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基于景观生态风险和生态系统服务价值的海岸带地区生态修复分区研究——以防城港市为例

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环境工程技术学报 2024年第3期14卷 1066-1076页

作者：沈杨汪晗聂鑫广西大学公共管理学院

以防城港市海岸带地区为例,计算其在不同时期内的景观生态风险和生态系统服务价值,利用空间自相关分析二者的空间关联性,基于分析结果划定海岸带地区的国土空间生态修复分区。结果表明:2000—2020年防城港市海岸带地区的土地利用类型以... 详细信息

以防城港市海岸带地区为例,计算其在不同时期内的景观生态风险和生态系统服务价值,利用空间自相关分析二者的空间关联性,基于分析结果划定海岸带地区的国土空间生态修复分区。结果表明:2000—2020年防城港市海岸带地区的土地利用类型以林地为主,约占研究区面积的50%,其次为海域(18%)、耕地(16%)和建设用地(6%),在研究期间海岸带地区林地、海域和建设用地的类型转换最为剧烈。研究区整体生态风险等级以较低生态风险为主,约占研究区面积的32%,其次为中生态风险(26%)、低生态风险(18%)和较高生态风险(16%),而高生态风险的面积较少,约占研究区面积的8%,研究期间较低生态风险和中生态风险的范围呈现缩减趋势,而低生态风险、较高生态风险和高生态风险的范围呈现扩张趋势。研究区的生态系统服务价值呈现先增后减的趋势,20年间累计减少5.43亿元。基于景观生态风险和生态系统服务价值的空间集聚分析结果,将研究区划分为生态优先修复区、生态重点修复区、生态综合提升区、生态预防治理区和生态保育涵养区,针对不同分区分别提出了滨海湿地修复、农地肥力培育、城市内河治理、提升生态用地完整度和促进林草自然更新等生态修复措施。

关键词：景观生态风险生态系统服务价值生态修复分区海岸带防城港市

Large area van der Waals epitaxy of II-VI CdSe thin films for flexible optoelectronics and full-color imaging

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Nano Research 2022年第1期15卷 368-376页

作者： Wenwu Pan Junliang Liu Zekai Zhang Renjie Gu Alexandra Suvorova Sarah Gain han wang Ziyuan Li Lan Fu Lorenzo Faraone Wen Lei Department of Electrical Electronic and Computer EngineeringThe University of Western Australia35 Stirling HighwayCrawley 6009Australia Centre for Microscopy Characterisation and AnalysisThe University of Western Australia35 Stirling HighwayPerth 6009Australia Department of Electronic Materials Engineering Research School of PhysicsThe Australian National UniversityCanberra ACT 2601Australia

The demand for future semiconductor devices with enhanced performance and lower cost has driven the development of epitaxial growth of high quality,free-standing semiconductor thin film materials without the requirement of lattice matching to the substrate,as well as their transfer to other substrates and associated device processing technology.This work presents a study on the van der Waals epitaxy based molecular beam epitaxy of CdSe thin films on two-dimensional layered mica substrates,as well as related etch-free layer transfer technology of large area,free-standing layers and their application in flexible photodetectors for full-color imaging.The photoconductor detectors based on these flexible CdSe thin films demonstrate excellent device performance at room temperature in terms of responsivity(0.2 A·W^(-1))and detectivity(1.5×10^(12)Jones),leading to excellent full-color imaging quality in the visible spectral range.An etch-free and damage-free layer transfer method has been developed for transferring these CdSe thin films from mica to other substrate for further device processing and integration.These results demonstrate the feasibility of van der Waals epitaxy method for growing high quality,large area,and free-standing epitaxial layers without the requirement for lattice matching to substrate for applications in low-cost flexible and/or monolithic integrated optoelectronic devices.

关键词： CdSe flexible devices van der Waals epitaxy molecular beam epitaxy layer lift-off

Downregulation of the circadian clock gene period 2 aggravates prognosis in breast cancer patients with obesity

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Oncology and Translational Medicine 2024年第2期10卷 73-78页

