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红花籽粕对小鼠的急性毒性及抗溃疡性结肠炎作用研究

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中草药 2024年第8期55卷 2601-2610页

作者：戚曼王文萱付向磊姜超张亮 MD hasan ALI 李剑楚生辉刘敏石河子大学药学院新疆植物药资源利用教育部重点实验室新疆石河子832003 华东理工大学药学院生物反应器工程国家重点实验室上海200000

目的评价红花籽粕(红花Carthamus tinctorius的种子经过压榨提取红花籽油后的副产品)对小鼠的急性毒性及抗溃疡性结肠炎(ulcerative colitis,UC)作用。方法C57BL/6小鼠ig不同剂量的红花籽粕,7 d后计算脏器指数,采用苏木素-伊红(HE)染色... 详细信息

目的评价红花籽粕(红花Carthamus tinctorius的种子经过压榨提取红花籽油后的副产品)对小鼠的急性毒性及抗溃疡性结肠炎(ulcerative colitis,UC)作用。方法C57BL/6小鼠ig不同剂量的红花籽粕,7 d后计算脏器指数,采用苏木素-伊红(HE)染色观察肝、脾、肾组织病理变化,测定血清中肝功能、肾功能及血脂水平,以评价红花籽粕的急性毒性。建立葡聚糖硫酸钠(dextran sulphate sodium,DSS)诱导的UC小鼠模型,每天记录小鼠体质量,测定疾病活动指数(disease activity index,DAI)评分、结肠长度以及脏器指数,采用HE染色和阿利新蓝-过碘酸雪夫(AB-PAS)染色评价结肠组织病理学变化,采用qRT-PCR和Western blotting检测结肠组织中炎症和黏膜屏障相关因子表达。结果急性毒性实验中,与对照组比较,红花籽粕组小鼠脏器指数、血液生化指标没有显著差异,脏器病理切片也未见异常。红花籽粕对DSS诱导的UC小鼠具有较好的保护作用,可以显著改善体质量减轻、DAI评分升高、结肠长度缩短等临床症状(P<0.01),减轻结肠组织病理损伤,抑制肠道炎症细胞的浸润,保护杯状细胞,提高紧密连接蛋白和黏蛋白的表达(P<0.05、0.01、0.001),改善肠道屏障完整性。结论红花籽粕具有较高的安全性,且对DSS诱导的UC小鼠具有显著的治疗作用。

关键词：红花籽粕急性毒性溃疡性结肠炎炎症肠道屏障

Ensuring Security and Privacy in the Internet of Things: Challenges and Solutions

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Journal of Computer and Communications 2024年第8期12卷 257-277页

作者： Nur Mohammad Rabeya Khatoon Sadia Islam Nilima Jahanara Akter Md Kamruzzaman hasan Mahmud Sozib Department of Information Technology Westcliff University 17877 Von Karman Ave 4th Floor Irvine CA 92614 United States Department of Business Administration International American University 3440 Wilshire Blvd STE 1000 Los Angeles CA 90010 United States Department of Business Administration Westcliff University 17877 Von Karman Ave 4th Floor Irvine CA 92614 United States School of Business & Economics North South University Dhaka Bangladesh

The Internet of Things (IoT) represents a revolutionary paradigm, enabling a vast array of devices to be ubiquitously interconnected via the Internet, thereby facilitating remote control and management of these devices. This pervasive integration into daily life brings significant convenience but also raises substantial concerns regarding the security of personal data collected and stored online. As the number of connected devices grows, the urgency to address privacy and security issues becomes paramount. IoT systems are particularly susceptible to threats that could compromise consumer privacy and security, affecting their practical deployment. Recent research efforts have focused on enhancing the security of IoT devices, including the exploration of blockchain technologies to mitigate these concerns. This paper aims to elucidate the security and privacy challenges inherent in IoT systems by examining vulnerabilities at each layer of the IoT protocol stack. It identifies key security requirements and reviews existing solutions designed to protect IoT systems from a layered perspective, thereby providing a comprehensive overview of the current landscape of IoT security and highlighting the critical need for robust security measures as the adoption of IoT continues to expand.

