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COVID-19 vaccine hesitancy and related factors among primary healthcare workers in a district of Istanbul:a cross-sectional study from Turkey

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Family Medicine and Community Health 2022年第2期10卷 32-39页

作者： haticeİkiışık Mehmet Akif Sezerol Yusuf Taşçı Işıl Maral Department of Public Health Faculty of MedicineIstanbul Medeniyet UniversityIstanbulTurkey Public Health Department Institute of Health SciencesIstanbul UniversityIstanbulTurkey

Objectives This study aimed to determine the COVID-19 risk perceptions,vaccination intentions and predictive factors of family physicians and family healthcare staff working in primary care inÜskü*** A cross-sectional study was performed using an online questionnaire to determine the demographic and general characteristics of the participants and their willingness to be *** An online questionnaire was applied to family physicians and family health workers working in primary care family health centres inÜsküdar between 25 and 29 December *** analysis was performed to identify independent predictors of the willingness of individuals to be *** Out of 323 health workers working in 44 family health centres in the district,a total of 276 health workers were reached,including 126 physicians(n=158,79.7%)and 150 midwives/nurses(n=165,90.9%)(response rate 85.4%).Results 50.4%(n=139)of the healthcare workers were willing to have the COVID-19 vaccine,29%(n=80)were undecided and 20.7%(n=57)refused the *** rate of acceptance to be vaccinated was higher in physicians,in men and in those who had not received a seasonal influenza vaccination regularly each *** Half of the primary healthcare workers,one of the high-risk groups in the pandemic,were hesitant or refused to be vaccinated for *** the factors affecting the vaccine acceptance rates of healthcare professionals can be considered one of the most strategic moves in reaching the target of high community vaccination *** evidence-based planning in vaccination studies,there is a need to investigate the reasons for COVID-19 vaccine acceptance by healthcare workers at all levels.

关键词： nurse workers district

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Etiology of granulomatous inflammation:A retrospective study of 174 children in a tertiary care center

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Asian Pacific Journal of Tropical Medicine 2022年第11期15卷 511-517页

作者： Ummühan Cay Derya Alabaz ÖzlemÖzgür Gündeşlioğlu Aysun hatice Uguz Hande Yanar Department of Pediatric Infectious Diseases Faculty of MedicineÇukurova UniversityAdanaTurkey Department of Pathology Faculty of MedicineÇukurova UniversityAdanaTurkey

Objective:To investigate granulomatous inflammation etiology based on clinical history and ancillary ***:Children aged<18 years with biopsy proven granulomatous lesions in any tissue specimens between January 2014 and January 2022 were included in the *** diagnosis was based on the results of immunohistochemical staining,molecular tests,culture,serology,radiological and other auxiliary laboratory *** were categorized into infectious and noninfectious ***:In total,174 patients with granulomatosis inflammation confirmed by histopathology were *** 59.2%patients were males,and the median age was 4.48(IQR 2.36-6.39)years(range:16 months-18 years).The tissues/organs that were most commonly biopsied were lymph node,bone,skin,and lung(51.1%,17.8%,9.2%,and 5.7%,respectively).Infectious and non-infectious causes were identified in 73.0%and 12.6%patients,respectively,in terms of granulomatosis inflammation etiology;however,no cause was identified in 14.4%*** most common infectious cause was tuberculosis(in 51.7%patients),followed by toxoplasmosis,aspergillosis,mucormycosis,leishmaniasis,and cat-scratch disease(in 8.6%,5.7%,1.7%,1.7%,and 1.1%patients,respectively).The common non-infectious cause was chronic granulomatous *** evaluation revealed granulomatosis inflammation in 33.3%patients,necrotizing granulomatosis inflammation in 30.5%patients,and caseating granulomatosis inflammation in 12.1%*** the pathology results of patients with and without tuberculosis were compared,the incidence of caseating granulomatosis inflammation(P=0.003)and necrotizing granulomatosis inflammation(P=0.005)was higher in patients with ***:Chronic granulomatous disease is the most common non-infectious cause in ***,primary or secondary immune deficiencies may cause granulomatosis inflammation,especially in pediatric patients.

