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Deep 3D mesh watermarking with self-adaptive robustness

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Cybersecurity 2023年第2期6卷 75-88页

作者： Feng Wang hang Zhou han Fang Weiming Zhang Nenghai Yu University of Science and Technology of China HefeiChina Simon Fraser University VancouverCanada National University of Singapore Kent RidgeSingapore

Robust 3D mesh watermarking is a traditional research topic in computer graphics,which provides an efficient solution to the copyright protection for 3D meshes.Traditionally,researchers need manually design watermarking algorithms to achieve suffcient robustness for the actual application scenarios.In this paper,we propose the first deep learning-based 3D mesh watermarking network,which can provide a more general framework for this problem.In detail,we propose an end-to-end network,consisting of a watermark embedding sub-network,a watermark extracting sub-network and attack layers.We employ the topology-agnostic graph convolutional network(GCN)as the basic convolution operation,therefore our network is not limited by registered meshes(which share a fixed topology).For the specific application scenario,we can integrate the corresponding attack layers to guarantee adaptive robustness against possible attacks.To ensure the visual quality of watermarked 3D meshes,we design the curvature consistency loss function to constrain the local geometry smoothness of watermarked meshes.Experimental results show that the proposed method can achieve more universal robustness while guaranteeing comparable visual quality.

关键词： 3D mesh watermarking Graph convolution network Attack layer

Adaptive Sliding Mode Control Method for Onboard Supercapacitors System

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Computer Systems Science & Engineering 2022年第3期40卷 1099-1108页

作者： Yanzan han hang Zhou Zengfang Shi Shuang Liang Department of Mechanical and Electrical Henan Polytechnic InstituteNanyang473000China University of Florence Firenze50041Italy

Urban rail trains have undergone rapid development in recent years due to their punctuality,high capacity and energy efficiency.Urban trains require frequent start/stop operations and are,therefore,prone to high energy losses.As trains have high inertia,the energy that can be recovered from braking comes in short bursts of high power.To effectively recover such braking energy,an onboard supercapacitor system based on a radial basis function neural networkbased sliding mode control system is proposed,which provides robust adaptive performance.The supercapacitor energy storage system is connected to a bidirectional DC/DC converter to provide traction energy or absorb regenerative braking energy.In the Boost and Buck modes,the state-space averaging method is used to establish a model and perform exact linearization.An adaptive sliding mode controller is designed,and simulation results show that it can effectively solve the problems of low energy utilization and large voltage fluctuations in urban rail electricity grids,and maximise the recovery and utilization of regenerative braking energy.

关键词： Energy control on-board supercapacitor neural sliding mode control urban rail train

Distortion minimization for multimedia transmission in NOMA HAP-UAV integrated aerial access networks

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Chinese Journal of Aeronautics 2022年第9期35卷 81-94页

作者： Guobin Zhang Zhu han hang XIN Xin WEI Boya DI School of Electrical Engineering and Intelligentization Dongguan University of TechnologyDongguan 523808China Department of Electrical and Computer Engineering and Department of Computer Science University of HoustonTX77004USA School of Computer Science and Technology Dongguan University of TechnologyDongguan 523808China Department of Computing Imperial CollegeLondon SW72AzUK

Aerial access networks have been envisioned as a promising 6G solution to enhance the ground communication systems in both coverage and capacity. To better utilize the spectrum and fully explore different channel characteristics, this paper constructs an integrated network comprising the High Altitude Platform(HAP) and Unmanned Air Vehicles(UAVs) with the NonOrthogonal Multiple Access(NOMA) technology. In order to improve the transmission quality of images and videos, a power management scheme is proposed to minimize the distortion of the transmissions from the HAP and UAVs to the terminals. The power control is formulated as a non-convex problem constrained by the maximal transmit power and the minimal terminal rate requirements. The variable substitution and the first-order Tailor’s expansion is used to transform it into a sequence of convex problems, which are subsequently solved through the gradient projection method. Simulation demonstrates the signal distortion and error rate improvement achieved by the proposed algorithm.

关键词： Aerial Access Networks High Altitude Platform Non-Orthogonal Multiple Access Sixth-Generation Unmanned Air Vehicles

Nrf2-mediated ferroptosis of spermatogenic cells involved in male reproductive toxicity induced by polystyrene nanoplastics in mice

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第4期25卷 307-323页

作者： Xufeng FU Hang HAN Hong YANG Bo XU Wenjie DAI Ling LIU Tiantian HE Xing DU Xiuying PEI Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education School of Basic Medical SciencesNingxia Medical UniversityYinchuan 750004China Key Laboratory of Reproduction and Genetics in Ningxia Ningxia Medical UniversityYinchuan 750004China

