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An unexpected cellular fountain of youth:platelets provide factors rejuvenating brain functions

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signal Transduction and Targeted Therapy 2024年第1期9卷 16-18页

作者： harald F.Langer Department of Cardiology AngiologyHaemostaseology and Medical Intensive CareUniversity Medical Centre MannheimMedical Faculty MannheimHeidelberg UniversityMannheimGermany German Centre for Cardiovascular Research(DZHK) Partner Site Heidelberg/MannheimMannheimGermany European Center for Angioscience Medical Faculty MannheimHeidelberg UniversityMannheimGermany Cardiovascular systems biology Medical Clinic IUniversity Heart Center LübeckLübeckGermany

In a recent manuscript published in Nature,schroer et *** that platelets and in particular platelet derived PF-4(CXCL4)are a novel factor,which can rejuvenate the mammalian neuronal system.1 These findings have the potential to trigger an entire new field of research opening new platelet-derived candidate effector molecules for supporting regeneration.

关键词： supporting platelets finding

Effect of slag basicity on Alumina Dissolution and Diffusivity:A High-temperature Confocal Laser scanning Microscopy study

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China's Refractories 2024年第2期33卷 27-34页

作者： burhanuddin harald HARMUTH Montanuniversität Leoben Leoben 8700Austria

Alumina is one of the crucial and extensively utilized refractory *** the refractory wear due to dissolution at elevated temperatures during operation is a major threat to refractory lifespan,quantifying dissolution is important for developing cost-effective and resource-efficient *** study investigated the dissolution of alumina particles in two silicate and one calcium aluminate slags at 1450,1500,and 1550°C using high-temperature confocal laser scanning microscopy(HT-CLsM).Dissolution was quantified in terms of diffusivity,with all influencing factors,including stefan flow and bath movement,incorporated into the determination *** trends observed in total dissolution time and diffusivity in three slags at three experimental temperatures could not be explained solely on the basis of slag *** parameters,considering the influencing factors,were introduced to explain these ***,the linear trend observed in Arrhenius plots of diffusivities supports the diffusivity ***,good agreement between the diffusivities of alumina in one silicate slag obtained via CLsM and rotating finger test investigations verified the reliability of the results.

关键词： alumina dissolution diffusivity corrosion refractory

从模型到应用:基于生态系统服务权衡的乡村生态修复规划工具研究

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园林 2024年第3期41卷 4-12页

作者：董楠楠王怡琪 harald Zepp Lars Gruenhagen Malte bührs Christin busch 魏维轩同济大学建筑与城市规划学院上海200092 波鸿鲁尔大学地理学系波鸿44801 ILs-国家和城市发展研究所有限公司多特蒙德D-44135

在全球范围内的气候变化背景下,具有多种功能和服务价值的乡村生态空间成为当下国际生态规划研究与合作的关注热点之一。为实现乡村生态空间的精准管理与规划,中德双方围绕联合课题“生态系统服务概念在德国鲁尔与中国大都市区韧性发展... 详细信息

在全球范围内的气候变化背景下,具有多种功能和服务价值的乡村生态空间成为当下国际生态规划研究与合作的关注热点之一。为实现乡村生态空间的精准管理与规划,中德双方围绕联合课题“生态系统服务概念在德国鲁尔与中国大都市区韧性发展模式下的绿色基础设施规划应用”进行了深入探索。在土地利用与土地覆盖类型的基础上,进一步识别了生物群落类型,并基于调节、供给、文化三大生态系统服务类型,选取了评估生态系统服务供需权衡的指标和对应权重,构建了乡村生态空间规划场景下的生态系统服务价值评测模型。以上海市水库村为例,运用该课题的评测模型,初步评估了典型乡村生态规划场景下的生态系统服务价值。最后,从应用尺度、研究范围以及操作流程三个方面总结了该评测模型的优化方向。

关键词：乡村生态修复生态系统服务供需权衡决策辅助工具

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Will Germany move into a situation with unsecured power supply?