关键词： Granulomatous Children Tuberculosis Chronic granulomatous disease

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Benthic foraminiferal assemblages from the Safranbolu Formation(Cuisian,Eocene),Northwest Anatolia,Turkey

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Journal of Palaeogeography 2020年第1期9卷 21-41页

作者： Kubra Okur hatice Kutluk Department of Geology Eskisehir Osmangazi UniversityBati Meselik26480 EskisehirTurkey

Twenty-one outcrop samples collected from a 28-m-thick section from the Safranbolu Formation of the southwestern part of the Safranbolu Basin,Anatolia,Turkey yielded well-preserved benthic foraminifera belonging mainly to the genera Alveolina,Nummulites,Assilina,Rotalia,Disclocyclina and *** is the most diversified genus that is represented by sixteen species:Alveolina archiaci,***,***,***,***,***,***,***,***,***,***,*** gueroli,***,***,*** and *** safranboluensis and *** are described *** of the fossil assemblage with those assemblages previously reported from both Turkey and other Tethyan sub-basins revealed that the deposition occurred during the Cuisian(Eocene)and corresponded to Shallow Benthic Foraminiferal Zones(SBFZ)10–*** abundance and diversity of the larger benthic foraminifera indicated that the Safranbolu Formation was deposited under transgressive conditions.

关键词： Eocene Cuisian Safranbolu Formation Benthic foraminifera Alveolina Northwest Anatolia

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Pollen Morphology of Acinos Miller Species Growing in Turkey

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Journal of Integrative Plant Biology 2007年第9期49卷 1386-1392页

作者： Ayla Kaya hatice Kutluk Anadolu University Faculty of PharmacyDepartment of Pharmaceutical BotanyEskisehir 26470 Turkey Osmangazi University Department of Geology (Paleobotany)Bati Meselik Eskisehir 26040 Turkey

The pollen morphology of six taxa of the genus Acinos Miller has been examined under scanning electron microscopy （SEM） and a description of each taxon has been given. Acinos pollen is stephanocolpate （hexacolpate）. Two main exine sculpturing types, foveolate-reticulate （only in subspecies of A. troodi） and reticulate have been defined. The dimension for the polar length ranges between 25.8-47.4 μm, equatorial width 24.5-34.4μm, colpus length 20.0-40.5μm and colpus width 1.2-2.5 μm. The shape is mostly subprolate to prolate, seldomly prolate-spheroidal. The results reveal rather uniform morphological features, however fine details are characteristic to differentiate the pollen taxa. Acinos pollen also share some common morphological features with the other Lamiaceae pollen.

关键词： Acinos Lamiaceae morphology polen scanning electron microscopy.

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Structural performance of authentic architectural heritage designs:A masonry monument in Western Anatolia

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Frontiers of Architectural Research 2023年第6期12卷 1212-1233页

作者： hatice Ayşegül Demir Mine Hamamcıoğlu-Turan Kutay Yücetürk Engin Aktaş Department of Conservation and Restoration of Cultural Heritage İzmir Institute of Technologyİzmir 35433Turkey Department of Civil Engineering İzmir Institute of Technologyİzmir 35433Turkey

The aim of the study is to present a multi-leveled comparative evaluation approach for structural characteristics of historic masonry monuments so that the consciousness in their authentic designs is comprehended,and the optimum structural performance is clarified.A case study approach is preferred by the examination of the Bedesten(15th‒16th centuries)located in Bergama,_Izmir,*** structure is documented through tacheometric *** construction techniques of structural elements are *** documented qualities are compared with similar period and/or function structures in order to rank the frequency of construction *** geometrical factor of safety state is defined theoretically for domes and *** element macro model of the Bedesten is generated in ANSYS software and overall structural analysis of the structure is made to evaluate the safety level of historic building by the limit states through self-weight *** presented study shows that the rare structural characteristics can both contribute to structural safety and cause ***,total consciousness in structural design cannot be stated for the studied Bedesten,but the structural designs that are often preferred in the monuments built at the same period in the proximity to each other have low vulnerability,yielding to conscious preferences.

