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bla_(CTX-M),bla_(TEM),and bla_(SHV) in Enterobacteriaceae from North-Indian tertiary hospital:high occurrence of combination genes

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Asian Pacific Journal of Tropical Medicine 2011年第2期4卷 101-105页

作者： Mohammed Shahid Anuradha Singh Farrukh Sobia Mohammad Rashid Abida Malik Indu Shukla haris manzoor khan Section of Antimicrobial Agents & Drug Resistance Research and Molecular Biology Department of Medical MicrobiologyJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002Uttar PradeshIndia

Objective:To delineate the frequency of occurrence of blaCTX-M,blaTEM,and blaSHV in Enterobacteriaceae from North-Indian tertiary ***:A random collection of a subset of 45 Escherichia coli（***） and 28 Klebsiella pneumoniae（***） that was resistant to a third generation cephalosporin and obtained during 2007-2008 was selected for detailed screening for blaCTX-M,blaTEM,and blaSHV by monoplex *** isolates demonstrating the presence of blaCTX-M alleles were characterized for the specific CTX-M-genogroup by using a multiplex ***:Resistance to cefoperazone,ceftazidime,ceftriaxone,cefotaxime, cefoxitin and piperacillin was 100%each in *** isolates,whereas these resistancerates for *** isolates were 93.1%,83.8%,91.9%,93.6%,97.3%and 97.1%,respectively. Concomitant resistance to aminoglycosides,quinolones and aztreonam was also *** of any of the bla genes(blaCTX-M,blaTEM,and blaSHV) was noticed in a total of 28（38.4%） isolates of the 73 isolates *** isolates demonstrated occurrence of these genes in various ***CTX-M,blaTEM,and blaSHV were noticed in 28.8%,10.9%and 13.7%isolates, *** PCR in blaCTX-M harboring isolates demonstrated the presence of CTX-MGenogroup -1 and sequencing for the specific CTX-M-type revealed presence of CTX-M-15 type. RAPD typing showed wide diversity in ***:This is amongst the premier report describing the simultaneous occurrence of bloTEM,blaSHV,and blaampC in Indian Enterobacteriaceae and that wider dissemination of these genes,as demonstrated by diversity of isolates,raises concern and emphasizes a need for extensive search for the presence of these gene pools in Indian subcontinent.

关键词： Resistance genes blaCTX-M-15 blaTEM blaSHV Concomitant-occurrence Enterobacteriaceae

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Integration of Sequence Stratigraphic Analysis and 3D Geostatistical Modeling of Pliocene–Pleistocene Delta,F3 Block,Netherlands

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Acta Geologica Sinica(English Edition) 2023年第1期97卷 256-268页

作者： haris Ahmed khan Ali Asghar SHAHID Muhammad Jahangir khan Taher ZOUAGHI Maria Dolores ALVAREZ Syed Danial Mehdi NAQVI Hydrocarbon Development Institute of Pakistan Plot#18Street#6H-9/1IslamabadPakistan Department of Geoscience University of OsloSem Sælands vei 10371 OsloNorway Department of Earth and Environmental Sciences Bahria UniversityKarachi Campus13 National Stadium RoadKarachi-75260Pakistan Department of Geoexploration Faculty of Earth SciencesKing Abdulaziz University21589 JeddahSaudi Arabia Laboratoire de Géoressources CERTEPôle Technologique de Borj Cédria8020 SolimanTunisia Argentina's Geological and Mining Survey Aveneida General Paz 5445Edificio 25INTIGeneral San MartinArgentina

