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Science China Chemistry 2024年第5期67卷 1373-1374页

作者： haoran Wang Ben zhong Tang Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction Department of Chemistry.Institute of Molecular Functional MaterialsState Key Laboratory of NeuroscienceDivision of Biomedical Engineering and Division of Life ScienceThe Hong Kong University of Science and TechnologyHong Kong 999077China School of Science and Engineering Shenzhen Institute of Aggregate Science and Technology The Chinese University of Hong KongShenzhen(CUHK-Shenzhen)Shenzhen 518172China

Nanotechnology hailed as a revolutionary new technology of the 21st century, has ignited a wave of innovation across diverse fields spanning chemistry, physics, materials science,medicine, engineering, and electronics. In 2016, Nature published an article titled “The nanolight revolution is coming”, underscoring that “virus-sized particles that emit light in every color could transform applications ranging from television displays to cancer treatment”.

关键词： sized loading treatment

AlphaMobileSensing:A virtual testbed for mobile environmental monitoring

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Building Simulation 2023年第7期16卷 1027-1040页

作者： Qi Zhou haoran zhong Linyan Li Zhe Wang Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHong KongChina School of Data Science City University of Hong KongHong KongChina HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute FutianShenzhenChina

Environmental monitoring plays a critical role in creating and maintaining a comfortable,productive,and healthy environment.Built upon the advancements of robotics and data processing,mobile sensing demonstrates its potential to address problems regarding cost,deployment,and resolution that stationary monitoring encounters,which therefore has attracted increasing research attentions recently.To facilitate mobile sensing,two key algorithms are needed:the field reconstruction algorithm and the route planning algorithm.The field reconstruction algorithm is to reconstruct the entire environment field from spatially-and temporally-discrete measurements collected by the mobile sensors.The route planning algorithm is to instruct the mobile sensors where the mobile sensor needs to move to for the next measurements.The performance of mobile sensors highly depends on these two algorithms.However,developing and testing those algorithms in the real world is expensive,challenging,and time-consuming.To address these issues,we proposed and implemented an open-source virtual testbed,AlphaMobileSensing,that can be used to develop,test,and benchmark mobile sensing algorithms.AlphaMobileSensing aims to help users more easily develop and test the field reconstruction and route planning algorithms for mobile sensing solutions,without worrying about hardware fault,test accidents(such as collision during the test),etc.The separation of concerns can significantly reduce the cost of developing software solutions for mobile sensing.For versatility and flexibility,AlphaMobileSensing was wrapped up using the standardized interface of OpenAI Gym,and it also provides an interface for loading physical fields that were generated by numerical simulations as virtual test sites to perform mobile sensing and retrieving monitoring data.We demonstrated applications of the virtual testbed by implementing and testing algorithms for physical field reconstruction in both static and dynamic indoor thermal environments.AlphaMobileSensing provides a novel a

关键词： mobile sensing environmental monitoring indoor environmental quality environmental field reconstruction

Tourmaline guiding the electric field and dechlorination pathway of 2,3-dichlorophenol by Desulfitobacterium hafniense

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Journal of Environmental Sciences 2024年第1期135卷 262-273页

作者： Yue Lu Fangyi Liang Fanzhi Qin Linrui zhong Jianhong Jiang Qi Liu Shoujuan Zhang Ming Yan Changzheng Fan haoran Dong College of Environmental Science and Engineering Hunan UniversityChangsha 410082China Shenzhen Research Institute Hunan UniverisyShenzhen 510082China Key Laboratory of Environment Biology and Pollution Control Hunan UniversityMinistry of EducationChangsha 410082China China Machinery International Engineering Design&Research Institute Co. Ltd.Changsha 410007China Hunan Engineering Research Center for Water Treatment Process&Equipment Changsha 410007China

