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Epidemiological and clinical features of paediatric open globe injuries in southwestern Turkey

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International Journal of Ophthalmology(English edition) 2013年第6期6卷 855-860页

作者： hatice deniz ilhan Ahmet Burak Bilgin Ash Cetinkaya Mustafa Unal Iclal Yucel Department of Ophthalmology Akdeniz University

AIM:To evaluate the epidemiologic,anatomic,and clinical features of open globe injuries in ***:The medical files of patients under the age of 16 who had been operated for an open globe injury at Akdeniz University Hospital’s Department of Ophthalmology were retrospectively ***:A total of 90 patients were evaluated in this *** these patients,26(28.9%)were female and64(71.1%)were *** mean age of the patients was7.7±4.2 *** male/female ratio was observed to increase with increasing age(P=0.006,P=7.48).Injuries were most likely to occur in spring and autumn(P=0.028).The time interval between the injury and the surgical repair was 9.36±***(44.4%)of the injuries occurred in the home,27(30%)occurred in the yard,and 21(23.3%)happened while playing in the *** most common causes of injury were sharp metal objects(P<0.001).Injury to the cornea occurred in47(52.2%)of the patients(P<0.001).The most common complication to occur was cataract *** operations were necessary for 37(41.1%)of the *** final visual acuity was correlated with both the initial visual acuity of the wounded eye prior to surgery and the length of the wound(P<0.001,r=0.502 and P<0.001,r=-0.442,respectively).CONCLUSION:Open globe injuries that are suffered in childhood generally occur either at home,in the yard,or on the street,with sharp metal objects being the most common cause of *** initial visual acuity and the length of the wound are the most important determinants of the final visual acuity.

关键词： childhood epidemiology open globe injury prevention visual acuity

Evaluation of macular choroidal and microvascular network changes by activity scores and serum antibodies in thyroid eye patients and healthy subjects

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International Journal of Ophthalmology(English edition) 2023年第12期16卷 2089-2094页

作者： Mehmet Erkan Dogan Ibrahim Basol hatice deniz ilhan Yusuf Ayaz Olgar Ocal Department of Ophthalmology Akdeniz UniversityKonyaalti 07070AntalyaTurkey Department of Ophthalmology Kepez State HospitalAntalya 07320Turkey Department of Ophthalmology Suruc State HospitalSanliurfa 63800Turkey

AIM:To investigate the choroidal thickness and the microvascular network changes around the macula in thyroid eye disease(TED)patients at different stages and the relationship of those changes with risk factors,serum antibodies and the severity of ***:A total of 85 participants were *** participants underwent ophthalmology and endocrinology *** choroidal thickness(SFCT),superficial(s)and deep(d)foveal avascular zone(FAZ)area,mean(m)and central(c)superficial vascular density(SVD),deep vascular density(DVD)measurements of the enrolled cases were performed with Topcon swept source optical coherence tomography(OCT)/OCT angiography(OCTA)DRI OCT *** linear regression analysis was used to explore the associations between SFCT,FAZ area,SVD,DVD and the relevant factors of ***:Those with active TED patients had higher c-DVD and m-DVD levels(P<0.05),however there is no statistically significant difference in SFCT between active and stable TED *** the serum antibodies,it was observed that s-FAZ and d-FAZ increased,c-SVD and m-SVD decreased in patients with high thyroid stimulating hormone-receptor autoantibodies(TRAB)level,whereas SFCT thickened in patients with high levels of both TRAB and human thyroglobulin(hTG).There was no significant difference in SFCT,FAZ,SVD and DVD measurement at gender,between hyperthyroid and euthyroid patients and among those with or without thyroid papillary ***:The results show that both disease activation and serum antibodies differentially affect both superficial and deep retinal vascular *** has also been shown that high serum antibody levels affect choroidal thickness independent of clinical activity.

