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Comparative Study between Microscopic and Endoscopic Trans-Sphenoidal Surgery for Growth Hormone-Secreting Pituitary Adenomas with Super-Sellar Extension

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Open Journal of Modern Neurosurgery 2020年第4期10卷 393-402页

作者： Ahmed Sabry abdelkader ibrahim abdel fattah Abou Alfotoh Shehab Mohammad Fathy Eissa Neurosurgery Department Nasr City Hospital of Health Insurance Cairo Egypt Neurosurgery Department Faculty of Medicine Al-Azhar University Cairo Egypt

Background: Advances in the era of modern micro-neurosurgery enabled a reduction of surgical invasiveness and brain retraction which has been defined as minimally invasive or keyhole surgery. Sinonasal endoscopy has brought radical changes in the concepts of pathophysiology and treatment of sinonasal aliments as well as surgical techniques. Aim of the Study: To compare between the use of endoscopic and microscopic trans-sphenoidal approach in resection of growth hormone-secreting pituitary adenomas with Suprasellar Extension. Patients and Methods: This is a prospective study. it had been conducted upon 20 patients having growth hormone secreting pituitary adenoma admitted to Neurosurgery department in Alzar University hospitals and Nasr City insurance hospital from 2015 to 2018, divided into 2 groups;group A (10 cases) underwent endoscopic endonasal trans-sphenoidal pituitary adenoma resection, while group B (10 cases) operated upon using the standard microscopic trans-sphenoidal pituitary adenoma resection. The inclusion criteria were included: All patients with growth hormone secreting pituitary adenomas showing manifestations of acromegaly, mass effect or hormonal disturbance. Results: This study showed that improvement in outcome was higher in endoscopic group opposed to microscopic group (100% vs. 71% improved headache, 80% vs. 60% visual improvement, 75% vs. 20% fundus improvement and 60% vs. 30% field improvement). Conclusion: We concluded that fully endoscopic procedure result in improved rates of complete tumor removal and a reduced incidence of complications, when compared to the microscopic approach.

关键词： Acromegaly Pituitary Adenomas Endoscopic Trans-Sphenoidal Surgery Microscopic Trans-Sphenoidal Surgery

Behavior of raft on settlement reducing piles:Experimental model study

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Behavior of raft on settlement reducing piles:Experimental m...

Rapid Magnetic 3D Printing of Cellular Structures with MCF-7 Cell inks

第13届全国岩石动力学学术会议

作者： Basuony El-Garhy Ahmed abdel Galil abdel-fattah Youssef Mohamed Abo Raia Civil Engineering Department Faculty of EngineeringMinufiya UniversityShebin El-KomEgypt

An experimental program is conducted on model piled rafts in sand *** experimental program is aimed to investigate the behavior of raft on settlement reducing *** testing program includes tests on models of single pile,unpiled rafts and rafts on 1,4,9,or 16 *** model piles beneath the rafts are closed ended displacement piles installed by *** lengths of piles are used in the experiments to represent slenderness ratio,L/D,of 20,30 and 50,*** dimensions of the model rafts are 30 cm x 30cm with different thickness of 0.5 cm,1.0 cm or 1.5 *** raft-soil stiffness ratios of the model rafts ranging from 0.39 to 10.56 cover flexible to very stiff *** improvement in the ultimate bearing capacity is represented by the load improvement ratio,LiR,and the reductions in average settlement and differential settlement are represented by the settlement ratio,SR,and the differential settlement ratio,DSR,*** effects of the number of settlement reducing piles,raft relative stiffness,and the slenderness ratio of piles on the load improvement ratio,settlement ratio and differential settlement ratio are presented and *** results of the tests show the effectiveness of using piles as settlement reduction measure with the *** the number of settlement reducing piles increases,the load improvement ratio increases and the differential settlement ratio decreases.