This research is focused on the analysis of the sequence stratigraphic units of F3 Block,within a wave-dominated delta of Plio–Pleistocene *** wells of F3 block and a 3D seismic data,are utilized in this *** conventional techniques of 3D seismic interpretation were utilized to mark the 11 surfaces on the seismic *** of seismic sequence stratigraphic interpretation,using well logs,and subsequent 3D geostatistical modeling,using seismic data,aided to evaluate the shallow hydrocarbon *** resulting models were obtained using System Tract and Facies models,which were generated by using sequential stimulation method and their variograms made by spherical method,moreover,these models are validated via *** CDF curve generated from upscaling of well logs using geometric method,shows a good relation with less percentage of errors(1 to 2 for Facies and 3 to 4 for System Tract models)between upscaled and raw data that complements the resulted *** approaches help us to delineate the best possible reservoir,lateral extent of system tracts(LST and/or HST)in the respective surface,and distribution of sand and shale in the *** clinoform break points alteration observed on seismic sections,also validates the sequence stratigraphic *** GR log-based Facies model and sequence stratigraphy-based System Tract model of SU-04-2 showed the reservoir characteristics,presence of sand bodies and majorly LST,respectively,mainly adjacent to the main fault of the studied ***,on the seismic section,SU-04-2 exhibits the presence of gas pockets at the same location that also complements the generated Facies and System Tract *** generated models can be utilized for any similar kind of study and for the further research in the F3 block reservoir characterization.

关键词： sequence stratigraphy facies modeling system tract modeling F3 block North Sea

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Recognition and Tracking of Objects in a Clustered Remote Scene Environment

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Computers, Materials & Continua 2022年第1期70卷 1699-1719页

作者： haris Masood Amad Zafar Muhammad Umair Ali Muhammad Attique khan Salman Ahmed Usman Tariq Byeong-Gwon Kang Yunyoung Nam Wah Engineering College University of WahWah CanttPakistan Department of Electrical Engineering University of LahoreIslamabad CampusPakistan Department of Unmanned Vehicle Engineering Sejong UniversitySeoul05006Korea Department of Computer Science HITEC University TaxilaTaxila47040Pakistan College of Computer Engineering and Sciences Prince Sattam Bin Abdulaziz UniversityAl-KhrajSaudi Arabia Department of ICT Convergence Soonchunhyang UniversityAsan31538Korea

Object recognition and tracking are two of the most dynamic research sub-areas that belong to the field of Computer *** vision is one of the most active research fields that lies at the intersection of deep learning and machine *** paper presents an efficient ensemble algorithm for the recognition and tracking of fixed shapemoving objects while accommodating the shift and scale invariances that the object may *** first part uses the Maximum Average Correlation Height(MACH)filter for object recognition and determines the bounding box *** case the correlation based MACH filter fails,the algorithms switches to a much reliable but computationally complex feature based object recognition technique i.e.,affine scale invariant feature transform(ASIFT).ASIFT is used to accommodate object shift and scale object *** extracts certain features from the object of interest,providing invariance in up to six affine parameters,namely translation(two parameters),zoom,rotation and two camera axis ***,in this paper,only the shift and scale invariances are *** second part of the algorithm demonstrates the use of particle filters based Approximate Proximal Gradient(APG)technique to periodically update the coordinates of the object encapsulated in the bounding *** the end,a comparison of the proposed algorithm with other stateof-the-art tracking algorithms has been presented,which demonstrates the effectiveness of the proposed algorithm with respect to the minimization of tracking errors.

关键词： Object racking MACH filter ASIFT particle filter recognition

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A Deep Learning Approach for Crowd Counting in Highly Congested Scene

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Computers, Materials & Continua 2022年第12期73卷 5825-5844页

作者： Akbar khan Kushsairy Abdul Kadir Jawad Ali Shah Waleed Albattah Muhammad Saeed Haidawati Nasir Megat Norulazmi Megat Mohamed Noor Muhammad haris Kaka Khel Electrical Section Universiti Kuala Lumpur British Malaysian InstituteSelangor53100Malaysia Department of Electrical Engineering International Islamic UniversityIslamabad44000Pakistan Department of Information Technology College of ComputerQassim UniversityBuraydah51452Saudi Arabia Department of Electrical Engineering National University of Computer and Emerging SciencesIslamabad44000Pakistan Computer Engineering Technology Section Universiti Kuala Lumpur Malaysian Institute of Information TechnologyKuala Lumpur50250Malaysia

With the rapid progress of deep convolutional neural networks,several applications of crowd counting have been proposed and explored in the *** congested scene monitoring,a variety of crowd density estimating approaches has been *** understanding of highly congested scenes for crowd counting during Muslim gatherings of Hajj and Umrah is a challenging task,as a large number of individuals stand nearby and,it is hard for detection techniques to recognize them,as the crowd can vary from low density to high *** deal with such highly congested scenes,we have proposed the Congested Scene Crowd Counting Network(CSCC-Net)using VGG-16 as a core network with its first ten layers due to its strong and robust transfer learning rate.A hole dilated convolutional neural network is used at the back end to widen the relevant field to extract a large range of information from the image without losing its original *** dilated convolution neural network is mainly chosen to expand the kernel size without changing other ***,several loss functions have been applied to strengthen the evaluation accuracy of the ***,the entire experiments have been evaluated using prominent data sets namely,ShanghaiTech parts A,B,UCF_CC_50,and UCF_*** model has achieved remarkable results i.e.,68.0 and 9.0 MAE on ShanghaiTech parts A,B,199.1 MAE on UCF_CC_50,and 99.8 on UCF_QNRF data sets respectively.

关键词： Deep learning congested scene crowd counting fully convolutional neural network dilated convolution

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Experimental Evaluation of Trilateration-Based Outdoor Localizationwith LoRaWAN

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计算机、材料和连续体（英文） 2023年第4期75卷 845-862页

作者： Saeed Ahmed Magsi Mohd haris Bin Md Khir Illani Bt Mohd Nawi Muath Al Hasan Zaka Ullah Fasih Ullah khan Abdul Saboor Muhammad Aadil Siddiqui Department of Electrical and Electronic Engineering Universiti Teknologi PETRONASSeri Iskandar32610Malaysia Balochistan University of Information Technology Engineeringand Management SciencesQuetta37500Pakistan College of Engineering Al Ain UniversityAl Ain64141United Arab Emirates Department of Technology The University of LahoreLahore54000Pakistan High Performance Cloud Computing Centre(HPC3) Universiti Teknologi PETRONASSeri Iskandar32610Malaysia

Long Range Wide Area Network (LoRaWAN) in the Internet ofThings (IoT) domain has been the subject of interest for researchers. Thereis an increasing demand to localize these IoT devices using LoRaWAN dueto the quickly growing number of IoT devices. LoRaWAN is well suited tosupport localization applications in IoTs due to its low power consumptionand long range. Multiple approaches have been proposed to solve the localizationproblem using LoRaWAN. The Expected Signal Power (ESP) basedtrilateration algorithm has the significant potential for localization becauseESP can identify the signal’s energy below the noise floor with no additionalhardware requirements and ease of implementation. This research articleoffers the technical evaluation of the trilateration technique, its efficiency,and its limitations for the localization using LoRa ESP in a large outdoorpopulated campus environment. Additionally, experimental evaluations areconducted to determine the effects of frequency hopping, outlier removal, andincreasing the number of gateways on localization accuracy. Results obtainedfrom the experiment show the importance of calculating the path loss exponentfor every frequency to circumvent the high localization error because ofthe frequency hopping, thus improving the localization performance withoutthe need of using only a single frequency.

关键词： LoRaWAN localization expected signal power(ESP) path loss exponent(PLE) trilateration

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Influence of Filler on the Microstructure, Mechanical Properties and Residual Stresses in TIG Weldments of Dissimilar Titanium Alloys

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Acta Metallurgica Sinica(English Letters) 2021年第10期34卷 1395-1406页

作者： Massab Junaid Fahd Nawaz khan Tauheed Shahbaz haris saleem Julfikar Haider Faculty of Mechanical Engineering Ghulam Ishaq Khan Institute of Engineering Sciences and TechnologyTopi 23640Pakistan Faculty of Materials and Chemical Engineering Department of Materials ScienceGhulam Ishaq Khan Institute of Engineering Sciences and TechnologyTopi 23640Pakistan Advanced Materials and Surface Engineering(AMSE)Research Centre Manchester Metropolitan UniversityChester StreetManchester M15GDUK

The influence of titanium alloy(Ti–5 Al–2.5 Sn) and commercially pure titanium(cp Ti) as fillers on dissimilar pulsed tungsten inert gas weldments of Ti–5 Al–2.5 Sn/cp Ti was investigated in terms of microstructure, mechanical/nano-mechanical properties, and residual stresses. A partial martensitic transformation was observed in the weldments for all the welding conditions due to high heat input. The microstructure evolved in the FZ/cp Ti interfacial region was observed to be the most sensitive to the proportion of α stabilizer in the filler alloy. Furthermore, the addition of filler alloy improved the tensile properties and nano-mechanical response of the weld joint owing to the increased volume of metal in the weld joint. As compared to the Ti–5 Al–2.5 Sn wire, the use of cp Ti filler wire proved to be better in terms of energy absorbed during tensile and impact tests, tensile strength and ductility of the dissimilar welds. An asymmetrical residual stresses profile was observed close to the weld centerline, with high compressive stresses on the Ti–5 Al–2.5 Sn side for both the weldments obtained with and without filler wires. This was attributed to mainly the low thermal conductivity of Ti–5 Al–2.5 Sn. The presence of residual stresses also influenced the nano-hardness profile across the weldments.

关键词： Titanium alloys Dissimilar welding Nano-indentation Residual stresses Tungsten inert gas(TIG)welding Microstructure

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Multifaceted Strategies Used by Root-Knot Nematodes to Parasitize Plants-A Review

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Phyton-International Journal of Experimental Botany 2020年第2期89卷 205-215页

作者： Adnan Shakeel Abrar Ahmad khan Mohammad haris Division of Environmental Botany Department of BotanyAligarh Muslim UniversityAligarh202002India

Root-knot nematodes being omnipresent in agricultural and horticultural soils are tallied among the most important economic pathogens around the *** successful parasitism,these nematodes use various strategies to control and manipulate the host plant’s cell *** strategies include the mole-cular mimicry of some host genes by some nematode secreted effector proteins,secretion of cell wall digesting enzymes and other effector proteins that are responsible for the suppression of defence by the host *** these secretions which are released through the stylet,contribute to the formation of specialized feeding sites or giant *** effector proteins interfere with the normal physiology,cytology and biochemistry of the host *** present review brings novel insights by summarizing some novel effectors that have been discovered recently like MgPDI,MiMIF,MiIDL1,MiISE6,Mg16820,*** also discusses some novel mechanisms through which these effector proteins target different pathways of host plants and thus facilitate nematode parasitism.

关键词： Effector proteins meloidogyne parasitism mimicry

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In vivo immunomodulatory profile of histamine receptors(H1,H2,H3 and H4):a comparative antagonists study

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Asian Pacific Journal of Tropical Medicine 2010年第6期3卷 465-470页

作者： Trivendra Tripathi Mohammad Shahid haris M khan Aijaz Ahmed khan Mashiatullah Siddiqui Rahat Ali khan Department of Biochemistry Faculty of MedicineJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002U.P.India Department of Microbiology Faculty of MedicineJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002U.P.India Department of Anatomy Faculty of MedicineJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002U.P.India Department of Pharmacology Faculty of MedicineJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002U.P.India

Objective:To delineate the comparative immunomodulatory roles of H1R-H4R in antibody generation profile in rabbit ***:The cohort comprised of eight groups containing 18(9 male and 9 female) rabbits in each ***Ⅰremained non-immunized and received only vehicle(sterile distilled water,1 mL/kg×b.i.d.) ***Ⅱreceived vehicle (1 mL/kg×b.i.d.) while GroupsⅢ-Ⅶ(drugs-treated) received subcutaneous histamine (100μg/kg×b.i.d.),and intramuscular H1R-antagonist(pheniramine,10 mg/kg×b.i.d.), H2R-antagonist(ranitidine,10 mg/kg×b.i.d.),H3R-antagonist(iodophenpropit,1μg/kg×b.i.d.) and H4R-antagonist(JNJ 7777120,10μg/kg×b.i.d.),and GroupⅧDMSO(1 mL/kg×b.i.d.),respectively for 10 days(starting from day 1).They were subsequendy immunized with intravenous injection of sheep red blood cells(SRBC) at day *** estimation of serum Igs,IgM and IgG were done by ELISA,and observed at day 0(pre-immunization),and 7,14,21,28 and 58(post-immunization).Results:It was shown that histamine and HRs-antagonists could influence a detectable antibody response to SRBC as early as day 7-post-immunization(post-Ⅰ), which lasted until day 58 post-Ⅰ.The results were found statistically significant(P<0.05,). Conclusions:This study suggests that histamine receptors play important roles in modulation of antibody generation in which H1R,H2R and H4R have immunosuppressive roles and conversely, H3R playes an immune enhancing *** findings of this study may have clinical significance and provide the baseline information for future study.