关键词： IoT Security Privacy Blockchain Technologies Layered Perspective

Optimizing Resource Management for IoT Devices in Constrained Environments

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Journal of Computer and Communications 2024年第8期12卷 81-98页

作者： Sadia Islam Nilima Md Khokan Bhuyan Md Kamruzzaman Jahanara Akter Rakibul hasan Fatema Tuz Johora Department of Business Administration International American University 3440 Wilshire Blvd STE 1000 Los Angeles CA 90010 United States Department of Business Administration Westcliff University 17877 Von Karman Ave 4th Floor Irvine CA 92614 United States

Embedded computing device implementation on the Internet of Things (IoT) requires careful assessment of their intrinsic resource limitations. These constraints are not limited to memory and processing capabilities but extend to the network interfaces, particularly due to the low-power radio standards that these devices typically employ. The IPv6 protocol is shown to be a strong option for guaranteeing interoperability in the IoT, mostly because of its large address space, the range of current IP-based protocols, and its intrinsic versatility. Considering these benefits, we investigate if current IP-based network management protocols can be implemented on devices with limited resources. We investigate the resource needs in particular for implementing Network Configuration Protocol (NETCONF) and Simple Network Management Protocol (SNMP) on an 8-bit AVR-based device. Our investigation reveals the specific memory and processing demands of these protocols, providing valuable insights into their practicality and efficiency in constrained IoT environments. This study underscores the potential and challenges of leveraging IPv6-based network management protocols to enhance the functionality and interoperability of IoT devices while operating within stringent resource limitations.

关键词： Internet of Things Resource Constraint IPv6 Protocol IP-Based Network Management Network Management Protocol Network Configuration Protocol

Unsheltered: Navigating California’s Homelessness Crisis

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Sociology Study 2024年第3期14卷 143-156页

作者： Rakibul hasan Md Abdullah Al Mahmud Sayeda Farjana Farabi Jahanara Akter Fatema Tuz Johora Westcliff University CaliforniaUSA International American University CaliforniaUSA

This paper presents a comprehensive exploration of the complex phenomenon of homelessness in California,with a specific focus on the state’s three largest cities-Los Angeles,San Francisco,and San *** the backdrop of a high cost of living and a housing market strained by insufficient affordable options,the multifaceted nature of social diversity further complicates the landscape,leading to a widespread presence of homelessness that spans both major urban centers and rural *** an in-depth examination of the distinct challenges confronting each city,ranging from housing shortages to intricate social dynamics,this study seeks to illuminate the underlying factors driving homelessness and identify potential avenues for ***,the paper delves into the unique vulnerabilities experienced by certain demographics within the homeless population,including veterans,families with children,and LGBTQ+individuals,highlighting the critical need for targeted solutions tailored to their specific *** synthesizing existing research and incorporating firsthand accounts,this research endeavor aims to contribute to a deeper understanding of homelessness in California and inform the development of comprehensive strategies aimed at fostering inclusive,sustainable communities statewide.

关键词： homeless California veterans children LGBTQ

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Clinical Complementary Medicine and Pharmacology 2024年第1期4卷 85-94页

作者： Iffat Ara Rita Turcio Tasmia Islam Md.Sabbir Hossain Md.Kamrul hasan Department of Biochemistry and Molecular Biology Tejgaon CollegeNational UniversityGazipur-1700Bangladesh Department of Pharmacy University of Naples Federico IIvia Domenico Montesano49-80131 Napoli NAItaly Department of Genetic Engineering and Biotechnology Jashore University of Science and TechnologyJashore-7408Bangladesh Department of Public Health North South UniversityDhaka-1229Bangladesh

Background:Licochalcone A(LCA)is a flavonoid derived from the roots of Glycyrrhiza uralensis *** DC and other related *** natural source has been extensively used in complementary medicine,especially traditional Chinese medicine,to treat various *** as a phenolic chalcone compound,LCA has gained significant attention in recent years due to its various pharmacological ***:The objective of this review article is to assess the anti-aging ralated pharmacological properties of ***:An exhaustive search of several scientific databases was conducted using various relevant keywords to write this review article on LCA,focusing on its therapeutic applications and anti-aging-related pharmacological *** inclusion and exclusion criteria were strictly followed to retrieve updated relevant ***:A collection of 292 papers were screened,and 131 were included in this review for an in-depth analysis of Licochalcone A,focusing on its anti-aging-related pharmacological activities and relevant mechanisms,and its toxicity and side ***,the potential of LCA as a pharmacological product is discussed,emphasizing its health benefits and potential as a pharmaceutical ***:These findings indicate that Licochalcone A is a promising natural therapeutic agent for anti-aging therapy and other ailments.

