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Ecological and behavioural risk factors of scrub typhus in central Vietnam:a case-control study

Infectious Diseases of Poverty 2021年第4期10卷 97-97页

作者： hanh thi duc tran Jan Hattendorf Hung Manh Do Thanh Tien Hoang Hang thi Hai Hoang Hoa Ngoc Lam Mai Kim Huynh Lan thi Hoang Vu Jakob Zinsstag Daniel Henry Paris Esther Schelling Department of Epidemiology and Public Health Swiss Tropical and Public Health InstituteBaselSwitzerland 不详

Background The risk factors for scrub typhus in Vietnam remain *** typhus caused by Orientia tsutsugamushi often presents as an undifferentiated febrile illness and remains under appreciated due to the limited availability of diagnostic *** tropical rickettsial illness is increasingly recognized as an important cause of non-malaria acute undifferentiated fever in *** study aimed to investigate behavioural and ecological related risk factors of scrub typhus to prevent this potentially life-threatening disease in *** We conducted a clinical hospital-based active surveillance study,and a retrospective residence-enrolment date-age-matched case–control study in Khanh Hoa province,Vietnam,from August 2018 to March *** examinations,polymerase chain reaction and enzyme-linked immunosorbent assay IgM tests were applied to define cases and *** enrolled participants filled out a questionnaire including demographic socio-economic status,personal behaviors/protective equipment,habitat connections,land use,and possible exposure to the *** conditional logistic regression was used to define the scrub typhus associated risk *** We identified 44 confirmed cases and matched them with 152 *** cases and controls,the largest age group was the 41–50 years old and males accounted for 61.4%and 42.8%,*** were similarities in demographic characteristics between the two groups,with the exception of *** factors were significantly associated with acquisition of scrub typhus,including sitting/laying directly on household floor[adjusted OR(aOR)=4.9,95%CI:1.6–15.1,P=0.006],household with poor sanitation/conditions(aOR=7.9,95%CI:1.9–32.9,P=0.005),workplace environment with risk(aOR=3.0,95%CI:1.2–7.6,P=0.020),always observing mice around home(aOR=3.7,95%CI:1.4–9.9,P=0.008),and use of personal protective equipment in the field(aOR=0.4,95%CI:0.1–1.1,P=0.076).Conclusions Ecological

关键词： Ecological Environmental Behaviour Risk factor Scrub typhus Orientia tsutsugamushi Vietnam

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Population-based X-ray gastric cancer screening in Hiroshima prefecture, Japan

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World Journal of Clinical Oncology 2024年第2期15卷 271-281页

作者： Nhu thi hanh Vu Yuji Urabe duc Trong Quach Shiro Oka Toru Hiyama Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastrointestinal Endoscopy and Medicine Hiroshima University HospitalHiroshima 734-8551Japan Department of Gastroenterology Hiroshima University HospitalHiroshima 734-8551Japan Health Service Center Hiroshima UniversityHigashihiroshima 739-8514Japan

BACKGROUND X-ray gastric cancer(GC)screening has been shown to decrease ***-based X-ray GC screening has been performed in Hiroshima Prefe-cture,Japan,since 1983 but time trends and the efficacy of the method over 39 years have not been *** this was a population-based retrospective *** data were derived from aggregated data of the Hiroshima Regional Health Medical Promotion Organization,including the number and rate of participants and those requiring esophagogastroduodenoscopies(EGDs),the number and rate of participants diagnosed as having GC,and the positive predictive value of the abnormal findings detected by X-ray and confirmed by *** number and rate of esophageal cancers were also ***,the cost of detecting one GC was *** The number of participants has decreased during the last four decades,from 39925 in 1983 to 12923 in *** rate of those requiring EGDs decreased significantly in recent years(P<0.001).The number of participants diagnosed as having GC has also declined,from 76 to 10 ***,the rate of cases diagnosed as GC among the participants remained around 0.1%.The positive predictive value increased significantly in recent years except during *** number and rate of accidentally detected esophageal cancers have risen recently,from 0%in 2008 to 0.02%in 2021,one-fifth of the diagnosis rate of *** GC diagnosis costs approximately 4200000 Japanese Yen(30000 United States Dollars)for the X-ray screenings and *** X-ray GC screening in Hiroshima has been efficient,but one challenge is the *** cancers may also need to be considered because they have gradually increased in recent years.

