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A brief analysis of the classical poetry Chinese-English translation： From the perspective of ＂Beauty in three aspects＂

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Sino-US English Teaching 2010年第2期7卷 52-58页

作者： zeng hang-li College of Foreign Languages Zhejiang Normal University Jinhua 321004 China

With the growing of mutual communication between different cultures, the translation of classical Chinese poetry becomes quite significant in the contemporary times. This paper first briefly introduces classical Chinese poetry, major classical Chinese poetry translation schools and their representatives, and professor XU Yuan-zhong＇s famous principle of ＂Beauty in three aspects＂. In order to help disseminate this part of Chinese culture through discussing how the reader of the translation may be inspired, moved and aesthetically entertained in the same way as one reads the original, this paper will analyze the classical poetry Chinese-English translation from the perspective of ＂Beauty in three aspects＂, namely, in three parts--beauty in meaning, beauty in sound and beauty in form. Thus, it serves the purpose to offer a relatively comprehensive view of the classical poetry Chinese-English translation.

关键词： classical Chinese poetry "Beauty in three aspects" Chinese-English translation

Predicting Bioaccumulation of Nanomaterials:Modeling Approaches with Challenges

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Environment & Health 2024年第4期2卷 189-201页

作者： hang zeng Zhuoyan Lv Xiaoyan Sun Yang Tong Wei Wu Shipeng Dong Liang Mao State Key Laboratory of Pollution Control and Resource Reuse School of the EnvironmentChemistry and Biomedicine Innovation CenterNanjing UniversityNanjing 210023China Nanjing Qixia District Hospital Nanjing 210023China High Tech Research and Development Center Ministry of Science and TechnologyBeijing 100044China

Understanding the bioaccumulation of nanomaterials(NMs)by organisms is essential in evaluating their potential ***,the experimental determination of bioaccumulation is substantially challenging,which spawned the development of prediction approaches via establishing models for various *** modeling approaches,such as the biotic ligand model(BLM),partition coefficients,accumulation factor models,and quantitative structure−activity relationship(QSAR)models,were initially used in the application of NMs,aiming to provide a reliable quantitative dose in a resource-saving *** methods,which are based on the uptake patterns of substances,probably lead to deviated results due to the different uptake behaviors of *** this study,currently developed models to evaluate the bioaccumulation of NMs are critically reviewed,with their feasibilities and limitations being *** addition,the recently developed machine learning amended models have taken great efforts in realizing biological behaviors of NMs in organisms by providing in silico *** this data-driven approach has limitations in mechanism exploration,it may give different insights into the bioaccumulation model establishment and critical feature identification.

关键词： Modeling Forecast Bioaccumulation Nanomaterials Machine learning

LB100 ameliorates nonalcoholic fatty liver disease via the AMPK/Sirt1 pathway

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World Journal of Gastroenterology 2019年第45期25卷 6607-6618页

作者： Xue-Yang Chen Chang-Zhou Cai Meng-Li Yu Ze-Min Feng Yu-Wei Zhang Pei-Hao Liu hang zeng Chao-Hui Yu Department of Gastroenterology The First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Clinical Research Center for Hepatobiliary and Pancreatic Diseases of Zhejiang Province Hangzhou 310003Zhejiang ProvinceChina

