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口服抗凝治疗安全地预防老年人心房颤动患者发生脑卒中

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英国医学杂志中文版 2010年第2期13卷 113-114页

作者： van Walraven C hart rg Connolly S 赵振燕(译) 李崇剑(校) 吴永健(校) 不详北京阜外心血管病医院心内科

研究设计设计：对12项随机对照试验中个体的资料进行汇总分析。6项随机对照试验是安慰剂对照试验，8项是比较口服抗凝药与抗血小板药物的随机对照试验。

关键词：心房颤动患者口服抗凝治疗随机对照试验脑卒中老年人预防安全抗血小板药物

An Algorithm for Constructing 3D Struts

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Journal of Computer Science & Technology 2009年第1期24卷 56-64页

作者： George W.hart Department of Computer Science Stony Brook UniversityStony BrookNY 11794U.S.A.

A simple robust ＂strut algorithm＂ is presented which, when given a graph embedded in 3D space, thickens its edges into solid struts. Various applications, crystallographic and sculptural, are shown in which smooth high-genus forms are the output. A toolbox of algorithmic techniques allow for a variety of novel, visually engaging forms that express a mathematical aesthetic. In sculptural examples, hyperbolic tessellations in the Poincare plane are transformed in several ways to three-dimensional networks of edges embodied within a plausibly organic organization. By the use of different transformations and adjustable parameters in the algorithms, a variety of attractive forms result. The techniques produce watertight boundary representations that can be built with solid freeform fabrication equipment. The final physical output satisfies the ＂coolness criterion,＂ that passers by will pick them up and say ＂Wow, that＇s cool!＂

关键词： sculpture solid modeling echinoderm algorithms fine arts computer-aided design

The delivery of effective therapeutic cancer vaccination

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Asian Journal of Andrology 2011年第2期13卷 183-184页

作者： Derek hart Dendritic Cell Biology and Therapeutics ANZACResearch Institute Sydney NSW 2139 Australia

The recent New England Journal of Medicine article describing the Phase3 placebo controlled trial （Immunotherapy for Prostate Andenocarcinoma Treatment） was much anticipated. Its publication and peer review brings down the curtain on the, at times controversial, application by Dendreon to the US Food and Drug Administration. The Immunotherapy for Prostate Andenocarcinoma Treatment data lead to the US Food and Drug Administration＇s final approval in April of the product sipuleucel-T （Provenge） as the first therapeutic vaccine for use in individuals with asymptomatic or minimally symptomatic hormone refractory metastatic prostate cancer.

关键词： Prostate Immunotherapy Drugs Immunity Vaccines Vaccination Administration Managers Cancer (genus) Uses

Explaining surface interactions for common associated gangues of rare earth minerals in response to the oxalic acid

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International Journal of Mining Science and Technology 2018年第2期28卷 343-346页

作者： Saeed Chehreh Chelgani Brian hart Department of Electrical Engineering and Computer Science University of Michigan Surface Science Western University of Western Ontario

In the flotation of rare earth minerals(REMs), oxalic acid is reportedly acting both as a depressant and p H modifier. Although results of testing have established the significance of oxalic acid in the flotation process, its specific role in either the recovery or selectivity of REMs over their common gangue minerals is not well understood. Pulp p H reduction trials with alternative acids have not shown the same effect on the REMs recovery or the depression of gangue phases. This work studies the effect of oxalic acid on the surface of common REMs gangue minerals(quartz and carbonates(dolomite and calcite)) in a series of conditioning tests. Gangue surface analyses by time of flight secondary ion mass spectroscopy(TOFSIMS) indicate that oxalic acid inhibits the transfer of secondary ions generated during the conditioning process from one mineral to another. In this regard, the oxalate anion acts to fix ions in solution through chelation, limiting their participation in surface adsorption.

关键词： Oxalic acid Rare earth Silicate Carbonate TOF-SIMS

Introduction:Image and Text

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外国文学研究 2019年第4期41卷 14-15页

作者： Jonathan Locke hart 不详

Image and word, as expressed in pictures and works or texts, is an old relation in East and ***,wemovefromthegeneraltheoreticalcontext,moreexpressedin ***(UniversityofCalifornia,Irvine),tomattersconcerningthe RenaissanceandBéroaldede Verville,LeVoyagedesprincesfortunez,assetoutby Tom Conley (Harvard), and Shakespeare and Tang Xianzu, as explored by Liu Hao (Tsinghua).