关键词： Raft Settlement reducing piles Piled raft Model tests Sand soil

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Research 2019年第1期2019卷 1183-1195页

作者： S.Mishriki A.R.abdel fattah T.Kammann R.P.Sahu F.Geng i.K.Puri School of Biomedical Engineering McMaster UniversityHamiltonOntarioCanada Department of Mechanical Engineering McMaster UniversityHamiltonOntarioCanada Faculty of Biological Sciences Friedrich-Schiller-University JenaGermany

A contactless label-free method using a diamagnetophoretic ink to rapidly print three-dimensional(3D)scafold-free multicellular structures is *** inks consist of MCF-7 cells that are suspended in a culture medium to which a paramagnetic salt,diethylenetriaminepentaacetic acid gadolinium(iii)dihydrogen salt hydrate(Gd-DTPA),is *** a magnetic feld is applied,the host fuid containing the paramagnetic salt is attracted towards regions of high magnetic feld gradient,displacing the ink towards regions with a low *** this method,3D structures are printed on ultra-low attachment(ULA)*** a tissue culture treated(TCT)surface,a 3D printed spheroid coexists with a two-dimensional(2D)cell monolayer,where the composite is termed as a 2.5D *** 3D structures can be magnetically printed within 6 hours in a medium containing 25 mM *** infuence of the paramagnetic salt on MCF-7 cell viability,cell morphology,and ability of cells to adhere to each other to stabilize the printed structures on both ULA and TCT surfaces is *** expressions of hypoxia-inducible factor 1-alpha(HiF1�)and vascular endothelial growth factor(VEGF)allow comparison of the relative stresses for the printed 3D and 2.5D cell geometries with those for 3D spheroids formed without magnetic *** magnetic printing method can be potentially scaled to a higher throughput to rapidly print cells into 3D heterogeneous cell structures with variable geometries with repeatable dimensions for applications such as tissue engineering and tumour formation for drug discovery.

关键词： structure culture dimensions

Serum Level of Thyroid Hormones in Patients with Chronic Hepatitis C Virus infection

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Open Journal of Endocrine and Metabolic Diseases 2016年第3期6卷 126-134页

作者： Mohamed abdel-fattah El-Feki Nilly Helmy Abdalla Mohamed ibrahim Atta Ahmed Amin ibrahim internal Medicine Department Faculty of Medicine Beni Suef University Beni Suef Egypt

Objective: There are clinical and laboratory associations between thyroid and liver diseases. Hepatitis C virus (HCV) is known to be responsible for both hepatic and extrahepatic diseases. The most frequent and clinically important endocrine extrahepatic diseases are thyroid disorders and type 2 diabetes mellitus. We aim to study the relationship between the serum level of thyroid hormones (THs) and the severity of liver disease in patients with chronic hepatitis C virus (CHC) infection. Methods: 60 patients with CHC infection were selected for the study. They were divided into two groups: with or without liver cirrhosis. Those with liver cirrhosis were further subdivided according to the Child-Turcotte-Pugh scoring system. Serum levels of free T3 (FT3), free T4 (FT4) and TSH were measured to all patients. Results: There was decrease in the FT3 and FT4 levels and increase in the TSH levels in patients with CHC with cirrhosis when compared to patients with CHC without cirrhosis. Conclusion: Thyroid profile abnormalities were seen in cirrhotic HCV patients when compared to non-cirrhotic patients. The abnormalities in the serum level of THs (decreased FT3, FT4, and increased TSH) are strongly associated with the severity of liver damage and advancing of the child score.