The dehalogenation of organohalides has been a research hotspot in bioremediation field;however,the influence of tourmaline,a natural ore that can generate spontaneous electric field,on organohalide-respiring bacteria(OHRB)and their dechlorination process is not well known.In this study,the effect and mechanism of tourmaline on the reductive dechlorination of 2,3-dichlorophenol(2,3-DCP)by Desulfitobacterium hafniense DCB-2Twere explored.The characterization results confirmed that tourmaline had good stability and the optimal dosage of tourmaline was 2.5 g/L,which shortened the total time required for dechlorination reaction to 72 hr.Besides,tourmaline amendment also increased the proportion of 2-chlorophenol(2-CP)from 18%to 30%of end products,while that of 3-CP decreased correspondingly.The theoretical calculations showed that the bond charge of the orthosubstituted chlorine declined from-0.179 to-0.067,and that of meta-substituted chlorine increased from-0.111 to-0.129,which indicated that the spontaneous electric field of tourmaline affected the charge distribution of 2,3-DCP and was more conducive to the generation of 2-CP.Overall,tourmaline with the spontaneous electric field affected the reductive dechlorination pathway of Desulfitobacterium,and the tourmaline-OHRB combining system might serve as a novel strategy for the bioremediation of environments polluted with chlorinated phenols.

关键词： Reductive dechlorination Desulfitobacterium hafniense Tourmaline Electric field 2 3-dichlorophenol

Long distance all-optical logic operations through a single multimode fiber empowered by wavefront shaping

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Photonics Research 2024年第3期12卷 587-597页

作者： ZHIPENG YU TIANTING zhong HUANHAO LI haoran LI CHI MAN WOO SHENGFU CHENG SHUMING JIAO HONGLIN LIU CHAO LU PUXIANG LAI Department of Biomedical Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518000China Peng Cheng Laboratory Shenzhen 518055China Key Laboratory for Quantum Optics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Department of Electronic and Information Engineering The Hong Kong Polytechnic UniversityHong Kong SARChina Photonics Research Institute The Hong Kong Polytechnic UniversityHong Kong SARChina

Multimode fibers(MMFs)are a promising solution for high-throughput signal transmission in the time domain.However,crosstalk among different optical modes within the MMF scrambles input information and creates seemingly random speckle patterns at the output.To characterize this process,a transmission matrix(TM)can be used to relate input and output fields.Recent innovations use TMs to manipulate the output field by shaping the input wavefront for exciting advances in deep-brain imaging,neuron stimulation,quantum networks,and analog operators.However,these approaches consider input/output segments as independent,limiting their use for separate signal processing,such as logic operations.Our proposed method,which makes input/output segments as interdependent,adjusts the phase of corresponding output fields using phase bias maps superimposed on input segments.Coherent superposition enables signal logic operations through a 15-m-long MMF.In experiments,a single optical logic gate containing three basic logic functions and cascading multiple logic gates to handle binary operands is demonstrated.Bitwise operations are performed for multi-bit logic operations,and multiple optical logic gates are reconstructed simultaneously in a single logic gate with polarization multiplexing.The proposed method may open new avenues for long-range logic signal processing and transmission via MMFs.

关键词： optical polarization fiber

Porous 2D CuO nanosheets for efficient triethylamine detection at low temperature

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Chinese Chemical Letters 2023年第2期34卷 588-592页

作者： Feng Wang haoran zhong Zhenlu Chen Ding Wang Zhuangchai Lai Yonghui Deng Xianying Wang School of Materials and Chemistry University of Shanghai for Science&TechnologyShanghai 200093China Department of Applied Physics The Hong Kong Polytechnic UniversityHong KongChina Department of Chemistry Fudan UniversityShanghai 200433China Shanghai Institute of Ceramics Chinese Academy of SciencesShanghai 200050China

The freshness of seafood can be judged by detecting the concentration of triethylamine(TEA). In this work, 2D Cu O porous nanosheets(Cu O PNs) were prepared by a graphene oxide template method and their particle sizes were regulated by changing the calcination temperature. Their structure, morphology and gas sensing performances were investigated by various characterization methods. The response(Rg/Ra) of the gas sensor based on Cu O PNs calcined at 700oC was as high as 440-100 ppm TEA at the operating temperature of 40 ℃. The detection limit was as low as 0.25 ppm. In addition, the gas sensor has good selectivity and stability. The excellent TEA sensitivity is mainly resulted from the appropriate particle size and loose porous framework. This work not only paves the way to explore the novel low temperature TEA gas sensors, but also provides deep insight on improving the structure and properties of gas sensitive materials by controlling the calcination temperature.