BACKGROUND It is well known that nonalcoholic fatty liver disease(NAFLD)is associated with insulin resistance(IR).LB100,a serine/threonine protein phosphatase 2A(PP2A)inhibitor,is closely related to ***,there is little data regarding its direct influence on *** To elucidate the effect and underlying mechanism of LB100 in *** After 10 wk of high fat diet(HFD)feeding,male C57BL/6 mice were injected intraperitoneally with vehicle or LB100 for an additional 6 wk(three times a week).The L02 cell line was treated with LB100 and free fatty acids(FFAs)for 24 *** and eosin and oil red O staining were performed for histological *** blot analysis was used to detect the protein expression of Sirtuin 1(Sirt1),total and phosphorylated AMP-activated protein kinaseα(AMPKα),and the proteins involved in lipogenesis and fatty acid *** mRNA levels were determined by *** inhibition of AMPK was performed to further examine the exact mechanism of LB100 in *** LB100 significantly ameliorated HFD-induced obesity,hepatic lipid accumulation and hepatic injury in *** addition,LB100 significantly downregulated the protein levels of acetyl-CoA carboxylase,sterol regulatory element-binding protein 1 and its lipogenesis target genes,including stearoyl-CoA desaturase-1 and fatty acid synthase,and upregulated the levels of proteins involved in fatty acidβ-oxidation,such as peroxisome proliferator-activated receptorα(PPARα),peroxisome proliferator-activated receptor gamma coactivator-1α(PGC-1α),carnitine palmitoyltransferase 1α,acyl-CoA oxidase 1 and uncoupling protein 2,as well as the upstream mediators Sirt1 and AMPKαin the livers of HFD-fed *** vitro,LB100 alleviated FFA-induced lipid accumulation in L02 cells through the AMPK/Sirt1 signaling *** studies showed that the curative effect of LB100 on lipid accumulation was abolished by inhibiting AMPKαin L02 *** PP2A inhibition by LB

关键词： LB100 Nonalcoholic fatty liver disease Serine/threonine-protein phosphatase 2A Lipid metabolism AMP-activated protein kinaseα Sirtuin 1

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混合分布在非一致性洪水频率分析的应用

天津大学学报 2013年第4期46卷 298-303页

作者：冯平曾杭李新天津大学水利工程仿真与安全国家重点实验室天津300072

大清河流域由于兴建防洪工程,改变了原天然河道的洪水径流关系,使得用于大型水库防洪调度的入库洪水序列失去了一致性.本文以龙门水库的年洪峰序列、固定时段的年最大洪量序列(1日、3日和6日)为例,首先对此4个洪水序列采用水文变异诊断... 详细信息

大清河流域由于兴建防洪工程,改变了原天然河道的洪水径流关系,使得用于大型水库防洪调度的入库洪水序列失去了一致性.本文以龙门水库的年洪峰序列、固定时段的年最大洪量序列(1日、3日和6日)为例,首先对此4个洪水序列采用水文变异诊断系统进行变异分析,识别非一致性洪水序列的变异点.并在2个分布组成的混合分布假设下,研究非一致性洪水序列的频率计算问题,用模拟退火算法对混合分布进行参数估计,并将混合分布给出的设计洪水与不考虑变异情况的设计洪水以及1985年水利部规划总院(WRHPDGI)审定的设计洪水进行了比较分析.结果表明,相比不考虑变异情况的设计洪水值,考虑变异情况下的不同设计标准的设计洪水值均有不同程度的减小,且变异的程度均较明显,说明大清河流域下垫面和人类活动的变化导致入库洪水减少的现象较明显,进行设计洪水的校核和修订很有必要.

关键词：非一致性混合分布频率计算设计洪水

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洪水序列变异条件下的频率分析与计算

水力发电学报 2014年第6期33卷 11-19,45页

作者：李新曾杭冯平天津大学水利工程仿真与安全国家重点实验室天津300072

海河流域由于兴建大量防洪和水保工程,改变了流域下垫面条件,导致天然洪水产汇流特性发生变化,洪水系列不再满足一致性假定,进行设计洪水的修订势在必行。以海河大清河水系南支沙河上游的王快水库入库年洪峰序列和年最大洪量序列为例,... 详细信息

海河流域由于兴建大量防洪和水保工程,改变了流域下垫面条件,导致天然洪水产汇流特性发生变化,洪水系列不再满足一致性假定,进行设计洪水的修订势在必行。以海河大清河水系南支沙河上游的王快水库入库年洪峰序列和年最大洪量序列为例,基于各序列变异点诊断结果,应用混合分布法和条件概率分布法,直接对非一致性洪水序列进行频率分析,得到基于变异序列的设计洪水成果。并将两种方法得到的设计洪水成果分别与1985年水利部规划总院（WRHPDGI）审定的王快水库设计洪水成果及不考虑变异条件下的P-Ⅲ曲线拟合设计洪水成果进行对比,结果表明,考虑变异条件下的不同标准的设计洪水值均较1985年设计洪水值有所减小,年洪峰减小幅度为15%～30%,年最大时段洪量减小幅度为5%～30%;较不考虑变异条件下的P-Ⅲ曲线拟合设计洪水成果也有一定程度的减小,年洪峰、年最大1日洪量、年最大6日洪量减小幅度小于10%,年最大3日洪量减小幅度为1%～15%。该结论可为大清河流域设计洪水的修订提供一定的理论依据。

关键词：水文学洪水频率分析混合分布条件概率分布

Delivery of an Rhs-family nuclease effector reveals direct penetration of the gram-positive cell envelope by a type VI secretion system in Acidovorax citrulli

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mLife 2022年第1期1卷 66-78页

作者： Tong-Tong Pei Yumin Kan zeng-hang Wang Ming-Xuan Tang Hao Li Shuangquan Yan Yang Cui Hao-Yu Zheng Han Luo Xiaoye Liang Tao Dong State Key Laboratory of Microbial Metabolism Joint International Research Laboratory of Metabolic&Developmental SciencesSchool of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityShanghaiChina Department of Immunology and Microbiology School of Life SciencesSouthern University of Science and TechnologyGuangdongChina

The type VI secretion system(T6SS)is a double-tubular nanomachine widely found in gram-negative *** spear-like Hcp tube is capable of penetrating a neighboring cell for cytosol-to-cytosol protein ***,gram-positive bacteria have been considered impenetrable to such T6SS *** we report that the T6SS of a plant pathogen,Acidovorax citrulli(AC),could deliver an Rhsfamily nuclease effector RhsB to kill not only gram-negative but also gram-positive *** bioinformatic,biochemical,and genetic assays,we systematically identified T6SS-secreted effectors and determined that RhsB is a crucial antibacterial *** contains an N-terminal PAAR domain,a middle Rhs domain,and an unknown C-terminal *** is subject to self-cleavage at both its N-and C-terminal domains and its secretion requires the upstream-encoded chaperone EagT2 and *** toxic Cterminus of RhsB exhibits DNase activities and such toxicity is neutralized by either of the two downstream immunity proteins,RimB1 and *** of rhsB significantly impairs the ability of killing Bacillus subtilis while ectopic expression of immunity proteins RimB1 or RimB2 confers *** demonstrate that the AC T6SS not only can effectively outcompete Escherichia coli and *** in planta but also is highly potent in killing other bacterial and fungal ***,these findings highlight the greatly expanded capabilities of T6SS in modulating microbiome compositions in complex environments.

关键词： cell envelope cell wall interspecies interaction protein secretion

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氧化石墨烯的制备及其负载纳滤膜性能

华东理工大学学报（自然科学版） 2018年第5期44卷 644-649页

作者：曾行杨座国华东理工大学化工学院上海200237

纳滤膜在污水处理和海水淡化等方面具有独特的优势,因而一直是膜研究领域的热点。氧化石墨烯(GO)因自身特殊的分子层结构及表面电荷性质,可应用于复合纳滤膜的制备中。采用改进Hummers法制备得到氧化程度较高的GO,再通过压力辅助自组装... 详细信息

纳滤膜在污水处理和海水淡化等方面具有独特的优势,因而一直是膜研究领域的热点。氧化石墨烯(GO)因自身特殊的分子层结构及表面电荷性质,可应用于复合纳滤膜的制备中。采用改进Hummers法制备得到氧化程度较高的GO,再通过压力辅助自组装法制得氧化石墨烯-聚偏氟乙烯(GO-PVDF)复合纳滤膜。通过对NaCl和Na_2SO_4进行脱除测试,研究负载量、盐溶液质量浓度等因素对GO-PVDF复合纳滤膜截留率和渗透通量的影响。实验结果表明,增大GO负载量有助于获得较好的脱盐效果。在相同条件下,GO-PVDF复合纳滤膜对Na_2SO_4的截留率高于对NaCl的截留率,且对低浓度盐溶液的脱除率更高。纳滤膜长周期稳定性测试表明,GO-PVDF复合纳滤膜的渗透通量和截留率基本保持稳定,经过12h后其对NaCl和Na_2SO_4的截留率分别可达58.9%和76.6%。