关键词： Licochalcone A Glycyrrhiza uralensis Chalcone Anti-aging Neuroprotective Antioxidant Skin protection Therapeutic agent

PET微塑料水解再造缺陷铁基金属有机框架及其应用研究

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中国环境科学 2024年第9期44卷 5222-5233页

作者：蒋文斌姜晨晨韦选香徐李聪王姗丽 hasan MD Shahib 吴明华余德游浙江理工大学纺织科学与工程学院(国际丝绸学院) 浙江理工大学生态染整技术教育部工程研究中心浙江杭州310018 浙江理工大学桐乡研究院有限公司浙江桐乡314500

为了有效去除聚对苯二甲酸乙二酯(PET)微塑料,采用碱性水解方法将PET微塑料升级再造,制备缺陷铁基金属有机框架(Fe-MOFs)催化剂,用于催化臭氧深度处理模拟印染废水.结果表明,在Na OH浓度为2mol/L、水解温度120℃、水解时间120min的条件... 详细信息

为了有效去除聚对苯二甲酸乙二酯(PET)微塑料,采用碱性水解方法将PET微塑料升级再造,制备缺陷铁基金属有机框架(Fe-MOFs)催化剂,用于催化臭氧深度处理模拟印染废水.结果表明,在Na OH浓度为2mol/L、水解温度120℃、水解时间120min的条件下,PET微塑料去除率达100%,对苯二甲酸钠盐(Na_(2)TPA)产率达97.4%;以PET微塑料水解产物为前驱体,发展了2种简易方法制备缺陷型Fe-MOFs催化剂.通过扫描电子显微镜(SEM)、X射线粉末衍射仪(PXRD)、傅里叶红外光谱仪(FT-IR)及X射线光电子能谱仪(XPS)等对缺陷Fe-MOFs催化剂的形貌特征、晶体结构、分子结构以及元素种类进行表征,证明催化剂具有缺陷结构.研究评估了2种催化剂催化臭氧降解AO-7性能,其中D-Fe-MOF催化剂可在3min内完全降解AO-7,反应速率常数达0.926min^(-1),是W-Fe-MOF催化剂和单独臭氧的3.6倍和7.3倍.

关键词： PET微塑料碱性水解升级再造缺陷金属有机框架催化臭氧

Adequate Closed Form Wave Solutions to the Generalized KdV Equation in Mathematical Physics

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Journal of Applied Mathematics and Physics 2024年第6期12卷 2069-2082页

作者： Md. Munnu Miah Md. Al Amin Meia Md. Matiur Rahman Sarker Ahammodullah hasan Department of Mathematics Islamic University Kushtia Bangladesh Department of Mathematics Government Titumir College Dhaka Bangladesh Department of Pharmacy University of Asia Pacific Dhaka Bangladesh

In this paper, we consider the generalized Korteweg-de-Vries (KdV) equations which are remarkable models of the water waves mechanics, the shallow water waves, the quantum mechanics, the ion acoustic waves in plasma, the electro-hydro-dynamical model for local electric field, signal processing waves through optical fibers, etc. We determine the useful and further general exact traveling wave solutions of the above mentioned NLDEs by applying the exp(−τ(ξ))-expansion method by aid of traveling wave transformations. Furthermore, we explain the physical significance of the obtained solutions of its definite values of the involved parameters with graphic representations in order to know the physical phenomena. Finally, we show that the exp(−τ(ξ))-expansion method is convenient, powerful, straightforward and provide more general solutions and can be helping to examine vast amount of travelling wave solutions to the other different kinds of NLDEs.