关键词： thyroid eye disease optic coherence tomography angiography vascular density choroidal thickness foveal avascular zone area

Magnetic resonance imaging evaluation of head and neck involvement in IgG4-related disease

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Asian Pacific Journal of Tropical Medicine 2023年第6期16卷 276-283页

作者： Umur Anil Pehlivan Kamil Karaali hatice deniz ilhan Mehmet Soy Didem Arslan Omer Kaya Rabia Miray Kisla-Ekinci Burcak Cakir-Pekoz Ummuhan Cay Arbil Acikalin Ahmet Muhtesem Agildere Department of Radiology Başkent University Adana Dr.Turgut Noyan Application and Research CenterAdanaTurkey Department of Radiology Akdeniz University Faculty of MedicineAntalyaTurkey Department of Ophthalmology Akdeniz University Faculty of MedicineAntalyaTurkey Department of Internal Medicine and Rheumatology Bahçelievler Medical ParkAltınbaşUniversity Faculty of MedicineİstanbulTurkey Department of Internal Medicine and Rheumatology Çukurova University Faculty of MedicineAdanaTurkey Department of Radiology Çukurova University Faculty of MedicineAdanaTurkey Department of Pediatric Rheumatology Adana City Training and Research HospitalAdanaTurkey Department of Radiology Adana City Training and Research HospitalAdanaTurkey Department of Pediatric Infectious Disease Çukurova University Faculty of MedicineAdanaTurkey Department of Pathology Çukurova University Faculty of MedicineAdanaTurkey Department of Radiology Başkent University Faculty of MedicineAnkaraTurkey

Objective:To evaluate the radiological features of IgG4-related disease(IgG4-RD)in the head and neck ***:In this radiology-based study,radiological features,clinical,laboratory,pathological findings,and prognosis of nine patients with head and neck involvement diagnosed with IgG4-RD were investigated ***:The median age of the patients was 38 years(range:2.5-79 years),and there were six males and three *** most common symptoms and clinical findings of the patients were eyelid and lacrimal gland swelling,painless exophthalmos,and *** most common site of involvement on MRI was the *** involvement was followed by branches of the trigeminal nerve,sinonasal cavity,cervical lymph nodes,and dural *** most common and remarkable imaging features were T2 hypointensity and diffuse homogeneous contrast ***:Head and neck involvement of the IgG4-RD,has specific imaging features that can help with ***,early diagnosis and better outcomes can be achieved with increasing awareness of these features of this relatively new pathology.

关键词： IgG4 Head and neck imaging Magnetic resonance imaging Orbit Perineural spreading

Qualitative behavior of discrete-time Caputo-Fabrizio logistic model with Allee effect

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International Journal of Biomathematics 2024年第4期17卷 217-234页

作者： hatice Karakaya Senol Kartal ilhan Oztirk Department of Mathematics Faculty of Science Erciyes UniversityKayseriTurkey Department of Science and Mathematics Education Faculty of Education Nevsehir Haci Bektas Veli University NevsehirTurkey Kapadokya University NevsehirTurkey

The aim of this paper is to investigate the dynamic behaviors of fractional-order logistic model with Allee effects in Caputo-Fabrizio *** of all,we apply the two-step Adams-Bashforth scheme to discretize the fractional-order logistic differential equation and obtain the two-dimensional discrete *** parametric conditions for local asymptotic stability of equilibrium points are obtained by Schur-Chon ***,we discuss the existence and direction for Neimark-Sacker bifurcations with the help of center manifold theorem and bifurcation *** simulations are provided to illustrate theoretical *** is observed that Allee effect plays an important role in stability *** Allee effect in population enhances the stability of the coexisting steady *** additional,the effect of fractional-order derivative on dynamic behavior of the system is also investigated.

