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Haplotypes at the 5′-Flanking Region of Peroxisome Proliferator-Activated Receptor γ Gene and Their Association with the Growth and Body Composition Traits in Chickens

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Agricultural Sciences in China 2011年第2期10卷 296-303页

作者： han qing wang Shou-zhi HU Guo LI Hui College of Animal Science and Technology Northeast Agricultural UniversityHarbin 150030P.R.China

Peroxisome proliferator-activated receptor g（PPARg） is an important regulator of chicken preadipocyte proliferation and *** this study,polymorphisms were detected by DNA sequencing,PCR-RFLP and some other methods and three polymorphisms（g.-1784_-1768del17,c.-1241GA and c.-75GA） were found in the 5＇ flanking region of PPARg *** and body composition traits were measured in the 8th-10th generation populations of the Northeast Agricultural University broiler lines were divergently selected for abdominal fat *** among individuals were screened in the above *** haplotype-based association analysis on growth and body composition traits was carried *** association analysis showed that haplotypes based on three polymorphisms at 5＇ flanking region of PPARg gene were significantly associated with abdominal fat weight（AFW）,abdominal fat percentage（AFP,AFW/BW7）,liver weight（LW）,liver weight percentage（LFP,LW/BW7）,shank length（ShL）,femur weight（FeW）,keel length（KeL）,and metatarsus circle（MeC）（P0.05） and suggestive significantly associated with pectoralis major weight（PMaW）,pectoralis minor weight（PMiW）,pectoralis minor weight percentage（PMiWP,PMiW/BW7）,and metatarsus length（MeL）（P0.2）.The least square analysis showed that the birds with BGA haplotype had significantly higher AFW and AFP than the birds with other haplotypes（P0.05）.The birds with AAG haplotype had significantly higher LW and LW/BW than the birds with other haplotypes（P0.05）.The birds with AAG haplotype had significantly higher PMiW and PMiW/BW than the birds with other haplotypes（P0.05）.The birds with AAG haplotype had significantly higher ShL,FeW,MeL,MeC and KeL than the birds with AGG haplotypes（P0.05）.The results in this study revealed that QTL affecting fatness traits may exist in 5＇ flanking region of PPARg gene in chickens and PPARg gene might be one of the genes having important influences on the growth and bone traits in chickens.

关键词： chicken PPARg haplotype fatness bone major gene

Poly(ethylene oxide) Solubilization in Reverse Microemulsion:Conductivity and UV-Vis Spectra Studies

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Chinese Chemical Letters 2000年第8期11卷 735-738页

作者： Zhen Shan HOU Zhi Ping LI han qing wang Xinjiang Institute of Chemistry The Chinese Academy of sciencesUrumqi 830011 Lanzhou Institute of Chemical Physics The Chinese Academy of sciencesLanzhou730000

The effect of poly (ethylene oxide) (PEO) on the w/o microemulsion is studied. The addition of PEO induces a decrease of attractive interaction between droplets in reverse microemulsion. Due to the absence of interaction between cationic surfactant and neutral polymer, the polymer molecules are forced into the interior of water core, avoiding the interfacial region.

关键词： reverse microemulsion cationic surfactant electrical percalation PEO

Rice roots avoid asymmetric heavy metal and salinity stress via an RBOH-ROS-auxin signaling cascade

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Molecular Plant 2023年第10期16卷 1678-1694页

作者： han-qing wang Xing-Yu Zhao Wei Xuan Peng wang Fang-Jie Zhao State Key Laboratory of Crop Genetics&Germplasm Enhancement and Utilization College of Resources and Environmental SciencesNanjing Agricultural UniversityNanjing 210095China

