cauchy problem of the generalized sixth order bad Boussinesq equation. Moreover, we show that the supremum norm of the solution decays algebraically to zero as （1 ＋ t）-（1/7） when t approaches to infinity, provided the initial data are sufficiently small and regular.

关键词： bad Boussinesq equation global existence asymptotic behavior oscillatory integral.

Protective Effects of Lycopene on Furan-treated Diabetic and Non-diabetic Rat Lung

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Biomedical and Environmental Sciences 2016年第2期29卷 143-147页

作者： hatice BAS Dilek PANDIR Bozok University Faculty of Arts and Science Department of Biology 66100 Yozgat Turkey

We assessed the effects of furan and lycopene on the histopathological and biochemical changes on lungs, body and lung weights, and food consumption of rats. Furan and diabetes caused histopathological changes, increment in malondialdehyde levels, and decrease in antioxidant enzyme activities. Lycopene showed a protective effect against these damages, except for glutathione-S-transferase and glutathione peroxidase activities. Consequently, furan and diabetes resulted in lung toxicity. Our findings demonstrate that furan treatment resulted in more alterations in histology and biochemical parameters in diabetic rats and lycopene showed protective effects against these alterations.

关键词： Protective Effects Lycopene Furan-treated Diabetic

COVID-19 infection in a kidney transplant recipient—special emphasis on pharmacokinetic interactions:A case report

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World Journal of Transplantation 2020年第11期10卷 365-371页

作者： Ebru Gok Oguz Kadir Gokhan Atilgan Sanem Guler Cimen hatice Sahin Tamer Selen Fatma AyerdenEbinc Sertac Cimen Mehmet deniz Ayli Department of Nephrology Diskapi Yildirim Beyazit Training and Res HospAnkara 6500Turkey Department of Nephrology Health Sciences UniversityAnkara 6500Turkey Department of General Surgery Diskapi Research and Training HospitalHealth Sciences UniversityAnkara 65000Select OneTurkey Department of Urology and Transplantation Health Sciences UniversityAnkara 65000Select OneTurkey Department of Nephrology and Transplantation Diskapi Yildirim Beyazit Teaching and Research HospitalAnkara 6500Turkey

BACKGROUND Solid organ transplant recipients are considered to be at high-risk of developing coronavirus disease 2019(COVID-19)-related *** optimal treatment for this patient group is ***,the treatment of COVID-19 in kidney transplant recipients should be determined individually,considering patient age and comorbidities,as well as graft function,time of transplant,and immunosuppressive *** treatments may give rise to severe *** the contrary,they may also lead to a milder and atypical presentation by diminishing the immune system *** SUMMARY A 50-year old female kidney transplant recipient presented to the transplant clinic with a progressive dry cough and fever that started three days *** the COVID-19 test was found to be negative,chest computed tomography images showed consolidation typical of the disease;thus,following hospital admission,anti-bacterial and COVID-19 treatments were ***,despite clinical improvement of the lung consolidation,her creatinine levels continued to *** of the graft showed no *** tacrolimus blood level was determined and the elevation in creatinine was found to be related to an interaction between tacrolimus and *** During the COVID-19 pandemic,various single or combination drugs have been utilized to find an effective treatment *** has increased the possibility of drug interactions.A limited number of studies published in the literature have highlighted some of these pharmacokinetic *** used for COVID-19 therapy;azithromycin,atazanavir,lopinavir/ritonavir,remdesivir,favipiravir,chloroquine,hydroxychloroquine,nitazoxanide,ribavirin,and tocilizumab,interact with immunosuppressive treatments,most importantly with calcineurin ***,their levels should be frequently monitored to prevent toxicity.

关键词： COVID-19 Kidney transplantation Drug interaction Pharmacokinetics Azithromycin Case report Calcineurin inhibitor

跨学科讲座中的元话语特性:深入解读EAP笔记的实质内涵

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Chinese Journal of Applied Linguistics 2024年第2期47卷 332-363,366页

作者：哈蒂斯·塞兹金埃切·泽希尔·托普卡亚塞尔柱克大学外国语学院土耳其恰纳卡莱马特大学英语教学系土耳其

学术讲座作为高等院校学生获取知识的主要途径之一,对学生而言具有不可或缺的重要性。为了确保学生能够充分吸收讲座内容,做笔记成为了一项至关重要的技能。事实上,记笔记的能力以及笔记的质量与学生的学习成绩之间存在着密切的关联。因... 详细信息