关键词： Hepatitis C Virus Thyroid Hormones Liver Cirrhosis

Recovery of oil and free fatty acids from spent bleaching earth using sub-critical water technology supported with kinetic and thermodynamic study

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Advances in Bioscience and Biotechnology 2014年第3期5卷 261-272页

作者： Rehab abdel fattah N. A. Mostafa Mohamed S. Mahmoud Wael abdelmoez Chemical Engineering Ddepartment Minia University Minia Egypt Faculty of Aapplied Mmedical Sscience Taif Uni-versity Taif KSA

This work represents the extraction of oil with high free fatty acid content from spent bleaching earth using sub-critical water technology as a greener production pathway. The extraction efficiencies under different conditions were investigated. The studied parameters include temperatures in the range of 180 to 270°C, the feed to solventfeed-to-solvent (in this case water) ratio (1:1, 1:2, 1:3, 1:4 and 1:5) and extraction times in the range of 5-60 minutes. The results showed that the optimum temperature, feed to solventfeed-to-solvent ratio, and extraction time were 270°C, 1:3, and 20 minutes, respectively. in another experiment, the extracted free fatty acids were converted into mono-, di-, and triglycerides through esterification with glycerol to increase the value added of the extracted products. The kinetics of the extraction process was found to be corresponding to an irreversible consecutive unimolecular-type first order reaction, consisting of the extraction step followed by the decomposition reaction step. Both reaction rates of extraction and decomposition were estimated using the reaction rate equations utilizing the nonlinear regression method. The apparent activation energy was calculated to be 46.1 kJ·mol-1. This result indicates a diffusion controlled reaction. For more exploration and deep understanding of the extraction mechanism, other thermodynamic parameters were also calculated and analyzed including,ΔH#, ΔS#, and ΔG# of the extraction step.

关键词： Spent Bleaching Earth Sub-Critical Water Technology Kinetics of Extraction Thermodynamic Parameters

A Reconfigurable UWB Bandpass Filters with Embedded Multi-Mode Resonators

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Open Journal of Antennas and Propagation 2018年第3期6卷 43-59页

作者： Eman Gamal Ouf Ashraf S. Mohra Esmat abdel-fattah Abdallah Hadia Elhennawy Electronics Research institute Giza Egypt Faculty of Engineering Ain Shams University Cairo Egypt Benha Faculty of Engineering Benha University Benha Egypt

The two proposed filters described here satisfy the Federal Communications Commission Ultra-wideband (FCC-UWB) specifications and also control the center frequency and bandwidth of the filters passband. These filters consist of two distinguishing parts, Electromagnetic bandgap (EBG)-embedded multiple- mode resonator (MMR) and interdigital coupled lines to realize high performance in the operation band with a compact size of 14.0 mm × 10.1 mm. The main advantage of the two proposed filters is that three different bands are tuned. The 1st tuned band is from 3.5 GHz to 11.4 GHz for the first filter and from 3.1 GHz to 11.6 GHz for the second proposed filter, respectively. The 2nd tuned band is from 3.5 GHz to 7.5 GHz for the first filter and from 3.1 GHz to 7.8 GHz for the second proposed filter, respectively. While the 3rd tuned band of the first proposed filter is from 3.5 GHz to 5.9 GHz and from 3.1 GHz to 5.8 GHz for the second proposed filter. The bandwidth of the filters can be changed by increasing the length of the outer open circuited stubs which are controlled by using switching matrix equipment (mini circuit, replacement of PiN diodes). To validate the design theory, a reconfigurable UWB bandpass filters (BPFs) with EBG Embedded MMR are designed, fabricated and measured. Good agreement is found between simulated and measured results.

关键词： UWB Bandpass Filter EBG MMR Reconfigurable Stubs

Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients

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World Journal of Hepatology 2016年第32期8卷 1392-1401页

作者： Mahmoud Khattab Mohamed Amin Sakr Mohamed abdel fattah Youssef Mousa Elwy Soliman Ashraf Breedy Mona Fathi Salwa Gaber Ahmed Altaweil Ashraf Osman Ahmed Hassouna ibrahim Motawea Department of internal Medicine Minia University Department of Tropical Medicine Ain Shams University Department of Clinical Pathology Ain Shams University Department of Pathology Minia University Department of Pathology Ain Shams University Department of Clinical Pathology Minia University Department of Cardiothoracic Surgery Ain Shams University