作者： Ru-Xing Wu Dan Hu han-wang Zhang Xiao-Yuan Huang Liang Zhuang Reproductive Medicine Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Cancer Biology Research Centre Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Cancer Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Background:Obese individuals diagnosed with breast cancer often experience a less favorable prognosis;however,the underlying mechanisms linking obesity to breast cancer outcomes remain elusive.This study aimed to identify and validate novel prognostic markers associated with breast cancer in patients with obesity.Methods:We conducted a reanalysis of gene expression profiles from normal-weight,overweight,and obese breast cancer patients to identify candidate genes.Subsequently,we validated the protein levels of these candidates using immunohistochemistry.Finally,we investigated the association between candidate genes and breast cancer prognosis at Tongji Hospital,utilizing data from an 8-year follow-up through the Kaplan-Meier method and univariate and multivariate Cox regression models.Results:The fold change of the circadian clock gene period 2(PER2),which exhibited a declining trend with increasing body mass index,was 0.76 in obese patients compared with normal-weight patients.The expression rates of PER2 protein were 44.7%,51.5%,and 61.3%in normal-weight,overweight,and obese patients,respectively.The 8-year recurrence-free survival rates were 75.9%,69.6%,and 64.1%,whereas the 8-year overall survival rates were 86.8%,83.0%,and 76.1%in normal-weight,overweight,and obese patients,respectively(P<0.05).Furthermore,the 8-year recurrence-free survival rates were 66.2%and 76.4%,and the 8-year overall survival rates were 79.9%and 86.3%in the low and high PER2 expression groups,respectively(P<0.05).The unadjusted hazard ratio for PER2 was 1.550(95%confidence interval,1.029–2.335),and the adjusted hazard ratio was 3.003(95%confidence interval,1.838–4.907).Conclusions:Our findings indicate that low PER2 expression serves as an independent risk factor for breast cancer prognosis and may contribute to the unfavorable outcomes observed in obese patients.

关键词： Breast cancer Obesity PER2 Prognosis

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高级别胎儿型肺腺癌并头皮转移1例

中国肺癌杂志 2024年第2期27卷 147-151页

作者：德吉央宗边玛措王玺王寒西藏大学医学院拉萨850010 西藏自治区人民医院呼吸与危重症科拉萨850034 北京大学第一医院呼吸与危重症医学科北京100034 西藏自治区人民医院病理科拉萨850034

胎儿型肺腺癌(fetal adenocarcinoma of the lung,FLAC)是一种罕见的肺部肿瘤。FLAC分为低级别FLAC(low-grade FLAC,L-FLAC)和高级别FLAC(high-grade FLAC,H-FLAC),两者在临床病理特征、生物学行为和临床结局方面有所不同。大多数H-FLAC患者是重度吸烟的中年人。本研究描述了1例罕见的非吸烟年轻男性患者,其最初表现为头顶肿块,最终被诊断为H-FLAC。本文旨在增进对FLAC的了解和认识,提高对该疾病的重视,以防止该疾病漏诊与误诊,加强早期识别、精准诊断,从而推进后续的有效治疗、改善预后。

关键词：青年胎儿型肺腺癌头皮肿瘤转移

Emerging low-dimensional materials for mid-infrared detection

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Nano Research 2021年第6期14卷 1863-1877页

作者： Jiangbin Wu Nan wang Xiaodong Yan han wang Ming Hsieh Department of Electrical and Computer Engineering University of Southern CaliforniaLos AngelesCA90089USA Mork Family Department of Chemical Engineering and Material Science University of Southern CaliforniaLos AngelesCA90089USA

Mid-infrared(IR)detectors based on the emerging low-dimensional(two-dimensional and quasi one-dimensional)materials offer unique characteristics including large bandgap tunability,optical polarization sensitivity and integrability with typical silicon process,which are not available in the mid-IR detectors based on traditional compound semiconductors.Here,we review the recent progress in study of mid-IR detectors based on the low-dimensional materials,including black phosphorus,black arsenic phosphorus,tellurene and BaTiS3,from the perspectives of crystal structure,material synthesis,optical properties,and the detector characteristics.The detector gain and detectivity are benchmarked,and the unique properties,such as the polarization sensitivity,are discussed.We also provide our perspective about key future research directions in this field.

关键词： mid-infrared detector anisotropy low-dimensional gain detectivity

Rényi divergence on learning with errors

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Science China(Information Sciences) 2020年第9期63卷 124-139页

作者： Yang TAO han wang Rui ZhanG State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences School of Cyber Security University of Chinese Academy of Sciences

Many lattice-based schemes are built from the hardness of the learning with errors problem, which naturally comes in two flavors: the decision LWE and search LWE. In this paper, we investigate the decision LWE and search LWE by Rényi divergence respectively and obtain the following results: For decision LWE,we apply RD on LWE variants with different error distributions(i.e., center binomial distribution and uniform distribution, which are frequently used in the NIST PQC submissions) and prove the pseudorandomness in theory. As a by-product, we extend the so-called public sampleability property and present an adaptively public sampling property to the application of Rényi divergence on more decision problems. As for search LWE, we improve the classical reduction proof from Gap SVP to LWE. Besides, as an independent interest,we also explore the intrinsic relation between the decision problem and search problem.

