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Journal of Energy and Power Engineering 2013年第4期7卷 705-710页

作者： Takahiro Yoshida Tetsuya sano Takashi Nomura Hideki Gensai Hiroki Watada Seiji Ohara Forestry and Forest Products Research Institute Tsukuba 305-8687 Japan Fukui Prefectural Green Center Sakai 910-0336 Japan

In order to upgrade the conventional wood pellet, Japanese softwood and hardwood chips were torrefied at around 200-350℃, and pelletized. The characteristics of the torrefied material/pellets such as their calorific value, grinding energy, pelletizing energy and elemental composition, were also evaluated in this study. The calorific value rose with increasing torrefaction temperature and exceeded 25 MJ/kg （an increase of nearly 40% compared to the untreated state） for torrefaction at around 350℃. The grinding energy greatly decreased with increasing torrefaction temperature, and the reduction was larger for Japanese oak hardwood chips. The pelletization energy for the torrefied material tended to be slightly smaller than in the untreated case. People named such torrefied pellet as ＂hyper wood pellet＂.

关键词： Wood pellets torrefaction calorific value.

Evaluation of Delivery Analysis to Detect Intrafractional Motion during Tomotherapy

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2019年第4期8卷 225-235页

作者： kazuo Tarutani Masao Tanooka keisuke sano Okada Wataru Masayuki Fujiwara koichiro Yamakado Department of Radiology Hyogo College of Medicine Nishinomiya Japan Japan Organization of Occupational Health and Safety kansai Rousai Hospital Amagasaki Japan Department of Radiotherapy Takarazuka City Hospital Takarazuka Japan

The purpose of this study was to investigate the ability of a management system (Delivery Analysis: DA) to detect intrafractional motion during intensity-modulated radiation therapy (IMRT) in tomotherapy mode. Tomotherapy has made it possible to manage internal movements during treatment using software DA, which quantifies using the information of the passing dose obtained during the radiation treatment of patients. First, three treatment plans for the test were created (lumbar spine, prostate, and femur). Second, a pelvis phantom was moved in the X, Y, and Z directions, and a sinogram was acquired. The magnitudes of the movements were 3 mm, 5 mm, and 10 mm, respectively. Finally, the ability of DA to detect the motion was evaluated by comparing the sinogram obtained by moving the phantom with a reference sinogram obtained without movement. The sensitivity of DA could be detected with a shift amount of 3 mm (gamma analysis tolerance 0.3 mm/0.3%). The average gamma analysis of each direction at 0.3 mm/0.3% tolerance at each treatment site was 96.1% for the prostate, 93.5% for the lumbar spine, and 94.4% for the femur. Additionally, the average gamma pass rate results for the pelvic phantom in the X, Y, Z directions for a 10 mm shift were 96.2%, 96.3%, and 95.9%, respectively. DA is a powerful tool with high detection sensitivity and ability to detect body movement during treatment.

关键词： Delivery Analysis (DA) Tomotherapy Sinogram Intra-Fraction Motion Quality Assurance (QA)

IMPROVEMENT ON DEOXIDATION EFFICIENCY OF MOLTEN IRON WITH MAGNESIUM VAPOR PRODUCED IN-SITU BY ALUMINOTHERMIC REDUCTION OF MAGNESIA

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IMPROVEMENT ON DEOXIDATION EFFICIENCY OF MOLTEN IRON WITH MA...

Corrosion Behavior of a Titanium Alloy in Hot Nitric Acid Condensate

International Symposium on Global Environment and Steel Industry(ISES’03)

作者： Jiayi SHAN Takashi ITOH kuniyuki kITAGAWA Masamichi sano Research Center for Advanced Energy Conversion Nagoya University Japan Research Center for Advanced Energy Conversion Nagoya University Japan Research Center for Advanced Energy Conversion Nagoya University Japan Professor Emeritus of Nagoya University Japan

＜正＞A novel method of the deoxidation of the molten iron has been proposed with in-situ production of the magnesium vapor by aluminothermic reduction of magnesia. A reaction model has been developed to examine the rate controlling mechanism and highly efficient deoxidation with the magnesium vapor. The model calculation results show that, in order to achieve the high efficiency, control of the magnesium vapor pressure in the injected bubble is essential.

关键词： deoxidation molten iron magnesium vapor aluminothermic reduction clean steel.

