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Occurrence of myelodysplastic syndrome during paclitaxel- and carboplatin-based chemotherapy for recurrent ovarian cancer: Case report

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Open Journal of Obstetrics and Gynecology 2013年第2期3卷 232-234页

作者： Hiroshi takagi Satoshi Ichigo Kazutoshi Matsunami haruna takagi Tsuneko Ikeda Takayuki Murase Atsushi Imai Department of Obstetrics and Gynecology Matsunami General Hospital Gifu Japan Department of Pathology Matsunami General Hospital Kasamatsu Gifu Japan

Platinum and taxane have significant activity as key drugs in current treatment of advanced ovarian cancer. While myelodysplastic syndrome (MDS) and acute leukemia are wellknown secondary disease after administration of chemotherapy, particularly with alkylating agents, they have only rarely been reported in the context of ovarian cancer treatment. In this case report a 59-year-old Japanese developed a MSD during ongoing second induction chemotherapy with carboplatin and paclitaxel for recurrent ovarian cancer. Her second induction began 9 months after completion of her first course of chemotherapy. Cytogenetic analyses showed typical chromosomal aberration. Although the finding of pancytopenia is also seen during chemotherapy without MSD/acute leukemia, bone marrow aspiration and biopsy should be considered to confirm the clinical suspicion of the lifethreatening disease when encountered persistent pancytopenia following carboplatin and paclitaxel-based chemotherapy in an ovarian cancer patient.

关键词： Chemotherapy-Related Myelodysplastic Syndrome Ovarian Cancer Platinum Taxane

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Piezoelectric Power Harvesting Process via Phase Changes of Low-Boiling-Point Medium Together with Water for Recovering Low-Temperature Heats

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Journal of Power and Energy Engineering 2018年第11期6卷 65-77页

作者： Seiichi Deguchi Akinori Miyajima Hajime Arimura haruna Banno Noriyuki Kobayashi Norifumi Isu Kentaro takagi Tsuyoshi Inoue Takashi Nozoe Seigo Saito Takahiko Sano Department of Chemical Process Engineering Nagoya University Nagoya Japan Analysis & Assessment Center LIXIL Corporation Noda Japan Department of Mechanical Systems Engineering Nagoya University Nagoya Japan Fuji Ceramics Corporation Fujinomiya Japan

Low-temperature thermal energy conversions down to exergy zero to electric power must contribute energy sustainability. That is to say, reinforcements of power harvesting technologies from extremely low temperatures less than 373 K might be at least one of minimum roles for the current generations. Then, piezoelectric power harvesting process for recovering low-temperature heats was invented by using a unique biphasic operating medium of an underlying water-insoluble/low-boiling-point medium (i.e. NOVEC manufactured by 3M Japan Ltd.) in small quantity and upper-layered water in large quantity. The higher piezoelectric power harvesting densities were naturally revealed with an increase in heating temperatures. Excessive cooling of the operating medium deteriorated the power harvesting efficiency. The denser operating medium was surpassingly helpful to the higher piezoelectric power harvesting density. Concretely, only about 5% density increase of main operating medium (i.e. water with dissolving alum at 0.10 mol/dm3) came to the champion piezoelectric power harvesting density of 92.6 pW/dm2 in this study, which was about 1.4 times compared to that with the original biphasic medium of pure water together with a small quantity of NOVEC.

关键词： Piezoelectric Power Generation Low-Temperature Heat Recovery Biphasic Medium Phase Change Multiphase Flow Power Harvesting

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