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In vitro and in vivo evaluation of the antiangiogenic activities of Trigonella foenum-graecum extracts

Asian Pacific Journal of Tropical Biomedicine 2017年第8期7卷 732-738页

作者： Zina A.Habib-martin hana m.hammad Fatma U.Afifi malek Zihlif Hamzeh J.Al-Ameer mohanad m.Saleh Ismail F.Abaza Zeyad D.Nassar Department of Biology School of ScienceThe University of Jordan Department of Pharmaceutical Sciences School of PharmacyThe University of Jordan Department of Pharmacology School of MedicineThe University of Jordan School of medicine and Freemasons Foundation Centre for men's Health University of Adelaide South Australian Health and medical Research Institute

Objective: To assess the antiangiogcnic activity of ***: Different fractions of fenugreek crude extracts were prepared and their antiangiogenic properties were assessed using the ex vivo rat aortic ring assay and in vivo chicken embryo chorioallantoic membrane(CAm) assay. They were investigated for their direct cytotoxic activity in the mCF7 cells using the mTT ***: The ethanol extract showed 100% inhibition of blood vessel outgrowth from primary tissue explants in the rat aortic ring assay at a concentration of 100μg/mL while the other extracts did not show significant antiangiogenic activity. The ethanol extract was therefore investigated at varying concentrations and exhibited a significant dose dependent effect. The CAm assay coincided with the results of the aortic ring assay as ethanol extract showed a significant inhibition of formation of new blood vessels. The extracts only showed anti-proliferative activity at the highest concentration of 400μg/mL towards mCF7 breast cancer cell lines in the mTT ***: Findings of the both assays confirmed that the ethanol extract inhibited vascularization significantly. Further studies on the ethanol extract would be beneficial in isolating the active ingredient responsible for the inhibition.

关键词： Fenugreek mCF7 Angiogenesis Rat aortic ring assay CAm assay mTT assay

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Enhancing the explosive characteristics of a Semtex explosive by involving admixtures of BCHmX and HmX

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Defence Technology（防务技术） 2020年第2期16卷 487-492页

作者： Ahmed Elbeih Ahmed K.Hussein Tamer Elshenawy Svatopluk Zeman Sara m.hammad Ahmad Baraka mohamed A.Elsayed mohamed Gobara Hesham Tantawy military Technical College Kobry ElkobbahCairoEgypt Technical Research Center CairoEgypt Institute of Energetic materials Faculty of Chemical TechnologyUniversity of PardubiceCzech Republic Faculty of Pharmacy University of CairoGizaEgypt

A well-known ternary plastic explosive,Czech Semtex 1H,contains a mixture of PETN and RDX softened by *** this work,BCHmX was used to replace PETN in Semtex 1H to form Sem-BC+*** addition,another mixture based on BCHmX and HmX as energetic fillers bonded by the polymeric matrix of Semtex 1H(Sem-BC+HmX)was *** particle size distribution of each individual explosive was determined to obtain the optimum mixing *** and impact sensitivities were *** velocity of detonation was reported practically and the detonation properties were calculated by EXPLO5 *** explosive strength of each sample was measured by the ballistic mortar *** conclusion confirms that the velocity of detonation of Sem-BC+HmX was the highest in comparison with the prepared ***-BC+RDX has the least impact and frictions ***-BC+RDX has higher detonation velocity,detonation properties and explosive strength than Semtex *** of BCHmX in Semtex 1H as a replacement for PETN is the candidate to produce a high performance advanced Czech plastic explosive.

关键词： Semtex Explosives Combustion Sensitivity Detonation Explosive strength

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Endoscopic assessment and management of early esophageal adenocarcinoma

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World Journal of Gastrointestinal Oncology 2014年第8期6卷 275-288页

作者： Ghassan m Hammoud Hazem.hammad Jamal A Ibdah Division of Gastroenterology and Hepatology University of Mis-souri Columbia MO 65212 United States

Esophageal carcinoma affects more than 450000people worldwide and the incidence is rapidly *** the United States and Europe,esophageal adenocarcinoma has superseded esophageal squamous cell carcinoma in its *** cancer has a high mortality rates secondary to the late presentation of most patients at advanced *** screening is recommended for patients with multiple risk factors for cancer in Barrett’s *** risk factors include chronic gastroesophageal reflux disease,hiatal hernia,advanced age,male sex,white race,cigarette smoking,and *** annual risk of esophageal cancer is approximately 0.25%for patients without dysplasia and 6%for patients with high-grade *** percent of all esophageal adenocarcinoma in the United States is early stage with disease confined to the mucosa or *** significant morbidity and mortality of esophagectomy make endoscopic treatment an attractive *** American Gastroenterological Association recommends endoscopic eradication therapy for patients with high-grade *** modalities for treatment of early esophageal adenocarcinoma include endoscopic resection techniques and endoscopic ablative techniques such as radiofrequency ablation,photodynamic therapy and *** therapy should be precluded to patients with no evidence of lymphovascular *** tumor recurrence is low after endoscopic therapy and is predicted by poor differentiation of tumor,positive lymph node and submucosal *** resection should be offered to patients with deep submucosal invasion.

