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Temperature distribution and dynamic control of secondary cooling in slab continuous casting

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International Journal of Minerals,Metallurgy and Materials 2009年第6期16卷 626-631页

作者： liang-hang Guo Yong Tian Man Yao Hou-fa Shen School of Materials Science and Engineering Dalian University of Technology Dalian 116023 China Anshan Iron and Steel Group Anshan 114021 China Department of Mechanical Engineering Tsinghua University Beijing 100084 China

To predict and optimize the temperature distribution of slab continuous casting in steady operational state, a three-dimensional model （named ＂offline model＂） based on the heat transfer and solidification theories was developed. Both heat transfer and flux distribution characteristics of the nozzle sprays on the slab were considered, and the complicated boundary conditions, such as spray cooling, natural convection, thermal radiation as well as contact cooling of individual rolls were involved in the model. By using the calibrated caster dependent model factors, the calculated temperature and shell thickness accorded well with the measured. Furthermore, a dynamic secondary water cooling control system was also developed on the basis of a two-dimensional transient heat transfer model （named ＂online model＂） and incremental PID control algorithm to reduce slab surface temperature fluctuation in unsteady state. Compared with the traditional spray table control method, the present online model and dynamic PID control demonstrate a higher capability and flexibility to adjust cooling water flowrate and reduce slab surface temperature fluctuation when the casting speed is changed.

关键词： mathematical model slab temperature dynamic control continuous casting

A medical image encryption algorithm based on synchronization of time-delay chaotic system

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Advances in Manufacturing 2017年第2期5卷 158-164页

作者： Hua Wang Jian-Min Ye hang-Feng liang Zhong-Hua Miao Shanghai Key Laboratory of Power Station Automation Technology School of Mechatronic Engineering and Automation Shanghai University Shanghai 200072People's Republic of China

This paper presents a new synchronization method of the time-delay chaotic system and its application in medical image encryption. Compared with the existing techniques, the error system is greatly simplified because many coupled items can be considered zero items. An improved image encryption scheme based on a dynamic block is proposed. This scheme divides the image into dynamic blocks, and the number of blocks is determined by a previous block cipher. Numerical simulations are provided to illustrate the effectiveness of the proposed method.

关键词： Time-delay chaotic system Zero items Medical image encryption Chaos synchronization

High-Temperature Fatigue Behavior of Inertia Friction Welded Joints of GH4065A Ni-Based Superalloy

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Acta Metallurgica Sinica(English Letters) 2024年第11期37卷 1935-1946页

作者： Xiaoguang Li Jiatao Liu Qing Liu Chunbo Zhang hang liang Lei Cui Yongchang Liu School of Materials Science and Engineering Tianjin UniversityTianjin300072China AECC Shenyang Liming Aero-Engine Co. LtdShenyang110043China Harbin Welding Institute Co. LtdHarbin150028China Tianjin Key Laboratory of Advanced Joining Technology Tianjin300072China

In this work,the novel Ni-based superalloy GH4065A inertia friction welding(IFW)joints were subjected to the post-welding heat treatments(PWHT)at 730℃for 5 h or 760℃for 5 h,and the differences in microstructure characteristics,local mechanical properties,and fatigue failure life were ***,based on the high-temperature low-cycle fatigue testing and characterization results,the correlation between the microstructure characteristics and low-cycle fatigue damage behavior was systematically *** was found that there were smaller grains in the thermo-mechanically affected zone(TMAZ)than in the weld zone and heat-affected zone(HAZ),and the boundary region between TMAZ and HAZ was the fatigue failure position of IFW joints under the high-temperature low-cycle fatigue *** fatigue testing results showed that the high-temperature fatigue performance for GH4065A IFW joints degenerated with the increase in PWHT *** existed cyclic softening and inhomogeneous fatigue damage in an IFW joint,which was more significant under the 760℃5 h PWHT ***,dislocation tangles and cells formed in the boundary region between TMAZ and HAZ under the fatigue *** difference in grain size after the IFW process and the inhomogeneousγ′phrase re-precipitation after the PWHT in the boundary region between TMAZ and HAZ resulted in the local inhomogeneous strengthening,corresponding to uneven plastic deformation and fatigue failure behavior under the fatigue loadings.

关键词： Inertia friction welding GH4065A alloy Low-cycle fatigue Post-welding heat treatment Fatigue behavior

New constraints on exotic spin-dependent interactions with an ensemble-NV-diamond magnetometer

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National Science Review 2023年第7期10卷 107-113页

作者： hang liang Man Jiao Yue Huang Pei Yu Xiangyu Ye Ya Wang Yijin Xie Yi-Fu Cai Xing Rong Jiangfeng Du CAS Key Laboratory of Microscale Magnetic Resonance and School of Physical Sciences University of Science and Technology of China CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of China Hefei National Laboratory University of Science and Technology of China CAS Key Laboratory for Research in Galaxies and Cosmology Department of Astronomy University of Science and Technology of China School of Astronomy and Space Science University of Science and Technology of China

