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Surface Plasmon Resonance and Raman Scattering Activity of the Au/AgxO/Ag Multilayer Film

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Chinese Physics Letters 2014年第4期31卷 147-149页

作者： ZHONG Yu-Ting CHENG Zi-Qiang MA Liang wang Jia-Hong hao Zhong-hua wang Qu-Quan Key Laboratory of Artificial Micro- and Nano-structures of the Ministry of Education and School of Physics and Technology Wuhan University Wuhan 430072

The nanostructured Au/AgxO/Ag sandwich multilayer films on quartz substrates are prepared by the magnetron sputtering method. The morphology, plasmon resonance and surface enhanced Raman scattering （SERS） activi- ties of the multilayer films are studied. The resonant absorption wavelength of localized surface plasmon is tuned in a wide range from 618nm to 993nm by controlling the density of nanoparticles of Au and Ag. The SERS activity of the Au/AgxO/Ag multilayer films are enhanced over -10 times compared with those of bare Ag and bare Au films. These properties may find a potential application in biosensor and bioimaging.

关键词： SURFACE plasmon resonance RAMAN scattering SERS spectroscopy BIO-imaging sensors MAGNETRON sputtering

Fast magnetic reconstruction of the portal vein with allogeneic blood vessels in canines

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Hepatobiliary & Pancreatic Diseases International 2015年第3期14卷 293-299页

作者： Shan-Pei wang Xiao-Peng Yan Fei Xue Ding-Hui Dong Xu-Feng Zhang Feng Ma hao-hua wang Yi Lv Department of Hepatobiliary Surgery First Affiliated Hospital Medical School of Xi'an Jiaotong University Regenerative Medicine and Surgery Engineering Research Center of Shaanxi Province

BACKGROUND： The resection and reconstruction of large vessels, including the portal vein, are frequently needed in tumor resection. Warm ischemia before reconstruction might have deleterious effects on the function of some vital organs and therefore, how to reconstruct the vessels quickly after resection is extremely important. The present study was to introduce a new type of magnetic compression anastomosis （MCA） device to establish a quick non-suture anastomosis of the portal vein after resection in canines.

关键词： magnetic compression anastomosis portal vein reconstruction non-suture anastomosis

Magnetic-assisted laparoscopic liver transplantation in swine

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 340-346页

作者： Zhe Feng Shan-Pei wang hao-hua wang Qiang Lu Wei Qiao Kai-Ling wang Hong-Fan Ding Yue wang Rong-Feng wang Ai-hua Shi Bing-Yi Ren Yu-Nan Jiang Bin He Jia-Wei Yu Rong-Qian Wu Yi Lv Department of Hepatobiliary Surgery the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China National Local Joint Engineering Research Center for Precision Surgery&Regenerative Medicine Shaanxi Provincial Center for Regenerative Medicine and Surgical EngineeringInstitute of Advanced Surgical Technology and Engineeringthe First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China Department of Geriatric Surgery the First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061China Department of Hepatobiliary Surgery Shaanxi Provincial People’s HospitalXi’an 710000China Zonglian College Xi’an Jiaotong UniversityXi’an 710000China

Background:Although laparoscopic technology has achieved rapid development in the surgical field,it has not been applied to liver transplantation,primarily because of difficulties associated with laparoscopic vascular *** this study,we introduced a new magnetic-assisted vascular anastomosis technique and explored its application in laparoscopic liver transplantation in ***:Two sets of magnetic vascular anastomosis rings(MVARs)with different diameters were *** set was used for anastomosis of the suprahepatic vena cava(SHVC)and the other set was used for anastomosis of the infrahepatic vena cava(IHVC)and portal vein(PV).Six laparoscopic orthotopic liver transplantations were performed in *** liver was obtained via open *** was performed in the recipients through laparoscopic *** of the SHVC was performed using hand-assisted magnetic anastomosis,and the anastomosis of the IHVC and PV was performed by magnetic anastomosis with or without hand ***:Liver transplants were successfully performed in five of the six *** ultrasonographic examination showed that the portal inflow was ***,PV bending and blood flow obstruction occurred in one case because the MVARs were attached to each *** durations of loading of MVAR in the laparoscope group and manual assistance group for IHVC and PV were 13±5 vs.5±1 min(P<0.01)and 10±2 vs.4±1 min(P<0.05),*** durations of MVAR anastomosis in the laparoscope group and manual assistance group for IHVC and PV were 5±1 vs.1±1 min(P<0.01),and 5±1 vs.1±1 min(P<0.01),*** anhepatic phase was 43±4 min in the laparoscope group and 23±2 min in the manual assistance group(P<0.01).Conclusions:Our study showed that magnetic-assisted laparoscopic liver transplantation can be successfully carried out in pigs.