关键词： Population Retrospective studies X-ray Gastric cancer Screening

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Prevalence, risk factors, and BRAF mutation of colorectal sessile serrated lesions among Vietnamese patients

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World Journal of Clinical Oncology 2024年第2期15卷 290-301页

作者： Nhu thi hanh Vu Huy Minh Le Diem thi-Ngoc Vo Hoang Anh Vu Nhan Quang Le Dung Dang Quy Ho duc Trong Quach Department of Internal Medicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam GI Endoscopy Department University Medical Center at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Histology-Embryology and Pathology University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Center for Molecular Biomedicine University of Medicine and Pharmacy at Ho Chi Minh CityHo Chi Minh 700000Viet Nam Department of Endoscopy Cho Ray HospitalHo Chi Minh 700000Viet Nam

BACKGROUND Sessile serrated lesions(SSLs)are considered precancerous colorectal lesions that should be detected and removed to prevent colorectal *** studies in Vietnam mainly investigated the adenoma pathway,with limited data on the serrated *** To evaluate the prevalence,risk factors,and BRAF mutations of SSLs in the Vietnamese *** this is a cross-sectional study conducted on patients with lower gastrointestinal symptoms who underwent colonoscopy at a tertiary hospital in *** were diagnosed on histopathology according to the 2019 World Health Organi-zation *** mutation analysis was performed using the Sanger DNA sequencing *** multivariate logistic regression model was used to determine SSL-associated *** There were 2489 patients,with a mean age of 52.1±13.1 and a female-to-male ratio of 1:*** prevalence of SSLs was 4.2%[95%confidence interval(CI):3.5-5.1].In the multivariate analysis,factors significantly associated with SSLs were age≥40[odds ratio(OR):3.303;95%CI:1.607-6.790],male sex(OR:2.032;95%CI:1.204-3.429),diabetes mellitus(OR:2.721;95%CI:1.551-4.772),and hypertension(OR:1.650,95%CI:1.045-2.605).The rate of BRAF mutations in SSLs was 35.5%.CONCLUSION The prevalence of SSLs was 4.2%.BRAF mutations were present in one-third of *** risk factors for SSLs included age≥40,male sex,diabetes mellitus,and hypertension.

关键词： Colorectal cancer Sessile serrated lesion BRAF mutation Risk factors Diabetes mellitus Hypertension

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Morphological Change in the Northern Red River Delta,Vietnam

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Journal of Ocean University of China 2018年第6期17卷 1272-1280页

作者： BUI Vuong Van FAN Daidu NGUYEN Dac Ve tran Dinh Lan tran duc Thanh HOANG Van Long NGUYEN thi Hong hanh Institute of Marine Environment and Resources Vietnam Academy of Science and TechnologyHaiphong 18000Vietnam State Key Laboratory of Marine Geology Tongji UniversityShanghai 200092China Hanoi University of Mining and Geology Hanoi 10000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi 10000Vietnam

Coastal erosion has become a worldwide concern, typically in the densely populated Asian mega-river deltas. Severe coastal erosion in the southern Red River Delta(RRD) has been intensively studied. Coastal morphological change in the northern RRD was examined in detail through DEM(Digital Elevation Model) analysis based on time series of bathymetrical maps(1965–2004) and Landsat images(1975–2015) in this study. The results show that the northern RRD is featured by rapid coastal accretion in the past few decades, although suspended sediment flux has dropped by roughly 60% after the completeness of Hoa Binh Dam(HBD) in 1988 and relative sea level rose at 1.9 mm yr^(-1). However, accretion at the outer part of subtidal shoals and platforms was observed to slow down quickly or even turned into erosion in the last two decades. The resuspended sediments from the erosion zone can be transported landward to replenish the inner coastal zone, keeping the latter accretion in the near future to compensate for the sediment discharge decrease from the river. However, this lag effect should be terminated soon if other adverse effects go worse, e.g., damming rivers, sea-level rising, strengthening storms, land reclamation and other poor-designed coastal engineering. Coastal planners and managers should pay full attention to these changes.