Microplastics(MPs)and nanoplastics(NPs)have become hazardous materials due to the massive amount of plastic waste and disposable masks,but their specific health effects remain uncertain.In this study,fluorescence-labeled polystyrene NPs(PS-NPs)were injected into the circulatory systems of mice to determine the distribution and potential toxic effects of NPs in vivo.Interestingly,whole-body imaging found that PS-NPs accumulated in the testes of mice.Therefore,the toxic effects of PS-NPs on the reproduction systems and the spermatocytes cell line of male mice,and their mechanisms,were investigated.After oral exposure to PS-NPs,their spermatogenesis was affected and the spermatogenic cells were damaged.The spermatocyte cell line GC-2 was exposed to PS-NPs and analyzed using RNA sequencing(RNA-seq)to determine the toxic mechanisms;a ferroptosis pathway was found after PS-NP exposure.The phenomena and indicators of ferroptosis were then determined and verified by ferroptosis inhibitor ferrostatin-1(Fer-1),and it was also found that nuclear factor erythroid 2-related factor 2(Nrf2)played an important role in spermatogenic cell ferroptosis induced by PS-NPs.Finally,it was confirmed in vivo that this mechanism of Nrf2 played a protective role in PS-NPs-induced male reproductive toxicity.This study demonstrated that PS-NPs induce male reproductive dysfunction in mice by causing spermatogenic cell ferroptosis dependent on Nrf2.

关键词： Polvstyrene nanoplastics(PS-NPs) Reproductive toxicity Ferroptosis Nuclear factor ervthroid 2-related factor 2(Nrf2)

Redox-etching induced porous carbon cloth with pseudocapacitive oxygenic groups for flexible symmetric supercapacitor

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Journal of Energy Chemistry 2022年第1期31卷 136-143,I0005页

作者： Xu han Zi-hang Huang Fanjin Meng Baohua Jia Tianyi Ma Institute of Clean Energy Chemistry Key Laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials of Liaoning ProvinceCollege of ChemistryLiaoning UniversityShenyang 110036LiaoningChina Centre for Translational Atomaterials School of ScienceSwinburne University of TechnologyHawthornVIC 3122Australia

Constructing high-performance electrodes with both wide potential window(e.g.≥2 V in aqueous electrolyte)and excellent mechanical flexibility represents a great challenge for supercapacitors.Because of the outstanding conductivity and flexibility,carb on cloth(CC)has show n unlimited prospects for constructing flexible electrodes,but is rarely used directly as electrode material due to its electrochemical inertness and small specific surface area.To tackle these two critical limitations,we design a novel redox-etching strategy to synthesize CC-based electrode with 3D interconnecting pore structure.The sponge-like highly porous CC was further activated by strong oxidant to form abundant oxygenic groups,which occupy the interior and surface of current collector to render substantial pseudocapacitance.The as-synthesized CC electrode yielded an impressive capacitance of 4035 mF cm^(-2) at 3 mA cm^(-2) and satisfying cycling durability in a wide potential range of-1-1 V vs.SCE,which surpass the majority of reported CC-based electrodes.A symmetric supercapacitor with stable voltage of 2 V is assembled and delivers remarkable energy density of 6.57 mWh cm^(-3).Significantly,the device demonstrates an unparalleled flexibility with no capacitive decay after 100 bending cycles.This facile chemical etching and post-treatment processes are designed for large-scale manufacturing of the CC electrodes by providing high surface area and abundant electrochemically active sites,promising for industry application.The innovative synthetic strategy ope ns up new opportunities for high-performance flexible en ergy storage.

关键词： Porous carbon fiber Hierarchical pores Oxygenic groups Wide potential window High-performance supercapacitors

Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus

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Acta Pharmaceutica Sinica B 2022年第2期12卷 723-734页

作者： hang Qi Yuntao Shi han Wu Canyang Niu Xiaoying Sun KeWei Wang Department of Pharmacology School of PharmacyQingdao UniversityQingdao 266021China State Key Laboratory of Natural and Biomimetic Drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Institue of Innovative Drugs Qingdao UniversityQingdao 266021China

Genetic gain-of-function mutations of warm temperature-sensitive transient receptor potential vanilloid 3(TRPV3)channel cause Olmsted syndrome characterized by severe itching and keratoderma,indicating that pharmacological inhibition of TRPV3 may hold promise for therapy of chronic pruritus and skin diseases.However,currently available TRPV3 tool inhibitors are either nonselective or less potent,thus impeding the validation of TRPV3 as therapeutic target.Using whole-cell patch-clamp and single-channel recordings,we report the identification of two natural dicaffeoylquinic acid isomers isochlorogenic acid A(IAA)and isochlorogenic acid B(IAB)that selectively inhibit TRPV3 currents with IC50 values of 2.7±1.3 and 0.9±0.3μmol/L,respectively,and reduce the channel open probability to 3.7±1.2%and 3.2±1.1%from 26.9±5.5%,respectively.In vivo evaluation confirms that both IAA and IAB significantly reverse the ear swelling of dermatitis and chronic pruritus.Furthermore,the isomer IAB is able to rescue the keratinocyte death induced by TRPV3 agonist carvacrol.Molecular docking combined with site-directed mutations reveals two residues T636 and F666 critical for the binding of the two isomers.Taken together,our identification of isochlorogenic acids A and B that act as specific TRPV3 channel inhibitors and gating modifiers not only provides an essential pharmacological tool for further investigation of the channel pharmacology and pathology,but also holds developmental potential for treatment of dermatitis and chronic pruritus.

