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超重力法合成纳米碳酸钙的研究(Ⅰ)最佳反应时间的确定

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北京化工大学学报（自然科学版） 2001年第3期28卷 66-68页

作者：朱开明刘春光饶国瑛王玉红陈建峰 harm wiese 北京化工大学理学院超重力工程研究中心北京100029 德国BASF Ludwigshafen

采用红外光谱法动态跟踪研究在超重力法下合成纳米碳酸钙的整个碳化过程。实验表明 ,该方法得到的结果符合常规 pH计与电导仪记录的转化点 ,并与电镜形貌分析观察到晶形完全转化为立方型的反应时间相吻合。

关键词：超重力红外光谱法纳米碳酸钙最佳反应时间氢氧化钙乳液

Amplification process of a gas electron multiplier simulated by PIC-MCC model

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Nuclear Science and Techniques 2012年第4期23卷 203-208页

作者： harm Tolner School of Electronic Science and Engineering Southeast University Nanjing 210096China

The performance of a single gas electron multiplier(GEM) in pure Xe at an atmospheric pressure is investigated by Particle in Cell-Monte Carlo Collision(PIC-MCC) *** micro development processes with electrons and ions distributions in space have been *** on the micro development processes,the macroscopic parameters such as GEM gain and the effective efficiency have also been *** simulation results indicate that after tens of nanoseconds,electrons are collected by the readout electrode while the ions still exist in the gas space for several *** main signal current is formed by the electrons arriving at the readout electrode,but electrons and ions are also collected by the copper electrodes near the GEM hole and the thin Kapton film *** simulated gain of GEM exponentially increases with the applied GEM *** the PIC-MCC simulations,both the physical amplification and charging mechanisms in the GEM device can be well understood,which is beneficial to the device design.

关键词：气体电子倍增器模型模拟放大过程 Kapton 空间分布创业板铜电极 te模型

Polypeptide Brushes Grown via Surface-initiated Ring-opening Polymerization of α-Amino Acid N-Carboxyanhydrides

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Chinese Journal of Polymer Science 2015年第7期33卷 931-931,932-946页

作者： Yong Shen 李志波 harm-Anton Klok Laboratory of Polymer Physics and Chemistry Institute of Chemistry Chinese Academy of Sciences School of Polymer Science and Engineering Qingdao University of Science and Technology cole Polytechnique Fédérale de Lausanne (EPFL) Institut des Matériaux and Institut des Sciences et Ingénierie Chimiques Laboratoire des Polymères Batiment MXD Station 12 CH-1015 Lausanne Switzerland

Polypeptide brushes are attractive platforms to generate functional and responsive interfaces that are of potential interest due to their possible biodegradability, biocompatibility and tunable secondary structures. Surface-initiated ringopening polymerization（SI-ROP） of α-amino acid N-carboxyanhydrides represents a powerful and versatile strategy to generate polypeptide brushes. This review is an attempt to capture the state-of-the-art in this field and highlights the latest developments in several selected areas. In addition to presenting an overview of the synthetic methods that have been used to generate polypeptide brushes via SI-ROP, this article will discuss the preparation of patterned polypeptide brushes, the conformational properties of surface-tethered polypeptides, ways to control chain orientation at surfaces as well as properties and applications of these thin polymer films.

关键词： Polypeptide brushes Surface α-Amino acid N-carboxyanhydrides Ring-opening polymerization Secondary structure

Induction of desiccation tolerance in desiccation sensitive Citrus limon seeds

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Journal of Integrative Plant Biology 2019年第5期61卷 624-638页

作者： Alexandre Marques harm Nijveen Charles Somi Wilco Ligterink Henk Hilhorst Laboratory of Plant Physiology Wageningen University and ResearchWageningenThe Netherlands Bioinformatics Group Wageningen University and ResearchWageningenThe Netherlands

Many economically important perennial species bear recalcitrant seeds, including tea, coffee, cocoa, mango,citrus, rubber, oil palm and coconut. Orthodox seeds can be dried almost completely without losing viability, but so-called recalcitrant seeds have a very limited storage life and die upon drying below a higher critical moisture content than orthodox seeds. As a result, the development of longterm storage methods for recalcitrant seeds is *** this critical moisture content would be very valuable since dry seed storage is the safest, most convenient and cheapest method for conserving plant genetic ***, we have attempted to induce desiccation tolerance(DT) in the desiccation sensitive seeds of Citrus limon. We show that DT can be induced by paclobutrazol(an inhibitor of gibberellin biosynthesis) and we studied its associated transcriptome to delineate the molecular mechanisms underlying this induction of DT. Paclobutrazol not only interfered with gibberellin related gene expression but also caused extensive changes in expression of genes involved in the biosynthesis and signaling of other hormones. Paclobutrazol induced a transcriptomic switch encompassing suppression of biotic-and induction of abiotic *** hypothesize that this is the main driver of the induction of DT by paclobutrazol in C. limon seeds.

关键词： economically important recalcitrant seeds paclobutrazol in C.limon seeds

Root-derived organic matter confines sponge community composition in mangrove ecosystems

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Ecological Processes 2013年第1期2卷 139-142页

作者： Ellard R Hunting Selma M Ubels Michiel HS Kraak harm G van der Geest University of Amsterdam Aquatic Ecology and EcotoxicologyInstitute for Biodiversity and Ecosystem Dynamics(IBED-AEE)Sciencepark 904NL-1098 XHAmsterdamThe Netherlands

Introduction:Caribbean mangrove-associated sponge communities are very distinct from sponge communities living on nearby reefs,but the mechanisms that underlie this distinction remain *** has been hypothesized that dissolved organic matter(DOM)leaching from mangrove roots and the ability of mangrove-associated spongebacterial consortia to degrade mangrove DOM may cause this ***:This study tested whether mangrove DOM,leaching from mimicry substrates or directly injected in sponge tissue,affected the performance of a reef and a mangrove sponge ***:Controls and the mangrove sponge remained unaffected by mangrove DOM leaching from mimicry substrates or directly injected in sponge tissue,but the reef species showed substantial necrosis when exposed to mangrove ***:Results presented in this study suggest that mangrove DOM confines the composition of sponge communities in mangrove ecosystems,explaining the exclusion of typical reef species and the adjacent occurrence of distinct sponge communities.

关键词： Dissolved organic matter Mangrove root Necrosis Polyphenols Sponges Reef

Hepatosplenic T-cell lymphoma in a 47-year-old Crohn's disease patient on thiopurine monotherapy

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World Journal of Gastroenterology 2016年第47期22卷 10465-10470页

作者： Maartje M van de Meeberg Lauranne AAP Derikx harm AM Sinnige Peet Nooijen D Lucette Schipper Loes HC Nissen Department of Gastroenterology and Hepatology Jeroen Bosch Hospital Department of Hematology Jeroen Bosch Hospital Department of Pathology Jeroen Bosch Hospital

Hepatosplenic T-cell lymphoma(HSTCL) is a rare nonHodgkin lymphoma with a high mortality rate. Higher incidence is reported in patients with inflammatory bowel disease, specifically in male patients that are younger than 35 years, and have been treated with thiopurine and tumor necrosis factor(TNF)-α inhibitor combination therapy for over 2 years. In this case report we describe a 47-year-old patient with Crohn's disease(CD) who developed HSTCL after having been treated with thiopurine monotherapy for 14 years. To our best knowledge, only eleven cases exist of patients with CD who developed HSTCL while on thiopurine monotherapy. We report the first patient with CD, older than 35 years, who developed HSTCL while on thiopurine monotherapy. This emphasizes that HSTCL risk is not limited to young men receiving both thiopurines and TNF-α inhibitors.

关键词： Hepatosplenic T-cell lymphoma Thiopurine Crohn’s disease Immunosuppression