关键词： Liver transplantation Laparoscopy Magnetic surgery Vascular anastomosis

Tunable coupling between Xmon qubit and coplanar waveguide resonator

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Chinese Physics B 2019年第8期28卷 62-65页

作者： He-Kang Li Ke-Min Li Hang Dong Qiu-Jiang Guo Wu-Xin Liu Zhan wang hao-hua wang Dong-Ning Zheng Institute of Physics Chinese Academy of Sciences (CAS)Beijing 100190China Zhejiang Province Key Laboratory of Quantum Technology and Device Department of PhysicsZhejiang UniversityHangzhou 310027China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China CAS Center for Excellence in Topological Quantum Computation University of Chinese Academy of SciencesBeijing 100049China

Realization of a flexible and tunable coupling scheme among qubits is critical for scalable quantum information ***,we design and characterize a tunable coupling element based on Josephson junction,which can be adapted to an all-to-all connected circuit architecture where multiple Xmon qubits couple to a common coplanar waveguide *** coupling strength is experimentally verified to be adjustable from 0 MHz to about 40 MHz,and the qubit lifetime can still be up to 12μs in the presence of the coupling element.

关键词： superconducting Xmon qubit qubit-resonator coupling tunable coupling

Predictive and prognostic implications of 4E-BP1, Beclin-1, and LC3for cetuximab treatment combined with chemotherapy in advanced colorectal cancer with wild-type KRAS: Analysis from real-world data

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World Journal of Gastroenterology 2019年第15期25卷 1840-1852页

作者： Gui-Fang Guo Yi-Xing wang Yi-Jun Zhang Xiu-Xing Chen Jia-Bin Lu hao-hua wang Chang Jiang Hui-Quan Qiu Liang-Ping Xia VIP Department Sun Yat-sen University Cancer Center Collaborative Innovation Center for Cancer Medicine State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer Center Pathology Department Sun Yat-sen University Cancer Center

BACKGROUND Colorectal cancer(CRC) is one of the main causes of cancer-related deaths in China and around the world. Advanced CRC(ACRC) patients suffer from a low cure rate though treated with targeted therapies. The response rate is about 50% to chemotherapy and cetuximab, a monoclonal antibody targeting epidermal growth factor receptor(EGFR) and used for ACRC with wild-type KRAS. It is important to identify more predictors of cetuximab efficacy to further improve precise treatment. Autophagy, showing a key role in the cancer progression, is influenced by the EGFR pathway. Whether autophagy can predict cetuximab efficacy in ACRC is an interesting *** To investigate the effect of autophagy on the efficacy of cetuximab in colon cancer cells and ACRC patients with wild-type *** ACRC patients treated with cetuximab plus chemotherapy, with detailed data and tumor tissue, at Sun Yat-sen University Cancer Center from January 1, 2005,to October 1, 2015, were studied. Expression of autophagy-related proteins[Beclin1, microtubule-associated protein 1 A/B-light chain 3(LC3), and 4 Ebinding protein 1(4 E-BP1)] was examined by Western blot in CRC cells and by immunohistochemistry in cancerous and normal tissues. The effect of autophagy on cetuximab-treated cancer cells was confirmed by MTT assay. The associations between Beclin1, LC3, and 4 E-BP1 expression in tumor tissue and the efficacy of cetuximab-based therapy were *** In CACO-2 cells exposed to cetuximab, LC3 and 4 E-BP1 were upregulated, and P62 was downregulated. Autophagosome formation was observed, and autophagy increased the efficacy of cetuximab. In 68 ACRC patients,immunohistochemistry showed that Beclin1 levels were significantly correlated with those of LC3(0.657, P < 0.001) and 4 E-BP1(0.211, P = 0.042) in ACRC ***3 was significantly overexpressed in tumor tissues compared to normal tissues(P < 0.001). In 45 patients with wild-type KRAS, the expression levels of these three pro

