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Pharmacological potential of Manilkara zapota(L.)***(Sapodilla):a narrative review

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Journal of Traditional Chinese Medicine 2024年第2期44卷 403-407页

作者： Priyanka Sharma Aakash Deep harish kumar Nitin Bansal Sanjiv kumar Arun Davinder kumar Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani 127021India Department of Pharmaceutical Sciences Maharishi Dayanand UniversityRohtak 124001India

Herbal medicine is safe and effective in treating various *** herbal medicine plays a tremendous role in treatment of various diseases and accompanying complications,hence herbal medicine requires remarkable attention in further research for the development of numerous active formulations for treatment of health *** plant needs special consideration for development and research of unidentified compound and characterization of novel active molecules that overcome multiple pathological *** genus Manilkara contains 135 plants around the *** overview discusses all the virtues of most important and commonly used plant Manilkara zapota(L.)***(***),also known as *** has various traditional beneficial effects in treatment of various diseases and disorders dating back to prehistoric times and used in ancient traditional system of herbal medicine.

关键词： herbal medicine Manilkara zapota phytoconstituents pharmacological activity review

Comprehensive review on ethnomedicinal, phytochemistry and pharmacological profile of Ficus Religiosa L.

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Journal of Traditional Chinese Medicine 2024年第5期44卷 1052-1057页

作者： Rahul Rawat harish kumar Neetu Singh Aakash Deep Balasubramanian Narasimhan Surender Singh Yadav Sanjiv kumar Department of Pharmaceutical Sciences Chaudhary Bansi Lal University Department of Botany Maharshi Dayanand University Faculty of Pharmaceutical Sciences Maharshi Dayanand University

Ficus religiosa L.(F. religiosa) or sacred fig is a large perennial tree belonging to the family Moraceae or mulberry family. Though the tree has pan-tropical distribution but originally it is indigenous to the Indian subcontinent and Indochina region. Popularly the tree is named "Pepal or bodhi tree". Traditionally, it is practiced for the treatment of asthma, nose bleeding, heart disorders, diabetes, wound healing, ear problems, constipation, hyperlipidemia, gonorrhea, ulcers and infectious disorders. Chemical analysis demonstrated the presence of numerous bioactives including tannins, phenols, saponins, sugars, alkaloids, methionine, terpenoids, flavonoids, glycosides, proteins, separated amino acids, essential and volatile oils and steroids etc., which are probably responsible for its diverse pharmacological actions. The present work is an attempt to compile up-to-date comprehensive information on F. religiosa that covers its taxonomy, ethnomedicinal importance, phytochemistry, pharmacological attributes and clinical trials. Keeping in mind the various health attributes of F. religiosa, future research can be aimed at in-depth elucidation of the structure-function relationship and multifactorial signalings pathways.

关键词： Ficus religiosa clinical trials ethnomedicine health benefits pharmacology phytoconstituents

Efficient Finite Difference WENO Scheme for Hyperbolic Systems withNon-conservativeProducts

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Communications on Applied Mathematics and Computation 2024年第2期6卷 907-962页

作者： Dinshaw S.Balsara Deepak Bhoriya Chi-Wang Shu harish kumar Physics Department University of Notre DameNotre DameUSA ACMS Department University of Notre DameNotre DameUSA Division of Applied Mathematics Brown UniversityProvidenceUSA Department of Mathematics Indian Institute of TechnologyDelhiIndia

Higher order finite difference weighted essentially non-oscillatory(WENO)schemes have been constructed for conservation *** multidimensional problems,they offer a high order accuracy at a fraction of the cost of a finite volume WENO or DG scheme of the comparable *** makes them quite attractive for several science and engineering ***,to the best of our knowledge,such schemes have not been extended to non-linear hyperbolic systems with non-conservative *** this paper,we perform such an extension which improves the domain of the applicability of such *** extension is carried out by writing the scheme in fluctuation *** use the HLLI Riemann solver of Dumbser and Balsara(***.304:275-319,2016)as a building block for carrying out this *** of the use of an HLL building block,the resulting scheme has a proper supersonic *** use of anti-diffusive fluxes ensures that stationary discontinuities can be preserved by the scheme,thus expanding its domain of the *** new finite difference WENO formulation uses the same WENO reconstruction that was used in classical versions,making it very easy for users to transition over to the present *** conservation laws,the new finite difference WENO is shown to perform as well as the classical version of finite difference WENO,with two major advantages:(i)It can capture jumps in stationary linearly degenerate wave families exactly.(i)It only requires the reconstruction to be applied *** examples from hyperbolic PDE systems with non-conservative products are shown which indicate that the scheme works and achieves its design order of the accuracy for smooth multidimensional *** Riemann problems and several novel multidimensional problems that are drawn from compressible Baer-Nunziato multiphase flow,multiphase debris flow and twolayer shallow water equations are also shown to document the robustness of the *** some

关键词： Hyperbolic PDEs Numerical schemes Non-conservative products Stiff source terms Finite difference WENO