关键词： Construction techniques Architectural heritage Structural theory of masonry Numerical analysis Bergama Bedesten

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Efects of Die Corner Radius and Temperature on the Formability of AA7075-T6 Alloy

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Acta Metallurgica Sinica(English Letters) 2013年第5期26卷 623-629页

作者： hatice Evlen brahim Kad Mustafa Ya sar Technology Faculty Karabuk University

This study focused on the formability of aluminium alloy（7075-T6） sheets through hydroforming route. Formability of these sheets was tested using a warm forming setup at three diferent temperatures and four diferent die corner radii. Forming limit diagrams（FLD） were generated by measuring the grids of the sheet formed. The results show that the forming limit of AA7075-T6 can be significantly improved when the blank was heated to 140–250℃. It was also observed that as the temperature increases above 140℃, dome height began to decrease. Also the results indicated that both the die corner radius and temperature have a significant efect on the stress-strain curve and warm forming of AA7075-T6 sheets. Thus, with the temperature increased from room temperature（RT） to 140℃, the flow stress decreased and the strain increased, hence, the formability is enhanced. However, further increase in temperature causes decreases the flow stress and strain. Similar changes of the flow curve were seen in die corner radius. Decreasing the die corner radius decreases the flow stress and increase the strain. Moreover, an equation was obtained by establishing correlations between the experimental parameters and their results. In this way, it became possible to make predictions.

关键词： Al-Zn-Mg-Cu Alloy Drawing process Formability Forming limit curve Deformation

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Global existence and decay of solutions for the generalized bad Boussinesq equation

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Applied Mathematics(A Journal of Chinese Universities) 2013年第3期28卷 253-268页

作者： hatice Taskesen Necat Polat Abdulkadir Ertas Department of Statistics Yuzuncu Yil UniversityVan 65080 Turkey Department of Mathematics Dicle UniversityDiyarbakir 21280 Turkey

In this paper, we consider the global existence of solutions for the Cauchy problem of the generalized sixth order bad Boussinesq equation. Moreover, we show that the supremum norm of the solution decays algebraically to zero as （1 ＋ t）-（1/7） when t approaches to infinity, provided the initial data are sufficiently small and regular.

关键词： bad Boussinesq equation global existence asymptotic behavior oscillatory integral.

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Vitamin D deficiency may predispose patients to increased risk of kidney transplant rejection

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World Journal of Transplantation 2022年第9期12卷 299-309页

作者： Semih Buyukdemirci Ebru Gok Oguz Sanem Guler Cimen hatice Sahin Sertac Cimen Mehmet Deniz Ayli Department of Internal Medicine Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of Nephrology Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of General Surgery Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey Department of Urology Sağlık Bilimleri UniversitesiAnkara 65000AltındağTurkey

BACKGROUND Vitamin D deficiency occurs in more than 80%of kidney transplant *** immunomodulatory effects can predispose transplant recipients to rejection and chronic allograft nephropathy(CAN).This study determined the association between serum 25(OH)vitamin D,biopsy-proven allograft rejection,and CAN *** To determine the relationship between serum 25(OH)vitamin D level and biopsy-proven allograft rejection and CAN rate in renal transplant *** Adult renal transplant recipients followed at the clinic between January 2013 and 2018 were *** requiring graft biopsy due to declined function,hematuria,and proteinuria were *** two groups were compared regarding collected data,including the biopsy results,immunologic parameters,vitamin D,parathyroid hormone(PTH),phosphorus,albumin levels,and graft function *** Fifty-two recipients who underwent graft biopsy met the inclusion *** all,14 recipients had a vitamin D level>15 ng/mL(group 1)vs≤15 ng/mL(group 2)in *** total,27 patients had biopsy-proven rejection,and 19 had *** was only 1 recipient with biopsyproven rejection in group 1,whereas there were 24 patients with rejection in group *** rejection rate was significantly higher in group 2 than in group 1(P<0.001).Four patients were diagnosed with CAN in group 1 vs fifteen in group *** was no significant difference in the CAN rate between the two *** was higher at the time of graft biopsy(P=0.009,P=0.022)in group 1 with a mean of 268 pg/***-specific antibodies were detected in 14(56.0%)of the recipients with *** D level was 9.7±3.4 ng/mL in the rejection group vs 14.7±7.2 in the non-rejection group;this difference was statistically significant(P=0.003).The albumin levels were significantly lower in patients with rejection than in those without rejection(P=0.001).In univariate regression analysis of risk factors affecting rejection,sex,serum vitamin D,phosphorus a