关键词： 4E-binding protein 1 Beclin-1 Microtubule-associated protein 1A/B-light chain 3 Advanced colorectal cancer Cetuximab efficacy Prognosis

Hepatic volumetry with PhotoShop in personal computer

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Hepatobiliary & Pancreatic Diseases International 2004年第1期3卷 82-85页

作者： Yi Lu, Zheng Wu, Chang Liu and hao-hua wang Xi’an, China Department of Hepatobiliary Surgery, First Hospital, Xi’ an Jiaotong University, Xi’ an 710061 , China Department of Hepatobiliary Surgery First Hospital Xi'an Jiaotong University Xi'an 710061 China. luyi169@***

BACKGROUND: Convenient way to clarify liver volum or tumor volume in the liver is eagerly demanded by hepa tobiliary surgeons, for so many aspects of clinical wor need to know the liver volumetry. At present, some me thods have been used to measure the liver volumetry, suc as computed tomography (CT) scans, three-dimensiona ultrasound volumetric system [1] and 3-dimensional sono graphy[2,3] et al. But enough volumetric information wa failed to obtain by surgeons and a new way of measurin the liver volumetry that can be operated by themselves i exigent. Whereas we devise a new method of using Photo Shop in personal computer to measure the liver volumetry METHODS: A piece of whole CT film was transformed t a high quality digitized image by digital camera or scanne and then the digitized image was conducted as JPEG file in to personal computer. The JPEG image file of CT film wa opened by PhotoShop. Determining the edge of interested areas, and the data of pixel values of the interested areas di vided by 1 cm2 pixel value will produce the actual area with the unit of square centimeter. If section thickness of CT scan is 1 cm, the sum of the areas of the liver or tumor in all sections naturally is the volume of the liver or tumor. RESULTS: Comparison of 10 hepatic volumes gained by this method and those gained by the GE Prospeed CT se showed a good relativity between the two groups. The vo lumes of three right lobes were calculated by this method before lobectomy and their real volumes were obtained postoperatively by a volumenometer. Their variation wa limited to 5%. CONCLUSIONS: Hepatic volume obtained by PhotoShop is reliable. This method can be used to measure hepati volume perfectly to meet clinical demand, and many pa rameters such as liver resection rate, graft volume can be achieved. The disadvantage of this method is the step o copying the pixel value from PhotoShop to Microsoft Ex cel.

关键词： hepatic volumetry PhotoShop

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie wang Wei wang Xuheng Chen Junfang Bao Qiuyue hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

Choledochojejunostomy with an innovative magneticcompressive anastomosis:How to determine optimalpressure?

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World Journal of Gastroenterology 2016年第7期22卷 2326-2335页

作者： Fei Xue Hong-Chang Guo Jian-Peng Li Jian-Wen Lu hao-hua wang Feng Ma Ya-Xiong Liu Yi Lv Department of Hepatobiliary Surgery First Affiliated HospitalXi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina XJTU Research Institute of Advanced Surgical Technology and Engineering Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Regenerative Medicine and Surgery Engineering Research Center of Shaanxi Province Xi’an 710061Shaanxi ProvinceChina School of Mechanical Engineering Xi’an Polytechnic UniversityXi’an 710048Shaanxi ProvinceChina State Key Laboratory of Mechanical System Engineering Xi’an 710049Shaanxi ProvinceChina

