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Digital Communications and Networks 2024年第1期10卷 25-37页

作者： Daosen Zhai Huan Li Xiao Tang Ruonan Zhang haotong Cao School of Electronics and Information Northwestern Polytechnical UniversityXian710072China State Key Laboratory of Integrated Services Networks Xidian UniversityXian710071China Department of Computing Hong Kong Polytechnic UniversityHong Kong SARChina

Unbalanced traffic distribution in cellular networks results in congestion and degrades spectrum *** tackle this problem,we propose an Unmanned Aerial Vehicle(UAV)-assisted wireless network in which the UAV acts as an aerial relay to divert some traffic from the overloaded cell to its adjacent underloaded *** fully exploit its potential,we jointly optimize the UAV position,user association,spectrum allocation,and power allocation to maximize the sum-log-rate of all users in two adjacent *** tackle the complicated joint optimization problem,we first design a genetic-based algorithm to optimize the UAV ***,we simplify the problem by theoretical analysis and devise a low-complexity algorithm according to the branch-and-bound method,so as to obtain the optimal user association and spectrum allocation *** further propose an iterative power allocation algorithm based on the sequential convex approximation *** simulation results indicate that the proposed UAV-assisted wireless network is superior to the terrestrial network in both utility and throughput,and the proposed algorithms can substantially improve the network performance in comparison with the other schemes.

关键词： Load balance Unmanned aerial vehicle Userassociation Resource management

SeeMore: a spatiotemporal predictive model with bidirectional distillation and level-specific meta-adaptation

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Science China(Information Sciences) 2024年第8期67卷 147-171页

作者： Yuqing MA Wei LIU Yajun GAO Yang YUAN Shihao BAI haotong QIN Xianglong LIU State Key Lab of Software Development Environment Beihang University

Predicting future frames using historical spatiotemporal data sequences is challenging and critical, and it is receiving a lot of attention these days from academic and industrial scholars. Most spatiotemporal predictive algorithms ignore the valuable backward reasoning ability and the disparate learning complexities among different layers and hence, cannot build good long-term dependencies and spatial correlations,resulting in suboptimal solutions. To address the aforementioned issues, we propose a two-stage coarse-to-fine spatiotemporal predictive model with bidirectional distillation and level-specific meta-adaptation(See More)in this paper, which includes a bidirectional distillation network(BDN) and a level-specific meta-adapter(LMA), to gain bidirectional multilevel reasoning. In the first stage, BDN concentrates on bidirectional dynamics modeling and coarsely constructs spatial correlations of different layers, while LMA is introduced in the second fine-tuning stage to refine the multilevel spatial correlations from a meta-learning *** particular, BDN mimics the forward and backward reasoning abilities of humans in a distillation manner,which aids in the development of long-term dependencies. The LMA views learning of different layers as disparate but related tasks and guides the transfer of learning experiences among these tasks through learning complexities. Thus, each layer could be closer to its solutions and could extract more informative spatial correlations. By capturing the enhanced short-term spatial correlations and long-term temporal dependencies,the proposed model could extract adequate knowledge from sequential historical observations and accurately predict future frames whose backtracking preconditions are consistent with the historical sequence. Our work is general and robust enough to be integrated into most spatiotemporal predictive models without requiring additional computation or memory cost during inference. Extensive experimen

关键词： spatiotemporal predictive learning knowledge transfer bidirectional distillation network level-specific meta-adapter coarse-to-fine training

MAD2.2.overexpression attenuates the effects of TNF-α-induced migration and invasion capabilities in colorectal cancer cells

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BIOCELL 2024年第9期48卷 1311-1322页

作者： haotong SUN HEYING WANG YANJIE HAO XIN LI JUN LING HUAN WANG FEIMIAO WANG FANG XU School of Basic Medicine Medical Genetics and Cell BiologyNingxia Medical UniversityYinchuan750004China Key Laboratory of Reproduction and Genetics Ningxia Medical UniversityYinchuan750004China

Background:Colorectal cancer is a major global health concern,exacerbated by tumor necrosis factor-alpha(TNF-α)and its role in inflammation,with the effects of Mitotic Arrest Deficient 2.Like 2.MAD2.2.in this context still ***:The colorectal carcinoma cell lines HCT116 and SW62. were exposed to TNF-αfor a period of 2. h to instigate an inflammatory *** assessments were conducted to measure the expression of inflammatory cytokines,the activity within the p38 mitogen-activated protein kinase(p38 MAPK)and Phosphoinositide 3-Kinase/AKT Serine/Threonine Kinase pathway(PI3K/AKT)signaling *** sequencing and subsequent integrative analysis with the Cancer Genome Atlas(TCGA)program database revealed a significant downregulation of the key factor *** of MAD2.2.expression was facilitated via lentiviral vector-mediated *** influence of this overexpression on TNF-α-prompted inflammation,intracellular signaling pathways,and the migratory and invasive behaviors of the colorectal cancer cells was then ***:TNF-αtreatment significantly increased the expression of Interleukin-1 beta(IL-1β)and Interleukin-6(IL-6),activated the MAPK p38 and PI3K/AKT signaling pathways,and enhanced cell migration and invasion.A decrease in MAD2.2.expression was observed following TNF-α***,overexpression of MAD2.2.reversed the effects of TNF-α,reducing IL-1βand IL-6 levels,attenuating PI3K/AKT pathway activation,and inhibiting cell migration and ***:Overexpression of MAD2.2.attenuates the pro-inflammatory effects of TNF-α,suggesting that MAD2.2.plays a protective role against TNF-α-induced migration and invasion of colorectal carcinoma ***,MAD2.2.holds potential as a therapeutic target in the treatment of colorectal cancer.

关键词： Colorectal cancer TNF-α MAD2.2 Migration Invasion

Probing the Galactic Halo with RR Lyrae *** Radial Velocity Curve Templates of RRc Stars

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Research in Astronomy and Astrophysics 2024年第7期24卷 118-134页

作者： Yue Huang Min Fang Gaochao Liu Xianzhong Zheng Sarah Ann Bird Yang Huang Jianrong Shi Jiangtao Wang Huawei Zhang Haijun Tian haotong Zhang College of Science China Three Gorges UniversityYichang 443002China Center for Astronomy and Space Sciences China Three Gorges UniversityYichang 443002China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China School of Astronomy and Space Science University of Science and Technology of ChinaHefei 230026China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesBeijing 100101China Department of Astronomy School of PhysicsPeking UniversityBeijing 100871China Kavli Institute for Astronomy and Astrophysics Peking UniversityBeijing 100871China School of Sciences Hangzhou Dianzi UniversityHangzhou 310018China

We present radial velocity(RV)curve templates of RR Lyrae first-overtone(RRc)stars constructed with the Mg I b triplet and Hαlines using time-domain Medium-Resolution Survey spectra of seven RRc stars from Large Sky Area Multi-Object Fiber Spectroscopic Telescope(LAMOST)Data Release ***,we derive the relation between the stellar RV curve amplitudes and g-band light curve amplitudes from Zwicky Transient Facility(ZTF)public *** those RRc stars without ZTF g-band light curves,we provide the conversions from the light curve amplitudes in ZTF r-and i-bands,Gaia G-band,and V-band from the All-Sky Automated Survey for Supernovae to those in ZTF *** validate our RV curve templates using the RRc star SV Scl and find the uncertainties of systemic RV are less than 2.11 km s~(-1)and 6.08 km s~(-1)based on the Mg I b triplet and Hαlines,*** calculate the systemic RVs of 30 RRc stars using the RV curve templates constructed with the Mg I b triplet and Hαlines and find the systemic RVs are comparable with each *** RV curve template will be particularly useful for obtaining the systemic RV of RRc using the LAMOST spectroscopy.

关键词： stars variables RR Lyrae-Stars-techniques radial velocities

东西文化谱系中“生命”与“美”的通变——中日“身体美学”的观念及其表现的比较

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中国比较文学 2024年第3期 254-271页

作者：杨皓童吉林大学文学院

对于身体美学问题的理解和判断,往往最能体现人类文化之间的普遍价值异同。在中日文化比较研究中,通过渊源、表现、意义、艺术直观和文本理解等环节,聚焦于身体美学问题的探讨,可以把握同为东方文化谱系中“生命”与“美”的观念的相通... 详细信息

对于身体美学问题的理解和判断,往往最能体现人类文化之间的普遍价值异同。在中日文化比较研究中,通过渊源、表现、意义、艺术直观和文本理解等环节,聚焦于身体美学问题的探讨,可以把握同为东方文化谱系中“生命”与“美”的观念的相通性和差异性。在西方美学体系的强势话语影响下,如何从中日身体美学的探源、比较和分析评价中获得“自己说”的理论资源和实践经验,是建构“一起说”的当代身体美学话语的有效途径。

关键词：东方文化生命与美中日传统文化身体美学

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鲁迅日文书写的基本形态与“时代节点”

鲁迅研究月刊 2024年第5期 74-80页

作者：杨皓童吉林大学文学院 130012

鲁迅的日文写作和与日本友人的通信是中日文化交流中不可或缺的一部分,对于了解鲁迅文学创作风貌和思想品格起着独特的作用。鲁迅与日本友人的通信活动不仅推动了中日文化的交流,也促进了两国人民之间的相互理解和友谊。这些日文书写作... 详细信息

鲁迅的日文写作和与日本友人的通信是中日文化交流中不可或缺的一部分,对于了解鲁迅文学创作风貌和思想品格起着独特的作用。鲁迅与日本友人的通信活动不仅推动了中日文化的交流,也促进了两国人民之间的相互理解和友谊。这些日文书写作品至今仍具有重要的历史意义,为我们提供了独特的视角。鲁迅的日文书写作品所处的时代背景和时间节点问题,不仅仅是简单的历史时间关联,更深层地反映了时代环境、人际关系和作者思想等方面的原因。在2.世纪二三十年代这一关键时期,鲁迅通过中文文学作品和日文杂文的创作,以及与日本友人的通信,对社会现实和国际局势进行了冷静的审视和反思,展现了作为文学家和知识分子的敏锐洞察力和深刻关怀。

关键词：鲁迅日文书写时代节点

PBX/Knotted 1 homeobox-2.PKNOX2.is a novel regulator of myocardial fibrosis

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Signal Transduction and Targeted Therapy 2024年第5期9卷 2231-2249页

作者： Liang Chen haotong Li Xiaorui Liu Ningning Zhang Kui Wang Anteng Shi Hang Gao Deniz Akdis Ardan MSaguner Xinjie Xu Elena Osto Willem Van de Veen Guangyu Li Antoni Bayés-Genís Firat Duru Jiangping Song Xiangjie Li Shengshou Hu State Key Laboratory of Cardiovascular Disease Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingP.R.China School of Statistics and Data Science Nankai UniversityTianjinChina Department of Cardiology University Heart CenterUniversity Hospital Zurich and University of ZurichZurichSwitzerland Institute for Clinical Chemistry University Hospital Zurich and University of ZürichZurichSwitzerland Swiss Institute of Allergy and Asthma Research(SIAF) University of ZurichDavosSwitzerland Heart Institute Hospital Universitari Germans Trias i PujolBadalonaCIBERCVSpain

Much effort has been made to uncover the cellular heterogeneities of human hearts by single-nucleus RNA ***,the cardiac transcriptional regulation networks have not been systematically described because of the limitations in detecting transcription *** this study,we optimized a pipeline for isolating nuclei and conducting single-nucleus RNA sequencing targeted to detect a higher number of cell signal genes and an optimal number of transcription *** this unbiased protocol,we characterized the cellular composition of healthy human hearts and investigated the transcriptional regulation networks involved in determining the cellular identities and functions of the main cardiac cell *** in fibroblasts,a novel regulator,PKNOX2.was identified as being associated with physiological fibroblast activation in healthy *** validate the roles of these transcription factors in maintaining homeostasis,we used single-nucleus RNA-sequencing analysis of transplanted failing hearts focusing on fibroblast *** trajectory analysis suggested that PKNOX2.was abnormally decreased from fibroblast activation to pathological myofibroblast *** gain-and loss-of-function in vitro experiments demonstrated the inhibitory role of PKNOX2.in pathological fibrosis ***,fibroblast-specific overexpression and knockout of PKNOX2.in a heart failure mouse model induced by transverse aortic constriction surgery significantly improved and aggravated myocardial fibrosis,*** summary,this study established a high-quality pipeline for single-nucleus RNA-sequencing analysis of heart *** this optimized protocol,we described the transcriptional regulation networks of the main cardiac cell subtypes and identified PKNOX2.as a novel regulator in suppressing fibrosis and a potential therapeutic target for future translational studies.

关键词： NOX2 homeostasis fibrosis

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IPEF与RCEP:差异、影响及相关思考

亚太经济 2024年第4期 10-17页

作者：卢光盛赵皓童云南大学国际关系研究院·区域国别研究院昆明650091 云南大学周边外交研究中心昆明650091

“印太经济框架”(IPEF)是拜登政府“印太战略”下的经济支柱。在《区域全面经济伙伴关系协定》(RCEP)全面生效的背景下,IPEF的出现将对亚太地区经贸格局产生巨大影响。IPEF与RCEP同为大型区域性经贸协定,二者在成员国、经济体量、运行... 详细信息

“印太经济框架”(IPEF)是拜登政府“印太战略”下的经济支柱。在《区域全面经济伙伴关系协定》(RCEP)全面生效的背景下,IPEF的出现将对亚太地区经贸格局产生巨大影响。IPEF与RCEP同为大型区域性经贸协定,二者在成员国、经济体量、运行机制、规则内容与战略意图上存在差异。美国推行IPEF对RCEP的潜在影响主要围绕在数字经贸规则、地区供应链体系以及亚太地区经济发展格局等方面。对此,RCEP成员国应加快布局,通过强化区域合作关系、进一步深化RCEP合作、完善相关领域规则,在弥合来自IPEF冲击的同时不断挖掘亚太地区经贸发展提升路径,以合作推动区域经济一体化发展更进一步。

关键词： IPEF RCEP 差异影响区域经济一体化

基于文丘里管的湿天然气在线计量技术研究与应用

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石油石化节能与计量 2024年第6期14卷 76-81页

作者：施昊彤国家石油天然气管网集团有限公司建设项目管理分公司

为实现湿天然气的在线不分离计量,取代现有分离器的单独计量方式,在梳理湿天然气计量模型的基础上,通过CFD技术模拟单一气相、单一液相和等量气液两相流经文丘里管压差流量计时的压力分布和速度分布,考察不同气相流量和液相流量下的静... 详细信息

为实现湿天然气的在线不分离计量,取代现有分离器的单独计量方式,在梳理湿天然气计量模型的基础上,通过CFD技术模拟单一气相、单一液相和等量气液两相流经文丘里管压差流量计时的压力分布和速度分布,考察不同气相流量和液相流量下的静压参数,以此计算虚高系数,并通过非线性拟合得到虚高系数与气相流量、液相流量和管道内压的关系,最后通过湿气流量计现场对比测试撬完成效果验证。结果表明:单一液相的轴向压降较小,气液两相在收缩段和喉道处的压降最大,单一气相流量计的计量结果存在虚高现象;气相和液相流量越大,虚高现象越明显,虚高流量值与实际值的差异越大;在线湿气流量计的气相计量误差范围为-0.8%~6.3%,液相计量误差范围为-2..1%~-0.3%,准确度基本满足现场计量需求,具有较高的实用价值。

关键词：湿天然气在线计量虚高系数 CFD 文丘里管气相流量液相流量

基于蝴蝶结-贝叶斯网络的站场储罐动态风险评价

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石油化工自动化 2024年第1期60卷 56-61页

作者：施昊彤国家管网集团建设项目管理分公司西四线新疆工程项目部

为实现站场储罐区风险的实时评估和事故预防，在建立蝴蝶结模型的基础上，通过映射规则引入时间维度，归纳了储罐泄漏的主要危险源和不同安全屏障下的事故后果类型，通过遗漏概率模型确定了不同节点的条件概率，以此形成站场储罐的动态... 详细信息

为实现站场储罐区风险的实时评估和事故预防，在建立蝴蝶结模型的基础上，通过映射规则引入时间维度，归纳了储罐泄漏的主要危险源和不同安全屏障下的事故后果类型，通过遗漏概率模型确定了不同节点的条件概率，以此形成站场储罐的动态贝叶斯网络模型，推理出储罐事故发生概率随时间的变化规律，并进行实例分析和验证。结果表明：储罐泄漏概率先增大后减小，并在第3个时间片处达到峰值；后验概率较大的基本事件均与储罐腐蚀的中间事件相关，随着时间片的延长，严重腐蚀等级呈线性上升，中等腐蚀等级基本保持不变，轻微腐蚀等级呈指数下降；在第10个时间片上，油气聚集的事故后果发生概率最大，蒸气云爆炸的事故后果发生概率最小，说明强化紧急停车系统和避免形成受限空间是减轻事故后果的有效途径。

关键词：蝴蝶结模型贝叶斯网络储罐区风险时间片