学术讲座作为高等院校学生获取知识的主要途径之一,对学生而言具有不可或缺的重要性。为了确保学生能够充分吸收讲座内容,做笔记成为了一项至关重要的技能。事实上,记笔记的能力以及笔记的质量与学生的学习成绩之间存在着密切的关联。因此,在EAP课程中,记笔记教学被视为一个不可或缺的组成部分,旨在培养学生良好的笔记习惯,从而助力他们取得更好的学术成绩。本研究旨在构建一个基于体裁的教学框架(Genre-Based Instruction,GBI),用于指导笔记教学的实践。为实现这一目标,本研究对八个跨学科讲座进行了深入分析。首先,我们依据Bouziri(2020)所建立的框架,对修辞功能进行了明确界定。随后,我们采纳了?del(2010)与Hyland(2005)共同提出的元话语框架,并据此确定了体现组织结构的元话语要素。经过深入研究,我们发现了修辞功能与元话语要素之间存在紧密的关联。也就是说,某些元话语项目可以作为使用某些修辞功能的信号。因此,记笔记的GBI框架是根据修辞功能与元话语要素之间的关联而构建的。

关键词：体裁跨学科学术讲座元话语笔记记录

Characterization of recuperating talent of white-rot fungi cells to dye-contaminated soil/water

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Chinese Journal of Chemical Engineering 2019年第3期27卷 634-638页

作者： Bugra Dayi Aidai Duishemambet Kyzy hatice Ardag Akdogan Pamukkale University Faculty of Science and Arts Department of Chemistry

This study was purposed to explore the decolorization of dyes by fungi on either a soil or in a liquid medium and to determine the application through batch shaking system. Two commercial dyes were decolorized and studied with four fungal strains in three media. Fungal growth is the best in malt extract/glucose medium for all organisms. Decolorization of reactive blue 220 and methyl red was investigated in soil medium by Trametes versicolor. These dyes were removed 91% and 80% for methyl red and reactive blue 220 respectively(dye concentration; 100 mg·L^(-1)) by both organisms. Enzymatic activities were monitored. Laccase(Lac) and manganese peroxidase(Mn P) were detected. MnP enzyme had important role for the dye decolorization. This study demonstrates that it is possible to decolorize some synthetic dyes, which would be highly advanced for dye containing wastewater and soil. These applications could be used for dye bioremediation.

关键词： Trametes versicolor Bioremediation Dye Contamination Soil Waste water

Modulation of brainstem reflexes induced by non-invasive brain stimulation: is there a future?

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Neural Regeneration Research 2021年第10期16卷 2004-2005页

作者： hatice Kumru Markus Kofler Josep Valls-Sole Institut Guttmann Institut Universitari de Neurorehabilitacióadscrit a la UAB089M6 Badalona–BarcelonaSpain Univ Autonoma de Barcelona 08M93 Bellaterra(Cerdanyola del Vallès)Spain FundacióInstitut d’Investigacióen Ciències de la Salut Germans Trias i Pujol BadalonaBarcelonaSpain Department of Neurology Hochzirl HospitalZirlAustria EMG Unit NeurologyHospital Clinic-IDIBAPSBarcelonaSpain

Kumru et al.(2019)have recently reported significant reduction of the R2 component of the trigeminal blink reflex following highfrequency(20 Hz)repetitive transcranial magnetic stimulation(rTMS)over the vertex in both,healthy subjects and in patients with spinal cord injury(SCI)(Figure 1).The modulatory influence of non-invasive brain stimulation(NIBS)on brainstem reflexes has been only scarcely studied.

关键词： stimulation brainstem al.

