检索结果-南通市图书馆

A One Health approach to fight antimicrobial resistance in Uganda: Implementation experience, results, and lessons learned

引用

Biosafety and Health 2024年第2期6卷 125-132页

作者： Reuben Kiggundu J.P.Waswa Niranjan Konduri Hassan Kasuja Marion Murungi Patrick Vudriko harriet akello Eric Lugada Cecilia Muiva Esther Were Dinah Tjipura Henry Kajumbula Kate Kikule Emmanuel Nfor Mohan P.Joshi USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthArlingtonVA 22203USA College of Veterinary Medicine Animal Resources and BiosecurityMakerere UniversityKampala 256Uganda Ministry of Health Uganda Kampala 256Uganda USAID Strengthening Supply Chain Systems Activity Management Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthNairobi 254Kenya Department of Microbiology College of Health SciencesMakerere UniversityKampala 256Uganda

Uganda has been implementing the Global Health Security Agenda(GHSA)since 2015 to build its capacity according to World Health Organization(WHO)Benchmarks on International Health Regulations *** country remains prone to outbreaks,with more than 20 disease outbreaks reported in the past five years,including Ebola virus disease,Crimean-Congo haemorrhagic fever,Marburg haemorrhagic fever,measles,yellow fever,coronavirus disease 2019(COVID-19),and *** resistance(AMR)is an ongoing *** scored capacity level 3 on infection prevention and control(IPC)and antimicrobial stewardship(AMS)in the 2017 Joint External Evaluation(JEE)*** gaps were being addressed after a self-assessment in *** paper describes the technical assistance approaches provided to Uganda by the Medicines,Technologies,and Pharmaceutical Services Program,funded by the United States(U.S.)Agency for International Development,and implemented by Management Sciences for *** program,through a One Health approach,supported systematic capacity strengthening based on the JEE's capacity advancement framework for global health security,specifically relating to *** program's interventions impacted 32 WHO benchmark actions(7 for AMR multisectoral coordination,16 for IPC,and 9 for AMS),contributing to Uganda's strengthened GHSA *** success built on the AMR platform,the program trained 745 health workers in IPC for the Ebola virus and provided support for simulation exercises by eight district IPC *** program also worked with the Ministry of Health to coordinate IPC for the COVID-19 response in five health regions,covering 45 districts and reaching 5,452 health workers at 858 health facilities.

关键词： One health Antimicrobial resistance Antibiotic resistance Jointexternal evaluation Global health security Uganda Africa WHO Benchmarks for International Health Regulations Capacities

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Conceptualising Intangible Heritage in Urban Environments: Challenges for Implementing the HUL Recommendation

引用

Built Heritage 2018年第4期2卷 72-81页

作者： harriet Jane Deacon Centre for Dance Research Coventry UniversityCoventryUnited Kingdom

The Historic Urban Landscape(HUL)Recommendation(UNESCO 2011)suggests that heritage management should be holistic,integrated,people-centred and focused on sustainable development *** tangible and intangible heritage should be taken into account,allowing for appropriate change over time.A variety of stakeholders should be involved in planning processes,including all levels of government,NGOs and *** dialogue and mediation,as well as tools such as documentation,inventorying and mapping should be used to identify multiple layers of *** the Recommendation thus offers a wonderful opportunity to develop consultative,bottom-up,integrated planning for sustainable development in urban *** paper suggests that one barrier to integrating management planning for tangible and intangible heritage is a persistent confusion about what‘intangible heritage’is and why it deserves *** it the values that local communities associate with their environment(‘intangible values’),or is it cultural practices that they happen to perform in that environment(intangible cultural heritage,or ICH)?Should‘intangible heritage’be managed as an attribute attesting to the authenticity of tangible fabric,or as a subject of safeguarding in its own right?If it means all these things at the same time,why is the same concept being used for so many different ideas and what are the consequences?The paper will suggest that a clearer conceptual understanding of intangible heritage is necessary to effectively integrate it into urban management strategies under the HUL approach.

