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Selection for production-related traits in Pelargonium zonale: improved design and analysis make all the difference

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Horticulture Research 2017年第1期4卷 365-373页

作者： Heike Molenaar martin Glawe Robert Boehm hans-peter Piepho Institute of Crop Science University of HohenheimBiostatistics UnitStuttgart70599Germany Klemm+Sohn GmbH&Co.KG Stuttgart70378Germany

Ornamental plant variety improvement is limited by current phenotyping approaches and neglected use of experimental *** present study was conducted to show the benefits of using an experimental design and corresponding analysis in ornamental breeding regarding simulated response to selection in Pelargonium zonale for production-related *** required establishment of phenotyping protocols for root formation and stem cutting counts,with which 974 genotypes were assessed in a two-phase experimental *** present paper evaluates this *** possibility of varietal improvement through indirect selection on secondary traits such as branch count and flower count was assessed by genetic *** response to selection varied greatly,depending on the genotypic variances of the breeding population and traits.A varietal improvement of over 20%is possible for stem cutting count,root formation,branch count and flower *** contrast,indirect selection of stem cutting count by branch count or flower count was found to be *** established phenotypic protocols and two-phase experimental designs are valuable tools for breeding of ***.

关键词： breeding traits branch

Linear and angular momenta in tightly focused vortex segmented beams of light(Invited Paper)

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Chinese Optics Letters 2017年第3期15卷 7-11页

作者： martin Neugebauer Andrea Aiello peter Banzer Max Planck Institute for the Science of Light Staudtstr. 2 Erlangen D-91058 Germany Institute of Optics Information and Photonics University Erlangen-Nuremberg Staudtstr. 7/B2 Erlangen D-91058 Germany

We investigate the linear momentum density of light, which can be decomposed into spin and orbital parts, in the complex three-dimensional field distributions of tightly focused vortex segmented beams. The chosen angular spectrum exhibits two spatially separated vortices of opposite charge and orthogonal circular polarization to generate phase vortices in a meridional plane of observation. In the vicinity of those vortices, regions of negative orbital linear momentum occur. Besides these phase vortices, the occurrence of transverse orbital angular momentum manifests in a vortex charge-dependent relative shift of the energy density and linear momentum density.

关键词： Invited Paper VSB Linear and angular momenta in tightly focused vortex segmented beams of light

Optimization of product characteristics of porous carbon agglomerates using a design of experiments in fluidized bed agglomeration

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Particuology 2024年第6期89卷 258-269页

作者： martin Oelofse Robert Rack Marcelle Hilden peter Langguth Department of Pharmaceutical Technology and Biopharmaceutics Johannes Gutenberg UniversityMainzGermany Carbon Advanced Solutions GmbH HeuchelheimGermany

Spraying parameters during particle agglomeration processes can affect the agglomeration kinetics and particle *** study was conducted to better understand the influence of the spraying parameters in a fluidized bed wet agglomeration process,and the influence on the stability characteristics of carbon tablets.A formulation based on fine carbon and peroxide powder,as well as carboxymethyl cellulose as a binder,was used to produce agglomerates in a first production *** in a second production step carbon tablets with a high porosity were molded for the customer goods *** optimization of the compressive strength of these carbon tablets was the goal of the *** agglomerates were produced with a laboratory scale granulator called“ProCell”and were compressed with a five-cavity mechanical *** screening of the agglomeration process parameters and their influence on the agglomerates quality,as well as the performance characteristics of the carbon tablets,were investigated using a multilevel factorial *** experimental runs were done by varying atomized air pressure and feed rate of the *** was determined by the design *** findings of the statistical trials showed that low atomized air pressure and a low feed rate lead to a higher tablet compressive strength.