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Journal of Energy and Power Engineering 2013年第6期7卷 1090-1096页

作者： Masayuki Takeuchi Yuichi sano Yasuo Nakajima Gunzo Uchiyama Yasuo Nojima Sachio Fujine Japan Atomic Energy Agency Tokai-mura Ibarakt" 3191194 Japan Japan Nuclear Energy Safety Organization Minato-ku Tokyo 1050001 Japan

The corrosion behavior of a titanium-5% tantalum alloy （Ti-STa） in hot nitric acid condensate was investigated to understand aging behavior ofreprocessing equipments. On the basis of long-term immersion tests, it was determined that the corrosion of Ti-STa in nitric acid condensate is accelerated with an increase in the concentration. The corrosion rate was nearly constant during the immersion test and the coupons suffered from uniform corrosion. In addition, it is important to note that the nitric acid concentration in the condensate increased on addition of metal salts to the heated nitric acid solution. The larger valence of metal ions was contributed to the increase in the concentration of nitric acid condensate. Consequently, the metal salt in the heated nitric acid solution accelerates the corrosion of Ti-STa in the condensate. Therefore, the nitric acid condensate condition should be carefully considered for the corrosion environment of titanium and its alloys.

关键词： Titanium-5% tantalum alloy corrosion spent nuclear fuel reprocessing nitric acid condensate metal salt effect Gibbsfree energy of hydration.

Novel ACLV1 Mutation Identified in Late Onset Hereditary Hemorrhagic Telangiectasia

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International Journal of Otolaryngology and Head & Neck Surgery 2016年第4期5卷 157-173页

作者： Cory Patrick kaitlin McIntyre Jeremy Ramidial sano Joa Vijaykumar Dinsukhlal Zaveri Damien Hansra Miller School of Medicine University of Miami Miami FL USA Jackson Memorial Hospital Miami FL USA Mercy Hospital Miami FL USA Oncology and Radiation Associates Miami FL USA

Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant disorder with variable expressivity. We present a 62-year-old patient with a rare, late-onset disease course featuring a novel mutation in ACVRL1, a... 详细信息

关键词： Hereditary Hemorrhagic Telaniectasia Osler-Weber-Rendu Syndrome Anemia Mutation

中国锦紫苏类病毒的检测及其分子生物学特征研究

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植物病理学报 2006年第3期36卷 226-231页

作者：苏前富郭瑞成卓敏 sano TERUO 李世访中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室 Laboratory of Phytopathology Faculty of Agriculture and Life Science Hirosaki University Hirosaki036 Japan

从无明显症状表现的11株锦紫苏叶片中抽提低分子量的RNA，经Return-PAGE、RT-PCR和Dot-blot hybridization检测，结果表明11株锦紫苏全部带有锦紫苏类病毒（Coleus blumei viroid，CBVd）。将部分PCR产物克隆到pGEM-3Zf（＋）载体上并进... 详细信息

从无明显症状表现的11株锦紫苏叶片中抽提低分子量的RNA，经Return-PAGE、RT-PCR和Dot-blot hybridization检测，结果表明11株锦紫苏全部带有锦紫苏类病毒（Coleus blumei viroid，CBVd）。将部分PCR产物克隆到pGEM-3Zf（＋）载体上并进行DNA序列测定。序列分析结果，所克隆的序列（GenBank登录号分别为DQ178395、DQ178396、DQ178397、DQ178398和DQ178399）与GenBank中报道的锦紫苏类病毒1号（CBVd—1）序列同源性为85．23％～99．20％。从市场上购买的锦紫苏种子经Return—PAGE和RT-PCR检测不携带锦紫苏类病毒。这是中国发生的锦紫苏类病毒的首次报道。

关键词：锦紫苏类病毒正反向电泳斑点杂交 RT-PCR

利用常间回文重复序列丛集介导的基因编辑评估Tet2和甲基转移酶3a在克隆性造血和心血管病中的作用

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中华高血压杂志 2018年第7期26卷 699-699页

作者： sano S Ohshima k Wang Y katanasaka Y sano M Walsh k 刘青叶鹏

克隆性血细胞生成与死亡率、心血管病发生率增加有关。这种情况可能是由于造血干/祖细胞（hematopoietic stem/progenitor cells,HSPC）内的前白血病驱动基因的体细胞突变引起的。大约有40个候选驱动基因已被确定出来,但有研究证明在这... 详细信息

克隆性血细胞生成与死亡率、心血管病发生率增加有关。这种情况可能是由于造血干/祖细胞（hematopoietic stem/progenitor cells,HSPC）内的前白血病驱动基因的体细胞突变引起的。大约有40个候选驱动基因已被确定出来,但有研究证明在这些基因中,仅一个基因[10-11易位-2（TET2）]的突变在大鼠模型中可导致心血管病。

关键词：克隆性造血心血管病甲基转移酶基因重复序列造血干/祖细胞体细胞突变评估

Safety trial of high-intensity focused ultrasound therapy for pancreatic cancer

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World Journal of Gastroenterology 2014年第28期20卷 9570-9577页

