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Comprehensive constraints on fermionic dark matter-quark tensor interactions in direct detection experiments

Chinese Physics C 2024年第12期48卷 37-49页

作者： Jin-han liang Yi Liao Xiao-Dong Ma Hao-Lin Wang Key Laboratory of Atomic and Subatomic Structure and Quantum Control(MOE) Guangdong Basic Research Center of Excellence for Structure and Fundamental Interactions of MatterInstitute of Quantum MatterSouth China Normal UniversityGuangzhou 510006China Guangdong-Hong Kong Joint Laboratory of Quantum Matter Guangdong Provincial Key Laboratory of Nuclear ScienceSouthern Nuclear Science Computing CenterSouth China Normal UniversityGuangzhou 510006China

Effective field theory(EFT)provides a model-independent framework for interpreting the results of dark matter(DM)direct detection *** this study,we demonstrate that the two fermionic DM-quark tensor operators(χiσ^(μν)γ^(5)χ)(qσ_(μν)q)and(χσ_(μν)χ)(qσ_(μν)q)can contribute to the DM electric and magnetic dipole moments via nonperturbative QCD effects,in addition to the well-studied contact DM-nucleon *** then investigate the constraints on these two operators by considering both the contact and dipole contributions using the XENON1T nuclear recoil and Migdal effect *** also recast other existing bounds on the DM dipole operators,derived from electron and nuclear recoil measurements in various direct detection experiments,as constraints on the two tensor *** m_(χ)■1GeV,our results significantly extend the reach of constraints on the DM-quark tensor operators to masses as low as 5MeV,with the bound exceeding that obtained by the Migdal effect with only contact interactions by approximately an order of *** particular,for the operator(χσ^(μν)iγ5χ)(qσ_(μν)q)with DM mass m_(χ)■10GeV,the latest PandaX constraint on the DM electric dipole moment puts more stringent bounds than the previous direct detection *** also briefly discuss the constraints obtained from experiments other than direct detection.

关键词： fermionic dark matter effective field theories tensor interactions

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Ore-proportioning optimization technique with high proportion of Yandi ore in sintering

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International Journal of Minerals,Metallurgy and Materials 2010年第1期17卷 11-16页

作者： Sheng-li Wu Hong-liang han Hai-xia Li Jian Xu Shi-dong Yang Xiao-qin Liu School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China Research Institute （R ＆ D Center） Baoshan Iron ＆ Steel Co. Ltd. Shanghai 201900 China Laiwu Iron and Steel Co. Ltd. Laiwu 271104 China

The basic sintering characteristics of Yandi ore from Australia, including assimilation ability, liquid phase fluidity, self-strength of bonding phase, forming ability of silico ferrite of calcium and aluminum （SFCA）, and so on, were investigated in detail. Besides, the high temperature behavior and function of sintering were obtained. As a result, the techniques for ore-proportioning in sintering were obtained. The results show that Yandi ore possessing higher assimilation ability, better liquid phase fluidity, lower self-strength of bonding phase, and better forming ability of SFCA, should be mixed with iron ores whose properties are opposite to those of Yandi ore. In the optimization of sintering ore-proportioning, Yandi ore, whose price is relatively low, can be mixed as high as 40wt%.

关键词： Yandi ore sintering high temperature behavior proportioning optimization

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Tracer Experimental Study of the Main Conveying Conduits of CCl_4 Pollutant in the Qiligou Water Supply Resource

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Journal of China University of Mining and Technology 2007年第2期17卷 184-187页

作者： PEI Zong-ping han Bao-ping LIU han-hu liang Zhi ZHOU Dong-lai ZHU Xue-qiang School of Environment and Spatial Informatics China University of Mining ＆ Technology Xuzhou Jiangsu 221008 China

The Ordovician karst groundwater in the Qiligou basin is an important water supply source. This groundwater has been seriously contaminated in recent years by Cfl4 from a pesticide plant located in the recharge area. The highest concentration of CCl4 in the groundwater is 3909.2μg/L. Large scale tracer experiments were carried out to study the conveying conduits for Cfl4 in the basin on May 1-6, 2005. Nontoxic, edible glucose was used as a tracer and it was detected by spectrophotometric techniques. Well area of the basin, was employed for injecting the tracer X-61, located near the pesticide plant in the southern recharge Ten wells widely located in the groundwater runoff area were used as observing and sampling wells. The results show that the migration of the pollutants is controlled by the water hydrodynamic field and by the development of karst conduits. The tracer did not enter the up-drainage wells, X-49 and X-47, near the injection point because the water levels at these wells are higher than at the injection point. The adjacent well X-62 is close to the injection site, but the tracer reached the well after eleven hours. Wells X-43, X-59, X-58, YY-1 and X-57, located in the syncline axis runoff area, are respectively 2.5, 3.5, 4.33, 4.38 and 5.44 kilometers from the in- jection site. The time for initial appearance of tracer was 4, 4, 2, 6 and 4 hours, respectively. The maximum runoff velocity （well X-58） is over two kilometers per hour, indicating that the karst conduits are well developed along the syncline basin axis. These conduits are the main conveying conduits for groundwater and Cfl4. Closer wells were not necessarily the first to receive tracer. This shows the inhomogeneity in karst development which causes complex runoff, and pollutant migration, patterns.