关键词： TRPV3 Dicaffeoylquinic acid Gate modifier Chronic pruritus Dermatitis Olmsted syndrome Ear swelling

A novel anticancer property of Lycium barbarum polysaccharide in triggering ferroptosis of breast cancer cells

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2022年第4期23卷 286-299页

作者： Xing DU Jingjing Zhang Ling LIU Bo XU Hang HAN Wenjie DAI Xiuying PEI Xufeng FU Shaozhang HOU Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education School of Basic Medical SciencesNingxia Medical UniversityYinchuan 750004China Department of Clinical Pathology School of Basic Medical SciencesNingxia Medical UniversityYinchuan 750004China

Breast cancer is one of the most malignant tumors and is associated with high mortality rates among women.Lycium barbarum polysaccharide(LBP)is an extract from the fruits of the traditional Chinese herb,L.barbarum.LBP is a promising anticancer drug,due to its high activity and low toxicity.Although it has anticancer properties,its mechanisms of action have not been fully established.Ferroptosis,which is a novel anticancer strategy,is a cell death mechanism that relies on iron-dependent lipid reactive oxygen species(ROS)accumulation.In this study,human breast cancer cells(Michigan Cancer Foundation-7(MCF-7)and MD Anderson-Metastatic Breast-231(MDA-MB-231))were treated with LBP.LBP inhibited their viability and proliferation in association with high levels of ferroptosis.Therefore,we aimed to ascertain whether LBP reduced cell viability through ferroptosis.We found that the structure and function of mitochondria,lipid peroxidation,and expression of solute carrier family 7 member 11(SLC7 A11,also known as x CT,the light-chain subunit of cystine/glutamate antiporter system X_(c)^(-))and glutathione peroxidase 4(GPX4)were altered by LBP.Moreover,the ferroptosis inhibitor,Ferrostatin-1(Fer-1),rescued LBP-induced ferroptosis-associated events including reduced cell viability and glutathione(GSH)production,accumulation of intracellular free divalent iron ions and malondialdehyde(MDA),and down-regulation of the expression of x CT and GPX4.Erastin(x CT inhibitor)and RSL3(GPX4 inhibitor)inhibited the expression of x CT and GPX4,respectively,which was lower after the co-treatment of LBP with Erastin and RSL3.These results suggest that LBP effectively prevents breast cancer cell proliferation and promotes ferroptosis via the x CT/GPX4 pathway.Therefore,LBP exhibits novel anticancer properties by triggering ferroptosis,and may be a potential therapeutic option for breast cancer.

关键词： Lycium barbarum polysaccharide Ferroptosis Breast cancer cells xCT Glutathione peroxidase 4(GPX4)

Special topic on research frontiers in porous organic polymers

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Science China Chemistry 2017年第8期60卷 997-998页

作者： Bao-Hang HAN Dong Wang National Center for Nanoscience and Technology Beijing 100190China Institute of Chemistry Chinese Academy of SciencesBeijing 100190China

Porous organic polymers(POPs)are materials with covalently bonded,thermally stable backbones that exhibit large accessible surface areas and intriguing properties applicable to fields such as gas storage and separation,catalysis,and optoelectronics.Compared to analogous inorganic porous materials,POPs feature a wider range of pore size,larger surface area,readily available functional groups for post-synthesis functionalization,etc.,which enables their design for targeted applications.

关键词：有机聚合物多孔材料持久性有机污染物专题 POPs 表面积热稳定官能团

Evaluation on Cycle Performance of R161 as a Drop-in Replacement for R407C in Small-Scale Air Conditioning Systems

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Journal of Thermal Science 2022年第6期31卷 2068-2076页

作者： FANG Yibo WU Mei GUO Zhikai NI hang han Xiaohong CHEN Guangming Key Laboratory of Refrigeration and Cryogenic Technology of Zhejiang Province Institute of Refrigeration and CryogenicsZhejiang UniversityHangzhou 310027China State Key Lab for Fluorine Greenhouse Gases Replacement and Control Treatment Zhejiang Research Institute of Chemical IndustryHangzhou 310023China

In this work, with excellent environmental characteristics and thermodynamic properties, R161 is considered as a drop-in replacement of R407C used in small-scale air conditioning systems. In order to study the potential of R161 in the application, the theoretical and experimental cycle performances of R161 and R407C were compared under different working conditions. The experimental results agreed well with theoretical results. In the experiment, COPs of R161 were about 15% higher than those of R407C. The compressor power consumptions of R161 were about 18% lower than those of R407C. The discharge temperatures of R161 were about 0-4℃ lower than those of R407C. Besides, the annual electric consumption of a small-scale split air conditioning in Beijing, Shanghai and Hongkong could be reduced by about 19.5%, when the working fluid was changed from R407C to R161. Overall, the results indicated that R161 has a better cycle performance and good compatibility with the existing systems designed for R407C.

关键词： R161 R407C drop-in replacement small-scale air conditioning system