关键词： Morphological change DEM coastal erosion coastal engineering coastal management tide-dominated Red River Delta

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Treatment for COVID-19 patients in Vietnam: Analysis of time-to-recovery

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Asian Pacific Journal of Tropical Medicine 2020年第9期13卷 397-401页

作者： Khuong Quynh Long Hoang Hong hanh tran thi Tuyet hanh La Ngoc Quang Hoang Van Minh Hanoi University of Public Health 1A Duc Thang RoadDuc Thang WardNorth Tu Liem DistrictHanoiVietnam

Objective:To describe the recovery time and related factors among COVID-19 patients in ***:We used the secondary data obtained from the official database of the Ministry of Health of Vietnam and other public data sources that were available by April 9 th,*** proportional hazards model was carried out to identify factors related to recovery time among COVID-19 ***:By April 9 th,2020,the cumulative number of COVID-19 cases detected in Vietnam was 255,of which 129(50.6%)patients had fully *** median recovery time of patients was 17(95%CI=16-19)*** patients had a lower likelihood of recovery(HR=0.98,95%CI=0.97-0.99,P<0.001),whereas patients with a history of international incoming travel had a higher likelihood of recovery(HR=1.57,95%CI=1.03-2.40,P=0.036).There was no statistically significant difference in the recovery time of patients treated in different hospital ***:More attention is needed for older patients and who did not have international travel *** confirmed with COVID-19 could be treated at local health facilities to avoid unnecessary referrals and burdens to specialized hospitals at the central level.

关键词： COVID-19 Coronavirus Recovery Vietnam

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A study implementing real-time PCR to identify Strongyloides species of third-stage larvae in human stool samples from Southern Vietnam

Infectious Medicine

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Infectious Medicine 2023年第3期2卷 229-236页

作者： Le duc Vinh Nguyen Kim Thach Huynh Hong Quang Do Nhu Binh tran thi duc hanh Nguyen Minh Toàn Nguyen Trung Tuyen Nguyen Thu Huong Department of Medical Parasitology Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Department of Fundamental Chemistry-Biochemistry Pham Ngoc Thach University of MedicineHo Chi Minh City 700000Vietnam Clinical Epidemiology Research Unit Institute of MalariologyParasitologyand Entomology Quy NhonBinh Dinh 55000Vietnam Department of Infectious Disease Military Hospital 103Hanoi 100000Vietnam Department of Epidemiology Hanoi University of Public HealthHanoi 100000Vietnam Department of Microbiology-Parasitology Hanoi University of Public HealthHanoi 100000Vietnam Department of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi100000 Vietnam

Background:Strongyloidiasis,a neglected disease caused by intestinal nematodes of the genus,is endemic to tropical and subtropical areas such as *** methods only identify the genus,while DNA-molecular techniques are susceptible in Strongyloides *** study aims to determine the prevalence of dominant Strongyloides species among the population in duc Hoa district,Long An,***:A cross-sectional study used 1190 stool specimens collected from July 2017 to November *** samples were transported within 2 h,stored at 2-8℃,and processed within 48 h for microscopy smear and culture at the Laboratory of Medical Parasitology,Pham Ngoc Thach University of Medicine(PNT).Then all positive samples with the above 2 methods were verified by real-time PCR ***-time PCR amplification was conducted at the Laboratory of Molecular Biology,***:Direct microscopy and modified Harada-Mori culture detected Strongyloides *** in 79/1190 sam-ples(6.6%).About 94.2%of the DNA samples were Strongyloides stercoralis,2.9%were co-infections with Strongy-loides ratti and ***,and 2.9%were patients with *** identity of 12/14 sequences was confirmed as *** with a high level of similarity(91.3%-100%)and over 98%for ***:DNA-molecular techniques and sequence analysis are highly suitable for identifying Strongyloides species isolated from stool *** is remarkable evidence of the presence of zoonosis *** disease in human,not just the known *** is likely to result in a certain proportion of people being infected by this animal-borne infectious pathogen.