关键词：氧化石墨烯纳滤膜压力辅助自组装脱盐

Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways

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World Journal of Gastroenterology 2019年第34期25卷 5120-5133页

作者： Chun-Xiao Li Jian-Guo Gao Xing-Yong Wan Yi Chen Cheng-Fu Xu Ze-Min Feng hang zeng Yi-Ming Lin Han Ma Ping Xu Chao-Hui Yu You-Ming Li Department of Gastroenterology the First Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310003Zhejiang ProvinceChina Clinical Research Center for Hepatobiliary and Pancreatic Diseases of Zhejiang Province Hangzhou 310003Zhejiang ProvinceChina

BACKGROUND Allyl isothiocyanate(AITC),a classic anti-inflammatory and antitumorigenic agent,was recently identified as a potential treatment for obesity and insulin ***,little is known about its direct impact on the *** To investigate the effect and underlying mechanism of AITC in nonalcoholic fatty liver disease(commonly referred to as NAFLD).METHODS To establish a mouse and cellular model of NAFLD,C57BL/6 mice were fed a high fat diet(HFD)for 8 wk,and AML-12 cells were treated with 200μM palmitate acid for 24 *** AITC treatment,mice were administered AITC(100 mg/kg/d)orally and AML-12 cells were treated with AITC(20μmol/L).RESULTS AITC significantly ameliorated HFD-induced weight gain,hepatic lipid accumulation and inflammation in ***,serum alanine aminotransferase and aspartate aminotransferase levels were markedly reduced in AITC-treated ***,AITC significantly downregulated the protein levels of sterol regulatory elementbinding protein 1(SREBP1)and its lipogenesis target genes and upregulated the levels of proteins involved in fatty acidβ-oxidation,as well as the upstream mediators Sirtuin 1(Sirt1)and AMPactivated protein kinaseα(AMPKα),in the livers of HFD-fed *** also attenuated the nuclear factor kappa B(NF-κB)signaling ***,AITC relieved palmitate acid-induced lipid accumulation and inflammation in AML-12 cells in vitro through the Sirt1/AMPK and NF-κB signaling ***,further studies showed that the curative effect of AITC on lipid accumulation was abolished by siRNA-mediated knockdown of either Sirt1 or AMPKαin AML-12 *** AITC significantly ameliorates hepatic steatosis and inflammation by activating the Sirt1/AMPK pathway and inhibiting the NF-κB ***,AITC is a potential therapeutic agent for NAFLD.

关键词： Allyl isothiocyanate Nonalcoholic fatty liver disease Hepatic steatosis Liver inflammation

运动式治理的反弹逻辑:以武汉市全国文明城市建设为例

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中南财经政法大学研究生学报 2018年第A1期 27-33页

作者：曾航中南财经政法大学公共管理学院

尽管决策者往往在运动式治理过程中试图构建固化治理效果的长效机制，然而运动式治理依然以治理效果的反弹而告终。通过以武汉市今年创建全国文明城市的过程为案例，运用范米特和范霍恩的政策执行系统模型，揭示了运动式治理效果的反弹... 详细信息

尽管决策者往往在运动式治理过程中试图构建固化治理效果的长效机制，然而运动式治理依然以治理效果的反弹而告终。通过以武汉市今年创建全国文明城市的过程为案例，运用范米特和范霍恩的政策执行系统模型，揭示了运动式治理效果的反弹是由治理过程中的多种矛盾导致的：一是长期目标与短期标准的矛盾；二是规范和激励之间的矛盾；三是管理机构的临时性与治理目标的长期性之间的矛盾；四是反复开展的运动式治理和社会环境之间的矛盾。

关键词：运动式治理政策执行文明城市