关键词： CuO nanosheets Gas sensor Porous materials Triethylamine detection Low operating temperature

Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people

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Journal of Genetics and Genomics 2024年第5期51卷 517-530页

作者： Yuntao Sun Mengge Wang Qiuxia Sun Yan Liu Shuhan Duan Zhiyong Wang Yunyu Zhou Jun zhong Yuguo Huang Xinyu Huang Qingxin Yang Xiangping Li haoran Su Yan Cai Xiucheng Jiang Jing Chen Jiangwei Yan Shengjie Nie Liping Hu Junbao Yang Renkuan Tang Chuan-Chao Wang Chao Liu Xiaohui Deng Libing Yun Guanglin He West China School of Basic Science&Forensic Medicine Sichuan UniversityChengduSichuan 610041China Institute of Rare Diseases West China Hospital of Sichuan UniversitySichuan UniversityChengduSichuan 610000China Center for Archaeological Science Sichuan UniversityChengduSichuan 610000China Faculty of Forensic Medicine Zhongshan School of MedicineSun Yat-sen UniversityGuangzhouGuangdong 510275China Guangzhou Forensic Science Institute GuangzhouGuangdong 510055China Department of Forensic Medicine College of Basic MedicineChongqing Medical UniversityChongqing 400331China School of Clinical Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Basic Medical Sciences North Sichuan Medical CollegeNanchongSichuan 637100China School of Forensic Medicine Kunming Medical UniversityKunmingYunnan 650500China School of Stomatology North Sichuan Medical CollegeNanchongSichuan 637100China Department of Medical Laboratory North Sichuan Medical CollegeNanchongSichuan 637007China School of Life Sciences Xiamen UniversityXiamenFujian 361005China Anti-Drug Technology Center of Guangdong Province GuangzhouGuangdong 510230China School of Forensic Medicine Shanxi Medical UniversityJinzhongShanxi030600China

Tibeto-Burman(TB)people have endeavored to adapt to the hypoxic,cold,and high-UV high-altitude environments in the Tibetan Plateau and complex disease exposures in lowland rainforests since the late Paleolithic period.However,the full landscape of genetic history and biological adaptation of geographically diverse TB-speaking people,as well as their interaction mechanism,remain unknown.Here,we generate a whole-genome meta-database of 500 individuals from 39 TB-speaking populations and present a comprehensive landscape of genetic diversity,admixture history,and differentiated adaptative features of geographically different TB-speaking people.We identify genetic differentiation related to geography and language among TB-speaking people,consistent with their differentiated admixture process with incoming or indigenous ancestral source populations.A robust genetic connection between the Tibetan-Yi corridor and the ancient Yellow River people supports their Northern China origin hypothesis.We finally report substructure-related differentiated biological adaptative signatures between highland Tibetans and Loloish speakers.Adaptative signatures associated with the physical pigmentation(EDAR and SLC24A5)and metabolism(ALDH9A1)are identified in Loloish people,which differed from the high-altitude adaptative genetic architecture in Tibetan.TB-related genomic resources provide new insights into the genetic basis of biological adaptation and better reference for the anthropologically informed sampling design in biomedical and genomic cohort research.