关键词： Strongyloidiasis Strongyloides stercoralis Strongyloides ratti DNA-molecular techniques

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Effects of Silicon-Based Fertilizer on Growth, Yield and Nutrient Uptake of Rice in Tropical Zone of Vietnam

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Rice science 2017年第5期24卷 283-290页

作者： tran Xuan CUONG Hayat ULLAH Avishek DATTA tran Cong hanh Department of Food Agriculture and Bioresources School of Environment Resources and Development Asian Institute of Technology Pathum Thani 12120 Thailand Department of Soil Science Faculty of Agriculture Forestry and Fishery Hong Duc University Dong Ve Thanh Hoa 440000 Vietnam

Application of silicon(Si) could greatly boost rice yield and mitigate abiotic stress,especially drought.A field experiment was conducted during 2015 at the research farm of Hong duc University,Thanh Hoa City,Vietnam,to evaluate the effects of five different combined doses of standard fertilizer practice and Si fertilizer on growth,yield and yield components,as well as nutrient uptake of *** treatments consisted of the recommended dose of fertilizer(RDF,110 kg/hm^2 N + 90 kg/hm^2 P_2O_5 + 80 kg/hm^2 K_2O) as the control,RDF + 100 kg/hm^2 SiO_2,RDF + 200 kg/hm^2 SiO_2,RDF + 300 kg/hm^2 SiO_2 and RDF + 400 kg/hm^2 SiO_*** results showed that the growth,grain and straw yields as well as yield components(number of grains per panicle,seed-setting rate and 1000-grain weight) were significantly affected by Si *** highest grain yield of 3 705 kg/hm^2 was obtained with the highest level of Si fertilizer in combination with RDF(RDF + 400 kg/hm^2 SiO_2),however,it was statistically at par with the yields obtained with RDF + 300 kg/hm^2 SiO_2(3 664 kg/hm^2) and RDF + 200 kg/hm^2 SiO_2(3 621 kg/hm^2).The optimum dose of Si fertilizer with maximized grain yield(3 716 kg/hm^2) was 329 kg/hm^2 SiO_*** nutrient(Si,N,P and K) uptakes of rice were also significantly enhanced by Si *** application at the level of 329 kg/hm^2 along with RDF would help in the sustainable production of rice in the tropical zone of Vietnam.

关键词： silicon yield nutrient uptake standard fertilizer practice rice fertilizer

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Novel Time Series Bagging Based Hybrid Models for Predicting Historical Water Levels in the Mekong Delta Region, Vietnam

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Computer Modeling in Engineering & Sciences 2022年第6期131卷 1431-1449页

作者： Nguyen Thanh Hoan Nguyen Van Dung Ho Le Thu Hoa Thuy Quynh Nadhir Al-Ansari tran Van Phong Phan Trong Trinh Dam duc Nguyen Hiep Van Le hanh Bich thi Nguyen Mahdis Amiri Indra Prakash Binh Thai Pham Institute of Geography Vietnam Academy of Science and TechnologyHanoi10000Viet Nam Department of Civil Environmental and Natural Resources EngineeringLulea University of TechnologyLulea97187Sweden Institute of Geological Sciences Vietnam Academy of Science and Technology(VAST)Dong DaHanoi10000Viet Nam University of transport Technology Thanh XuanHa Noi10000Viet Nam Department of Watershed&Arid Zone Management Gorgan University of Agricultural Sciences&Natural ResourcesGorgan***Iran DDG(R)Geological Survey of India Gandhinagar382010India

Water level predictions in the river,lake and delta play an important role in flood *** year Mekong River delta of Vietnam is experiencing flood due to heavy monsoon rains and high *** subsidence may also aggravate flooding problems in this ***,accurate predictions of water levels in this region are very important to forewarn the people and authorities for taking timely adequate remedial measures to prevent losses of life and *** are so many methods available to predict the water levels based on historical data but nowadays Machine Learning(ML)methods are considered the best tool for accurate *** this study,we have used surface water level data of 18 water level measurement stations of the Mekong River delta from 2000 to 2018 to build novel time-series Bagging based hybrid ML models namely:Bagging(RF),Bagging(SOM)and Bagging(M5P)to predict historical water levels in the study *** of the Bagging-based hybrid models were compared with Reduced Error Pruning Trees(REPT),which is a benchmark ML *** data of 19 years period was divided into 70:30 ratio for the *** data of the period 1/2000 to 5/2013(which is about 70%of total data)was used for the training and for the period 5/2013 to 12/2018(which is about 30%of total data)was used for testing(validating)the *** of the models was evaluated using standard statistical measures:Coefficient of Determination(R2),Root Mean Square Error(RMSE)and Mean Absolute Error(MAE).Results show that the performance of all the developed models is good(R2>0.9)for the prediction of water levels in the study ***,the Bagging-based hybrid models are slightly better than another model such as ***,these Bagging-based hybrid time series models can be used for predicting water levels at Mekong data.

