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Occurrence of trichoepithelioma in a cat:Histopathologic and immunohistochemical study

Asian Pacific Journal of Tropical Biomedicine 2013年第5期3卷 413-415页

作者： Abbas Tavasoli hannaneh golshahi Maryam Nobakht Rad Afra Taymouri Department of Pathology Faculty of Veterinary MedicineUniversity of Tehran Division of General Surgery Department of SurgeryFirouzgar Hospital Faculty of Veterinary Medicine University of Tehran

Trichoepitheliomas are benign follicular appendage tumors with differentiation to all three segments of the hair follicle.A 2 years old female domestic short hair cat presented with a mass on the *** mass was surgically excised and for histopathologic and immunohistochemical studies,was sent to Department of ***,the tumor was encapsulated and consisted of many islands of follicular epithelium and also cysts structures which varied in size and *** cells of epithelium islands were round to oval and had variable amounts of slightly,eosinophilic cytoplasm and euchromatic *** cystic structures were lined by a complex layer of squamous ***,cells under went an abrupt transition between basal layers and keratinization without the development of a granular cell *** tendency of malignancy was seen in this *** to mentioned characteristics,trichoepitlielioma was *** immunohistochemical study it was confirmed that this tumor had epithelial origin because squamous tumor cells reacted with the pan-cytokeratin *** expression of p-catenin was predominately cytoplasmic and also together with numerous positive nuclei but membranous expression was *** of neoplastic cells with P-catenin expression was more than 75%and labeling intensity was strong in both cytoplasm and *** to author's knowledge,this is the first report of trichoepithelioma in cat in Iran and also investigation of P-catenin expression in feline trichoepithelioma in veterinary literature.

关键词： Trichoepithelioma Catβ-catenin Pan-cytokeratin

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