Root developmental plasticity is crucial for plants to adapt to a changing soil environment,where nutrients and abiotic stress factors are distributed *** plant roots sense and avoid heterogeneous abiotic stress in soil remains ***,we show that,in response to asymmetric stress of heavy metals(cadmium,copper,or lead)and salt,rice roots rapidly proliferate lateral roots(LRs)in the stress-free area,thereby remodeling root architecture to avoid localized *** and quantitative analyses of reactive oxygen species(ROS)showed that asymmetric stress induces a ROS burst in the tips of the exposed roots and simultaneously triggers rapid systemic ROS signaling to the unexposed *** of a ROS scavenger to either the stressed or stress-free area abolished systemic ROS signaling and LR proliferation induced by asymmetric *** stress also enhanced cytosolic calcium(Ca^(2+))signaling;blocking Ca^(2+)signaling inhibited systemic ROS propagation and LR branching in the stress-free *** identified two plasma-membrane-localized respiratory burst oxidase homologs,OsRBOHA and OsRBOHI,as key players in systemic ROS signaling under asymmetric *** of OsRBOHA and OsRBOHI in roots was upregulated by Cd stress,and knockout of either gene reduced systemic ROS signaling and LR proliferation under asymmetric ***,we demonstrated that auxin signaling and cell wall remodeling act downstream of the systemic ROS signaling to promote LR ***,our study reveals an RBOH-ROS-auxin signaling cascade that enables rice roots to avoid localized stress of heavy metals and salt and provides new insight into root system plasticity in heterogenous soil.

关键词： root system architecture heterogenous abiotic stress reactive oxygen species signaling

Molecular mechanisms underlying the toxicity and detoxification of trace metals and metalloids in plants

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Journal of Integrative Plant Biology 2023年第2期65卷 570-593页

作者： Zhong Tang han-qing wang Jie Chen Jia-Dong Chang Fang-Jie Zhao State Key Laboratory of Crop Genetics and Germplasm Enhancement College of Resources and Environmental SciencesNanjing Agricultural UniversityNanjing 210095China

Plants take up a wide range of trace metals/metalloids(hereinafter referred to as trace metals)from the soil,some of which are essential but become toxic at high concentrations(e.g.,Cu,Zn,Ni,Co),while others are non-essential and toxic even at relatively low concentrations(e.g.,As,Cd,Cr,Pb,and Hg).Soil contamination of trace metals is an increasing problem worldwide due to intensifying human *** metal contamination can cause toxicity and growth inhibition in plants,as well as accumulation in the edible parts to levels that threatens food safety and human *** the mechanisms of trace metal toxicity and how plants respond to trace metal stress is important for improving plant growth and food safety in contaminated *** accumulation of excess trace metals in plants can cause oxidative stress,genotoxicity,programmed cell death,and disturbance in multiple physiological *** have evolved various strategies to detoxify trace metals through cell-wall binding,complexation,vacuolar sequestration,efflux,and *** signal transduction pathways and regulatory responses are involved in plants challenged with trace metal *** this review,we discuss the recent progress in understanding the molecular mechanisms involved in trace metal toxicity,detoxification,and regulation,as well as strategies to enhance plant resistance to trace metal stresses and reduce toxic metal accumulation in food crops.

关键词： detoxification food safety stress response trace metals/metalloids toxic mechanisms

New Sesquiterpenoids from Hedychium yunnanense gagnep

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Chinese Chemical Letters 2000年第11期11卷 1009-1012页

作者： Xiu Hua LIU Dong Bao ZHAO Chong Ren YANG han qing wang Chemistry and Chemical Engineering College of Henan University Kaifeng 475001 Phytochemistry Laboratory Kunming Instute of BotanyC.A.S.Kunming 650204 Lanzhou Institute of Chemical Physics C.A.SLanzhou 730000

Two new sesquiterpenoid trialcohol isomers named 1 beta, 4 alpha 11 alpha -trihydroxyeudesmane (1) and Yunnanensehedychetriol (2), were isolated from the fresh rhizomes of Hedychium Yunnanense gagnep. Their structures... 详细信息

关键词： Hedychium yunnanene Zingiberaceae sesquiterpenoid trialcohol isomers 1 beta,4 alpha,11 alpha-trihydroxyeudesmane Yunnanensehedychetriol

A New Ecdysteroid from Rhaponticum uniflorum

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Chinese Chemical Letters 2001年第9期12卷 797-798页

作者： Yong Hong ZhanG Xin Pu LI Zhi Gang LU han qing wang Lanzhou Institute of Chemical Physics Chinese Academy of SciencesLanzhou 730000 Lanzhou Institute of Animal Science and Animal Medicine Lanzhou 730050

A new phytoecdysteroid was isolated from the root of Rhaponticum uniflorum. Its structure has been shown to be 2, 3, 20, 22-diacetonide ajugasterone.