AIM: To investigate the optimal magnetic pressure and provide a theoretical basis for choledochojejunostomy magnetic compressive anastomosis(magnamosis).METHODS: Four groups of neodymium-iron-boron magnets with different magnetic pressures of 0.1, 0.2, 0.3 and 0.4 MPa were used to complete the choledochojejunostomy magnamosis. Twenty-six young mongrel dogs were randomly divided into five groups: four groups with different magnetic pressures and 1 group with a hand-suture anastomosis. Serum bilirubin levels were measured in all groups before and 1 wk, 2 wk, 3 wk, 1 mo and 3 mo after surgery. Daily abdominal X-ray fluoroscopy was carried out postoperatively to detect the path and the excretion of the magnet. The animals were euthanized at 1 or 3 mo after the operation, the burst pressure was detected in each anastomosis, and the gross appearance and histology were compared according to the ***: The surgical procedures were all successfully performed in animals. However, animals of group D(magnetic pressure of 0.4 MPa) all experienced complications with bile leakage(4/4), whereas half of animals in group A(magnetic pressure of 0.1 MPa) experienced complications(3/6), 1 animal in the manual group E developed anastomotic stenosis, and animals in group B and group C(magnetic pressure of 0.2 MPa and 0.3 MPa, respectively) all healed well without complications. These results also suggested that the time required to form the stoma was inversely proportional to the magnetic pressure; however, the burst pressure of group A was smaller than those of the other groups at 1 mo(187.5 ± 17.7 vs 290 ± 10/296.7 ± 5.7/287.5 ± 3.5, P < 0.05); the remaining groups did not differ significantly. A histologic examination demonstrated obvious differences between the magnamosis groups and the hand-sewn ***: We proved that the optimal range for choledochojejunostomy magnamosis is 0.2 MPa to 0.3 MPa, which will help to improve the clinical application of this techni

关键词： Choledochojejunostomy Magnetic compressiveanastomosis Optimal range Pressure intensity Magnetic pressure

Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity

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World Journal of Gastroenterology 2025年第1期31卷 79-92页

作者： Dan Hu Yue Li hua Zhang Lian-Lian wang Wen-Wen Liu Xin Yang Ming-Zhao Xiao hao-Ling Zhang Juan Li Department of Nursing The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Nursing National Clinical Research Center for Child Health and DisordersMinistry of Education Key Laboratory of Child Development and DisordersChildren’s Hospital of Chongqing Medical UniversityChongqing 400014China Department of Gastrointestinal Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China Department of Biomedical Science Advanced Medical and Dental InstituteUniversity Sains MalaysiaPenang 13200Malaysia Academic Affairs Office The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social ***,these survivors encounter significant challenges during their RTW ***,scientific research is necessary to explore the barriers and facilitating factors of returning to work for young and middle-aged CRC *** To examine the current RTW status among young and middle-aged CRC survivors and to analyze the impact of RTW self-efficacy(RTW-SE),fear of progression(FoP),eHealth literacy(eHL),family resilience(FR),and financial toxicity(FT)on their RTW *** A cross-sectional investigation was adopted in this *** September 2022 to February 2023,a total of 209 participants were recruited through a convenience sampling method from the gastrointestinal surgery department of a class A tertiary hospital in *** investigation utilized a general information questionnaire alongside scales assessing RTW-SE,FoP,eHL,FR,and *** analyze the factors that influence RTW outcomes among young and middle-aged CRC survivors,Cox regression modeling and Kaplan-Meier survival analysis were *** A total of 43.54%of the participants successfully returned to work,with an average RTW time of 100 *** regression univariate analysis revealed that RTW-SE,FoP,eHL,FR,and FT were significantly different between the non-RTW and RTW groups(P<0.05).Furthermore,Cox regression multivariate analysis identified per capita family monthly income,job type,RTW-SE,and FR as independent influencing factors for RTW(P<0.05).CONCLUSION The RTW rate requires further *** levels of RTW-SE and FR were found to significantly increase RTW among young and middle-aged CRC *** professionals should focus on modifiable factors,such as RTW-SE and FR,to design targeted RTW support programs,thereby facilitating their timely reintegration into mainstream society.

关键词： Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity