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SARS-CoV-2 variants are associated with different clinical courses in children with MIS-C

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World Journal of Pediatrics 2024年第2期20卷 143-152页

作者： Andres F.Moreno Rojas Emelia Bainto Helen harvey Adriana H.Tremoulet Jane C.Burns Kirsten B.Dummer Department of Pediatrics Division of Pediatric CardiologyUniversity of California San Diegoand Rady Children’s Hospital3020 Children’s Way MC 5004San DiegoCA 92123USA Kawasaki Disease Research Center La JollaCAUSA Department of Pediatrics Division of Pediatric Critical CareUniversity of California San Diegoand Rady Children’s HospitalSan DiegoCAUSA Department of Pediatrics University of California San Diegoand Rady Children’s HospitalSan DiegoCAUSA

Background Recent infection with SARS‑CoV-2 in children has been associated with multisystem inflammatory syndrome in children(MIS-C).SARS‑CoV-2 has undergone different *** publications exist about specific variants and their correlation with the severity of *** This was a single-center,retrospective study including all patients admitted with MIS-C at Rady Children’s Hospital-San Diego between May 2020 and March *** epidemiologic data,including viral genomic information,were obtained from public ***,clinical presentation,laboratory values,and outcomes were obtained from electronic medical *** The analysis included 104 pediatric *** MIS-C waves were *** variants in San Diego during the first wave included clades 20A to *** the second wave,there were variants from clades 20A to C,20G,21C(Epsilon),20I(Alpha),and 20J(Gamma).The third wave had Delta strains(clades 21A,21I,and 21J),and the fourth had Omicron variants(clades 21K,21L,and 22C).MIS-C presented with similar symptoms and laboratory findings across all *** patients were admitted to the pediatric intensive care unit(PICU)(74%)and required inotropic support(63%)during the second *** of the patients required mechanical circulatory support,and only two required invasive ventilatory *** was no *** The various strains of SARS-CoV-2 triggered MIS-C with differing severities,with the second wave having a more severe clinical *** the differences in disease severity across variants were due to changes in the virus or other factors remains unknown.

关键词： Complications COVID-19 MIS-C SARS-CoV-2 variants

Geometric phase helical PSF for simultaneous orientation and 3D localization microscopy

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Chinese Optics Letters 2024年第3期22卷 25-30页

作者：周勇壮张洪硕沈咏 Andrew R.harvey 邹宏新 Institute for Quantum Science and Technology College of ScienceNational University of Defense TechnologyChangsha 410073China Hunan Key Laboratory of Mechanism and Technology of Quantum Information Changsha 410073China School of Physics and Astronomy University of GlasgowGlasgow G128QQUK

The 3D location and dipole orientation of light emitters provide essential information in many biological,chemical,and physical *** acquisition of both information types typically requires pupil engineering for 3D localization and dual-channel polarization splitting for orientation *** we report a geometric phase helical point spread function for simultaneously estimating the 3D position and dipole orientation of point *** has a compact and simpler optical configuration compared to polarization-splitting techniques and yields achromatic phase modulation in contrast to pupil engineering based on dynamic phase,showing great potential for single-molecule orientation and localization microscopy.

关键词： PSF engineering geometric phase single-molecule orientation and localization microscopy

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Cognitive function among military veterans with STEM occupations

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Military Medical Research 2024年第2期11卷 308-310页

作者： Justin T.McDaniel Kevin N.Hascup Erin R.Hascup Ugochukwu G.Ezigbo Amanda M.Weidhuner harvey Henson David L.Albright Dale and Deborah Smith Center for Alzheimer's Research and trEatment(CARE) Southern Illinois University School of MedicineSpringfieldIL 62794USA STEM Education Research Center Southern Illinois UniversityCarbondaleIL 62901USA Department of Political Science The University of AlabamaTuscaloosaAL 35487USA

Dear Editor,There is limited research on the relationship between science,technology,engineering,and mathematics(STEM)occupational history and cognitive function in later life,especially among military veterans,who may be at greater risk for later-life cognitive *** study examines a nationally representative sample of military veterans to address this gap in knowledge.

关键词： Alzheimer's disease Veterans Science technology engineering and mathematics(STEM) Animal fluency test Dementia

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Kaoline-based catalyst for a high stability desulfurization of sour heavy naphtha in a three-phase oscillatory baffled reactor

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Particuology 2024年第1期84卷 249-260页

作者： Hassan M.Hmood Saba A.Gheni Safaa M.R.Ahmed Mudheher M.Ali Hamid Yonis Saleh Mohammed H.Mohammed Awad E.Mohammed Marwan A.Mahomood Hiba R.Mohammed Ahmed A.Hassan Adam harvey North Refineries Company Ministry of OilIraq Chemical Engineering Department Tikrit UniversityIraq Ministry of Oil Iraq AL-Hawija Technical Institute Northern Technical UniversityMoselIraq School of Engineering Newcastle UniversityUK

To meet the rapidly increasing demand for energy and the dramatic depletion of conventional crude oil,it is imperative to utilize sour *** no coke being produced,oxidative desulfurization(ODS)of naphtha lowers its sulfur content and average molecular *** this article,we outline a method for heavy naphtha non-extractive ODS using a very stable *** technique involves the use of a solid catalyst with oxygen gas as the *** necessitated relatively high mixing intensities;hence a three-phase Oscillatory Baffled Reactor(OBR)was *** catalyst was based on the zeolite ZSM-5,prepared from natural kaolin by a series of delamination and activation steps and impregnated with Fe.A TiO2 nanolayer was applied,using the sol-gel method,to prevent rapid *** reactor performance was evaluated to minimize the sulfur content in the naphtha *** to the protective coating,the sulfur conversion stabilized at 90%.The results of this work establish the use of natural clay-based catalysts in a continuous,three-phase ODS,particularly with regard to proving long-term *** also showed that modest ODS can be achieved using an environmentally friendly oxidant,at mild operating conditions,whilst maintaining stability.

关键词： Natural kaoline Desulfurization Three-phase Oscillatory baffled reactor

以字筑城：柏林城市品牌视觉形象构建与传播中的字体应用初探

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艺海 2024年第06期 66-70页

作者：苏丰李丹 Max harvey 湖南师范大学

自1990年联邦德国与民主德国重新统一至今，柏林市前后启动“be Berlin”及“We are one Berlin”两项旨在重塑其开放、多元、包容的大首都城市精神的品牌形象推广活动，并推出与之相匹配的两套城市视觉识别系统设计。其中，两款定制... 详细信息

自1990年联邦德国与民主德国重新统一至今，柏林市前后启动“be Berlin”及“We are one Berlin”两项旨在重塑其开放、多元、包容的大首都城市精神的品牌形象推广活动，并推出与之相匹配的两套城市视觉识别系统设计。其中，两款定制字体“be Berlin”与“Berlin Type”伴随着活动的推进，渗透到柏林城市生活的各个层面，形成一道由字体构筑的独特城市风景线并甚而成为新柏林独特城市文化特质与底蕴的重要表征，在城市文化的流转过程中发挥着极其重要的作用。作为现代城市品牌视觉形象构建与推广的先行者，柏林所取得的成果与经验无疑能够为我国城市建设提供宝贵的参考。

关键词：城市品牌形象城市视觉识别系统字体设计

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诺曼底行动中的神奇发明

环球科学 2024年第16期 58-63页

作者：艾尔萨·哈维不详

诺曼底登陆日(D-Day)已经过去80年了。作为解放德占西欧地区的“霸王行动”的一部分,在这一天,盟军在法国诺曼底海岸发起了一次登陆作战。1944年6月6日,156000多名盟军士兵在这片被纳粹德军占领的地区浴血奋战,为结束德军在法国的统治... 详细信息

诺曼底登陆日(D-Day)已经过去80年了。作为解放德占西欧地区的“霸王行动”的一部分,在这一天,盟军在法国诺曼底海岸发起了一次登陆作战。1944年6月6日,156000多名盟军士兵在这片被纳粹德军占领的地区浴血奋战,为结束德军在法国的统治奠定了基础。

关键词：诺曼底登陆登陆作战西欧地区盟军法国

A route to enhanced performance for the petawatt beamlines of the Orion laser facility

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High Power Laser Science and Engineering 2022年第3期10卷 11-18页

作者： E.J.harvey AWE AldermastonReadingRG74PRUK

The Orion laser facility at AWE provides multiple beams to target delivering synchronized pulses at both nanosecond and sub-picosecond *** the latter,the peak power approaches the petawatt *** paper presents a conceptual design for potential development of these *** would deliver a significant enhancement of performance at the fundamental *** addition,a new approach is described for the management of frequency conversion at high intensity,which may allow significantly enhanced performance at the second harmonic also.

关键词： chirped pulse amplification frequency doubling temporal contrast

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宇航员训练手册

环球科学 2024年第14期 38-43页

作者：艾尔萨·哈维不详

为了维持身心健康、适应密闭环境和操作尖端仪器,宇航员在太空必须严格锻炼身体。很多人都梦想成为宇航员,毕竟在几百千米高的太空轨道上俯看地球是极少数人的专属体验。对宇航员来说,这也是对他们长期付出的肯定和嘉奖。一名合格的宇... 详细信息

为了维持身心健康、适应密闭环境和操作尖端仪器,宇航员在太空必须严格锻炼身体。很多人都梦想成为宇航员,毕竟在几百千米高的太空轨道上俯看地球是极少数人的专属体验。对宇航员来说,这也是对他们长期付出的肯定和嘉奖。一名合格的宇航员需要掌握十八般武艺,比如开展实验所需的科学知识,在极端环境下保持健康的强健体魄和适应能力,以及战胜太空特有的孤独感和逼庆舱内环境的顽强意志。太空探索充满变数,宇航员要面对繁重的工作,适应陌生的环境,处理各种突发状况。

关键词：太空探索密闭环境强健体魄极端环境训练手册突发状况宇航员锻炼身体

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机场的聪明大脑

环球科学 2024年第4期 42-47页

作者：艾尔萨·哈维不详

每天,世界各地机场有约10万架次的商业航班起飞。每时每刻都有成千上万的人在空中飞行,因此,作为交通基础设施的机场必须在每个流程都保证高效、安全地运作,包括从停车场入口到航站楼的快速交通、规范的空中交通管制以及对航班上人员和... 详细信息

每天,世界各地机场有约10万架次的商业航班起飞。每时每刻都有成千上万的人在空中飞行,因此,作为交通基础设施的机场必须在每个流程都保证高效、安全地运作,包括从停车场入口到航站楼的快速交通、规范的空中交通管制以及对航班上人员和物品的安全检查。

关键词：交通基础设施快速交通安全检查停车场航站楼空中交通管制机场商业航班