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A Note on B-Subdifferential of Projection Operator on Polyhedral Set

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Journal of the Operations Research Society of China 2024年第3期12卷 837-845页

作者： hao-yang liu Jia Wu Li-Wei Zhang Institute of Operations Research and Control Theory School of Mathematical SciencesDalian University of TechnologyDalian116024LiaoningChina

This note characterizes the set of Fréchet-differentiable points of the projection operator on a polyhedral set and the B-subdifferential of this projection operator at any point.

关键词： Polyhedral set Projection operator B-subdifferential Strong regularity

Flow injection chemiluminescence determination of loxoprofen and naproxen with the acidic permanganate-sulfite system

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Journal of Pharmaceutical Analysis 2011年第1期1卷 51-56页

作者： Li-Juan Wang Yu-Hai Tang yang-hao liu Medical School Xi'an Jiaotong UniversityXi'an 710061China Institute of Analytical Sciences Xi'an Jiaotong University Xi'an 710061China

A novel flow injection chemiluminescence（CL）method for the determination of loxoprofen and naproxen was proposed based on the CL system of KMnO4 and Na2SO3 in acid *** CL intensity of KMnO4-Na2SO3 was greatly enhanced in the presence of loxoprofen and *** mechanism of the CL reaction was studied by the kinetic process and UV-vis absorption and the conditions were *** optimized conditions,the CL intensity was linear with loxoprofen and naproxen concentration in the range of 7.0×10^-8-1.0×10^-5g/mL and 2.0×10^-7-4.0×10^-6g/mL with the detection limit of 2.0×10-8g/mL and 3.0×10-8g/mL（S/N=3）,*** relative standard deviations were 2.39% and 1.37% for 5.0×10^-7g/mL naproxen and 5.0×10^-7g/mL loxoprofen（n=10）,*** proposed method was satisfactorily applied to the determination of loxoprofen and naproxen in pharmaceutical preparations.

关键词： chemiluminescence KMnO4 loxoprofen naproxen

Oxidized LDL upregulated ATP binding cassette transporter-1 in THP-1 macrophages

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Acta Pharmacologica Sinica 2004年第5期 39-44页

作者： Chao-ke TANG, Guang-hui YI, Jun-hao yang, Lu-shan liu,Zuo WANG, Chang-geng RUAN, Yong-zong yang2Institute of Cardiovascular Disease of Nanhua University, Hengyang 421001, China

AIM: To study the effect of oxidized low density lipoprotein (ox-LDL) on ATP binding cassette transporter A1(ABCA1) in THP-1 macrophages. METHODS: After exposing the cultured THP-1 macrophages to ox-LDL fordifferent periods, cholesterol efflux was determined by FJ-2107P type liquid scintillator. ABCA1 mRNA and proteinlevel were determined by reverse trancriptase-polymerase chain reaction (RT-PCR) and Western blot, *** cholesterol level in THP-1 macrophage foam cells was detected by high performance liquid ***: ox-LDL elevated ABCA1 in both protein and mRNA levels and increased apolipoprotein (apo) A-I-medi-ated cholesterol efflux in a time- and dose-dependent manner. 22(R)-hydroxycholesterol and 9-cis-retinoic acid didsignificantly increase cholesterol efflux in THP-1 macrophage foam cells (P<0.05), respectively. Both of themfurther promoted cholesterol efflux (P<0.01). As expected, liver X receptor (LXR) agonist decreased content ofesterified cholesterol in the macrophage foam cells compared with control, whereas only a slight decrease of freecholesterol was observed. LXR activity was slightly increased by oxidized LDL by 12 % at 12 h compared with 6 ***, LXR activity was increased about 1.8 times at 24 h, and oxidized LDL further increased LXR activity byabout 2.6 times at 48 h. CONCLUSION: ABCA1 gene expression was markedly increased in cholesterol-loadedcells as a result of activation of LXR/RXR. ABCA1 plays an important role in the homeostasis of cholesterol in themacrophages.

关键词： ATP-binding cassette transporters apolipoprotein A-I hydroxycholesterols LDL lipoproteins oxi-dation-reduction macrophages

Role of the Greenland Sea ice anomaly in the late-spring drought over Northwest China

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 1-5页

作者： yang liu Huopo Chen Nansen-Zhu International Research Centre Institute of Atmospheric Physics Chinese Academy of SciencesBeijingChina Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University for Information Science and TechnologyNanjingChina

Drought across Northwest China in late spring has exerted a vital effect on the local climate and agricultural production,and has been alleviated during the past *** study explored the influence of the preceding Arctic sea ice on the May drought in Northwest China caused by the precipitation *** analysis indicated that when the Greenland Sea ice concentration is abnormally high during February to April,the dry conditions in Northwest China tend to be *** increase of sea ice in the Greenland Sea can excite a meridional circulation,which causes sea surface temperature(SST)anomalies in the North Atlantic via the sea-air interaction,manifested as significant warm SST anomalies over the south of Greenland and the subtropical North Atlantic,but negative SST anomalies over the west of the *** abnormal SST pattern maintains to May and triggers a zonal wave train from the North Atlantic through Scandinavia and Central Asia to Northwest China,leading to abnormal cyclones in Northwest ***,Northwest China experiences a more humid climate than usual.