关键词： Caputo-Fabrizio fractional derivative two-step Adams-Basforth method logistic differential equation Neimark-Sacker bifurcation Allee effect

Automated evaluation of parapapillary choroidal microvasculature in crowded optic discs:a controlled,optical coherence tomography angiography study

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International Journal of Ophthalmology(English edition) 2024年第1期17卷 113-118页

作者： hatice Arda Hidayet Sener Ozge Temizyurek hatice Kubra Sonmez Duygu Gulmez Sevim Cem Evereklioglu Fatih Horozoglu Ayse Busra Gunay Sener Department of Ophthalmology Erciyes University Medical FacultyKayseri 38090Turkey Department of Medical Informatics and Biostatistics Erciyes University Medical FacultyKayseri 38090Turkey

AIM:To compare superficial and deep vascular properties of optic discs between crowded discs and controls using optical coherence tomography angiography(OCT-A).METHODS:Thirty patients with crowded discs,and 47 control subjects were enrolled in the *** eye of each individual was included and OCT-A scans of optic discs were obtained in a 4.5×4.5 mm^(2) rectangular *** peripapillary capillary(RPC)density,peripapillary retinal nerve fiber layer(pRNFL)thickness,cup volume,rim area,disc area,cup-to-disc(c/d)area ratio,and vertical c/d ratio were obtained automatically using device *** parapapillary choroidal microvasculature(PPCMv)density was calculated using MATLAB *** the vertical c/d ratio of the optic disc was absent or small cup,it was considered as a crowded ***:The mean signal strength index of OCT-A images was similar between the crowded discs and control eyes(P=0.740).There was no difference in pRNFL between the two groups(P=0.102).There were no differences in RPC density in whole image(P=0.826)and peripapillary region(P=0.923),but inside disc RPC density was higher in crowded optic discs(P=0.003).The PPCMv density in the inner-hemisuperior region was also lower in crowded discs(P=0.026).The pRNFL thickness was positively correlated with peripapillary RPC density(r=0.498,P<0.001).The inside disc RPC density was negatively correlated with c/d area ratio(r=-0.341,P=0.002).CONCLUSION:The higher inside disc RPC density and lower inner-hemisuperior PPCMv density are found in eyes with crowded optic discs.

关键词： crowded optic disc ischemic optic neuropathy optical coherence tomography angiography parapapillary choroidal microvasculature

Vitamin D deficiency may predispose patients to increased risk of kidney transplant rejection

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World Journal of Transplantation 2022年第9期12卷 299-309页

作者： Semih Buyukdemirci Ebru Gok Oguz Sanem Guler Cimen hatice Sahin Sertac Cimen Mehmet deniz Ayli Department of Internal Medicine Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of Nephrology Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of General Surgery Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of Urology Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey

BACKGROUND Vitamin D deficiency occurs in more than 80%of kidney transplant *** immunomodulatory effects can predispose transplant recipients to rejection and chronic allograft nephropathy(CAN).This study determined the association between serum 25(OH)vitamin D,biopsy-proven allograft rejection,and CAN *** To determine the relationship between serum 25(OH)vitamin D level and biopsy-proven allograft rejection and CAN rate in renal transplant *** Adult renal transplant recipients followed at the clinic between January 2013 and 2018 were *** requiring graft biopsy due to declined function,hematuria,and proteinuria were *** two groups were compared regarding collected data,including the biopsy results,immunologic parameters,vitamin D,parathyroid hormone(PTH),phosphorus,albumin levels,and graft function *** Fifty-two recipients who underwent graft biopsy met the inclusion *** all,14 recipients had a vitamin D level>15 ng/mL(group 1)vs≤15 ng/mL(group 2)in *** total,27 patients had biopsy-proven rejection,and 19 had *** was only 1 recipient with biopsyproven rejection in group 1,whereas there were 24 patients with rejection in group *** rejection rate was significantly higher in group 2 than in group 1(P<0.001).Four patients were diagnosed with CAN in group 1 vs fifteen in group *** was no significant difference in the CAN rate between the two *** was higher at the time of graft biopsy(P=0.009,P=0.022)in group 1 with a mean of 268 pg/***-specific antibodies were detected in 14(56.0%)of the recipients with *** D level was 9.7±3.4 ng/mL in the rejection group vs 14.7±7.2 in the non-rejection group;this difference was statistically significant(P=0.003).The albumin levels were significantly lower in patients with rejection than in those without rejection(P=0.001).In univariate regression analysis of risk factors affecting rejection,sex,serum vitamin D,phosphorus a