关键词： Tibeto-Burman people Geneticprofile Natural selection Geneticdiversity Biological adaptation

跨膜蛋白201在肝细胞癌中的表达及其预后意义与作用机制

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中国普通外科杂志 2024年第1期33卷 61-73页

作者：孙丹费浩然仲成成杨海深司鑫鑫胡伟王仲锦州医科大学辽宁锦州121001 江苏省连云港市第一人民医院肝胆外科江苏连云港222001 江苏海洋大学药学院江苏连云港222005

背景与目的:研究发现跨膜蛋白(TMEM)家族基因与肿瘤关系密切,TMEM201是TMEM家族的一员,其在肝细胞癌(HCC)中的表达与作用目前尚不清楚。因此,本研究通过生物信息学方法分析TMEM201在HCC中的表达与作用,并预测其在HCC中可能作用的通路,... 详细信息

背景与目的:研究发现跨膜蛋白(TMEM)家族基因与肿瘤关系密切,TMEM201是TMEM家族的一员,其在肝细胞癌(HCC)中的表达与作用目前尚不清楚。因此,本研究通过生物信息学方法分析TMEM201在HCC中的表达与作用,并预测其在HCC中可能作用的通路,进而探讨机制。方法:在TIMER中分析TMEM201在泛癌中的表达。下载TCGA与GEO数据库中HCC患者数据,并收集106例HCC患者的手术标本与临床信息,分析TMEM201在肝癌组织与癌旁组织中的表达情况,并绘制生存曲线,分析TMEM201表达与HCC患者的预后关系。用单因素与多因素Cox分析判断HCC相关危险因素。根据TCGA与临床数据,分析TMEM201的表达与HCC患者临床病理特征的关系。应用String和GeneMANIA数据库绘制与TMEM201及其相关基因的网络图谱。通过TCGA数据库分析TMEM201与免疫细胞的关系。通过LinkedOmics数据库分析与TMEM201相关的共表达基因,并对共表达基因进行GO功能分析与KEGG通路预测。结果:泛癌分析结果显示,TMEM201在绝大部分肿瘤中呈高表达。多数据库及临床HCC标本免疫组化分析显示,TMEM201在HCC组织中的表达明显高于癌旁组织(均P<0.05),且TMEM201高表达患者生存时间明显短于低表达患者。单因素与多因素Cox风险回归提示TMEM201的表达是HCC患者总体生存率的独立危险因素。蛋白质互作网络、GeneMANIA数据库分析显示,TMEM201与SUN1、SUN2、LMNB1、EMD等基因存在明显相互作用。免疫浸润分析结果显示,TMEM201表达与树突状细胞、细胞毒性细胞、Th2细胞等明显有关。此外,功能富集分析显示,TMEM201与共表达基因参与了许多HCC的生物学过程、细胞组成、分子功能和作用通路。通路结果及相关性热图提示TMEM201与细胞周期高度相关。结论:TMEM201在HCC组织中高表达,是影响HCC患者预后的独立危险因素,TMEM201在HCC中的作用机制可能与免疫浸润的调节、细胞周期的调控有关。

关键词：癌,肝细胞跨膜蛋白201 预后计算生物学

中国香港中学文凭考试地理学科“实地考察为本题目”的设立、评析与启示

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地理教学 2024年第8期 23-27页

作者：陈浩然钟嘉灏广州大学地理科学与遥感学院广东广州510006 澳门大学社会科学学院中国澳门999078

地理实践力是地理学科核心素养之一,学界在其教学上已积累较多成果,却仍待改善其在高考评价体系的呈现形式。中国香港中学文凭考试地理学科的“实地考察为本题目”是对学生地理探究能力的正式评价,具有“坚持科学研究取向”“聚焦地理... 详细信息

地理实践力是地理学科核心素养之一,学界在其教学上已积累较多成果,却仍待改善其在高考评价体系的呈现形式。中国香港中学文凭考试地理学科的“实地考察为本题目”是对学生地理探究能力的正式评价,具有“坚持科学研究取向”“聚焦地理实践数据”“关注地理系统综合”“固定设置开放试题”的特征,对内地地区推进完善教学评价体系、创设考查地理实践题型、量化区域地理环境特色有启示作用。