作者： Atsushi Sofuni Fuminori Moriyasu Takatomo sano Fumihide Itokawa Takayoshi Tsuchiya Toshio kurihara kentaro Ishii Syujiro Tsuji Nobuhito Ikeuchi Reina Tanaka Junko Umeda Ryosuke Tonozuka Mitsuyoshi Honjo Shuntaro Mukai Mitsuru Fujita Takao Itoi Department of Gastroenterology and Hepatology Tokyo Medical University

AIM:To evaluate the safety and clinical application of high-intensity focused ultrasound(HIFU)therapy for unresectable pancreatic cancer(PC).METHODS:Thirty PC patients(16 cases in stage III and 14 cases in stage IV)with visualized pancreatic tumors were admitted for HIFU therapy as an optional local therapy in addition to systemic chemotherapy or *** consent was *** study began at the end of 2008 and was approved by the ethics committee of our hospital[Institutional Review Board(IRB):890].The HIFU device used was the FEP-BY02(Yuande Bio-Medical Engineering,Beijing,China).RESULTS:The mean tumor size after HIFU therapy changed to 30.9±1.7 mm from 31.7±1.7 mm at *** were no significant changes in tumor size,mean number of treatment sessions(2.7±0.1 mm),or mean total treatment time(2.4±0.1 h).The rate of symptom relief effect was 66.7%.The effectiveness of primary lesion treatment was as follows:complete response,0;partial response,4;stable disease,22;progressive disease,*** after HIFU therapy included 2 operations,24 chemotherapy treatments,and 4 best supportive care *** events occurred in 10%of cases,namely pseudocyst formation in 2 cases and mild pancreatitis development in ***,no severe adverse events occurred in this ***:We suggest that HIFU therapy is safe and has the potential to be a new method of combination therapy for PC.

关键词： High-intensity focused ultrasound Pancreatic cancer Safety trial Tumor ablation Ultrasonography

DIFFERENCES IN RESISTANCE OF SWEET POTATO AND SOME OTHER FIELD CROPS TO MELOIDOGYNE INCOGNITA RACES IN JAPAN

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DIFFERENCES IN RESISTANCE OF SWEET POTATO AND SOME OTHER FIE...

Efficient Production of L-Theanine Using Immobilized Recombinant <i>Escherichia coli</i>Cells Expressing a Modified γ-Glutamyltranspeptidase Gene from <i>Pseudomonas nitroreducens</i>

The ⅩⅤth International Plant Protection Congress

作者： Z.sano H.IWAHORI Y.TATEISHI National Agricultural Research Center for kyushu Okinawa Region Nishigoshi Kumamoto 861-1192 Japan National Agricultural Research Center for kyushu Okinawa Region Nishigoshi Kumamoto 861-1192 Japan National Agricultural Research Center for kyushu Okinawa Region Nishigoshi Kumamoto 861-1192 Japan

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Advances in Biological Chemistry 2020年第6期10卷 157-171页

作者： Putthapong Phumsombat Chiharu sano Hiroki Ikezoe Junji Hayashi Takafumi Itoh Takao Hibi Mamoru Wakayama Department of Biotechnology College of Life Sciences Ritsumeikan University Shiga Japan Graduate School of Technology Industrial and Social Sciences Tokushima University Tokushima Japan Department of Bioscience and Biotechnology Fukui Prefectural University Fukui Japan

L-Theanine (γ-glutamylethylamide) is a naturally occurring amino acid derivative known to have several beneficial physiological effects as a diet supplement, and to give an umami taste when used as a food additive. The compound is industrially produced by γ-glutamyltranspeptidase from Pseudomonas nitroreducens (PnGGT). Using recombinant PnGGT, we have shown previously that Trp385, Phe417, and Trp525 are key amino acid residues for recognition of acceptor substrates at the PnGGT active site. Here, we demonstrate that a recombinant W525D mutant of PnGGT produces L-theanine from ethylamine and L-glutamine more efficiently than wild-type PnGGT, attributable to an increased ratio of transfer activity to hydrolysis activity. An efficient production of L-theanine was achieved by immobilizing Escherichia coli cells expressing the W525D PnGGT mutant (E. coli-W525D) using 2% alginate as the supporting material. The highest L-theanine production using immobilized E. coli-W525D, representing a conversion rate of 90%, was achieved in optimal reaction conditions of pH 10, 40°C, and a substrate molar ratio of L-glutamine to ethylamine of 1:10. The immobilized E. co

关键词： L-Theanine γ-Glutamyltranspeptidase Pseudomonas nitroreducens Escherichia coli Immobilization