关键词： Rhaponticum uniflorum compositae 2, 3, 20, 22-diacetonide ajugasterone

Two Novel Poly-Oxygen Bipyridine Alkaloids from Speranskia tuberculata

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Chinese Chemical Letters 2000年第3期11卷 225-228页

作者： Jian Gong SHI han qing wang Min wang Guang Xiong ZHOU Yong Chun YANG Wen Yan HU Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050 Lanzhou Institute of Chemical Physics Chinese Academy of SciencesLanzhou 730000

Two novel poly-oxygen bipyridine alkaloids, speranculatines A (1) and B (2) have been isolated from Speranskia tuberculata. Their structures were elucidated by spectroscopic methods including 2D NMR techniques and X-r... 详细信息

关键词： Speranskia tuberculata Euphorbiaceae speranculatines A and B

Machine learning for carbonate formation drilling: Mud loss prediction using seismic attributes and mud loss records

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Petroleum Science 2024年第2期21卷 1241-1256页

作者： Hui-Wen Pang han-qing wang Yi-Tian Xiao Yan Jin Yun-Hu Lu Yong-Dong Fan Zhen Nie National Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing102249China College of Science China University of Petroleum-BeijingBeijing102249China Petroleum Exploration and Production Research Institute SINOPECBeijing102206China College of Petroleum Engineering China University of Petroleum-BeijingBeijing102249China Research Institute of Petroleum Exploration and Development CNPCBeijing100083China

Due to the complexity and variability of carbonate formation leakage zones, lost circulation prediction and control is one of the major challenges of carbonate drilling. It raises well-control risks and production expenses. This research utilizes the H oilfield as an example, employs seismic features to analyze mud loss prediction, and produces a complete set of pre-drilling mud loss prediction solutions. Firstly, 16seismic attributes are calculated based on the post-stack seismic data, and the mud loss rate per unit footage is specified. The sample set is constructed by extracting each attribute from the seismic trace surrounding 15 typical wells, with a ratio of 8:2 between the training set and the test set. With the calibration results for mud loss rate per unit footage, the nonlinear mapping relationship between seismic attributes and mud loss rate per unit size is established using the mixed density network ***, the influence of the number of sub-Gausses and the uncertainty coefficient on the model's prediction is evaluated. Finally, the model is used in conjunction with downhole drilling conditions to assess the risk of mud loss in various layers and along the wellbore trajectory. The study demonstrates that the mean relative errors of the model for training data and test data are 6.9% and 7.5%, respectively, and that R2is 90% and 88%, respectively, for training data and test data. The accuracy and efficacy of mud loss prediction may be greatly enhanced by combining 16 seismic attributes with the mud loss rate per unit footage and applying machine learning methods. The mud loss prediction model based on the MDN model can not only predict the mud loss rate but also objectively evaluate the prediction based on the quality of the data and the model.

关键词： Lost circulation Risk prediction Machine learning Seismic attributes Mud loss records

A New Nortriterpenoid Glycoside from Sinofranchetia chinensis

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Chinese Chemical Letters 2001年第1期12卷 55-58页

作者： Xiao Hui YANG Rui Jun MA Run Hua LU Xiao Ning WEI Yun Pu wang han qing wang Jie KONG Department of Biology Northwest Normal UniversityLanzhou 730070 United Laboratory ofTibetanMedicines andNaturalMedicines Lanzhou Institute of Chemical Physics Chinese Academy of SciencesChee Zheng Tibetan Medicines GroupLanzhou 730000 Department of Chemistry NorthwestNormal UniversityLanzhou 730070

A new 30-nortriterpenoid glycopside, 3-O-a-L-arabinopyranosyl-30-norhederagenin 28-O-a-L-rhamnopyranosyl(1-->4)-beta -D-glucopyranosyl (1-->6)-beta -D-glucopyranoside 1, named sinofoside A was isolated from Sinofranchetia chinensis. Its structure was elucidadated by spectra FAB-MS, 2D-NMR including H-1-H-1 COSY, H-1-C-13 COSY, TOSCY, HMBC and NOESY techniques.

关键词： Sinofranchetia chinensis nortriterpenoid glycopside sinofoside A 2D-NMR