关键词： Rényi divergence learning with errors decision problems search problems post-quantum cryptography

2022年医学期刊发表中国影像医学领域指南及共识的科学性、透明性和适用性的评价分析

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中华放射学杂志 2024年第4期58卷 430-436页

作者：吕晗周奇刘军王悍王振常陈耀龙首都医科大学附属北京友谊医院放射科北京100050 兰州大学基础医学院循证医学中心兰州730000 中南大学湘雅二医院放射科长沙410011 上海市第一人民医院放射科上海200080 医学期刊知识挖掘与服务重点实验室北京100052 兰州大学基础医学院循证医学中心中国医学科学院循证评价与指南研究创新单元兰州730000 中华医学会杂志社指南与标准研究中心北京100052

目的使用临床实践指南的科学性(scientificity)、透明性(transparency)和适用性(applicability)评级(rankings)(STAR)工具评价2022年发表的影像医学领域指南及共识的质量。方法在中国知网数据库、万方数据知识服务平台、中国生物医学文... 详细信息

目的使用临床实践指南的科学性(scientificity)、透明性(transparency)和适用性(applicability)评级(rankings)(STAR)工具评价2022年发表的影像医学领域指南及共识的质量。方法在中国知网数据库、万方数据知识服务平台、中国生物医学文献数据库、中华医学期刊网、Medline(PubMed)等数据库检索影像医学领域的指南及共识。检索时间范围自2022年1月1日至12月31日。根据STAR工具进行评分,每部指南或共识均由2位评价人员开展独立评价并交叉核对。结果共纳入65部中/英文指南及共识,包括指南15部、共识50部。部分指南及共识具有鲜明的学科特色,涉及了人工智能技术(4部)、影像学检查临床适用性评价主题(4部)。对于所有指南及共识,评价最高为89.9分,最低为3.6分,M(Q_(1),Q_(3))为25.0(20.8,35.4)分,指南与共识得分差异不具有统计学意义(P=0.383)。得分最高的3个STAR分项目分别为推荐意见(报告率56.0%)、工作组(报告率38.2%)、临床问题(报告率36.7%),最低的3个STAR分项目分别为计划书(报告率9.6%)、注册(报告率10.8%)、共识方法(报告率21.8%)。结论建议影像医学指南及共识制订者加强学习STAR工具等循证医学方法,从而进一步提升影像医学领域指南及共识的质量。

关键词：指南共识影像医学质量控制和改进

A new 2D van der Waals material with air stability and in-plane anisotropy

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Chinese Journal of Structural Chemistry 2023年第7期42卷 9-13页

作者： han wang Jinyang Liu Minjuan Li Yanqiang Li Yang Zhou Wei Liu Junhua Luo Sangen Zhao State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou350002China College of Chemistry and Materials Science Fujian Normal UniversityFuzhou350007China College of Physics and Energy Fujian Normal UniversityFuzhou350117China

1.Text 2D van der Waals materials possess intriguing features[1],especially optically,such as high nonlinear optical responses[2],broadband spectral response[3],and accessible exciton effects[4].Unlike conventional 2D materials with in-plane isotropy,such as graphene and M0S_(2),2D van der Waals materials with in-plane anisotropic possess in-plane low symmetry structure,inducing the in-plane anisotropic physical properties.Meanwhile,they can be easily moved to various substrates without lattice-matching problems.

关键词： properties. plane anisotropic

Neuronal and Non-neuronal Cell Types Displaying Circadian Rhythmicity in the Mammalian Suprachiasmatic Nucleus

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Neuroscience Bulletin 2021年第1期37卷 138-140页

作者： S.K.Tahajjul Taufique han wang Center for Circadian Clocks Soochow UniversitySuzhou 215123China School of Biology and Basic Medical Sciences Medical CollegeSoochow UniversitySuzhou 215123China

Circadian rhythms have a period of~24 h and are manifested in almost all living organisms [1].The discovery of the molecular genetic mechanisms underlying circadian rhythmicity was one of the most exciting and inspiring chapters in the history of biology and won the Nobel Prize in Physiology or Medicine in 2017 [2].Equally exciting and inspiring was the discovery that the hypothalamic suprachiasmatic nucleus (SCN) is involved in orchestrating the daily rhythmic activity of physiology。

关键词： exciting matic