关键词： intangible heritage Historic Urban Landscape UNESCO intangible heritage convention

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thermochemical splitting of carbon dioxide by lanthanum manganites-understanding the mechanistic effects of doping

引用

Energy Storage and Saving 2022年第4期1卷 309-324页

作者： harriet Kildahl Hui Cao Yulong Ding School of Chemical Engineering University of BirminghamB152TTUnited Kingdom

This review investigates the effect of different dopants on the oxygen evolution and carbon dioxide splitting abilities of the lanthanum *** focus was placed on the lanthanide,alkaline earth metals,redox-active transition metal,and non-redox active Group 3 *** review suggests that a small ionic radius lanthanide on the A-site can increase the size discrepancy,leading to Mn-O_(6) octahedra tilting and more facile Mn-O bond *** the A-site with a divalent alkaline earth element can increase the valance of the transition metal,leading to greater reduction capabilities.A transition metal with one electron in the e_(g) orbital is the most effective for reduction while for oxidation,zero electrons in the high-energy e_(g) orbitals is ***,doping of the B-site with metals such as gallium or aluminium aids in sintering resistance and allows reactivity to remain constant over multiple *** reduction temperatures and moderate re-oxidation temperatures also promote higher fuel yields as does the active reduction of the perovskite under hydrogen,although the total energy consumption implications of this are *** more is known about the mechanism of the reduction reaction than the oxidation reaction,therefore more research in this area is required.

关键词： CO_(2)splitting Thermochemical cycle Perovskite Energy conversion Doping

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thermochemical splitting of CO_(2) on perovskites for CO production: A review

引用

Journal of Energy Chemistry 2024年第3期90卷 464-485,I0011页

作者： Biduan Chen harriet Kildahl Hui Yang Yulong Ding Lige Tong Li Wang School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083China School of Chemical Engineering University of BirminghamBirmingham B152TTUnited Kingdom Beijing Engineering Research Centre of Energy Saving and Environmental Protection Beijing 100083China

Energy supply dominated by fossil energy has been and remains the main cause of carbon dioxide emissions,the major greenhouse gas leading to the current grave climate change *** technical pathways have been proposed to address the *** capture and utilization(CCU) represents one of the approaches and thermochemical CO_(2) splitting driven by thermal energy is a subset of the CCU,which converts the captured CO_(2) into CO and makes it possible to achieve closed-loop carbon ***-active catalysts are among the most critical components of the thermochemical splitting cycles and perovskites are regarded as the most promising *** we review the latest advancements in thermochemical cycles based on perovskites,covering thermodynamic principles,material modifications,reaction kinetics,oxygen pressure control,circular strategies,and demonstrations to provide a comprehensive overview of the topical *** cycles based on such materials require the consideration of trade-off between cost and efficiency,which is related to actual material used,operation mode,oxygen removal,and heat *** of efforts have been made towards improving reaction rates,conversion efficiency and cycling stability,materials related research has been lacking-a key aspect affecting the performance across all above *** perovskites and composite perovskites arise recently as a potentially promising addition to material *** such materials,more effective oxygen removal would be needed to enhance the overall efficiency,for which thermochemical or electrochemical oxygen pumps could contribute to efficient oxygen removal as well as serve as means for inert gas *** integration of thermochemical CO_(2) splitting process with downstream fuel production and other processes could reduce costs and increase efficiency of the *** represents one of the directions for the future research.

关键词： Perovskite Thermochemical cycles CO_(2) splitting Fuel production Non-stoichiometric

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

China-Ghana Education Cooperation：History and Reality

China-Ghana Education Cooperation：History and Reality

引用

作者： OWUSU harriet ANSAH 华中师范大学

学位级别：硕士

加纳与中国关系源远流长,早在1950年,中国与加纳就建立起教育合作机制。为了实现这一目标,中国在过去几十年里,发起“中非合作论坛”和“南南合作”之类的倡议来加强国际教育合作。本研究探讨了中国在非洲大陆的参与过程,并特别探讨了... 详细信息

