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食品安全导刊 2024年第9期 161-163页

作者：梁好芜湖市产品质量监督检验所安徽芜湖241000

食品快检技术在食品检测领域应用广泛,是食品安全监管的重要技术支撑。本文简要概述食品快检技术发展背景及应用现状,分析、归纳食品快检技术在实际应用中存在的问题,并提出了相应的对策,以期助力食品快检技术在食品检测中更好地发挥作... 详细信息

食品快检技术在食品检测领域应用广泛,是食品安全监管的重要技术支撑。本文简要概述食品快检技术发展背景及应用现状,分析、归纳食品快检技术在实际应用中存在的问题,并提出了相应的对策,以期助力食品快检技术在食品检测中更好地发挥作用,确保食品安全。

关键词：食品安全快速检测问题对策

rt-PA静脉溶栓治疗伴有HMCAS急性脑梗死患者的临床效果及对血清t-PA、PAI-1水平和免疫功能的影响

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临床医学研究与实践 2024年第12期9卷 52-55页

作者：梁浩鹿邑县人民医院神经内科一病区河南周口477299

目的探讨重组组织型纤溶酶原激活物(rt-PA)治疗伴有大脑中动脉高密度征(HMCAS)急性脑梗死患者的临床效果及对血清组织型纤溶酶原激活物(t-PA)、纤溶酶原激活物抑制物1(PAI-1)水平和免疫功能的影响。方法选取2020年3月至2022年6月在我院... 详细信息

目的探讨重组组织型纤溶酶原激活物(rt-PA)治疗伴有大脑中动脉高密度征(HMCAS)急性脑梗死患者的临床效果及对血清组织型纤溶酶原激活物(t-PA)、纤溶酶原激活物抑制物1(PAI-1)水平和免疫功能的影响。方法选取2020年3月至2022年6月在我院治疗的132例伴有HMCAS急性脑梗死患者的临床资料进行研究,根据治疗方案将其分为对照组(n=66)和观察组(n=66)。对照组给予常规治疗,观察组在此基础上给予rt-PA静脉溶栓治疗。比较两组的治疗效果。结果治疗7 d后,两组的美国国立卫生研究院卒中量表(NIHSS)评分均降低,且观察组显著低于对照组(P<0.05)。治疗7 d后,观察组的t-PA水平显著高于对照组,PAI-1水平显著低于对照组(P<0.05)。治疗7 d后,两组的CD3^(+)、CD4^(+)、免疫球蛋白G(IgG)和免疫球蛋白M(IgM)水平高于治疗前,且观察组显著高于对照组(P<0.05)。观察组的Barthel指数评分、改良Rankin量表(mRS)评分0~2分占比明显高于对照组(P<0.05)。结论rt-PA静脉溶栓治疗伴有HMCAS急性脑梗死效果较好,可有效改善患者t-PA、PAI-1水平,提升免疫功能,且安全性较高。

关键词：重组组织型纤溶酶原激活物大脑中动脉高密度征急性脑梗死免疫功能静脉溶栓

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深井基坑分段开挖方法数值模拟分析

广州建筑 2024年第3期52卷 1-4页

作者：梁浩中铁十一局集团第四工程有限公司武汉441300

为研究大“长宽比”深井基坑使用分段依次开挖的方式修建深基坑的剪应变和塑性区变化,文章依托江心洲中间风井基坑工程,利用FLAC3D软件对基坑开挖过程进行模拟,分析采用分段依次开挖对大“长宽比”深井基坑的施工过程产生的影响。研究... 详细信息

为研究大“长宽比”深井基坑使用分段依次开挖的方式修建深基坑的剪应变和塑性区变化,文章依托江心洲中间风井基坑工程,利用FLAC3D软件对基坑开挖过程进行模拟,分析采用分段依次开挖对大“长宽比”深井基坑的施工过程产生的影响。研究结果表明:基坑最大剪应变主要发生在基坑内部的“临空”边缘面;基坑开挖过程的模拟结束后基坑内现存的剪切破坏区主要存在于开挖基坑与地连墙边缘接缝处,而现存的拉伸破坏区主要存在于开挖基坑的临空边缘处;地下连续墙周围塑性区较少。在使用分段依次开挖方法进行基坑施工时,应尤其注意基坑内部的临空边缘面,避免发生垮塌危害;同时地下连续墙可以有效避免了基坑以外土层的坍塌陷落,在控制成本的情况下应尽量使用。