Morphological and molecular description of a new species of sandfly,Sergentomyia(Neophlebotomus)ashwanii ***.(Diptera:Psychodidae)from Western Ghats,India

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Asian Pacific Journal of Tropical Medicine 2024年第5期17卷 226-234页

作者： Prasanta Saini harish kumar Shah Mathew Jessu Sonia T Tom Anns KP Amju ICMR-Vector Control Research Centre(Field Station) KottayamKeralaIndia

Objective:To report a new species of sandfly,Sergentomyia(Neophlebotomus)ashwanii ***.(Diptera:Psychodidae)from Western Ghats,***:A systematic sandfly survey was conducted in the Thrissur and Kollam districts of Kerala,India using mechanical aspirators,light and sticky traps,both indoor and outdoor habitats,for a period of one *** acid barcoding of samples was performed targeting mitochondrial cytochrome oxidase I(COI)gene and sequence generated was subjected to phylogenetic ***:Sergentomyia(Neophlebotomus)ashwanii,a new sandfly species is recorded and described in this communication.A single row of 10-12 pointed teeth in the cibarium with 4-6 small denticles or fore-teeth are the key characteristics that is distinctive from other members of the subgenus *** COI barcode followed by phylogenetic analysis of the nucleotide sequence confirms that specimens of the species belong to the same taxonomic group while the genetic distance(14.2%)with the congeners established it to be a different ***:The Western Ghats'being an important biodiversity hotspot and has dearth of systematic entomological surveys on *** current study tried to fill the void and also report a new sandfly species.

关键词： Sergentomyia(Neophlebotomus)ashwanii COI barcode Western Ghats Phlebotomine sandflies

Recharge and vulnerability assessment of groundwater resources in North west India:Insights from isotope-geospatial modelling approach

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Geoscience Frontiers 2024年第1期15卷 247-262页

作者： Annadasankar Roy Sitangshu Chatterjee Uday kumar Sinha Anil kumar Jain Hemant Mohokar Ajay Jaryal Tirumalesh Keesari harish Jagat Pant Isotope and Radiation Application Division Bhabha Atomic Research CentreTrombayMumbai–400085India Homi Bhabha National Institute Mumbai 400094India Central Ground Water Board AhmedabadGujaratIndia

Recent studies indicate dwindling groundwater quantity and quality of the largest regional aquifer system in North West India,raising concern over freshwater availability to about 182 million population residing in this *** agricultural activities have resulted severe groundwater pollution in this area,demanding a systematic vulnerability assessment for proactive *** vulnerability assessment models encounter drawbacks due to subjectivity,complexity,data-prerequisites,and spatial-temporal *** study incorporates isotopic information into a weighted-overlay framework to overcome the above-mentioned limitations and proposes a novel vulnerability assessment *** isotope methodology provides crucial insights on groundwater recharge mechanisms(18O and 2H)and dynamics(3H)-often ignored in vulnerability *** characterisation of precipitation helped in establishing Local Meteoric Water Line(LMWL)as well as inferring contrasting recharge mechanisms operating in different *** aquifer(depth<60 m)showed significant evaporative signature with evaporation loss accounting up to 18.04%based on Rayleigh distillation ***-aquifer connections were apparent from Kernel Density Estimate(KDE)and isotope correlations.A weighted overlay isotope-geospatial model was developed combining 18O,3H,aquifer permeability,and water level *** central and northern parts of study area fall under least(0.29%)and extremely(1.79%)vulnerable zones respectively,while majority of the study area fall under moderate(42.71%)and highly vulnerable zones(55.20%).Model validation was performed using groundwater NO3-concentration,which showed an overall accuracy up to 82%.Monte Carlo Simulation(MCS)was performed for sensitivity analysis and permeability was found to be the most sensitive input parameter,followed by 3H,18O,and water *** the vulnerability map with Land Use Land Cover(LULC)and population density maps

关键词： Agricultural pollution Data scarcity Recharge mechanism Rayleigh distillation Isotope-geospatial model Vulnerability assessment

Quantum algorithms for matrix operations and linear systems of equations

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Communications in Theoretical Physics 2024年第3期76卷 100-112页

作者： Wentao Qi Alexandr I Zenchuk Asutosh kumar Junde Wu School of Mathematical Sciences Zhejiang UniversityHangzhou 310027China Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry RAS ChernogolovkaRussia P.G.Department of Physics Gaya CollegeMagadh UniversityRampurGaya 823001India harish-Chandra Research Institute HBNIChhatnag RoadJhunsiPrayagraj 211019India Vaidic and Modern Physics Research Centre Bhagal BhimBhinmalJalore 343029India

Fundamental matrix operations and solving linear systems of equations are ubiquitous in scientific *** the‘sender-receiver’model,we propose quantum algorithms for matrix operations such as matrix-vector product,matrix-matrix product,the sum of two matrices,and the calculation of determinant and inverse *** encode the matrix entries into the probability amplitudes of the pure initial states of *** applying proper unitary transformation to the complete quantum system,the desired result can be found in certain blocks of the receiver’s density *** quantum protocols can be used as subroutines in other quantum ***,we present an alternative quantum algorithm for solving linear systems of equations.