关键词： Wet agglomeration Fluidized bed Design of experiments Carbon agglomerates and tablets

Diagnostic tools for fecal incontinence: Scoring systems are the crucial first step

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World Journal of Gastroenterology 2024年第6期30卷 516-522页

作者： peter Liptak martin Duricek peter Banovcin Clinic of Internal Medicine-Gastroenterology University Hospital in MartinJessenius Faculty of Medicine in MartinComenius UniversityMartin 03601Slovakia

The main aim of this editorial is to comment on the recent article published by Garg et al in the World Journal of Gastroenterology 2023;29:*** original research presents a new scoring system for fecal *** incontinence is a chronic disease with a severe impact on the quality of life of the *** social stigmatization often leads to significant underreporting of the condition even during visits to a specialist and could lead to further misman-agement or non-existent management of the *** important fact is that patients are often unable to describe their condition when not asked precisely defined *** problem is partially resolved by scoring *** scoring systems are commonly used;however,each of them has their *** example,the absence of different kinds of leakage besides flatus and stool could further lead to underscoring the incontinence ***,there has long been a call for a more precise scoring *** correct identification of the presence and severity of fecal incontinence is paramount for further diagnostic approach and for choosing the appropriate therapy *** editorial describes fecal incontinence,its effect on quality of life in general and further evaluates the diagnostic approach with a particular focus on symptom scoring systems and their implications for clinical practice.

关键词： Incontinence Fecal Scoring system Questionary Quality of life

Avoiding hepatic metastasis naturally: Lessons from the cotton top tamarin(Saguinus oedipus )

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World Journal of Gastroenterology 2016年第24期22卷 5479-5494页

作者： martin Tobi peter Thomas Daniel Ezekwudo Department of Surgery Aleda E. Lutz VAMC Internal Medicine Disciplines Central Michigan University College of Medicine Department of Surgery Creighton University School of Medicine

Much has been written about hepatic metastasis and animal models abound. In terms of the human experience, progress in treating this final common pathway, a terminal event of many human malignancies has been relatively slow. The current thinking is that primary prevention is best served by early detection of cancer and eradication of early stage cancers by screening. Some cancers spread early in their course and the role of screening may be limited. Until relatively recently there has not been a pathfinder model that makes the evasion of this unfortunate event a reality. This review discusses such an animal model and attempts to relate it to human disease in terms of intervention. Concrete proposals are also offered on how scientists may be able to intervene to prevent this deadly progression of the cancer process.

关键词： Cotton top tamarin Hepatic metastasis Carcinoembryonic antigen Fibulin-5 Common marmoset

Absolute characterization of high numerical aperture microscope objectives utilizing a dipole scatterer

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Light(Science & Applications) 2021年第12期10卷 2342-2348页

作者： Jörg S.Eismann martin Neugebauer Klaus Mantel peter Banzer Institute of Physics University of GrazNAWI GrazUniversitätsplatz 58010 GrazAustria Max Planck Institute for the Science of Light Staudtstr.291058 ErlangenGermany Institute of Optics Information and PhotonicsUniversity Erlangen-NurembergStaudtstr.7/B291058 ErlangenGermany

Measuring the aberrations of optical systems is an essential step in the fabrication of high precision optical *** a characterization is usually based on comparing the device under investigation with a calibrated reference ***,when working at the cutting-edge of technology,it is increasingly difficult to provide an even better or well-known reference *** this manuscript we present a method for the characterization of high numerical aperture microscope objectives,functioning without the need of calibrated reference *** technique constitutes a nanoparticle,acting as a dipole-like scatterer,that is placed in the focal volume of the microscope *** light that is scattered by the particle can be measured individually and serves as the reference wave in our *** the well-characterized scattered light as nearly perfect reference wave is the main idea behind this manuscript.