Laboratory search of exotic interactions is crucial for exploring physics beyond the standard *** report new experimental constraints on two exotic spin-dependent interactions at the micrometer scale based on ensembles of nitrogen-vacancy(NV) centers in diamond.A thin layer of NV ele ctronic spin ensembles is synthesized as the solid-state spin quantum sensor,and a lead sphere is taken as the interacting nucleon *** result establishes new bounds for two types of exotic spin interactions at the micrometer *** an exotic parity-odd spin-and velocity-dependent interaction,improved bounds are set within the force range from 5 to 500 μ*** upper limit of the corresponding coupling constant gAegVNat 330 μm is more than 1000-fold more stringent than the previous *** the P,T-violating scalar-pseudoscalar nucleon-electron interaction,improved constraints are established within the force range from 6 to 45 μ*** limit of the corresponding coupling constant gSNgPeis improved by more than one order of magnitude at 30μ*** work demonstrates that a solid-state NV ensemble can be a powerful platform for probing exotic spin-dependent interactions.

关键词： quantum sensing exotic interaction diamond nitrogen-vacancy center beyond the standard model

Applanoids A—E as the First Examples of C-15/C-20 Michael Adducts in Ganoderma Triterpenoids and Their PXR Agonistic Activity

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Chinese Journal of Chemistry 2022年第22期40卷 2633-2641页

作者： Hai-Guo Su hang-Fei liang Gui-Lin Hu Lin Zhou Xing-Rong Peng Hui-Chang Bi Ming-Hua Qiu Guangdong Provincial Key Laboratory of New Drug Design and Evaluation School of Pharmaceutical SciencesSun Yat-sen UniversityGuangzhouGuangdong510006China State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China NMPA Key Laboratory for Research and Evaluation of Drug Metabolism&Guangdong Provincial Key Laboratory of New Drug Screening School of Pharmaceutical SciencesSouthern Medical UniversityGuangzhouGuangdong 510515China

Ganoderma triterpenoids(GTs),a class of major active constituents of Ganoderma fungi,possess diverse structures and remarkable *** the present study,nine new GTs,namely applanoids A—I(1—9),were isolated from the medicinal fungus of Ganoderma *** structures including absolute configurations were established by comprehensive spectroscopic analyses and ECD *** A—E(1—5)represent the first example of GTs with 6/6/5/6/5 pentacyclic system and the formation of the ether ring between C-15 and C-20 involves Michael addition ***,compounds 1—8 were evaluated for their human pregnane X receptor(hPXR)agonistic activity using dual-luciferase reporter gene assay,and the results showed that compounds 1,2 and 4 can dose-dependently activate *** investigation further illustrated the structural diversity of GTs and provided new insights for searching PXR agonists from GTs.

关键词： Ganoderma applanatum Lanostane triterpenoids Michael adducts Structure elucidation Pregnane X receptor

Hedgehog promotes cell proliferation in the midgut of silkworm,Bombyx mori

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Insect Science 2020年第4期27卷 697-707页

作者： Shun-Qin Zhu Ya-Jun Zhang Muhammad Nadeem Abbas Xiang-Wei Hao Yu-Zu Zhao hang-Hua liang Hong-Juan Cui Li-Qun Yang State Key Laboratory of Silkworm Genome Biology Southwest UniversityChongqingChina School of Life Sciences Southwest UniversityChongqingChina Chongqing Engineering Laboratory of Targeted and Innovative Therapeutics Chongqing Key Laboratory of Kinase Modulators as Innovative MedicineIATTIChongqing University of Arts and SciencesChongqingChina

The Hedgehog(Hh)signaling pathway is one o f the major regulators of embryonic development and tissue homeostasis in multicellular ***,the role of this pathway in the silkworm,especially in the silkworm midgut,remains poorly ***,we report that Bombyx mori Hedgehog(BmHh)is expressed in most tissues of silkworm larvae and that its functions are well-conserved throughout *** further demonstrate that the messenger RNA o f four Hh signaling components,BmHh ligand,BmPtch receptor,signal transducer BmSmo and transcription factor BmCi,are all upregulated following Escherichia coli or Bacillus thuringiensis infection,indicating the activation o f the Hh ***,midgut cell proliferation is strongly ***,the repression of Hh signal transduction with double-stranded RNA or cyclopamine inhibits the expression o f BmHh and BmCi and reduces cell ***,these findings provide new insights into the Hh signaling pathway in the silkworm,***.