关键词： Esophageal adenocarcinoma High grade dysplasia,endoscopic ultrasound Gastroesophageal reflux Barrett’s esophagus Chromoendoscopy Narrow band imaging Endoscopic mucosal resection Radiofrequency ablation

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Offshore Carbonate Facies Characterization and Reservoir Quality of miocene Rocks in the Southern margin of South China Sea

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Acta Geologica Sinica(English Edition) 2020年第5期94卷 1547-1561页

作者： hammad Tariq JANJUHAH Abubaker ALANSARI Department of Geology Shaheed Benazir Bhutto UniversitySheringal Upper DirKPKPakistan Department of Geology American University of BeirutRiad El-SolhBeirut11072020Lebanon Department of Geosciences University Technology PETRONAS32610PerakMalaysia

Carbonate rocks are important hydrocarbon reservoirs around the globe and in Southeast Asia a key one,particularly,is the Central Luconia *** the internal characteristics,distribution,geometry and lateral extent of these rocks is essential for exploration and production *** work on miocene carbonate reservoir facies,north of Bintulu,offshore Sarawak includes qualitative and quantitative analysis of photomicrographs and reservoir quality,considering especially ***,these carbonates are known as Cycles IV and V and are represented by eight major facies types(F-1 to F-8).They comprise:coated grain packstone(F-1)(av.Ф=3%,***=0.5 m D)(av=Average;?=total porosity,and Kh=permeability);massive coral lime grainstone(F-2)(av.Ф=14.7%,***=6 m D);oncolite lime grain-dominated packstone(F-3)(av.Ф=10%,***=4 m D);skeletal lime/dolo-packstone(F-4)(av.Ф=15%,***=4.6 m D);coral(platy)lime mud-dominated packstone(F-5)(av.Ф=4%,***=0.5 m D);coral(branching)lime-dominated pack-grainstone(F-6)(av.Ф=15%,***=1 m D);cross-bedded skeletal lime packstone(F-7)(av.Ф=20%,***=2 m D);and bioturbated carbonate mudstone/chalk(F-8)(av.Ф=8%,***=0.8 m D).Study of thin sections reveals that red algae,foraminifera,and corals are the dominant fossil components with a minor admixture of skeletal fragments of echinoderms,bivalves,bryozoans,and green *** parameters,e.g.,facies characterization,petrography,porosity–permeability value,and microporosity value were utilized to obtain a reliable reservoir *** microporosity value was quantified using digital image analysis software and is significant for recognition of good reservoir *** of the presence of microporosity against the total porosity in the carbonate rocks has improved the correlation coefficient(R2)value,which has increased from 0.51 to 0.82.

关键词： carbonates petrography grain types porosity-permeability hydrocarbons microporosity offshore Sarawak

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Coexistence and fluctuations phenomena with Davidson-like potentials in quadrupoleoctupole deformed nuclei

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Communications in Theoretical Physics 2021年第3期73卷 105-118页

作者： m m.hammad W H mansour E m El-maghraby H A motaweh Ayman A Aly Faculty of Science Mathematics DepartmentDamanhour UniversityEgypt Faculty of Science Physics DepartmentDamanhour UniversityEgypt

The energy spectra of three types of two-dimensional potentials(we will call them‘Davidson-like potentials’(DLPs)),characterized by four minima separated by barriers,are *** predictions for spectra and wave functions are obtained by using the nine-point finite-difference *** these potentials,with the existence of a single configuration,a transition of spectra,as a function of barrier height,is covered from tunneling splitting modes to fluctuations phenomena,with equal peaks wave functions,crossing to the spectra of purely anharmonic oscillator potentials(AOPs).A different type of phase transition occurs when two(or more)configurations *** the change of the parameters,a transition of spectra is covered from coexistence phenomena of two distinct quantum tunneling modes to fluctuations phenomena,with unequal peaks wave functions,crossing to the spectra of purely *** DLPs,a particular application of the coherent quadropole-octupole model to describe energy bands with alternating parity of the nuclei^(100)mo,^(146,148)Nd,^(148,150)Sm,^(220)Ra,^(220,222)Rn,and^(220,222)Th is *** global parametrization of the model for the selected nuclei is achieved.

关键词： quantum phase transitions fluctuations phenomena coherent quadrupole-octupole motion model coexistence phenomena

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Oxidation Resistance of the Aluminide Coating Formed on Carbon Steels

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Journal of materials Science & Technology 1997年第5期13卷 383-388页

作者： Soliman, H.m. Ohamed, K.E. Abd El-Azim, m.E. hammad, F.H. metallurgy Dept. Atomic Energy Authority Cairo Egypt

Low and medium carbon steels were aluminized by the pack aluminizing technique using halideactivated pure-Al and Fe-Al packs. The effect of mixture composition, aluminizing temperatureand time and C content of the steel substrate on the structure and thickness of the aluminidelayer, and on the oxidation resistance was investigated. The optimum oxidation resistance canbe achieved with a low carbon steel substrate when the intermetallic phases Fe3Al and FeAlform the surface of the aluminide layer. In this case, the Al concentration at the surface of thealuminide coating is at least ≥15 wt pct. Formation of high Al concentration phases (FeAl3 andFe2Al5) during aluminizing should be avoided as they tend to embrittle the aluminide layer andreduce its oxidation resistance.

关键词： OO Figure Oxidation Resistance of the Aluminide Coating Formed on Carbon Steels

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An Approximate Numerical methods for mathematical and Physical Studies for Covid-19 models

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Computer Systems Science & Engineering 2022年第9期42卷 1147-1163页

作者： hammad Alotaibi Khaled A.Gepreel mohamed S.mohamed Amr m.S.mahdy Department of mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia

The advancement in numerical models of serious resistant illnesses is a key research territory in different fields including the nature and the study of disease *** of the aims of these models is to comprehend the elements of conduction of these *** the new strain of Covid-19(Coronavirus),there has been no immunization to protect individuals from the virus and to forestall its spread so *** things being equal,control procedures related to medical services,for example,social distancing or separation,isolation,and travel limitations can be adjusted to control this *** article reveals some insights into the dynamic practices of nonlinear Coronavirus models dependent on the homotopy annoyance strategy(HPm).We summon a novel sign stream chart that is utilized to depict the Coronavirus *** the numerical investigations,it is uncovered that social separation of the possibly tainted people who might be conveying the infection and the healthy virus-free people can diminish or interrupt the spread of the *** mathematical simulation results are highly concurrent with the statistical *** free balance and dependability focus for the Coronavirus model is discussed and the presence of a consistently steady arrangement is demonstrated.

关键词： Covid-19 model optimal control existence of uniformly stable signal stream chart homotopy perturbation technique

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Dynamical Behaviors of Nonlinear Coronavirus (COVID-19) model with Numerical Studies

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Computers, materials & Continua 2021年第4期67卷 675-686页

作者： Khaled A.Gepreel mohamed S.mohamed hammad Alotaibi Amr m.S.mahdy Department of mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia Department of mathematics Zagazig UniversityZagazig44519Egypt Department of mathematics Al-Azher UniversityNasr City11884Egypt

The development of mathematical modeling of infectious diseases is a key research area in various elds including ecology and *** aim of these models is to understand the dynamics of behavior in infectious *** the new strain of coronavirus(COVID-19),there is no vaccine to protect people and to prevent its spread so ***,control strategies associated with health care,such as social distancing,quarantine,travel restrictions,can be adopted to control the pandemic of *** article sheds light on the dynamical behaviors of nonlinear COVID-19 models based on two methods:the homotopy perturbation method(HPm)and the modied reduced differential transform method(mRDTm).We invoke a novel signal ow graph that is used to describe the COVID-19 *** our mathematical studies,it is revealed that social distancing between potentially infected individuals who are carrying the virus and healthy individuals can decrease or interrupt the spread of the *** numerical simulation results are in reasonable agreement with the study *** free equilibrium and stability point for the COVID-19 model are ***,the existence of a uniformly stable solution is proved.

关键词： Nonlinear COVID-19 model equilibrium point stability existence of uniformly stable signal ow graph homotopy perturbation method reduced differential transform method

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Analysis and Characterization of Pore System and Grain Sizes of Carbonate Rocks from Southern Lebanon

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Journal of Earth Science 2023年第1期34卷 101-121页

作者： mohamed K.Salah hammad Tariq Janjuhah Josep Sanjuan Department of Geology American University of BeirutRiad El SolhBeirut11072020Lebanon Department of Geology Shaheed Benazir Bhutto UniversitySheringal KP10850Pakistan Department of Earth and Ocean Dynamics Faculty of Earth SciencesUniversity of BarcelonaBarcelona08028Spain

Carbonate rocks are common in many parts of the world, including the Eastern mediterranean, where they host significant groundwater supplies and are widely used as building and ornamental stones. The porosity of carbonate rocks plays a critical role in fluid storage and retrieval. The pore structure connectivity, in particular, controls many properties of geological formations, as well as the relationships between the properties of individual minerals and the bulk properties of the rock. To study the relationships between porosity, rock properties, pore structure, pore size, and their impact on reservoir characteristics, 46 carbonate rock samples were collected from four stratigraphic sections exposed near Sidon, South Lebanon. The studied carbonate rocks are related to marine deposits of different ages(e.g., Upper Cretaceous, Eocene, and Upper miocene). In order to understand the pore connectivity, the mICP(mercury injection capillary pressure) technique was conducted on ten representative samples. Results from the SEm analysis indicate the dominance of very fine and fine pore sizes, with various categories ranging in diameter from 0.1 to10 μm. The mICP data revealed that the pore throat radii vary widely from 0.001 to 1.4 μm, and that all samples are dominated by micropore throats. The grain size analysis indicated that the studied rocks have significant amounts of silt-and clay-size grains with respect to the coarser ‘sand-size’ particles, suggesting a high proportion of microporosity. Obtained results, such as the poorly-sorted nature of grains, high microporosity, and the high percentage of micropore throats, justify the observed low mean hydraulic radius, the high entry pressure, and the very low permeability of the studied samples. These results suggest that the carbonate rocks near Sidon(south of Lebanon) are possibly classified as non-reservoir facies.

关键词： petrophysics mercury injection capillary pressure(mICP) micrite microtexture microporosity platform carbonates southern Lebanon

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Tungsten incorporated mobil-type eleven zeolite membranes: Facile synthesis and tuneable wettability for highly efficient separation of oil/water mixtures

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Chinese Journal of Chemical Engineering 2023年第8期60卷 242-252页

作者： hammad Saulat Jianhua Yang Tao Yan Waseem Raza Wensen Song Gaohong He State Key Laboratory of Fine Chemicals Institute of Adsorption and Inorganic MembraneDalian University of TechnologyDalian 116024China Panjin Institute of Industrial Technology Dalian University of TechnologyPanjin 124221China Institute of Advance Study Shenzhen UniversityShenzhen 518060China

Tungsten (W) incorporated mobil-type eleven (mEL) zeolite membrane (referred to as W-mEL membrane) with high separation performance was firstly explored for the separation of oil/water mixtures under the influence of gravity.W-mEL membranes were grown on stainless steel (SS) meshes through in-situ hydrothermal growth method facilitated with (3-aminopropyl)triethoxysilane (APTES) modification of stainless steel meshes,which promote the heterogeneous nucleation and crystal growth of W-mEL zeolites onto the mesh surface.W-mEL membranes were grown on different mesh size supports to investigate the effect of mesh size on the separation performance of the *** assynthesized W-mEL membrane supported on 500 mesh (25μm)(W-mEL-500) exhibit the hydrophilic nature with a water contact angle of 11.8°and delivers the best hexane/water mixture separation with a water flux and separation efficiency of 46247 L·m^(-2)·h^(-1)and 99.5%,*** wettability of W-mEL membranes was manipulated from hydrophilic to hydrophobic nature by chemically modifying with the fluorine-free compounds (hexadecyltrimethoxysilane (HDTmS) and dodecyltrimethoxysilane(DDTmS)) to achieve efficient oil-permselective separation of heavy oils from *** the hydrophobically modified W-mEL membranes,W-mEL-500-HDTmS having a water contact angle of146.4°delivers the best separation performance for dichloromethane/water mixtures with a constant oil flux and separation efficiency of 61490 L·m^(-2)·h^(-1)and 99.2%,respectively along with the stability tested up to 20 *** W-mEL-500-HDTmS and W-mEL-500-DDTmS membranes also exhibit similar separation performances for the separation of heavy oil from sea water along with a 20-fold lower corrosion rate in comparison with the bare stainless-steel mesh,indicating their excellent stability in *** to the reported zeolite membranes for oil/water separation,the as-synthesized and hydrophobically modified W-mEL membranes shows competiti

关键词： Corrosion Dodecyltrimethoxysilane Hexadecyltrimethoxysilane membranes Oil/water separation Zeolite

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