关键词： Histamine receptors Immunomodulation Humoral immune response H3R-antagonist H4R-antagonist

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Changing trends in prevalence of different Plasmodium species with dominance of Plasmodium falciparum malaria infection in Aligarh(India)

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Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 64-66页

作者： haris M khan Fatima Shujatullah Mohammad Ashfaq Adil Raza Department of Microbiology J.N.Medical College and HospitalA.M.U.Aligarh

Objective:To determine the prevalence of malaria in Aligarh and analyze species dominance in different years over a ***:Diagnosis of malaria was done using microscopy as gold standard,rapid antigen detection assays and quantitative buffy coat(QBC) *** stained blood smear examination was done,thick and thin films were examined for presence of different Plasmodium *** antigen detection assays employing detection of HRP-2 and parasite lactate dehydrogenase antigen(pLDH) by immunochromatography was done in patients whose blood smear found to be negative by conventional Giemsa slide *** was done in cases where there is strong clinical suspicion of malaria with blood smear negative,in patients with chronic malaria,splenomegaly,or in those patients who had inadequate treatment and for post-treatment follow ***:Plasmodium vivax and Plasmodium falciparum were only species detected in our *** prevalence of malaria in Aligarh was found to be 8.8%.The maximum prevalence of 20.1%was observed in year 2008 and lowest 2.3%in 2002. Conclusions:High prevalence of malaria is observed in this part of country with dominance of both species particularly Plasmodium falciparum should be monitored and factors accounting for occurrence should be studied to employ effective control measures.

关键词： Plasmodium falciparum Prevalence Dominance Malaria

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Comparative study on occurrence of class A and class Cβ-lactamase genes and their co-occurrence in Indian Enterobacteriaceae during years 2009 and 2010

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Asian Pacific Journal of Tropical Medicine 2011年第10期4卷 764-768页

作者： Anuradha Singh Mohd Shahid Farrukh Sobia Umesh haris M khan Section of Antimicrobial Agents & Drug Resistance Research and Molecular Biology Department of MicrobiologyJawaharlal Nehru Medical College & HospitalAligarh Muslim UniversityAligarh-202002Uttar PradeshIndia Department of Medical Microbiology Immunologyand Infectious DiseasesCollege of Medicine & Medical SciencesArabian Gulf UniversityKingdom of Bahrain Department of Microbiology Government Medical CollegeHaldwaniUttrakhandIndia

Objective:To determine the occurrence of class A and class Cβ-Iactamase genes and their cooccurrence in Indian ***:52 third generation cephalosporin resistant isolates were phenotypically detected by combination disk method and screened by PCR to identify class A and class C typeβ-lactamase ***:Of the 52 isolates,94.2%（49） were found harboring any of the bla?,blaCTX-M,blaSHV and blaTEM were present in 82.6%（43/52）, 59.6%（31/52）,and 42.3%（22/52） isolates,*** the 49 ESBL positive isolates 57.1% （28/49） showed co-occurrence of blaampCwith bla?.On the contrary,the collection from 2009 showed their co-occurrence in 81.4%***:The comparative study shows a downward trend for co-existence of bla? with blaampC from 2009 to *** large scale studies are needed to address the co-occurrence of class A and class Cβ-lactamases in India and the resistance trend occurring over a period of time.

关键词： Class A ESBL Class C ESBL CTX-M AmpC Enterobacteriaceae India

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