关键词： Computational techniques bagging water level time series algorithms

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不同含水状态级配碎石临界动应力及变形规律研究

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铁道学报 2016年第6期38卷 100-107页

作者：刘宝苏谦 PHAM duc Phong 白皓 LAM thi Huyen hanh 西南交通大学土木工程学院四川成都610031 Le Quy Don技术大学特种工程学院越南河内100803 四川高速公路建设开发总公司四川成都610041

为评估含水率变化对高速铁路无砟轨道基床表层级配碎石动力性能的影响,本文针对最优含水率和饱和含水率两种状态下级配碎石循环动力性能开展室内大型动三轴试验研究,分析级配碎石的临界动应力和累积变形特性。研究表明:累积变形与荷载... 详细信息

为评估含水率变化对高速铁路无砟轨道基床表层级配碎石动力性能的影响,本文针对最优含水率和饱和含水率两种状态下级配碎石循环动力性能开展室内大型动三轴试验研究,分析级配碎石的临界动应力和累积变形特性。研究表明:累积变形与荷载作用次数、含水率关系密切,荷载作用次数超过10 000次后,含水率的影响逐渐显现,荷载作用次数达到20 000次时,饱和含水率的累积变形相对最优含水率增大70%;不同含水率级配碎石的衰减型和破坏型累积变形曲线可分别用Stewart模型和Monismith模型预测;级配碎石临界动应力随含水率增大而减小,随围压的增大线性增大,饱和含水状态对应的临界动应力较最优含水状态平均小13%。

关键词：高速铁路级配碎石大型三轴试验不同含水率累积变形临界动应力

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Embryonic, genetic and clinical outcomes of fresh versus vitrified oocyte: A retrospective cohort study

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Asian pacific Journal of Reproduction 2023年第6期12卷 266-272页

作者： Phuong Dao thi Son Dang Truong Thuan Nguyen duc Anh Pham Van Anh Do Tuan Van hanh Nguyen HP Fertility-Hai Phong International Hospital of Obstetrics and Pediatrics Haiphong180000Vietnam Graduate University of Science and Technology Vietnam Academy of Science and TechnologyHanoi100000Vietnam Institute of Biotechnology Vietnam Academy of Science and TechnologyHanoi100000Vietnam

Objective:To compare embryonic development,ploidy status and clinical outcomes between fresh and frozen-thawed ***:this retrospective cohort study evaluated 83 fertilization cycles including both fresh and frozen oocytes from 79 patients at the HP Fertility Center of Hai Phong International Hospital of Obstetrics and Pediatrics in *** patient underwent several ovarian stimulation cycles to accumulate a certain number of oocytes that would be *** the last oocyte retrieval,all patient’s oocytes including both frozen and fresh would be *** outcomes included the rates of oocyte survival,cleavage embryo,blastocyst,ploidy status,pregnancy,biochemical pregnancy and clinical ***:The oocyte survival rate after thawing was 96.5%.No statistically significant difference was found when comparing fresh and frozen oocytes regarding fertilization rate(78.1%vs.75.5%,P=0.461),usable cleavage embryo rate(86.9%vs.87.2%,P=0.916)but usable blastocyst rate was found higher statistically in the frozen oocyte group(44.4%vs.54.0%,P=0.049).The percentages of euploid,aneuploid and mosaic embryos between the fresh group and the vitrified group had no significant differences(33.8%vs.31.6%,P=0.682;51.0%vs.54.2%,P=0.569;15.2%vs.12.4%,P=0.787;respectively).The rates of pregnancy,biochemical pregnancy and clinical pregnancy had no statistical difference(68.8%vs.64.8%,P=0.764;12.5%vs.3.6%,P=0.258;37.5%vs.46.4%,P=0.565).17 Mature oocytes are the minimum to have at least one euploid ***:Oocyte vitrification does not affect embryonic,genetic and clinical *** number of mature oocytes should be considered for fertilization in some cases.

关键词： Clinical outcomes Embryonic development Genetic outcomes Human oocyte Oocyte accumulation Oocyte cryopreservation Ploidy status Vitrified oocyte

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