关键词： Introduction Image Text

Quantitative study on pollen-based reconstructions of vegetation history from central Canada

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Science China Earth Sciences 2008年第8期51卷 1081-1088页

作者： hart Catherina VETTER Mary SAUCHYN David Department of Biology University of ReginaS4S 0A2Canada Prairie Adaptation Research Collaborative SK S4S 7J7Canada Department of GeographyUniversity of ReginaS4S 0A2Canada

Based on high-resolution pollen records from lake cores in central Canada, the present study instructed pollen taxa assignations in ecosystem groups and modern analogue technique, reported major results of quantitativ... 详细信息

关键词： sedimentary pollen surface pollen modern analogue technique ecosystem paleovegetation past 1000 years

Additive manufacturing of flexible 3D surface electrodes for electrostatic adhesion control and smart robotic gripping

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Friction 2023年第11期11卷 1974-1986页

作者： Dong Geun KIM Hyeongmin JE AJohn hart Sanha KIM Department of Mechanical Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea Department of Mechanical Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA

Mechanically flexible surface structures with embedded conductive electrodes are attractive in contact-based devices,such as those used in reversible dry/adhesion and tactile *** shapes of the surface structures strongly determine the contact behavior and therefore the resulting adhesion and sensing functionalities;however,available features are often restricted by fabrication ***,we additively manufacture elastomeric structure arrays with diverse angles,shapes,and sizes;this is followed by integration of conductive nanowire *** fabricated flexible three-dimensional(3D)surface electrodes are mechanically compliant and electrically conductive,providing multifunctional ability to sense touch and to switch adhesion via a combined effect of shear-and electro *** designed soft,anisotropic flexible structures to mimic the gecko’s reversible adhesion,which is governed by van der Waals forces;we integrated nanowires to further manipulate the localized electric field among the adjacent flexible 3D surface electrodes to provide additional means to digitally tune the electrostatic attraction at the contact *** addition,the composite surface can sense the contact force via capacitive *** our flexible 3D surface electrodes,we demonstrate a complete soft gripper that can grasp diverse convex objects,including metal,ceramic,and plastic products,as well as fresh fruits,and that exhibits 72%greater electroadhesive gripping force when voltage is applied.

关键词： electroadhesion tactile sensing robotic gripper additive manufacturing dry adhesive

Trace Elements and Sr, Nd Isotope Geochemistry of the Lajimiao Norite-Gabbro from the North Qinling Belt

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Acta Geologica Sinica(English Edition) 1994年第2期68卷 137-151页

作者： S.R.hart Department of Geology and Geopphysics Woods Hole Oceanographic InstituteWoods

The Lajimiao norite-gabbro complex, as a part of the ophiolites on the southern side of the North Qinling belt, consists of gabbro and norite-gabbro. They were derived from different magma series: the gabbro was derived from tholeiitic magma series with higher TiO2, REE abundance and Fe3+/Fe2+ ratio ; norite-gabbro was derived from calc-alkali magma series with lower TiO2, Fe3+/Fe2+ ratio and REE abundance and much lower HREE abundance, which suggests that the source of the norite-gabbro magma was deeper and controlled by eclogite facies. Geochemical characteristics of both plutonic rocks are similar to those of island-arc basalts, such as relatively high contents of Ba, Pb and Sr and relatively low contents of Nb, Zr and N *** Sr, Nd isotopic characteristics of the Lajimiao norite-gabbro complex are similar to those of ophiolites. Its εNd values are constant, about+2; whereas εst values have wide variation from - 6.4 to +31.2 and positively correlate with Na2O, H2O+ and CO2 contents and the Fe3+/Fe2+ ratio. The εNd- Nd/Th, εNd- La/Nb and εNd-Ba/Nb diagrams clearly show that there were significant components of terrigenous sediments in the mantle source of the Lajimiao norite-gabbro complex. It suggests that large amount of sediments had been carried into the mantle by the subducted ancient Qinling sea plate during the Palaeozoic.

关键词： trace element Sr/Nd isotopes norite-gabbro Lajimiao North Qinling

Recent progress of fully synthetic carbohydrate-based vaccine using TLR agonist as build-in adjuvant

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Chinese Chemical Letters 2018年第1期29卷 19-26页

作者： Zhifang Zhou hart Lin Chen Li Zhimeng Wu iangnan University Wuxi 214122 China

Fully synthetic vaccine, in which one or multi-molecular antigens are conjugated to a synthetic carrier with well-defined chemical structure, is a new direction to develop carbohydrate-based vaccine against cancer and pathogens. Toll like receptor （TLR） agonists with the ability to stimulate immune response have been widely investigated and been applied as build-in adjuvants to construct fully synthetic vaccines. In particular, remarkable progress has been achieved in recent years in the development of vaccines constructed with the agonists of TLRI]2, TLR2/6 and TLR4 and tumor-associated carbohydrate antigens （TACAs）. These di-, tri- or multi-component vaccine candidates showed attractive immunologi- cal properties. This review highlights recent advances in developing full synthetic carbohydrate antigen based vaccines, with an emphasis on the structure-activity relationships that provide a primary basis for future vaccine design and immunotherapy developing.

关键词： Fully synthetic vaccineTLR agonistBuild-in adjuvantCarbohydrate-based vaccineTACAs