关键词： tracer experiment tracer karst groundwater CC14 contamination conveying conduit

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Positive impact of adding No.14v lymph node to D2 dissection on survival for distal gastric cancer patients after surgery with curative intent

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Chinese Journal of Cancer Research 2015年第6期27卷 580-587页

作者： Yuexiang liang liangliang Wu Xiaona Wang Xuewei Ding Hongmin Liu Bin Li Baogui Wang Yuan Pan Rupeng Zhang Ning Liu han liang Department of Gastric Cancer Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center of CancerKey Laboratory of Cancer Prevention and Therapy Department of Abdominal Cancer Hainan Province Cancer Hospital

Background： D2 lymphadenectomy has been increasingly regarded as standard surgical procedure for advanced gastric cancer （GC）, while the necessity of No.14v lymph node （14v） dissection for distal GC is still controversial. Methods： A total of 920 distal GC patients receiving at least a D2 lymph node dissection in Department of Gastric Cancer, Tianjin Medical University Cancer Institute and Hospital were enrolled in this study, of whom, 243 patients also had the 14v dissected. Other 677 patients without 14v dissection were used for comparison. Results： Forty-five （18.5%） patients had 14v metastasis. There was no significant difference in 3-year overall survival （OS） rate between patients with and without 14v dissection. Following stratified analysis, in TNM stages I, II, IIIa and IV, 14v dissection did not affect 3-year OS; in contrast, patients with 14v dissection had a significant higher 3-year OS than those without in TNM stages IIIb and IIIc. In multivariate analysis, 14v dissection was found to be an independent prognostic factor for GC patients with TNM stage IIIb/IIIc disease [hazard ratio （HR）, 1.568; 95% confidence interval （CI）： 1.186-2.072; P=0.002]. GC patients with 14v dissection had a significant lower locoregional, especially lymph node, recurrence rate than those without 14v dissection （11.7 % vs. 21.1%, P=0.035）. Conclusions： Adding 14v to D2 lymphadenectomy may be associated with improved 3-year OS for distal GC staged TNM IIIb/IIIc.

关键词： Gastric carcinoma No. 14v lymph node metastasis dissection prognosis

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Effects of extended lymphadenectomy and postoperative chemotherapy on node-negative gastric cancer

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World Journal of Gastroenterology 2013年第33期19卷 5551-5556页

作者： Qiang Xue Xiao-Na Wang Jing-Yu Deng Ru-Peng Zhang han liang Department of Gastric Cancer Surgery Tianjin Medical University Cancer Hospital and City Key Laboratory of Cancer Prevention and Therapy

AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node ***:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected,from January 2002 to December 2006,were analyzed *** with pT4 stage or distant metastasis were *** analyzed the relationship between the D2 lymphadenectomy and the 5-year survival rate among different subgroups stratified by clinical features,such as age,tumor size,tumor location and depth of *** the same time,the relationship between postoperative chemotherapy and the5-year survival rate among different subgroups were also ***:The overall 5-year survival rate of the entire cohort was 63.7%.The 5-year survival rate was poor in those patients who were:(1)more than 65 years old;(2)with tumor size larger than 4 cm;(3)with tumor located in the upper portion of the stomach;and(4)with pT3 *** survival rate was improved significantly by extended lymphadenectomy only in patients with pT3 tumor(P=0.019),but not in other ***,there was no significant difference in survival rate between patients with and without postoperative chemotherapy among all of the subgroups(P>0.05).CONCLUSION:For gastric cancer patients without lymph node metastasis,extended lymphadenectomy could improve the survival rate of those who have pT3-stage ***,there was no evidence of a survival benefit from postoperative chemotherapy alone.