Non-invasive brain stimulation to promote motor and functional recovery following spinal cord injury

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Neural Regeneration Research 2017年第12期12卷 1933-1938页

作者： Aysegul Gunduz John Rothwell Joan Vidal hatice Kumru Department of Neurology Cerrahpasa School of Medicine Istanbul University Istanbul Turkey Sobell Department of Motor Neuroscience and Movement Disorders Institute of Neurology Queen Square University College London London UK Institut Guttmann Institut Universitari de Neurorehabilitaci6 adscrit a la UAB Badalona-Barcelona Spain Universidad Autonoma de Barcelona Bellaterra (Cerdanyola del Valles) Spain Fundacio Institut d'Investigacio en Ciencies de la Salut Germans Trias i Pujol Badalona Barcelona Spain

We conducted a systematic review of studies using non-invasive brain stimulation（NIBS： repetitive transcranial magnetic stimulation（r TMS） and transcranial direct current stimulation（t DCS）） as a research and clinical tool aimed at improving motor and functional recovery or spasticity in patients following spinal cord injury（SCI） under the assumption that if the residual corticospinal circuits could be stimulated appropriately, the changes might be accompanied by functional recovery or an improvement in spasticity. This review summarizes the literature on the changes induced by NIBS in the motor and functional recovery and spasticity control of the upper and lower extremities following SCI.

关键词： spinal cord injury non-invasive brain stimulation transcranial magnetic stimulation transcranialdirect current stimulation functional improvement spasticity neuropathic pain

Practical points that gastrointestinal fellows should know in management of COVID-19

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World Journal of Clinical Cases 2022年第16期10卷 5133-5145页

作者： Tevhide Sahin Cem Simsek hatice Yasemin Balaban Department of Gastroenterology Hacettepe UniversityFaculty of MedicineAnkara 06100Turkey

Pandemics obligate providers to transform their clinical *** extensive effort has been put to find out feasible approaches for gastrointestinal diseases and also to manage coronavirus disease 2019(COVID-19)related gastrointestinal ***,hepatitis,and pancreatitis can be seen in the COVID-19 *** procedures increase the risk of contamination for medical staff and patients despite precautions,therefore indications should be tailored to balance risks vs ***,whether the immunosupression in inflammatory bowel diseases,liver transplantation,and autoimmune liver diseases increases COVID-19 related risks and how to modify immunosupression are topics of ongoing *** review aims to provide most up to date practical approaches that a gastrointestinal fellow should be aware on the problems and management of gastrointestinal and hepatobiliary diseases during the COVID-19 pandemic.

关键词： COVID-19 Gastrointestinal diseases Practical points Endoscopy Gastrointestinal fellows

Hepatitis E virus: Epidemiology, diagnosis, clinical manifestations, and treatment

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World Journal of Gastroenterology 2020年第37期26卷 5543-5560页

作者： Abdullah Tarık Aslan hatice Yasemin Balaban Department of Internal Medicine Gölhisar State HospitalBurdur 15100Turkey Department of Gastroenterology Hacettepe University Faculty of MedicineAnkara 06100Turkey

The hepatitis E virus(HEV)is the fifth known form of viral hepatitis and was first recognized as the cause of an epidemic of unexplained acute hepatitis in the early ***,it is one of the most frequent causes of acute viral *** majority of HEV infections are asymptomatic and lead to the spontaneous clearance of the *** the eight different genotypes identified to date,HEV genotype 1(HEV1),HEV2,HEV3,and HEV4 are the most frequent genotypes causing infections in ***1 and HEV2 are prevalent in developing regions and able to result in large-scale outbreaks originating from contaminated water *** are also responsible for severe hepatitis in pregnant patients and *** contrast,HEV3 and HEV4 are zoonotic,and the transmission of these genotypes to humans occurs mainly through the fecal contamination of water and consumption of contaminated meat from infected *** main reservoir is the pig,and they are mostly encountered in developed *** major risk groups for HEV infection and its ensuing adverse consequences are pregnant women,infants,older people,immunocompromised individuals,patients with underlying chronic liver diseases,and workers that come into close contact with HEV-infected *** the clinical perspective,HEV infections have diverse clinical manifestations including acute and self-limiting hepatitis,acute-on-chronic liver disease,chronic hepatitis,cirrhosis,and liver *** HEV mainly results in acute selflimiting infection,chronic HEV infection may occur among immunocompromised patients(e.g.,solid-organ transplant recipients).Additionally,HEV-associated extrahepatic manifestations involving various organs have been reported in the last decade,although the causal link for many of them still needs to be *** and interferon-alpha are the most widely used agents for the treatment of HEV infections with a certain level of ***,ribavirin is contraindicated in pregnan

关键词： Hepatitis E Hepatitis E virus Extrahepatic manifestations Zoonotic infection Chronic hepatitis Acute hepatitis