关键词： Arctic sea ice Greenland Sea North Atlantic SST Drought Northwest China

The role of axon guidance molecules in the pathogenesis of epilepsy

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Neural Regeneration Research 2025年第5期20卷 1244-1257页

作者： Zheng liu Chunhua Pan hao Huang Department of Neurology Affiliated Hospital of Zunyi Medical UniversityZunyiGuizhou ProvinceChina

Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms and mechanisms of action. Increasing evidence suggests that axon guidance molecules play a role in the structural and functional modifications of neural networks and that the dysregulation of these molecules is associated with epilepsy susceptibility. In this review, we discuss the essential role of axon guidance molecules in neuronal activity in patients with epilepsy as well as the impact of these molecules on synaptic plasticity and brain tissue remodeling. Furthermore, we examine the relationship between axon guidance molecules and neuroinflammation, as well as the structural changes in specific brain regions that contribute to the development of epilepsy. Ample evidence indicates that axon guidance molecules, including semaphorins and ephrins, play a fundamental role in guiding axon growth and the establishment of synaptic connections. Deviations in their expression or function can disrupt neuronal connections, ultimately leading to epileptic seizures. The remodeling of neural networks is a significant characteristic of epilepsy, with axon guidance molecules playing a role in the dynamic reorganization of neural circuits. This, in turn, affects synapse formation and elimination. Dysregulation of these molecules can upset the delicate balance between excitation and inhibition within a neural network, thereby increasing the risk of overexcitation and the development of epilepsy. Inflammatory signals can regulate the expression and function of axon guidance molecules, thus influencing axonal growth, axon orientation, and synaptic plasticity. The dysregulation of neuroinflammation can intensify neuronal dysfunction and contribute to the occurrence of epilepsy. This review delves into the mechanisms associated with

关键词： axon guidance drug-resistant epilepsy epilepsy nerve regeneration nervous system diseases neural pathways neuroinflammatory diseases neuronal plasticity neurons synaptic remodeling

Topology Optimization of Truss Structures Based on Genetic Algorithm

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Topology Optimization of Truss Structures Based on Genetic A...

中国力学学会学术大会'2009

作者： Sun hao,liu yang School of Civil Engineering,Hohai University,Nanjing 210098,China,

This paper develops a genetic algorithm to optimize weight of truss in phase with discrete size, continuous dimension or topology *** on genetic algorithm,a mathematical model is detailed regarding some constraints in... 详细信息

关键词： genetic algorithm truss structure topology optimization coding mathematical model

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多光谱图像与全色图像的像素级融合研究

数据采集与处理 2003年第3期18卷 296-301页

作者：刘哲郝重阳刘晓翔樊养余西北工业大学电子与信息工程研究所西安710072

以高空间分辨率的全色图像与高光谱分辨率的多光谱图像进行像素级双源融合为例 ,详细地总结了卫星多源遥感图像融合领域像素级融合的步骤、基本融合模型和优缺点 ,重点分析了各种常见像素级融合方法的原理和特点 ,并归纳了像素级融合结... 详细信息

以高空间分辨率的全色图像与高光谱分辨率的多光谱图像进行像素级双源融合为例 ,详细地总结了卫星多源遥感图像融合领域像素级融合的步骤、基本融合模型和优缺点 ,重点分析了各种常见像素级融合方法的原理和特点 ,并归纳了像素级融合结果的主客观评价标准和评价方法 ,以及像素级融合的主要应用领域 ,最后讨论了像素级融合目前存在的问题和今后的发展方向。

关键词：遥感学数据融合图像融合遥感图像多光谱图像全色图像像素级融合图像处理

Ammonia pyrolysis oxidation excited by nanosecond pulsed discharge:Global/fluid models hybrid solution

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Journal of Energy Chemistry 2025年第1期100卷 385-396页

作者： Mingming Zhang Hanyu Wu Qi Chen Jiaxin yang Bonan liu School of Mechanical Electronic and Control Engineering Beijing Jiaotong University China University of Petroleum

The kinetic characteristics of plasma-assisted oxidative pyrolysis of ammonia are studied by using the global/fluid models hybrid solution ***,the stable products of plasma-assisted oxidative pyrolysis of ammonia are *** results show that the consumption of NH3/O2and the production of N2/H2change linearly with the increase of voltage,which indicates the decoupling of nonequilibrium molecular excitation and oxidative pyrolysis of ammonia at low ***,the detailed reaction kinetics mechanism of ammonia oxidative pyrolysis stimulated by a nanosecond pulse voltage at low pressure and room temperature is *** on the reaction path analysis,the simplified mechanism is *** detailed and simplified mechanism simulation results are compared with experimental data to verify the accuracy of the simplified ***,based on the simplified mechanism,the fluid model of ammonia oxidative pyrolysis stimulated by the nanosecond pulse plasma is established to study the pre-sheath/sheath behavior and the resultant consumption and formation of key *** results show that the generation,development,and propagation of the pre-sheath have a great influence on the formation and consumption of *** consumption of NH3by the cathode pre-sheath is greater than that by the anode pre-sheath,but the opposite is true for OH and O（1S）.However,within the sheath,almost all reactions do not ***,by changing the parameters of nanosecond pulse power supply voltage,it is found that the electron number density,electron current density,and applied peak voltages are not the direct reasons for the structural changes of the sheath and ***,the discharge interval has little effect on the sheath structure and gas mixture *** research results of this paper not only help to understand the kinetic promotion of non-equilibrium excitation in the process of oxidative pyrolysis but also help to explore th

关键词： Nanosecond pulsed discharge Ammonia Oxidative pyrolysis Fluid model Global model

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan yang Han Jia Tuo liu Yuzhen yang Jun yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter