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Prevalence and characteristics of gallstone disease in an Iranian population:a study on cadavers

Hepatobiliary & Pancreatic Diseases International 2007年第5期6卷 509-512页

作者： Esmaail Farzaneh hassan tofighi zavvareh Jaber Gharadaghi Mehrdad Sheikhvatan Legal Medicine Tehran Legal Medicine CenterMedical Sciences/Tehran UniversityTehranIran Medical Sciences/University ofTehran TehranIran

BACKGROUND:The prevalence of gallstones is low in *** Iran,many factors influence the prevalence of this *** aim of this study was to determine the prevalence of gallbladder stones and their chemical characteristics in a population by the study of cadavers. METHODS:In this cross-sectional study,autopsies were performed on 253 cadavers of more than 13 years *** cadavers were studied to determine the number,location of stone formation,chemical composition,dry weight,and mean diameter of stones in the gallbladder and common bile duct. RESULTS:The prevalence of gallstone disease in these cadavers was 6.3%(men 4.7%,women 8.6%,not significantly different,P=0.216).There was a positive relationship between the age and prevalence of gallstone disease(P=0.033).The most common stone compositions were cholesterol and *** mean diameter (P=0.0058)and dry weight(P<0.0001)of stones were higher in the gallbladder than in the common bile duct. Positive relations between the amount of oxalate and mean diameter,and between the amount of oxalate and mean dry weight of gallstones were found,but the relationship between the amount of cholesterol and mean diameter was inverse. CONCLUSIONS:The prevalence of gallstones differed among age *** and dry weight of gallstones were dependent on location of stone formation and chemical composition.

关键词： gallstone gallbladder common bile duct prevalence cadavers

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