AiMTo investigate the diagnostic ability of a non-invasive biological marker to predict liver fibrosis in hepatitis C genotype 4 patients with high accuracy. METHODSA cohort of 332 patients infected with hepatitis C genotype 4 was included in this cross-sectional study. Fasting plasma glucose, insulin, C-peptide, and angiotensin-converting enzyme serum levels were measured. insulin resistance was mathematically calculated using the homeostasis model of insulin resistance (HOMA-iR). RESULTSFibrosis stages were distributed based on Metavir score as follows: F0 = 43, F1 = 136, F2 = 64, F3 = 45 and F4 = 44. Statistical analysis relied upon reclassification of fibrosis stages into mild fibrosis (F0-F) = 179, moderate fibrosis (F2) = 64, and advanced fibrosis (F3-F4) = 89. Univariate analysis indicated that age, log aspartate amino transaminase, log HOMA-iR and log platelet count were independent predictors of liver fibrosis stage (P CONCLUSiONOur predictive model is easily available and reproducible, and predicted liver fibrosis with acceptable accuracy.

关键词： Liver fibrosis insulin resistance Aspartate amino transaminase Platelets Age

Focusing limits of intense ultrafast laser pulses in a high pressure gas: road to new spectroscopic source

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Focusing limits of intense ultrafast laser pulses in a high ...

Community-based screening for pre-hypertension among military active duty personnel

CCAST“2002年全国强场激光物理”研讨会

作者： A.Talebpour M.abdel-fattah S.L.Chin Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4 Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4 Centre’ Optique Photonique et Laser （COPL） and Dept de Physique Universit Laual Qubec Qc. Canada GIK 7P4

＜正＞ As a result of focusing ultrafast Ti:Sapphire laser pulses in a gas. a plasma column is created. its density does not exceed some limiting value as a result of the defocusing by the electrons resulting from muluphoton ionization and the involvement of high order nonlinearities. The spectrum of the radiation from the excited species in the column has little contribution from the plasma continuum and the line broadening is less than that of the spectra radiated from a plasma generated by a long laser pulse. Thus. the spectroscopic source obtained using short laser pulses is an excellent source for spectroscopy, （?）2000 Published by Elsevier Science B.V.

关键词： Propagation: Ti:Sapphire laser pulse Plasma: Spectroscopy Photo-emission spectrum

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海南医学院学报 2009年第2期15卷 122-127页

作者： Moataz M.abdel-fattah Fayssal M.Farahat Abdul-Salam A.Al-Shehri Department of Preventive Medicine(Research and Epidemiology Unit) Department of Family Medicine Al-Hada Armed Forces HospitalTaif

Objective: The purpose of this study to determine the prevalence of both pre-hypertension and hypertension and risk factors associated with newly diagnosed Saudi military active duty service ***: Community-based screening of 1283 Saudi military active duty service personnel was conducted during the period September-December 2007 at six randomly selected out of a total of 15 military units of Taif region,Western of Saudi *** tools included self-administrated questionnaire,general physical examination,anthropometric measurements and assessment of blood ***: All participants were Saudi *** age ranged from 19-56 years old with mean ± SD of 37.2 ± *** applying the Joint National Committee on prevention,detection,evaluation,and treatment of high hypertension(JNC-7) criteria,214(17.3%) were considered *** logistic regression analysis showed that obesity as measured by body mass index(OR=2.71 Ci: 1.39-5.28),positive family history(OR=1.46 Ci:1.03-2.06),ever smoking(OR=1.45 Ci:1.05-2.02),and increased waist circumference(OR=1.04 Ci:1.02-1.06) were the significant predictors of workplace newly diagnosed hypertension among military active duty ***: Pre-hypertension is a common hidden problem and it predicts the development of frank *** of the current study support the recommendation of lifestyle modification for pre-hypertension ***,further prospective studied are required to determine the role of pharmacotherapy in pre-hypertension.

关键词：高血压军队建设疾病患者军事人员