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Clinical outcomes in patients diagnosed with extra-nodal Hodgkin lymphoma: a 20-year retrospective analysis of the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) database

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Cancer Advances 2024年第13期7卷 1-6页

作者： Kingsley Nnawuba Anup Kumar Trikannad Ashwini Kumar Sruthi Vellanki Tochukwu Nzeako Samantha Robinson hanna Jensen Internal Medicine Residency Program University of Arkansas for Medical Sciences-Northwest Regional Campus1125 North College AvenueFayettevilleArkansas 72703USA Division of Hematology Oncology and Myeloma University of Arkansas for Medical Sciences449 Jack Stephens Drive UAMS Winthrop P.Rockefeller Cancer Institute Seventh Floor Little RockArkansas 72205USA Internal Medicine Department Christiana Care Hospital4755 Ogletown Stanton RdNewarkDelaware 19718USA School of Human Environmental Sciences University of ArkansasRoom 118Home Economics Building987 W Maple StFayetteville AR 72701USA Department of Surgery University of Arkansas for Medical SciencesNorthwest Regional Campus1125 North College AvenueFayettevilleArkansas 72703USA.

Background:Hodgkin lymphoma refers to a malignancy of the lymphatic ***-nodal Hodgkin lymphoma(ENHL)is a rare variant consisting of Hodgkin lymphoma occurring outside the lymphatic *** investigating the epidemiology associated with ENHL are ***:618 ENHL cases were analyzed using the National Cancer Institute’s Surveillance,Epidemiology,and End Results(SEER)database(2000–2020).Demographics including sex,race/ethnicity,rural-urban continuum,age group(categorized as adolescent and young adult(AYA)if between years of 15 and 39,and adult if over the age of 40),and living status(alive/deceased)were examined,with survival status as the main ***:This study included 335 males(54.2%)and 283 females(45.8%).Of this total,47.9%were in the AYA *** terms of ethnicity the distribution was 12.5%non-Hispanic Black,67.5%non-Hispanic White,5.2%non-Hispanic Asian/Pacific Islander,and 14.9%*** analyses evidenced significant differences in survival by age group with 91.6%in AYA vs.72.4%in adults(Parch as such,tends to affirm that these two factors–age and race are quite crucial in the prognosis as well as management of *** to adults,AYA patients had significantly lower odds of death,while non-Hispanic Black individuals exhibited reduced survival *** should be noted that 27.0%of patients underwent surgery with 10.2%receiving post-operative radiation which led to decrease in mortality ***,these results reiterate the nec

关键词： Hodgkin lymphoma extra nodal disease SEER cancer survival

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