关键词： characterization scatter scattered

Assessing Possibilities and Limitations for Biomarker Analyses on Outcrop Samples:A Case Study on Carbonates of the Shibantan Member (Ediacaran Period, Dengying Formation, South China)

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Acta Geologica Sinica(English Edition) 2014年第6期88卷 1696-1704页

作者： Jan-peter DUDA Volker THIEL Joachim REITNER martin BLUMENBERG Geoscience Centre Geobiology Group Georg-August-University GttingenGoldschmidtstr.337077 Gttingen Germany Federal Institute for Geosciences and Natural Resources (BGR) Stilleweg 2 30655 Hannover Germany

The Shibantan Member（Dengying Formation, South China） represents one of only two carbonate settings with Ediacara-type organisms and offers a rare opportunity to study the biogeochemistry of these ecosystems. To evaluate possibilities and limitations for future biomarker studies on fossil-bearing outcrop samples of the Shibantan Member, we analysed the spatial distribution of hydrocarbons in extractable organic matter（i.e. bitumen） on a millimetre scale. Our study demonstrates that the sample and most likely also other rocks from the same setting are contaminated with petroleum-derived compounds that bear the potential for erroneous interpretations in palaeo-reconstructions. The contamination was revealed by distribution patterns and amounts of extractable n-alkanes and acyclic isoprenoids. The contamination is linked to the external weathering surfaces but also to cracks within the rock, and the extent most likely depends on concentration gradients between these contamination sources. Here we show that contamination can successfully be distinguished from syngenetic signals obtained from non-extractable organic matter（i.e. kerogen） using catalytic hydropyrolysis（Hy Py）. However, we observed that decalcification is necessary to achieve sufficient yields of kerogen-bound hydrocarbons and to avoid artificial alteration of the biomarker signals due to matrix effects.

关键词： Ediacaran biomarkers contamination syngeneity slice-experiments catalytic hydropyrolysis(HyPy)

Preliminary assessment of the solar resource in the United Kingdom

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Clean Energy 2018年第2期2卷 112-125页

作者： Mahmoud Dhimish Violeta Holmes peter Mather martin Sibley Laboratory of Photovoltaics School of Computing and EngineeringUniversity of HuddersfieldUnited Kingdom

Solar radiation resources data are the foundation of knowledge for programs of large-scale deployment of solar energy *** article summarizes the analysis of a new weather stations network in the United *** analysis used three years(January 2015-December 2017)of data from 27 weather stations distributed across the *** data comprises global horizontal irradiance(GHI),diffuse horizontal irradiance,direct normal irradiance and the ambient *** design,implementation and data quality assurance are described to document the network extent and *** all observed datasets,we found that Plymouth(located in southwest England)has the dominant GHI and ambient temperature among all other 26 *** least GHI is observed for Aberdeen(located in northeast Scotland)estimated at 77.3 kWh/*** least average ambient temperature is equal to 9.1℃;the data were detected by the weather station located in the capital of Scotland(Edinburgh).Although continued measurements are needed to understand the interannual resource variability,the current study should have significant applications for preliminary technology selection,power plant modeling and resource forecasting.

关键词： solar resources GHI ambient temperature United Kingdom

R0 Liver Resection should be a First-line Treatment for Selected Patients with Intermediate Hepatocellular Cancer

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Journal of Clinical and Translational Hepatology 2023年第4期11卷 757-760页

作者： martin Janicko Sylvia Drazilova peter Jarcuska Second Department of Internal Medicine PJ Safarik UniversityFaculty of Medicine and Pasteur University HospitalKosiceSlovakia

Introduction Hepatocellular cancer(HCC)is the sixth most common malignancy worldwide and the second most common cause of mortality among all *** HCCs occur in cirrhotic livers,but an increasing proportion of cases occur in livers without cirrhosis,particularly in Hepatitis B virus infection or in nonalcoholic fatty liver disease patients.^(1) Liver resection(LR)is the treatment of choice in most noncirrhotic patients,therefore most discussion is related to patients with *** survival(OS)depends on the stage at the time of *** Clinic Liver Cancer(BCLC)staging is the currently preferred staging system for HCC in Europe and North America^(2) Only a small proportion of patients with HCC are diagnosed at a very early or early stage(BCLC 0-A)when curative treatment,including LR,is generally recommended.

关键词： Liver Cancer mortality