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Frontiers in Energy 2019年第3期13卷 551-570页

作者： harald sCHWARZ Energy Distribution and High Voltage Engineering Faculty 3Brandenburg University of TechnologyCottbus-Senftenberg 03013Germany

Together with a huge number of other countries, Germany signed the Paris Agreements in 2015 to prevent global temperature increase above 2℃. Within this agreement, all countries defined their own national contributions to CO2 reduction. since that, it was visible that CO2 emissions in Germany decreased, but not so fast than proposed in this German nationally determined contribution to the Paris Agreement. Due to increasing traffic, CO2 emissions from this mobility sector increased and CO2 emission from German power generation is nearly constant for the past 20 years, even a renewable generation capacity of 112 GW was built up in 2017, which is much higher than the peak load of 84 GW in Germany. That is why the German National Government has implemented a commission (often called "The German Coal Commission") to propose a time line: how Germany can move out of coal-fired power stations. This "Coal Commission" started its work in the late spring of 2018 and handed over its final report with 336 pages to the government on January 26th, 2019. Within this report the following proposals were made:①Until 2022: Due to a former decision of the German Government, the actual remaining nuclear power generation capacity of about 10 GW has to be switched off in 2022. besides, the "Coal Commission" proposed to switch off additionally in total 12.5 GW of both, hard coal and lignite-fired power plants, so that Germany should reduce its conventional generation capacity by 22.5 GW in 2022.②Until 2030: Another 13 GW of German hard coal or lignite-fired power plants should be switched off.③Until 2038:The final 17 GW of German hard coal or lignitefired power plants should be switched off until 2038 latest. Unfortunately the "Coal Commission" has not investigated the relevant technical parameter to ensure a secured electric power supply, based on German's own national resources. because German Energy Revolution mainly is based on wind energy and photovoltaic, this paper will describe the

关键词： CO2 reduction mobility sector renewable generation coal commission secured power generation capacity reliable power supply power-to-gas power-to-heat

Effects of the switching time in OPs/Obs networks

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Chinese Optics Letters 2004年第3期2卷 131-134页

作者： harald Qverby Norvald stol Department of Telematics Norwegian University of Science and TechnologyO. S. Bragstadsplass 2E N-7491 Trondheim Norway

In this paper we present an analytical model, which considers the effects of the switching time on the network performance in service differentiated optical packet/burst switching (OPs/Obs) networks. Our results indicate that the switching time must be less than 10 % of the packet/burst duration in order to avoid any significant reductions in the network performance. Furthermore, regarding a network with full wavelength conversion, we show that the benefits of statistical resource sharing are almost non-existent for low priority traffic when the switching time is large.

关键词： Obs time OPs

A study on adjusted contact force laws for accelerated large scale discrete element simulations

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Particuology 2010年第2期8卷 161-175页

作者： harald Kruggel-Emden Frantisek stepanek Ante Munjiza Department of Chemical Engineering South Kensington Campus Imperial College London SW7 2AZ London UK Department of Engineering Queen Mary University of London Mile End Road E1 4NS London UK

The aim of this work is to systematically investigate the effect of the normal force law and the applied stiff- ness on the behavior of single particles and particle systems. A detailed review of the literature regarding altered stiffnesses and their use in force laws is provided, The effect on macroscopic simulation properties such as contact numbers, velocity profiles, discharge rates and quality of dispersion for different fractions of maximum overlap is studied in the case of a stirrer vessel and a rectangular hopper. In order to provide further acceleration beyond the limits imposed by classical force models, a number of alternative force laws are developed which have a more favorable ratio between contact time and maximal overlap. Their employment in large scale simulations is investigated in light of their applicability. some of the suggested force law modifications reveal artificial characteristics requiring further alteration. 2009 Chinese society of Particuology and Institute of Process Engineering, Chinese Academy of sciences. Published by Elsevier b.V. All rights reserved.

