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靶向嗅觉蛋白的植物精油源潜在昆虫行为控制剂研究进展

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农药学学报 2024年第4期26卷 647-664页

作者：朱文亚朱紫薇傅浩宇梁馨月段红霞中国农业大学理学院应用化学系农药创新中心林草有害生物药剂防治国家林业和草原局重点实验室北京100193

昆虫具有敏锐且复杂的嗅觉系统,这一系统的运行离不开多种嗅觉蛋白的参与。嗅觉蛋白可以通过对外界气味分子的捕获、运输、识别和降解,进而调控昆虫的取食、交配、繁殖、报警等一系列生理行为。本文综述了昆虫嗅觉蛋白中的气味结合蛋白(... 详细信息

昆虫具有敏锐且复杂的嗅觉系统,这一系统的运行离不开多种嗅觉蛋白的参与。嗅觉蛋白可以通过对外界气味分子的捕获、运输、识别和降解,进而调控昆虫的取食、交配、繁殖、报警等一系列生理行为。本文综述了昆虫嗅觉蛋白中的气味结合蛋白(OBPs)和嗅觉受体(ORs)在调控昆虫行为上的功能及其晶体结构研究进展,并根据已报道的气味结合蛋白或嗅觉受体与配体小分子的共晶结构,重点分析了二者的互作模式。同时以植物精油为代表,介绍了其在调控昆虫行为活性方面的研究进展,期望为以昆虫气味结合蛋白或嗅觉受体为潜在靶标,聚焦新颖的天然植物精油源先导结构,开发新型的昆虫行为控制剂提供参考。

关键词：嗅觉蛋白气味结合蛋白嗅觉受体反向化学生态学植物精油昆虫行为控制剂

Horizontal Well Interference Performance and Water Injection Huff and Puff Effect on Well Groups with Complex Fracture Networks:A Numerical Study

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2285-2309页

作者： haoyu fu Hua Liu Xiaohu Hu Lei Wang State Key Laboratory of Shale Oil and Gas EnrichmentMechanisms and Effective Development SINOPECBeijing100101China Sinopec Key Laboratory of Shale Oil/Gas Exploration and Production Technology SINOPECBeijing100083China Key Laboratory of Tectonics and Petroleum Resources Ministry of EducationChina University of GeosciencesWuhan430074China

Well interference has become a common phenomenon with the increasing scale of horizontal well *** studies on well interference in horizontal wells do not properly reflect the physical model of the postfracturing well groups and the realistic fracturing process of infill *** the correspondence between well interference causative factors and manifestations is of great significance for infill well deployment and secondary oil *** this work,we develop a numerical model that considers low velocity non-Darcy seepage inshale reservoirs to study the inter-well interferencephenomenon that occurs in theSantanghufield,andconstruct an explicit hydraulic fracture and complex natural fracture network model with an embedded discrete fracture model,focusing on the effect of fracture network morphology on well *** model also considers a multi-segment wellbore model to accommodate the effect of inter-well crossflow on wellbore tubular *** changes in formation pressure and water saturation during fracturing are performed by controlling the injection pressure and water injection *** result shows that the shape of the fracture network generated by the infill well with the old well determines the subsequent fluid and oil-increasing performance of the disturbed *** synergistic production or competitive relationship formed by fractures with different connectivity between the two wells determines the positive and negative effects of the *** paper also investigates the adaptation study of water injection huff and puff schemes for well groups with different connectivity,and demonstrated a potential yield increase of up to 10.85%under adaptation *** method of identifying well interference based on the production dynamics of affected wells and the subsequent corresponding water injection method provides valuable references for the selection of secondary oil recovery measures.