关键词：深井基坑分段依次开挖剪应力变化塑性区变化

Optical implementation of quantum random walks using weak cross-Kerr media

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Chinese Science Bulletin 2011年第20期56卷 2088-2091页

作者： WANG Chuan LI YanSong hao liang School of Science Beijing University of Posts and TelecommunicationsBeijing 100876China Key Laboratory of Optical Communication and Lightwave Technologies Beijing University of Posts and TelecommunicationsBeijing 100876China Department of Physics Tsinghua UniversityBeijing 100084China

Weak cross-Kerr media provides additional degrees of freedom of qubits in quantum information processing.In this paper,by exploiting weak cross-Kerr nonlinearity,we propose an optical implementation scheme of one-dimensional quantum random walks. The random walks are described by the interaction of single photons with cross-Kerr media.The proposed scheme can also be used to implement one-dimensional quantum random walks on an infinite line.

关键词：随机游动光量子媒体 Kerr非线性量子信息处理相互作用克尔介质量子位

“一主线、双目标、多载体”专创融合模式研究

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辽宁高职学报 2024年第3期26卷 1-3,70页

作者：梁浩沈阳职业技术学院辽宁沈阳110045

高职院校作为技术技能型人才培养的主阵地,需要培养学生的创新意识和创业能力,协调好创新创业教育与专业教育之间的关系,将创新创业教育与专业教育有机融合,促进学生就业与创业。目前,专创融合在高职院校的人才培养体系中还存在衔接不... 详细信息

高职院校作为技术技能型人才培养的主阵地,需要培养学生的创新意识和创业能力,协调好创新创业教育与专业教育之间的关系,将创新创业教育与专业教育有机融合,促进学生就业与创业。目前,专创融合在高职院校的人才培养体系中还存在衔接不顺畅、教师队伍数量不足、实践平台建设不完善等现实问题。探索构建“一主线、双目标、多载体”的专创融合培养模式对提升创新型技术技能人才培养质量,促进学生全面发展皆具有实践意义。

关键词：专创融合高职院校人才培养创新创业

Analysis of Sheet Curvature in Asymmetrical Cold Rolling

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Journal of Iron and Steel Research(International) 2013年第5期20卷 34-37页

作者： hao liang DI Hong-shuang GONG Dian-yao State Key Laboratory of Rolling Technology and Automation Northeastern University

In asymmetric cold rolling, the workpiece is often bent downwards or upwards. A two-dimensional explicit dynamic finite element model with Arbitrary Lagrangian Eulerian （ALE） adaptive meshing technique has been employed to simulate asymmetrical sheet rolling, in which asymmetrical conditions are here due to different roll radii. To validate the simulation, the results of simulation and experiment are compared. Effects of asymmetry due to roll radii mismatch on the normal and shear distributions and on sheet curvature variations are discussed. An optimum roll radii ratio could be found to produce flat sheet. Trials were conducted to investigate the effectiveness of roll radii mismatch as an approach of sheet curvature control.

关键词： asymmetrical rolling finite element method radii ratio sheet curvature

Hydrogen-induced Modification in the Deformation and Fracture of a Precipitation-hardened Fe-Ni Based Austenitic Alloy

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Journal of Materials Science & Technology 2014年第11期30卷 1155-1159页

作者： Mingjiu Zhao Zifeng Guo Shenghu Chen hao liang Lijian Rong Institute of Metal Research Chinese Academy of Sciences Shougang Research Institute of Technology Shougang Group Institute of System Engineering China Academy of Engineering and Physics

Hydrogen-induced modification in the deformation and fracture of a precipitation-hardened Fe-Ni based austenitic alloy has been investigated in the present study by means of thermal hydrogen charging experiment, tensile tests, scanning electron microscopy （SEM） and transmission electron microscopy （TEM）. It is found that the γ＇ particles are subjected to the multiple shearing by dislocations during plastic deformation, which promotes the occurrence of the dislocation planar slip. Moreover, the alloy will be enhanced by hydrogen resulting in the formation of strain localization at macroscale. So, the mechanisms of deformation and fracture in the alloy have been proposed in terms of serious hydrogen-induced planar slip at microscale which can lead to macroscopic strain localization.