关键词： Kidney transplantation Rejection 25(OH)vitamin D Vitamin D Chronic allograft nephropathy

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Clinical and genetic characteristics of retinoblastoma patients in a single center with four novel RB1 variants

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International Journal of Ophthalmology(English edition) 2023年第8期16卷 1274-1279页

作者： Özge Vural hatice Tuba Atalay Gulsum Kayhan Bercin Tarlan Merve Oral Arzu Okur Faruk GüçlüPınarlı Ceyda Karadeniz Department of Pediatric Hematology and Oncology Gazi University Faculty of MedicineAnkara 06500Türkiye Department of Ophthalmology Gazi University Faculty of MedicineAnkara 06500Türkiye Department of Medical Genetics Gazi University Faculty of MedicineAnkara 06500Türkiye

AIM:To assess the clinical and genetic characteristics of children diagnosed with retinoblastoma(RB)at Gazi University Faculty of Medicine’s Department of Pediatric ***:All cases diagnosed with RB and received treatment and follow-up in the Ophthalmology and Pediatric Oncology Department,October 2016 to May 2021 were evaluated *** RB1 gene was analyzed by next-generation sequencing(NGS)technique in DNAs obtained from peripheral blood samples of the ***:This study included 53 cases with 67 RBaffected eyes during the study *** mean age was 24.6(median:18.5,range:3–151)*** were 15(22.3%)Group D eyes and 39(58.2%)Group E *** RB1 gene was sequenced by the NGS method in 19 *** RB1:NM_000321.3:c.54_76del(***19AlafsTer4)variant was detected in a 15-month-old female with bilateral *** RB1:NM_000321.3:c.1814+3A>T variant was detected in a 5.5-month-old male with bilateral *** intronic RB1:NM_000321.3:c.1332+4A>G variant was detected in patient 14,a 13-month-old male with unilateral *** RB1:NM_000321.3:c.575_576del(***192SerfsTer10)variant was found in an 18-month-old female with an allele frequency of 37%.These variants have not been reported in the literature and mutation ***:Four novel variants are described and one of them is found in two different *** data is crucial for assessing *** serves as a guide for estimating the long-term risk of secondary malignancy as well as the short-term risk of developing additional malignancies in the same eye and the other eye.

关键词： retinoblastoma RB1 novel mutations next generation sequencing

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Protective Effects of Lycopene on Furan-treated Diabetic and Non-diabetic Rat Lung

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Biomedical and Environmental Sciences 2016年第2期29卷 143-147页

作者： hatice BAS Dilek PANDIR Bozok University Faculty of Arts and Science Department of Biology 66100 Yozgat Turkey

We assessed the effects of furan and lycopene on the histopathological and biochemical changes on lungs, body and lung weights, and food consumption of rats. Furan and diabetes caused histopathological changes, increment in malondialdehyde levels, and decrease in antioxidant enzyme activities. Lycopene showed a protective effect against these damages, except for glutathione-S-transferase and glutathione peroxidase activities. Consequently, furan and diabetes resulted in lung toxicity. Our findings demonstrate that furan treatment resulted in more alterations in histology and biochemical parameters in diabetic rats and lycopene showed protective effects against these alterations.

关键词： Protective Effects Lycopene Furan-treated Diabetic

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