关键词： Unconventional reservoirs well interference embedded discrete fracture model water injection huff and puff complex fracture networks

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基于无监督学习的连铸铸坯缺陷检测方法

重型机械 2024年第3期 32-40页

作者：高琦付皓宇吴晓军柴玮米进周中国重型机械研究院股份公司陕西西安710018 西安交通大学软件学院陕西西安710049

铸坯在连铸过程中受温度分布不均、流动速度不稳等多种因素的影响,容易出现各种表面和内部缺陷,如疏松、偏析、缩孔、裂纹、气泡、夹杂等。这些缺陷不仅影响产品的外观和性能,还可能对工程结构的安全性产生潜在威胁。针对这一问题,提出... 详细信息

铸坯在连铸过程中受温度分布不均、流动速度不稳等多种因素的影响,容易出现各种表面和内部缺陷,如疏松、偏析、缩孔、裂纹、气泡、夹杂等。这些缺陷不仅影响产品的外观和性能,还可能对工程结构的安全性产生潜在威胁。针对这一问题,提出了一种基于无监督学习的连铸铸坯缺陷检测方法,该方法利用图像频域处理技术和深度学习算法学习连铸铸坯正常样本的图像特征,通过图像重建方式自动检测铸坯图像中的缺陷。首先,通过频率解耦模块对铸坯图像进行图像频率分离,得到铸坯的低频图像与高频图像。然后,采用带有自监督预测卷积注意模块的生成器网络集合,分别重建低频图像和高频图像。最后,通过判别器网络对铸坯的原始图像与重建图像进行判定,以确定铸坯图像中是否包含缺陷。实验结果表明,该方法能够有效检测连铸铸坯的缺陷,具有较高的准确性和可靠性,可为提高连铸产品质量和生产效率提供有力支持。

关键词：连铸铸坯缺陷检测无监督学习频域处理

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The anisotropy of suprathermal electrons in the Martian ionosphere

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Earth and Planetary Physics 2024年第3期8卷 459-471页

作者： YuTian Cao Jun Cui XiaoShu Wu WenJun Liang RuiQi fu haoyu Lu Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai 519082China Key Laboratory of Geospace Environment University of Science&Technology of ChinaChinese Academy of SciencesHefei 230026China Center for Excellence in Comparative Planetology Chinese Academy of SciencesHefei 230026China School of Space and Environment Beihang UniversityBeijing 102206China

Suprathermal electrons are an important population of the Martian ionosphere, either produced by photoionization of atmospheric neutrals or supplied from the Solar Wind (SW). This study is dedicated to an in-depth investigation of the pitch angle distribution of suprathermal electrons at two representative energies, 19−55 eV and 124−356 eV, using the extensive measurements made by the Solar Wind Electron Analyzer on board the Mars Atmosphere and Volatile Evolution. Throughout the study, we focus on the overall degree of anisotropy, defined as the standard deviation of suprathermal electron intensity among different directions which is normalized by the mean omni-directional intensity. The available data reveal the following characteristics: (1) In general, low energy electrons are more isotropic than high energy electrons, and dayside electrons are more isotropic than nightside electrons;(2) On the dayside, the anisotropy increases with increasing altitude at low energies but remains roughly constant at high energies, whereas on the nightside, the anisotropy decreases with increasing altitude at all energies;(3) Electrons tend to be more isotropic in strongly magnetized regions than in weakly magnetized regions, especially on the nightside. These observations indicate that the anisotropy is a useful diagnostic of suprathermal electron transport, for which the conversion between the parallel and perpendicular momenta as required by the conservation of the first adiabatic invariant, along with the atmospheric absorption at low altitudes, are two crucial factors modulating the observed variation of the anisotropy. Our analysis also highlights the different roles on the observed anisotropy exerted by suprathermal electrons of different origins.

关键词： Mars ionosphere suprathermal electron pitch angle distribution

合成聚合物衍生硬碳在钠离子电池中的研究进展

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天津大学学报（自然科学与工程技术版） 2022年第1期55卷 11-23页

作者：李瑀付浩宇封伟天津大学材料科学与工程学院天津300072

在过去的10年里,便携式电子设备和电动汽车的迅速发展引起了人们对电化学储能系统商业化的兴趣.因钠元素在地球上的丰富储备,钠离子电池是目前锂离子电池最有前途的替代品,作为一种新兴的低成本储能技术,在大规模电化学储能中具有较好... 详细信息

