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Outcomes in patients with COVID-19 and new onset heart blocks: Insight from the National Inpatient Sample database

世界心脏病学杂志:英文版(电子版) 2023年第9期15卷 448-461页

作者： Sami J Shoura Taha Teaima Muhammad Khawar Sana Ayesha Abbasi Ramtej Atluri Mahir Yilmaz hasan hammo Laith Ali Chanavuth Kanitsoraphan Dae Yong Park Tareq Alyousef Department of Internal Medicine John H.Stroger Jr.Hospital of Cook CountyChicagoIL 60612United States Department of Cardiology John H.Stroger Jr Hospital of Cook CountyChicagoIL 60612United States

BACKGROUND Coronavirus disease 2019(COVID-19)caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in a worldwide health crisis since it first *** studies demonstrated the virus’s predilection to cardiomyocytes;however,the effects that COVID-19 has on the cardiac conduc-tion system still need to be fully *** To analyze the impact that COVID-19 has on the odds of major cardiovascular complications in patients with new onset heart blocks or bundle branch blocks(BBB).METHODS The 2020 National Inpatient Sample(NIS)database was used to identify patients admitted for COVID-19 pneumonia with and without high-degree atrioven-tricular blocks(HDAVB)and right or left BBB utilizing ICD-10 *** patients with pre-existing pacemakers,suggestive of a prior diagnosis of HDAVB or BBB,were excluded from the *** primary outcome was inpatient *** outcomes included total hospital charges(THC),the length of hospital stay(LOS),and other major cardiac outcomes detailed in the Results *** and multivariate regression analyses were used to adjust for confounders with Stata version *** A total of 1058815 COVID-19 hospitalizations were identified within the 2020 NIS database,of which 3210(0.4%)and 17365(1.6%)patients were newly diagnosed with HDAVB and BBB,*** observed a significantly higher odds of in-hospital mortality,cardiac arrest,cardiogenic shock,sepsis,arrythmias,and acute kidney injury in the COVID-19 and HDAVB *** was no statistically significant difference in the odds of cerebral infarction or pulmonary *** with COVID-19 pneumonia and newly diagnosed BBB had a higher odds of arrythmias,acute kidney injury,sepsis,need for mechanical ventilation,and cardiogenic shock than those without ***,unlike HDAVB,COVID-19 pneumonia and BBB had no significant impact on mortality compared to patients without *** In conclusion,there is a sign

关键词： In-patient outcomes Severe acute respiratory syndrome coronavirus 2 Coronavirus disease 2019,High degree atrioventricular blocks Bundle branch blocks Retrospective observational study

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