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A review on g-C_(3)N_(4)decorated with silver for photocatalytic energy conversion

Chinese Chemical Letters 2024年第2期35卷 187-196页

作者： Ziyu Pan Wufan Ding hanchun chen Haodong Ji Eco-environment and Resource Efficiency Research Laboratory School of Environment and EnergyPeking University Shenzhen Graduate SchoolShenzhen 518055China

Artificial photocatalytic energy conversion is considered as the most potential strategy for solving the increasingly serious energy crisis and environmental pollution problems by directly capturing solar energy.Therefore,high efficiency photocatalyst has drawn significant research attention in recent years.Due to the excellent electronic,optical,structural,and physicochemical performances,silver-based g-C_(3)N_(4)have become promising photocatalysts.This review emphasizes the recent progresses and challenges on g-C_(3)N_(4)decorated with silver for photocatalytic energy conversion.The extensive use of g-C_(3)N_(4)decorated with silver in diverse photocatalytic reactions,including hydrogen evolution,pollutant degradation and carbon dioxide reduction,is also fully introduced.In addition,we propose the perspectives of g-C_(3)N_(4)decorated with silver on photocatalytic applications.We hope that this review will shed some light on the photocatalytic energy conversion of g-C_(3)N_(4)decorated with silver.

关键词： g-C_(3)N_(4) Silver-modified g-C_(3)N_(4) Photocatalytic energy conversion H_(2)evolution Pollutant degradation CO_(2)reduction

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Endoscopic anatomical study on anterior communicating artery aneurysm surgery by endonasal transphenoidal approach

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Chinese Neurosurgical Journal 2016年第4期2卷 187-193页

作者： Junwei Ma Zhimin Wang Niankai Zhang Shengshan Li Dongyi Jiang hanchun chen Department of Neurosurgery Suzhou Kowloon Hospital Affiliated Shanghai Jiao Tong University Suzhou 266021 China Department of Otolaryngology Affiliated Hospital of Qingdao University Medical Colledge Qingdao 266003China Department of Neurosurgery Chinese Medicine Hospital of GaomiGaomi 261500 China

Endonasal transphenoidal approach by neuroendoscopy has its own advantage, such as direct access, invasive, better visualization of the anterior communicating artery aneurysm and so on. The study is to provide anatomical knowledge for anterior communicating artery aneurysm surgery by endonasal transphenoidal approach with neuroendoscopy. Take 10 skull base specimens, observe and measure the anatomical structures around anterior communicating artery. Take 10 cadaveric heads, simulate the anterior communicating artery aneurysm surgery with neuroendoscopy by endonasal transphenoidal approach. Find the natural opening of sphenoid sinus, then open the skull base, expand bone window in anterior skull base. After that, cut off the dura, find the optic nerve, optic chiasm, cisterna lamina terminalis, anterior cerebral artery, a portion of frontal lobe, anterior communicating artery complex and its important branches, such as heubner artery, hypothalamic artery, orbitofrontal artery and so on. Lift up anterior communicating artery complex and seperate arachnoid in cisterna lamina terminalis, the lamina terminalis is exposed. Block bilateral A1 of anterior cerebral artery with aneurysm clip, the anterior communicating artery complex and its important branches are in view, so we can clip anterior communicating artery aneurysm safely. Anterior communicating artery aneurysm surgery can be finished with neuroendoscopy by endonasal transphenoidal approach. The vital structures can be clearly observed with neuroendoscopy. The rhombus anatomic region formed by bilateral olfactory nerve and optic nerve is a safe surgical area. According to the calculation, the safe surgical area is about 161.48 ± 12.78 mm2. Measure the distance between the important anatomic structures in the rhombus anatomic region. By means of SPSS 17 Statistical analysis software, the measuring distance is expressed with (x ± S)mm. The anterior communicating aneurysm surgery by endonasal transphenoidal approach with neuroendoscopy has its own advantage, such as

关键词： Endoscope Anterior communicating artery Cerebral aneurysm Anatomy

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腹茧症腹膜透析后腹腔脓肿致肠穿孔感染性休克患者的护理

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护理与康复 2024年第4期23卷 63-64,68页

作者：陈寒春曾颖浙江大学医学院附属第一医院浙江杭州310003

总结1例腹茧症腹膜透析后腹腔脓肿致肠穿孔感染性休克患者的护理经验。护理重点为:术前基于国家早期预警评分的感染性休克早期预警,术后再次发生感染性休克的快速响应,感染性休克患者的血液透析管理,加强肾病患者的营养支持管理。经过4... 详细信息

总结1例腹茧症腹膜透析后腹腔脓肿致肠穿孔感染性休克患者的护理经验。护理重点为:术前基于国家早期预警评分的感染性休克早期预警,术后再次发生感染性休克的快速响应,感染性休克患者的血液透析管理,加强肾病患者的营养支持管理。经过41 d的治疗与护理,患者康复出院。

关键词：腹茧症腹膜透析感染性休克

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Synthesis and biological characterization of the analogs of Huwentoxin-IV,a neuronal TTX-sensitive sodium channel Inhibitor

Synthesis and biological characterization of the analogs of ...