关键词： Large scale simulationsContact force modelsDiscrete Element MethodstiffnessParticle overlap

Wireless data transmission using visual codes

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Photonics Research 2014年第5期2卷 150-160页

作者： Thilo Fath Falk schubert harald Haas Institute for Digital Communications University of EdinburghEH93JL EdinburghUK Innovation Works Germany EADS Deutschland GmbH81663 MunichGermany

In this paper,a new approach for wireless data transmission within an aircraft cabin is *** proposed application enables the transmission of data to a passenger’s user *** wireless in-flight applications are subject to strict frequency and electromagnetic compatibility(EMC)regulations,the data is transferred by optical wireless transmission,specifically by two-dimensional visual *** this end,black-and-white or colored visual code sequences are displayed on the in-flight entertainment *** visual codes are captured by the built-in camera of the passenger’s mobile device and are decoded to reconstruct the transmitted *** order to compensate for frame losses caused by effects like occlusion and motion blur,a temporal forward error correction coding scheme is *** experiments within an Airbus A330 cabin mock-up demonstrate the functionality of the implemented system under realistic conditions such as ambient illumination and geometric *** user devices are used for evaluation;specifically,a low-cost and a high-end smartphone are employed as *** evaluations show that the proposed transmission system achieves data rates of up to 120 kbit/s per individual passenger seat with these user *** the user device has no physical connection to the sensitive on-board system,the proposed transmission system provides an intrinsic safety feature.

关键词： visual illumination correction

Leaching of decabromodiphenyl ether and hexabromocyclododecane from fabrics under simulated landfill conditions

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Emerging Contaminants 2020年第1期6卷 33-38页

作者： stuart Harrad Daniel s.Drage Martin sharkey harald berresheim school of Geography Earth and Environmental SciencesUniversity of BirminghamBirminghamB152TTUK school of Physics National University of Ireland GalwayGalwayIreland

A series of laboratory experiments were conducted to examine the leaching of decabromodiphenyl ether(bDE-209)and hexabromocyclododecane(HbCDD)from a mix of three *** with previous reports that such leaching is governed by second order kinetics,concentrations in leachate were markedly higher in the first 24 h of leaching,and diminished by an order of magnitude after 1 *** influence of the waste:leachate ratio was examined for the first time,with leaching of both bDE-209 and HbCDD significantly greater(pste:leachate ratio of 0.005 g/mL than at 0.05 g/*** dissolved humic matter(DHM)solutions as proxy for simulating organic landfill leachates we found that leaching of both bDE-209 and HbCDD was also significantly greater at a DHM concentration of 1,000 mg/L in leachate compared to that observed at DHM values of 100 and 0 mg/*** of waste:leachate mixtures significantly enhanced *** leaching of HbCDD decreased significantly as leachate pH increased from 5.8,through 6.5,to 8.5;no significant impact of pH on leaching of bDE-209 was *** in leachate of both bDE-209 and HbCDD decreased significantly on increasing leachate temperature from 20℃to 60℃and 80℃.This is considered most likely due to volatilisation of these contaminants into the headspace of the leaching vessel at higher temperatures.

关键词： brominated flame retardants Leachate pH Organic matter content Temperature waste:leachate ratio

Halton-type sequences from global function fields

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science China Mathematics 2013年第7期56卷 1467-1476页

作者： NIED ERREITER harald YEO Anderson siangJing Johann Radon Institute for Computational and Applied Mathematics Austrian Academy of Sciences Department of Mathematics University of Salzburg school of Physical and Mathematical sciences Nanyang Technological University

For any prime power q and any dimension s≥1, a new construction of (t, s)-sequences in base q using global function fields is presented. The construction yields an analog of Halton sequences for global function fields. It is the first general construction of (t, s)-sequences that is not directly based on the digital method. The construction can also be put into the framework of the theory of (u, e, s)-sequences that was recently introduced by Tezuka and leads in this way to better discrepancy bounds for the constructed sequences.

关键词： low-discrepancy sequence (t s)-sequence Halton sequence global function field