关键词： matrix operation systems of linear equations ‘sender-receiver’quantum computation model quantum algorithm

Performance Analysis of 5 G Wireless Hybrid Precoding Using Evolutionary Algorithms

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Journal of Bionic Engineering 2023年第5期20卷 2317-2330页

作者： Madhusmita Sahoo harish kumar Sahoo Department of ECE ITERSiksha O Anusandhan UniversityJagamaraBhubaneswarOdisha751030India Department of Electronics and Telecommunication Engineering Veer Surendra Sai University of TechnologyBurlaSambalpurOdisha768018India

Emerging 5G communication solutions utilize the millimeter wave(mmWave)band to alleviate the spectrum *** the mmWave range,Multiple Input Multiple Output(MIMO)technologies support a large number of simultaneous *** mmWave MIMO wireless systems,hybrid analog/digital precoding topologies provide a reduced complexity substitute for digital *** Error Rate(BER)and Spectral efficiency performances can be improved by hybrid Minimum Mean Square Error(MMSE)precoding,but the computation involves matrix inversion *** number of antennas at the broadcasting and receiving ends is quite large for mm-wave MIMO systems,thus computing the inverse of a matrix of such high dimension may not be practically *** to the need for matrix inversion and known candidate matrices,the classic Orthogonal Matching Pursuit(OMP)approach will be more *** novelty of research presented in this manuscript is to create a hybrid precoder for mmWave communication systems using metaheuristic algorithms that do not require matrix inversion *** metaheuristic approach has not employed much in the formulation of a precoder in wireless *** distinct evolutionary algorithms,such as Harris–Hawks Optimization(HHO),Runge–Kutta Optimization(RUN),Slime Mould Algorithm(SMA),Hunger Game Search(HGS)Algorithm and Aquila Optimizer(AO)are considered to design optimal hybrid precoder for downlink transmission and their performances are tested under similar practical *** to simulation studies,the RUN-based precoder performs better than the conventional algorithms and other nature-inspired algorithms based precoding in terms of spectral efficiency and BER.

关键词： Millimeter wave Hybrid precoding MIMO HHO HGS RUN SMA.AO

Comparison of wear behavior of ABS and Nylon6-Fe powder composite parts prepared with fused deposition modelling

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Journal of Central South University 2015年第10期22卷 3705-3711页

作者： harish kumar Garg Rupinder Singh Punjab Technical University Guru Nanak Dev Engineering College

Fused deposition modeling(FDM) is one of the latest rapid prototyping techniques in which parts can be manufactured at a fast pace and are manufactured with a high accuracy. This research work is carried out to study the friction and wear behavior of parts made of newly developed Nylon6-Fe composite material by FDM. This work also involves the comparison of the friction and wear characteristics of the Nylon6-Fe composite with the existing acrylonitrile butadiene styrene(ABS) filament of the FDM machine. This Is carried out on the pin on disk setup by varying the load(5, 10, 15 and 20 N) and speed(200 and 300 r/min). It is concluded that the newly developed composite is highly wear resistant and can be used in industrial applications where wear resistance is of paramount importance. Morphology of the surface in contact with the Nylon6-Fe composite and ABS is also carried out.

关键词： composite material fused deposition modeling(FDM) parts tribology pin on disc iron(Fe) Nylon 6 acrylonitrile butadiene styrene(ABS)

Adaptive Three-phase Estimation of Sequence Components and Frequency Using H∞ Filter Based on Sparse Model

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Journal of Modern Power Systems and Clean Energy 2020年第5期8卷 981-990页

作者： Umamani Subudhi harish kumar Sahoo Sanjeev kumar Mishra Department of Electronics and Telecommunication Engineering Indian Institute of Information Technology(IIIT)BhubaneshwarIndia Department of Electronics and Telecommunication Engineering Veer Surendra Sai University of Tecnology(Burla)SambalpurIndia

The estimation of sequence or symmetrical components and frequency in three-phase unbalanced power system is of great importance for protection and *** paper proposes a new H∞filter based on sparse model to track the sequence components and the frequency of three-phase unbalanced power *** inclusion of sparsity improves the error convergence behavior of estimation model and hence short-duration non-stationary PQ events can easily be tracked in the time *** proposed model is developed using l1 norm penalty in the cost function of H∞filter,which is quite suitable for estimation across all the three phases of an unbalanced *** model uses real state space modeling across three phases to estimate amplitude and phase parameters of sequence ***,frequency estimation uses complex state space modeling and Clarke transformation generates a complex measurement signal from the unbalanced three-phase *** state vector used for frequency estimation consists of two state *** proposed sparse model is tested using distorted three-phase signals from IEEE-1159-PQE database and the data generated from experimental laboratory *** analysis of absolute and mean square error is presented to validate the performance of the proposed model.

关键词： Sequence component Clarke transformation H∞filter state space model