关键词： Hydrogen Deformation Fracture Precipitation-hardened austenitic alloy

Influence of sulfuric-acid-bath pretreatment and soaked in sulfuric acid on surface morphology and photocatalytic activity of titania coatings

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Science China(Technological Sciences) 2020年第12期63卷 2657-2663页

作者： GUAN SuJun hao liang KASUGA Shota YOSHIDA Hiroyuki CHENG YanLing LU Yun Department of Physics Tokyo University of ScienceTokyo 162-8601Japan College of Mechanical Engineering Tianjin University of Science and TechnologyTianjin 300222China Department of Mechanical Engineering Chiba UniversityChiba 263-8522Japan Chiba Industrial Technology Research Institute Chiba 263-0016Japan Beijing Key Laboratory of Biomass Waste Resource Utilization Beijing Union UniversityBeijing 100023China

Titania(TiO2) photocatalyst coatings have been fabricated by the low-cost approach of sulfuric-acid-bath pretreatment(SAP)followed soaked in sulfuric acid(SA) at room temperature then oxidated in air. The influence of the SAP and soaked conditions on the surface morphology and photocatalytic activity of TiO2 on Ti coatings was investigated. With different SAP conditions,the surface morphologies of the TiO2 on Ti coatings clearly show the formed porous-like structure. With higher SA concentration,the porous-like structure becomes obviously. With extending soaked time,the porous-like structure tends to disappear. Raman spectroscopy reveals that the formed TiO2 coatings are with mixed-phase of anatase and rutile. Compared with those of SA concentration and SAP time,the influence of the soaked time on the phase transformation is obvious. Notably,the photocatalytic activity of TiO2 on Ti coatings had been efficiently enhanced by extending the soaked time,compared with those of higher SA concentration and longer SAP time. The enhanced photocatalytic activity of TiO2 on Ti coatings could be related with the changed surface morphology,mixed-phase of anatase and rutile,and formed hydroxyl groups.

关键词： TiO2 coatings sulfuric-acid-bath pretreatment mixed-phase photocatalytic activity surface morphology

Hydroxysafflor yellow A improves learning and memory in a rat model of vascular dementia by increasing VEGF and NR1 in the hippocampus

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Neuroscience Bulletin 2014年第3期30卷 417-424页

作者： Nan Zhang Mengya Xing Yiyi Wang hao liang Zhuo Yang Fudong Shi Yan Cheng Department of Neurology Tianjin Medical University General Hospital Tianjin Neurological Institute Key Laboratory of Post-traumatic Neuro-repair and Regeneration in the Central Nervous System Ministry of Education Tianjin Key Laboratory of Injuries Variations and Regeneration of the Nervous System Tianjin Haihe Hospital Nankai University

Hydroxysafflor yellow A （HSYA） has angiogenesis- regulating and neuro-protective effects, but its effects on vascular dementia （VaD） are unknown. In this study, 30 adult Sprague-Dawley rats were. randomly allocated to five groups： normal, sham-operation, VaD alone （bilateral carotid artery occlusion）, VaD plus saline （control）, and VaD plus HSYA. One week after operation, the HSYA group received one daily tail-vein injection of 0.6 mg/100 g HSYA for two weeks. Five weeks after operation, the spatial memory of all five groups was evaluated by the water maze task, and synaptic plasticity in the hippocampus was assessed by the long-term potentiation （LTP） method. Vascular endothelial growth factor （VEGF） and N-methyi-D- aspartic acid receptor 1 （NR1） expression in the hippocampus was detected via Western blot. We found that, compared with the group with VaD alone, the group with HSYA had a reduced escape latency in the water maze （P 〈0.05）, and the LTP at CA3- CA1 synapses in the hippocampus was enhanced （P 〈0.05）. Western blot in the late-phase VaD group showed slight up-regulation of VEGF and down- regulation of NR1 in the hippocampus, while HSYA significantly up-regulated both VEGF and NRI. These results suggested that HSYA promotes angiogenesis and increases synaptic plasticity, thus improving spatial learning and memory in the rat model of VaD.

关键词： vascular dementia hydroxysafflor yellow A long-term potentiation NMDA receptor vascular endothelial growth factor

Development of Fully-Distributed Fiber Sensors Based on Brillouin Scattering

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Photonic Sensors 2011年第1期1卷 54-61页

作者： Xuping ZHANG Yuangang LU Feng WANG hao liang Yixin ZHANG Institute of Optical Communication Engineering Nanjing UniversityNanjing 210093China

Brillouin scattering based optical fiber sensors(BOFS)have the unique advantages over other sensors such as long distance,fully distributed,and multi-parameter sensing.The progresses on the development of BOFS technology in Nanjing University are reviewed.The key technologies to make BOFS with ultra-long distance,high spatial resolution,and fast measuring speed are discussed and realized.

关键词： Brillouin scattering fully distributed optical fiber sensor Brillouin optical time domain reflectometry strain monitoring