关键词：实地考察为本题目中国香港中学文凭考试地理实践力地理探究能力高考评价体系

两级变幅应变疲劳本征损伤耗散寿命预测模型研究

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力学学报 2024年第1期56卷 149-156页

作者：李文奇向忠李浩然任忠凯王嘉栋浙江理工大学机械工程学院杭州310018 太原理工大学机械与运载工程学院太原030024

在变幅低周疲劳载荷条件下,材料的疲劳损伤累积过程中呈现出了显著的载荷顺序效应.这种现象复杂化了变幅疲劳寿命的预测,因此,如何更精确地预测变幅低周载荷下的疲劳寿命,已经成为了一个亟待解决的问题.针对变幅低周疲劳载荷下损伤累积... 详细信息

在变幅低周疲劳载荷条件下,材料的疲劳损伤累积过程中呈现出了显著的载荷顺序效应.这种现象复杂化了变幅疲劳寿命的预测,因此,如何更精确地预测变幅低周载荷下的疲劳寿命,已经成为了一个亟待解决的问题.针对变幅低周疲劳载荷下损伤累积表现的载荷顺序效应,考虑到本征损伤耗散与疲劳损伤构成一一映射,且刻画低周疲劳破坏的热力学本质,基于连续介质损伤力学及其不可逆热力学框架,推导本征损伤耗散功演化模型D型描述并以等同本征损伤耗散功作为损伤转换条件,建立了一种考虑载荷顺序效应的变幅低周疲劳寿命预测模型.为了验证新模型的有效性和先进性,进行了P355NL1结构钢和Ti-6Al-4V钛合金在两级变幅载荷下的单轴低周疲劳实验验证,并与Manson模型、Kwofie模型和Peng模型进行了比较分析.研究结果表明,新建模型的预测效果都在1.5倍的误差范围内,与实验结果相当吻合,且优于现有的预测模型.运用本征损伤耗散理论开展变幅疲劳寿命预测,为金属材料变幅疲劳寿命预测提供了新思路.

关键词：低周疲劳载荷顺序效应损伤力学本征损伤耗散寿命预测

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改性海泡石对污泥热解过程中重金属的控制

化工进展 2024年第1期43卷 541-550页

作者：任鹏锟仲兆平杨宇轩张杉杜浩然李骞东南大学能源与环境学院江苏南京210096

污泥热解过程中会不可避免地产生多种重金属,危害人类的健康。通过在水平固定床反应器内开展城市污泥与改性海泡石共热解实验,探究海泡石的盐酸浸渍浓度(2~6mol/L)、海泡石的热活化温度(750~950℃)以及污泥与海泡石共热解温度(400~600℃... 详细信息

污泥热解过程中会不可避免地产生多种重金属,危害人类的健康。通过在水平固定床反应器内开展城市污泥与改性海泡石共热解实验,探究海泡石的盐酸浸渍浓度(2~6mol/L)、海泡石的热活化温度(750~950℃)以及污泥与海泡石共热解温度(400~600℃)对污泥热解炭中重金属元素Cd、Zn、Pb、Cr的富集特征、形态变化及生态风险的影响。研究发现,在400~600℃的温度范围内改性海泡石的添加有效地提高了Cd、Zn、Pb的固留率,但对Cr几乎没有富集作用,其中950℃热活化海泡石(950-SEP)对Cd有良好的富集效果,而4mol/L盐酸浸渍海泡石(4H-SEP)对Zn和Pb展现出了更好的富集性能。此外,通过分析重金属赋存形态发现,提高共热解温度和添加改性海泡石,共热解炭中的重金属元素整体向更稳定的形态转化。根据热解炭中重金属的生态风险评估,原始污泥经热解后其生态风险大大降低,在600℃前,改性海泡石可进一步降低重金属的生态风险。

关键词：污泥海泡石重金属热解活化废物处理