关键词： cell proliferation cyclopamine Hedgehog midgut silkworm

Rituximab induction therapy in highly sensitized kidney transplant recipients

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Chinese Medical Journal 2011年第13期124卷 1928-1932页

作者： YIN hang WAN Hao HU Xiao-peng LI Xiao-bei WANG Wei LIU hang REN liang Zhang Xiao-dong Kidney Transplantation Program Department of Urology BeijingChao-Yang Hospital Capital Medical University Beijing 100020China

Background The number of highly sensitized patients is rising, The present study aimed to investigate the safety and efficacy of rituximab in highly sensitized kidney transplant recipients. and sensitization can lead to renal transplant failure. renal transplantation following induction therapy with Methods Seven highly sensitized kidney transplant recipients who underwent rituximab therapy from December 2008 to December 2009 were retrospectively analyzed. There were 3 men and 4 women, with a mean age of 38.5 years （range, 21-47 years）. The duration of hemodialysis was 3-12 months, with a mean duration of 11 months. For 4 patients, this was the second transplant; the previous graft survival time was 2-11 years, with a mean survival time of 5.8 years. All the female recipients had history of multiple pregnancies, and all patients had previously received blood transfusions. All donors were men, with a mean age of 32.5 years （range, 25-37 years）. In 2 of the 7 patients, both class I and class II of panel reactive antibody were high; the remaining 5 patients showed either high in class I or in class II of panel reactive antibody. The mean panel reactive antibody value was 31% for class I and 51% for class II respectively. The donors and the recipients had the same blood type, with low lymphocyte cytotoxicity ranging from 2% to 5%. The human leukocyte antigen （HLA） mismatch numbers were from 2 to 4. All patients received tacrolimus （0.1 ***^-1 .d^-1） and mycophenolate mofetil （750 mg twice per day） orally 3 days prior to surgery. All patients received a single dose of 600 mg rituximab （375 mg/m^2） infusion on the day before surgery and polyclonal antibody （antithymocyte globulin） on the day of surgery. Postoperative creatinine, creatinine clearance rate, and occurrence of rejection by pathological biopsy confirmation were monitored. Results No patient had delayed graft function after surgery. Two patients had acute rejection, one on day 7 and the other on day 13 post-s

关键词： kidney transplant highly sensitized rituximab

Monitoring immune function after rapid corticosteroid reduction in kidney transplant recipients

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Chinese Medical Journal 2011年第5期124卷 679-682页

作者： LI Shi-hai WANG Wei HU Xiao-peng YIN hang REN liang YANG Xiao-yong LIU hang Zhang Xiao-dong Department of Urology Beijing Chaoyang Hospital of Capital Medical University Beijing 100020 China

Background Long-term use of steroid with large dosage might cause many adverse effects in kidney transplant patients; reducing steroid dosage to a low level for maintenance is helpful in avoiding the side-effects, but meanwhile, acute rejection may rise to be a main concern. The present research monitored the immune function changes and the incidence of acute rejection and infection after rapid steroid reduction to investiclate the safety of this *** A prospective trial was conducted, using tacrolimus and mycophenolate mofetil as the basic immunosuppressive regimen, in addition to antibody induction with basiliximab. Corticosteroid dosage was rapidly reduced to 10 mg/d seven days post-transplantation in the experimental group, and the standard corticosteroid therapy was employed in the control group. Patient immunity was monitored by the Immune Cell Function Assay pre- and two weeks post-transplantation. The incidence of acute rejection and infection were compared between the experimental and control *** Comparison of intracellular adenosine triphosphate （iATP） values detected two weeks post-transplantation for the control group （（324±45） ng/ml） and the experimental group （（345±91） ng/ml） did not reveal a significant difference （P 〉0.05）. The incidence of acute rejection was analogous between groups （P 〉0.05）, while an increased incidence of infection was observed in the control group （53% （n=-16）） versus the experimental group （22% （n=-6）, P 〈0.05）. Overall, recipients in the control group had longer and more recurrent infections than those in the experimental group （P 〈0.05）. Patients in the control group had a lower immune response （（235±35） ng/ml） than those in the experimental group （（286±16） ng/ml） when infection occurred （P 〈0.05）.Conclusion Rapid reduction of steroid early after kidney transplantation does not lead to a significant rise in patient immunity. It is a safe and effective therapy for kidney transplant patients.

关键词： kidney transplantation corticosteroid reduction acute rejection immune cell function assay infection

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氧化铝陶瓷内衬钢管的防垢和耐腐蚀性能研究

热加工工艺 2022年第18期51卷 80-83页

作者：梁航国家石油天然气管材工程技术研究中心陕西宝鸡721008 宝鸡石油钢管有限责任公司陕西宝鸡721008 陕西省高性能连续管重点试验室陕西宝鸡721008

通过对普通钢管进行自蔓延高温处理,制备了自蔓延高温内衬陶瓷钢管。采用防垢试验、腐蚀试验,对比研究了陶瓷内衬钢管和普通钢管的防垢和耐腐蚀性能。结果表明,经自蔓延处理后,钢管的防垢性能比普通钢管的提高180%,在相同腐蚀条件下,普... 详细信息

通过对普通钢管进行自蔓延高温处理,制备了自蔓延高温内衬陶瓷钢管。采用防垢试验、腐蚀试验,对比研究了陶瓷内衬钢管和普通钢管的防垢和耐腐蚀性能。结果表明,经自蔓延处理后,钢管的防垢性能比普通钢管的提高180%,在相同腐蚀条件下,普通钢管的质量损失率达到氧化铝陶瓷内衬复合钢管的100倍以上。

关键词：防垢性能耐腐蚀性氧化铝陶瓷陶瓷内衬复合管