加纳与中国关系源远流长,早在1950年,中国与加纳就建立起教育合作机制。为了实现这一目标,中国在过去几十年里,发起“中非合作论坛”和“南南合作”之类的倡议来加强国际教育合作。本研究探讨了中国在非洲大陆的参与过程,并特别探讨了过去的几年中,外国留学生来中国继续深造并接受高等教育的呈上升趋势的原因。从历史的角度出发,本文提出了多种假设并得出一种观点,即中国并没有与欧洲国家和美国竞争以谋求在非洲和世界范围内的霸权地位。如果有竞争的话,中国寻求通过教育合作、技术技能培训和专门知识来帮助第三世界跟上世界其它地区的步伐。所有的这些帮助使参与各国之间互惠互利,包括“中非合作论坛”和“南南倡议”。本研究从历史出发,探讨了中国与非洲历来的交往。双边关系发展到如今,旨在加强与非洲大陆的务实、互利关系,促进了加纳的经济增长和发展。

关键词：教育合作南南合作全球化中国加纳关系

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Methane and Hydrogen Storage in Metal Organic Frameworks: A Mini Review

引用

Journal of Environmental & Earth Sciences 2020年第2期2卷 56-68页

作者： Oghenegare Emmanuel Eyankware Idaeresoari harriet Ateke TegaFej Consulting Services Port HarcourtRivers StateNigeria Department of Petroleum and Gas Engineering University of Port HarcourtRivers stateNigeria

The need for a net zero carbon emission future is imperative forenvironmental sustainability hence, intensive carbon fuels would need tobe replaced with less carbon emitting energy sources such as natural gastill clean energy source such as hydrogen becomes commercialized. Asa result, this mini review discusses the use of metal organic framework(MOF) for adsorption of methane and hydrogen in specially designed tanksfor improved performance so as to increase their applicability. Herein,adsorption (delivery) capacity of selected high performing MOFs formethane and hydrogen storage were highlighted in reference to the targetsset by United States Department of Energy’s Advanced Research ProjectsAgency-Energy (ARPA-E) and Fuel Cells Technology Office. In thisregard, specific design and chemistry of MOFs for improved methane andhydrogen adsorption were highlighted accordingly. In addition, an overviewof computational and molecular studies of hypothetical MOFs was done- the various approaches used and their proficiency for construction ofspecific of crystalline structures and topologies were herewith discussed.

关键词： Methane Hydrogen Metal organic framework Adsorption Storage Computational

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Detection of alcoholic liver disease

引用

World Journal of Gastroenterology 2001年第3期7卷 297-302页

作者： harriet Gordon Consultant Physician and Gastroenterologist The Royal Hampshire County HospitalWinchesterHampshireUK

INTRODUCTIONAlcohol has been used in society over centuries and all over the world for its mood-lifting properties and taste. It is probably ,however ,the commonest drug of abuse world-wide and unfortunately causes considerable morbidity, mortality and social disruption .In 1990 the cost tl the USA was more than $ 100 billion and 100 000 lives.The relationship between alcohol and mankind is well documented from the earliest tines .

关键词： Biological Markers Humans Liver Diseases, Alcoholic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Connecting brain and body:Transdiagnostic relevance of connective tissue variants to neuropsychiatric symptom expression

引用

World Journal of Psychiatry 2021年第10期11卷 805-820页

作者： harriet Emma Clare Sharp Hugo D Critchley Jessica A Eccles Department of Medical Neuroscience Brighton and Sussex Medical SchoolUniversity of SussexBrighton BN19PXEast SussexUnited Kingdom Department of Psychiatry Sussex Partnership NHS Foundation TrustWorthingBN133EPWest SussexUnited Kingdom

The mind is embodied;thoughts and feelings interact with states of physiological arousal and physical integrity of the *** this context,there is mounting evidence for an association between psychiatric presentations and the expression variant connective tissue,commonly recognised as joint *** hypermobility is common,frequently under-recognised,significantly impacts quality of life,and can exist in isolation or as the hallmark of hypermobility spectrum disorders(encompassing joint hypermobility syndrome and hypermobile Ehlers-Danlos syndrome).In this narrative review,we appraise the current evidence linking psychiatric disorders across the lifespan,beginning with the relatively well-established connection with anxiety,to *** next consider emerging associations with affective illnesses,eating disorders,alongside less well researched links with personality disorders,substance misuse and *** then review related findings relevant to neurodevelopmental disorders and stress-sensitive medical *** growing understanding of mind-body interactions,we discuss potential aetiopathogenetic contributions of dysautonomia,aberrant interoceptive processing,immune dysregulation and proprioceptive impairments in the context of psychosocial stressors and genetic *** examine clinical implications of these evolving findings,calling for increased awareness amongst healthcare professionals of the transdiagnostic nature of hypermobility and related disorders.A role for early screening and detection of hypermobility in those presenting with mental health and somatic symptoms is further highlighted,with a view to facilitate preventative approaches alongside longer-term holistic management ***,suggestions are offered for directions of future scientific exploration which may be key to further delineating fundamental mind-body-brain interactions.