在过去的10年里,便携式电子设备和电动汽车的迅速发展引起了人们对电化学储能系统商业化的兴趣.因钠元素在地球上的丰富储备,钠离子电池是目前锂离子电池最有前途的替代品,作为一种新兴的低成本储能技术,在大规模电化学储能中具有较好的应用前景.由于碳材料的原料丰富、成本低廉、具有低的电化学电位,通常是电池负极材料的首选.其中,石墨具备良好的化学稳定性和相对较高的比容量被广泛用于商业锂离子电池.但是由于热力学的限制,钠与石墨的层间化合物不存在,将石墨作为钠离子电池的负极几乎不显示储钠活性,这导致容量的极大损失.硬碳具有可膨胀的石墨烯夹层、合适的工作电压和相对较低的成本,被认为是最有可能实现商业化应用的钠离子电池负极材料.合成聚合物作为硬碳前驱体的重要来源,可以通过调控化学组成结构和工艺条件,实现不同的结构和形貌,以满足不同的性能需求.本文综述了近年来以合成聚合物为前驱体制备硬碳负极材料的研究进展,重点介绍了合成聚合物的种类和制备方法对硬碳材料的微观结构形态的影响,以及形貌结构和电化学性能之间的关系.此外,还探讨了提升硬碳材料电化学性能的关键因素,并提出了未来主要发展的方向,促进钠离子电池实现商业化.

关键词：合成聚合物硬碳钠离子电池储钠机理研究进展

Fluorinated graphene nanoribbons from unzipped single-walled carbon nanotubes for ultrahigh energy density lithium-fluorinated carbon batteries

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Science China Materials 2021年第6期64卷 1367-1377页

作者： Cong Peng Lingchen Kong Yu Li haoyu fu Lidong Sun Yiyu Feng Wei Feng School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional MaterialsKey Laboratory of Advanced Ceramics and Machining TechnologyMinistry of EducationTianjin UniversityTianjin 300354China

Lithium-fluorinated carbon(Li-CFx)batteries have become one of the most widely applied power sources for high energy density applications because of the advantages provided by the CFx ***,the large gap between the practical and theoretical potentials alongside the stoichiometric limit of commercial graphite fluorides indicates the potential for further energy ***,monolayer fluorinated graphene nanoribbons(F-GNRs)were fabricated by unzipping single-walled carbon nanotubes(SWCNTs)using pure F2 gas at high temperature,which delivered an unprecedented energy density of 2738.45 W h kg^(−1)due to the combined effect of a high fluorination degree and discharge plateau,realized by the abundant edges and destroyed periodic structure,***,at a high fluorination temperature,the theoretical calculation confirmed a zigzag pathway of fluorine atoms that were adsorbed outside of the SWCNTs and hence initiated the spontaneous process of unzipping SWCNTs to form the monolayer *** controllable fluorination of SWCNTs provided a feasible approach for preparing CFx compounds for different applications,especially for ultrahigh-energy-density cathodes.

关键词： fluorinated graphene nanoribbons unzipped singlewalled carbon nanotubes ultrahigh energy density lithiumfluorinated carbon batteries

Single-cell transcriptome analysis dissects lncRNA-associated gene networks in Arabidopsis

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Plant Communications 2024年第2期5卷 94-105页

作者： Zhaohui He Yangming Lan Xinkai Zhou Bianjiong Yu Tao Zhu Fa Yang Liang-Yu fu haoyu Chao Jiahao Wang Rong-Xu Feng Shimin Zuo Wenzhi Lan Chunli Chen Ming Chen Xue Zhao Keming Hu Dijun Chen State Key Laboratory of Pharmaceutical Biotechnology School of Life SciencesNanjing UniversityNanjing 210023China Department of Bioinformatics College of Life SciencesZhejiang UniversityHangzhou 310058China Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding/Key Laboratory of Plant functional Genomics of the Ministry of Education College of AgricultureYangzhou UniversityYangzhou 225009China Co-Innovation Center for Modern Production Technology of Grain Crops of Jiangsu Province/Key Laboratory of Crop Genetics and Physiology of Jiangsu Province Yangzhou UniversityYangzhou 225009China Zhejiang Zhoushan High School Zhoushan 316099China National Key Laboratory for Germplasm Innovation and Utilization for Fruit and Vegetable Horticultural Crops Hubei Hongshan LaboratoryWuhan 430070China

The plant genome produces an extremely large collection of long noncoding RNAs(lncRNAs)that are generally expressed in a context-specific manner and have pivotal roles in regulation of diverse biological ***,we mapped the transcriptional heterogeneity of lncRNAs and their associated gene reg-ulatory networks at single-cell *** generated a comprehensive cell atlas at the whole-organism level by integrative analysis of 28 published single-cell RNA sequencing(scRNA-seq)datasets from juvenile Arabidopsis *** then provided an in-depth analysis of cell-type-related lncRNA signatures that show expression patterns consistent with canonical protein-coding gene *** further demon-strated that the cell-type-specific expression of lncRNAs largely explains their tissue *** addi-tion,we predicted gene regulatory networks on the basis of motif enrichment and co-expression analysis of lncRNAs and mRNAs,and we identified putative transcription factors orchestrating cell-type-specific expression of *** analysis results are available at the single-cell-based plant lncRNA atlas data-base(scPLAD;https://***/scPLAD/).Overall,this work demonstrates the power of inte-grative single-cell data analysis applied to plant lncRNA biology and provides fundamental insights into lncRNA expression specificity and associated gene regulation.

关键词： single-cell transcriptomics long noncoding RNAs lncRNAs gene regulatory networks GRNs plants

Distribution and linkage disequilibrium analysis of polymorphisms of GHl gene in different populations of pigs,associated with body size

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Distribution and linkage disequilibrium analysis of polymorp...

Naphthalene diimide-based cathode interlayer material enables 20.2% efficiency in organic photovoltaic cells

第七届中国畜牧科技论坛

作者： Cheng yunyun Liu songcai Su dan Lu chao Zhang xin Wu qingyan Li siming fu haoyu Yu hao Hao linlin College of Animal Science Jilin University Five-Star Animal Health Pharmaceutical Factory

Growth hormone(GH) has been considered as a candidate gene for growth and body size in *** this study,polymorphisms of the GHl gene were evaluated for associations with body size traits in 190 pig *** single nucleotide polymorphisms(SNPs) were identified in GHl gene of the large pig breeds and miniature pig breeds using directly sequencing and genotyped by AS-PCR ***,six(g.237A>G,g.283T>C.g.309A>G,g.318A>G,g.540A>G and g.544A>G) of them were significantly associated with body size,of which three loci(g.283T>C,g.309A>G,g.318A>G) located in the signal peptide coding region of GHl gene compose a CGG haplotype for large pigs and TAA haplotype for miniature pigs(PG and g.544A>G) located in the second intron of GHl gene compose a GG haplotype for large pigs and AA haplotype for miniature pigs(P<0.001).In conclusion,our results demonstrate that these SNPs in GH1 gene are associated with the body size of pigs,providing genetic basis for pig breeding with the improved economic benefits.

关键词： growth hormone single nucleotide polymorphisms(SNPs) linkage disequilibrium analysis body size

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Science China Chemistry 2024年

作者： Yue Yu Jianqiu Wang Zhihao Chen Yang Xiao Zhen fu Tao Zhang haoyu Yuan Xiao-Tao Hao Long Ye Yong Cui Jianhui Hou State Key Laboratory of Polymer Physics and Chemistry Beijing National Laboratory for Molecular Sciences Institute of Chemistry Chinese Academy of Sciences University of Chinese Academy of Sciences School of Physics State Key Laboratory of Crystal Materials Shandong University Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Materials Science and Engineering Beijing University of Chemical Technology School of Materials Science and Engineering Tianjin University

Cathode interlayer(CIL) materials play an important role in improving the power conversion efficiency(PCE) of organic photovoltaic(OPV) cells. However, the current understanding of the structure-property relationship in CIL materials is limited, and systematic studies in this regard are scarce. Here, two new CIL materials, NDI-PhC 4 and NDI-PhC 6 were synthesized by varying the alkylamine chain length on the NDI-Ph core. Our investigation reveals a systematic variation in the physical and chemical properties of these materials with increasing alkylamine chain length. Specifically, we observe a sequential decrease in melting point and self-doping effect, accompanied by an enhancement in crystallinity. Among these CIL materials, NDI-PhC 4 has a notable balance across various performance metrics. It also exhibits excellent surface modification capabilities, leading to a low surface roughness. Consequently, OPV cells based on NDI-PhC 4 achieve a PCE of 20.2%, which is one of the highest reported efficiencies for OPV cells. In addition, the appropriate melting point of NDI-PhC 4 contributes to the excellent stability of OPV cells.

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