关键词： The Generalized KdV Equation The exp(-τ(ξ)) -Expansion Method Travelling Wave Solitary Wave

Preparation of Durable Antibacterial Polyester Fabrics by Grafting with the Natural Quaternary Ammonium Compound Betaine

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Materials Sciences and Applications 2024年第9期15卷 378-398页

作者： Md Shariful Islam Md Kamrul hasan Arifur Rahman Shakhauat Hossen Md Anwarul Islam Sachi Xinbo Ding School of Textile Science and Engineering International Silk Institute Zhejiang Sci-Tech University Hangzhou China King Graduate School Monroe College Bronx NY USA

Recently, the textile industry has increasingly advocated for natural resource-based healthcare textiles. This research presents a facile and eco-friendly approach to developing durable antibacterial polyester fabrics. Polyester fabric was first subjected to an alkaline hydrolysis to impart hydroxyl groups on the fiber surface. A natural antibacterial agent, betaine, was then covalently bonded to the hydrolyzed polyester fiber surface through esterification. XPS, Raman, SEM, and Wicking measurements were carried out to verify the esterification reaction. Antibacterial tests confirmed that betaine treatment grafted polyester fabrics revealed a remarkable antibacterial effect with inhibition rates > 99.9% against both E. coli and S. aureus and still remained inhibition rates of up to 91.5% against both bacteria after home washing for 20 cycles. Moreover, the modification significantly increased the capillary effect of polyester fabric but did not cause apparent adverse effects on the fabric’s hand or tensile strength. Overall, this grafting strategy for durable, antibacterial polyester fabric represents a significant practicality in the textile industry.

关键词： Polyester Fabric Betaine Antibacterial Durability Capillary

光驱动Rh/InGaN_(1-x)O_(x)纳米组装体甲烷干重整制合成气

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Science Bulletin 2024年第10期69卷 1400-1409页

作者：李亦昕李景林俞天奇邱亮 Syed M.Najib hasan 姚琳潘虎 Shamsul Arafin Sharif Md.Sadaf 朱磊周宝文 Key Laboratory for Power Machinery and Engineering of Ministry of Education Research Center for Renewable Synthetic FuelSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China China-UK Low Carbon College Shanghai Jiao Tong UniversityShanghai 201306China Centre Energie Matériaux et TélécommunicationsInstitut National de la Recherche Scientifique(INRS)-Universitédu QuébecVarennes J3X 1E4Canada Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH43210USA

Light-driven dry reforming of methane toward syngas presents a proper solution for alleviating climate change and for the sustainable supply of transportation fuels and ***,Rh/InGaN_(1-x)O_(x) nanowires supported by silicon wafer are explored as an ideal platform for loading Rh nanoparticles,thus assembling a new nanoarchitecture for this grand *** combination with the remarkable photothermal synergy,the O atoms in Rh/InGaN_(1-x)O_(x) can significantly lower the apparent activation energy of dry reforming of methane from 2.96 eV downward to 1.70 *** as-designed Rh/InGaN_(1-x)O_(x) NWs nanoarchitecture thus demonstrates a measurable syngas evolution rate of 180.9 mmol g_(cat)^(-1) h^(-1) with a marked selectivity of 96.3% under concentrated light illumination of 6 W cm^(-2).What is more,a high turnover number(TON)of 4182 mol syngas per mole Rh has been realized after six reuse cycles without obvious activity *** correlative 18O isotope labeling experiments,in-situ irradiated X-ray photoelectron spectroscopy(ISI-XPS)and in-situ diffuse reflectance Fourier transform infrared spectroscopy characterizations,as well as density functional theory calculations reveal that under light illumination,Rh/InGaN_(1-x)O_(x) NWs facilitate releasing^(*)CH_(3) and H^(+)from CH_(4) by holes,followed by H_(2) evolution from H^(+)reduction with ***,the O atoms in Rh/InGaN_(1-x)O_(x) can directly participate in CO generation by reacting with the ^(*)C species from CH_(4) dehydrogenation and contributes to the coke elimination,in concurrent formation of O *** resultant O vacancies are then replenished by CO_(2),showing an ideal chemical *** work presents a green strategy for syngas production via light-driven dry reforming of methane.

关键词： Dry reforming of methane Photo-thermal catalysis Rh/InGaN_(1-x)O_(x)nanowires