关键词： Joint hypermobility Hypermobile Ehlers-Danlos syndrome Psychopathology Psychiatric disorders Neurodevelopmental disorders Mind-body relations

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bleeding after suction rectal biopsy with Rbi2:identification of the root cause through a multi-staged approach

引用

World Journal of Pediatric Surgery 2021年第4期4卷 57-59页

作者： harriet J Corbett Ramanand Jeeneea Iain Hennessey Department of Surgery Royal Liverpool Childrens NHS TrustLiverpoolUK

Introduction Suction rectal biopsy(SRB)is a key diagnostic tool in Hirschsprung’s *** original Noblett device has been superseded by modern alternatives including the Rbi2 rectal biopsy *** describe a comparison of biopsy results from the Noblett device and the Rbi2 gun and an investigation into significant post-biopsy bleeding episodes with the *** A retrospective review of SRB episodes between 2006 and 2014 was undertaken to audit biopsy success *** post-procedure bleeding after SRB with the Rbi2 gun prompted further *** Biopsies taken with the Noblett gun were more likely to be inadequate(Noblett 82/197(40%)vs Rbi277/438(18%)).After biopsy with the Rbi2 gun,2 infants suffered from significant bleeding requiring resuscitation,blood product support and multiple theater *** there were no reported cases of bleeding with the Rbi2 gun,a report was made to the Medicines&Healthcare products Regulatory Agency who identified incorrect biopsy technique as a potential contributing factor.A questionnaire of trainees and consultants found unexpected individual variation in SRB technique,with some users applying excessive *** Significant bleeding occurred after SRB with the Rbi2 gun,excessive suction was thought to be the cause.

关键词： biopsy prompt likely

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nucleotide sequence conservation of novel and established cis-regulatory sites within the tyrosine hydroxylase gene promoter

引用

Frontiers in Biology 2015年第1期10卷 74-90页

作者： Meng WANG Kasturi BANERJEE harriet BAKER John W. CAVE Burke Medical Research Institute White Plains NY 10605 USA Weill Cornell Medical College Brain and Mind Research Institute NY 10065 USA

Tyrosine hydroxylase （TH） is the rate-limiting enzyme in catecholamine biosynthesis and its gene proximal promoter （〈 1 kb upstream from the transcription start site） is essential for regulating transcription in both the developing and adult nervous systems. Several putative regulatory elements within the TH proximal promoter have been reported, but evolutionary conservation of these dements has not been thoroughly investigated. Since many vertebrate species are used to model development, function and disorders of human catecholaminergic neurons, identifying evolutionarily conserved transcription regulatory mechanisms is a high priority. In this study, we align TH proximal promoter nucleotide sequences from several vertebrate species to identify evolutionarUy conserved motifs. This analysis identified three elements （a TATA box, cyclic AMP response element （CRE） and a 5＇-GGTGG-3＇ site） that constitute the core of an ancient vertebrate TH promoter. Focusing on only eutherian mammals, two regions of high conservation within the proximal promoter were identified： a -250 bp region adjacent to the transcription start site and a -85 bp region located approximately 350 bp further upstream. Within both regions, conservation of previously reported cis-regulatory motifs and human single nucleotide variants was evaluated. Transcription reporter assays in a TH-expressing cell line demonstrated the functionality of highly conserved motifs in the proximal promoter regions and electromobility shift assays showed that brain-region specific complexes assemble on these motifs. These studies also identified a non-canonical CRE binding （CREB） protein recognition element in the proximal promoter. Together, these studies provide a detailed analysis of evolutionary conservation within the TH promoter and identify potential cisregulatory motifs that underlie a core set of regulatory mechanisms in mammals.

关键词： catecholamine dopamine transcription evolution

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：