关键词： Kidney transplantation Rejection 25(OH)vitamin D Vitamin D Chronic allograft nephropathy

Benthic foraminiferal assemblages from the Safranbolu Formation(Cuisian,Eocene),Northwest Anatolia,Turkey

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Journal of Palaeogeography 2020年第1期9卷 21-41页

作者： Kubra Okur hatice Kutluk Department of Geology Eskisehir Osmangazi UniversityBati Meselik26480 EskisehirTurkey

Twenty-one outcrop samples collected from a 28-m-thick section from the Safranbolu Formation of the southwestern part of the Safranbolu Basin,Anatolia,Turkey yielded well-preserved benthic foraminifera belonging mainly to the genera Alveolina,Nummulites,Assilina,Rotalia,Disclocyclina and *** is the most diversified genus that is represented by sixteen species:Alveolina archiaci,***,***,***,***,***,***,***,***,***,***,*** gueroli,***,***,*** and *** safranboluensis and *** are described *** of the fossil assemblage with those assemblages previously reported from both Turkey and other Tethyan sub-basins revealed that the deposition occurred during the Cuisian(Eocene)and corresponded to Shallow Benthic Foraminiferal Zones(SBFZ)10–*** abundance and diversity of the larger benthic foraminifera indicated that the Safranbolu Formation was deposited under transgressive conditions.

关键词： Eocene Cuisian Safranbolu Formation Benthic foraminifera Alveolina Northwest Anatolia

Pollen Morphology of Acinos Miller Species Growing in Turkey

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Journal of Integrative Plant Biology 2007年第9期49卷 1386-1392页

作者： Ayla Kaya hatice Kutluk Anadolu University Faculty of PharmacyDepartment of Pharmaceutical BotanyEskisehir 26470 Turkey Osmangazi University Department of Geology (Paleobotany)Bati Meselik Eskisehir 26040 Turkey

The pollen morphology of six taxa of the genus Acinos Miller has been examined under scanning electron microscopy （SEM） and a description of each taxon has been given. Acinos pollen is stephanocolpate （hexacolpate）. Two main exine sculpturing types, foveolate-reticulate （only in subspecies of A. troodi） and reticulate have been defined. The dimension for the polar length ranges between 25.8-47.4 μm, equatorial width 24.5-34.4μm, colpus length 20.0-40.5μm and colpus width 1.2-2.5 μm. The shape is mostly subprolate to prolate, seldomly prolate-spheroidal. The results reveal rather uniform morphological features, however fine details are characteristic to differentiate the pollen taxa. Acinos pollen also share some common morphological features with the other Lamiaceae pollen.

关键词： Acinos Lamiaceae morphology polen scanning electron microscopy.

Efects of Die Corner Radius and Temperature on the Formability of AA7075-T6 Alloy

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Acta Metallurgica Sinica(English Letters) 2013年第5期26卷 623-629页

作者： hatice Evlen brahim Kad Mustafa Ya sar Technology Faculty Karabuk University

This study focused on the formability of aluminium alloy（7075-T6） sheets through hydroforming route. Formability of these sheets was tested using a warm forming setup at three diferent temperatures and four diferent die corner radii. Forming limit diagrams（FLD） were generated by measuring the grids of the sheet formed. The results show that the forming limit of AA7075-T6 can be significantly improved when the blank was heated to 140–250℃. It was also observed that as the temperature increases above 140℃, dome height began to decrease. Also the results indicated that both the die corner radius and temperature have a significant efect on the stress-strain curve and warm forming of AA7075-T6 sheets. Thus, with the temperature increased from room temperature（RT） to 140℃, the flow stress decreased and the strain increased, hence, the formability is enhanced. However, further increase in temperature causes decreases the flow stress and strain. Similar changes of the flow curve were seen in die corner radius. Decreasing the die corner radius decreases the flow stress and increase the strain. Moreover, an equation was obtained by establishing correlations between the experimental parameters and their results. In this way, it became possible to make predictions.

关键词： Al-Zn-Mg-Cu Alloy Drawing process Formability Forming limit curve Deformation