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生命的分子机器及其调控网络——2012年全国生物化学与...

作者： Meichun Deng Xuan Luo Liping Jiang hanchun chen Department of Biochemistry School of Biological Science and TechnologyCentral South University Key Laboratory of Protein Chemistry and Developmental Biology of the Ministry of Education College of Life SciencesHunan Normal University

Huwentoxin-Ⅳ(HWTX-Ⅳ) is a polypeptide neurotoxin isolated from the venom of the Chinese tarantula Ornithoctonus huwena. The toxin has a high proportion of basic residues,and it is cross-linked by three conserved intramolecular disulfide bonds.The linkage pattern of disulfide bridges in HWTX-ⅣisⅠ-Ⅳ,Ⅱ-Ⅴ,andⅢ-Ⅵ(Cys2-Cys17,Cys9-Cys24,and Cys16-Cys31) as assigned by partial reduction and sequence analysis.Composed of 35 residues and stabilized by intracellular disulfide bridges,the toxin adopts a typical inhibitor cystine knot(ICK) structural motif frequently emerging in spider toxins and conotoxins.It has been shown to

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Real-time monitoring of repair of DNA strand breakscontaining 3’-phosphate and 5’-hydroxyl termini using molecular beacon probes

Real-time monitoring of repair of DNA strand breakscontainin...

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湖南省生理科学会2013年度学术年会

作者： Changbei Ma Kemin Wang Kun Xia hanchun chen Hailun He Weimin Zeng School of Life Sciences Central South University State Key Lab of Chemo/Biosensing and Chemometrics Hunan University

DNA strand break repair plays a key role in protecting the genome from endogenous and exogenous DNA damage.Traditionally,it is assayed by denaturing gel electrophoresis and autoradiography,which are tedious and not sensitive.We report on the development of a sensitive and simple method for DNA repair assay based on DNA ligation using molecular beacon.Enzyme activity of T4 polynucleotide kinase is measured down to a limit of 0.002 unit/ml.The method not only provides a universal platform for monitoring DNA repair activities,but also shows great potential in biological research,drug discovery,and clinical diagnostics.

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Thymoquinone inhibits cervical cancer metastasis in vitro by targeting epithelial to mesenchymal transition associated transcription factors Twist1 and Zeb1

Thymoquinone inhibits cervical cancer metastasis in vitro by...

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2017年中国肿瘤标志物学术大会暨第十一届肿瘤标志物青...

作者： Jun Li Asaduzzaman Khan Chunli Wei Jingliang cheng hanchun chen Junjiang Fu Key Laboratory of Epigenetics and Oncology Research Center for Preclinical MedicineSouthwest Medical University

Cervical cancer is a major type of gynecological malignant tumor, of which the chemotherapeutic strategies are limited by its non-specific cytotoxicity and drug resistance. Thymoquinone（TQ）, a natural product has been reported to target vast number of signaling pathways in carcinogenesis in different cancers, and hence regarded as a promising anticancer molecule. Inhibition of epithelial to mesenchymal transition（EMT） regulators is anical cancer cell lines, SiHa and CaSki, to investigate its effects on EMT-regulatory important cancer therapeutic approach. Here TQ was used to treat cervproteins and cancer metastasis. We found that TQ has time-dependent and dose-dependent cytotoxic effect, as well as it inhibits the migration and invasion process in different cervical cancer cells. Mechanistically TQ treatment inhibited the expression of Twist1, Zeb1 expression, and increased E-Cadherin expression. Luciferase reporter assay showed that TQ decreases the Twist1 and Zeb1 promoter activity, indicating that Twist1 and Zeb1 might be the direct target of TQ. TQ also increased cellular apoptosis in some extent, but apoptotic genes/proteins we tested were not affected. We summarize that TQ inhibits the migration and invasion of cervical cancer cells probably via Twist1/ECadherin/EMT or/and Zeb1/E-Cadherin/EMT among other signaling pathways.

关键词： Cervical cancer Metastasis Epithelial to mesenchymal transition Twist1 Zeb1 E-Cadherin Thymoquinone

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Transfected ISG15 inhibits the growth of liver cancer cells by increasing the expression of P53

Transfected ISG15 inhibits the growth of liver cancer cells ...

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生命的分子机器及其调控网络——2012年全国生物化学与...

作者： Xinxing Wan hanchun chen Md.Asaduzzaman Khan Aihua Xu Fulan Yan Yunyi Zhang Dianzheng Zhang Department of Biochemistry School of Biological Science and TechnologyCentral South University Department of Biochemistry/Molecular Biology Philadelphia College of Osteopathic Medicine

Hepatocellular carcinoma(HCC) is one of the most prevalent tumors worldwide.It is very important for us to research the pathogenic mechanism and treatment of HCC.The HCC cell line HepG2 was chosen in this study,because it expresses wild-type tu-mour-suppressor gene protein53(P53),which can be helpful to inivestigate the relation-ship between ISG15 and p53.p53 is one of the most important tumor suppressors and is considered as the guardian of the genome,and it is the key regulator of cell survival and cell

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Huwentoxin-XVI,a specific N-type calcium channel blocker from tarantula venom,produces dose-dependent antinociception in rats

Huwentoxin-XVI,a specific N-type calcium channel blocker fro...

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生命的分子机器及其调控网络——2012年全国生物化学与...

作者： Meichun Deng Yuanyuan Wu Tianfu Cai Zhenghua Sun hanchun chen Yucheng Xiao Songping Liang Department of Biochemistry School of Biological Science and TechnologyCentral South University Key Laboratory of Protein Chemistry and Developmental Biology of the Ministry of Education College of Life SciencesHunan Normal University

N-type calcium channels play important roles in the control of neurotransmission release.Their selective blockers are believed to be potential drugs for treating chronic pain.Spider venoms are known to contain several classes of toxins that are used as an efficient means to capture their prey or to defend themselves against predators.These toxins are of interest as tools for studying neurophysiology and as potential lead structures for pharmaceutics and insecticides.In this study,a novel neurotoxin named

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Resveratrol mediated inhibition of leukemic cell growth involves the apoptotic mechanism and some extents of modification in anti-oxidant enzymes

Resveratrol mediated inhibition of leukemic cell growth invo...

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生命的分子机器及其调控网络——2012年全国生物化学与...

作者： Md.Asaduzzaman Khan Xinxing Wan Mousumi Tania Aihua Xu Dianzheng Zhang hanchun chen Department of Biochemistry School of Biological Science and TechnologyCentral South.University Philadelphia College of Osteopathic Medicine Department of Biochemistry School of Biological Science and TechnologyCentral South University

Background:Leukemia is one of the most common and deadly cancers world-wide.Most forms of leukemia are treated with pharmaceutical medication,typically combined into a multi-drug chemotherapy regimen.Resveratrol(RSV) is a natural polyphenol which has been reported to be effective against cancers,but its mechanism of action is not com-pletely understood currently.In this study we have investigated the mechanism of RSV’s action on the anti-oxidative axis in leukemic cells.Methods:The chronic myelogenous leukemic(CML) cell lines K.-562,KT-1/A3,KT-1/A3R and acute myelogenous leukemic(AML) cell line HL-60 were

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COVID-19 disease and malignant cancers: The impact for the furin gene expression in susceptibility to SARS-CoV-2

COVID-19 disease and malignant cancers: The impact for the f...

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2021年中国肿瘤标志物学术大会暨第十五届肿瘤标志物青...

作者： Jingliang cheng dabing Li Xiaoyan Liu lianmei Zhang Xianmao chen shuguang Liu Jiewen Fu shangyi Fu hanchun chen Junjiang Fu Southwest Medical University 南京医科大学附属淮安第一人民医院 Baylor College of Medicine 中南大学

Furin is a proprotein convertase that activates different kinds of regulatory proteins, including SARS-CoV-2 spike protein which contains an additional furin-specific cleavage site. It is essential to foretell the cancer patients’ susceptibility to SARS-CoV-2 and the disease outcomes through evaluating furin expressions in tumor tissues. In this study, we analyzed the furin expression, methylation,mutations, functional enrichment, survivals and COVID-19 outcomes in normal and tumor tissues through online databases and IHC. As results, furin presented the biased expression profiles in normal tissues, showing 12.25-fold higher than ACE2 in the lungs. The furin expressions in tumors were significantly increased in ESCA and TGCT;decreased in DLBC and THYM, indicating furin may play critical roles for COVID-19 viral entry in these cancer patients. Line with furin over/downexpression, furin promoter hypo-/hyper-methylation may be the regulatory mechanism and in pathogenesis of ESCA and THYM. Furthermore, usage of FURIN-201 isoform with functional domains(Proprotein, Peptidase8 and S8ro-domain) is the highest in all cancer types,demonstrating this isoform role in tumorigenesis and SARS-Cov-2 entry into tumor tissues. Meanwhile, furin mutation frequency was highest in UCES, and its mutation elevated ACE2 expression in LUAD and UCEC, reduced ACE2 expression in COAD;elevated HSPA5 expression in PAAD;elevated TMPRSS2 expression in BRCA. These results showed that furin mutations mostly increased expression of ACE2, HSPA5 and TMPRSS2 in some cancers, indicating the possible network roles of furin mutation for COVID-19 viral entry for cancer patients. In addition, high expression of furinwas significantly reverse correlated with long overall survival(OS) in LGG;significantly correlated with long OS in COAD and KIRC, indicating that it may serve as a favorable prognostic marker for those cancer patient’s survivals. Moreover, GO and KEGG demonstrated that furin was mostly enriched in the genes for metabolic and biosynthetic proc

关键词： COVID-19 furin malignant cancers SARS-CoV-2 susceptibility

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