关键词： Gastric cancer Lymph node negative metastasis Extended lymphadenectomy D2 lymphadenectomy Chemotherapy

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Constructing an ion‐oriented channel on a zinc electrode through surface engineering

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Carbon Energy 2023年第11期5卷 2-14页

作者： Xin Liu Kun Wang Ying Liu Fuhua Zhao Jianjiang He Hao Wu Jianfei Wu han‐Pu liang Changshui Huang Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdaoChina Beijing National Laboratory for Molecular Sciences Organic Solids LaboratoryInstitute of ChemistryChinese Academy of SciencesBeijingChina Sino‐Danish Center for Education and Research Sino‐Danish CollegeUniversity of Chinese Academy of SciencesBeijingChina Department of Chemical and Biochemical Engineering Technical University of DenmarkLyngbyDenmark

The inherent shortcomings of a zinc anode in aqueous zinc‐ion batteries(ZIBs)such as zinc dendrites and side reactions severely limit their practical ***,to address these issues,an ion‐oriented transport channel constructed by graphdiyne(GDY)nanowalls is designed and grown in situ on the surface of a zinc *** vertically stacked GDY nanowalls with a unique hierarchical porous structure and mechanical properties form a nanomesh‐like interface on the zinc electrode,acting as an ion‐oriented channel,which can efficiently confine the segmented growth of zinc metal in microscopic regions of hundreds of *** those microscopic regions,the uniform domain current density is effortlessly maintained compared with a large surface area,thereby inhibiting zinc dendrites ***,due to the presence of the ion‐oriented channel,the modified zinc anode demonstrates long‐term stable zinc plating/stripping performance for more than 600 h at 1 mAh cm^(−2)in an aqueous *** addition,full‐cells coupled with MnO2 show high specific capacity and power density,as well as excellent cycling stability with a capacity retention of 82%after 5000 cycles at 1 A g^(−1).This work provides a feasible and accessible surface engineering approach to modify the electrode interface for confined and dendrite‐free zinc deposition in aqueous ZIBs.

关键词： dendrite graphdiyne ion‐oriented channel nanomesh interface zinc‐ion batteries

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Sintering characteristics of fluxes and their structure optimization

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International Journal of Minerals,Metallurgy and Materials 2011年第3期18卷 270-276页

作者： Gen-sheng Feng Sheng-li Wu Hong-liang han Luo-wen Ma Wei-zhong Jiang Xiao-qin Liu School of Metallurgical and Ecological Engineering University of Science and Technology Beijing Beijing 100083 China Iron-making Plant of Baosteel Branch Baoshan Iron ＆ Steel Co. Ltd. Shanghai 200941 China

Sintering characteristics of common fluxes and sintering blending ores, such as mineralization capacity, liquid generation capacity, consolidation strength, were examined to master the behavior and effect of fluxes in sintering. Based on fundamental studies, sinter pot tests were carried out to obtain the principles of optimizing the sinter flux structure. The results showed that strong mineralization capacity, liquid phase generation capacity, and consolidation strength were obtained as sintering blending ores combined with the calcareous flux, while rela-tively poor sintering characteristics were obtained as sintering blending ores combined with the magnesian flux. High reactive quicklime should be used as much as possible in the sintering mixture. It reached better sintering results while quicklime was used instead of limestone and its appropriate proportion in the sintering mixture was around 4wt%. On the premise of ensuring the MgO content, the dolomite amount should be decreased, and the substitution of quicklime for dolomite caused better sintering results. The granularity of serpentine should be re-fined with a proper size smaller than 2 mm. The application of the divided addition method brought the best sintering performance with 30wt% of quicklime and 70wt% of fuel.

关键词： fluxes sintering sintering characteristics structural optimization

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Suppressing Wnt signaling of the blood-tumor barrier to intensify drug delivery and inhibit lipogenesis of brain metastases

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2716-2731页

作者： Yang Tong Pei An Puxian Tang Rui Mu Yuteng Zeng hang Sun Mei Zhao Ziyan Lv Pan Wang Wanjun han Chunshan Gui Xuechu Zhen liang han Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences Soochow UniversitySuzhou 215123China Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development Soochow UniversitySuzhou 215123China

Lipogenesis is often highly upregulated in breast cancer brain metastases to adapt to intracranial low lipid *** inhibitors hold therapeutic potential but their intra-tumoral distribution is often blocked by the blood-tumor barrier(BTB).BTB activates its Wnt signaling to maintain barrier properties,e.g.,Mfsd2a-mediated BTB low ***,we reported VCAM-1-targeting nano-wogonin(W@V-NPs)as an adjuvant of nano-orlistat(O@V-NPs)to intensify drug delivery and inhibit lipogenesis of brain metastases.W@V-NPs were proven to be able to inactivate BTB Wnt signaling,downregulate BTB Mfsd2a,accelerate BTB vesicular transport,and enhance tumor accumulation of O@*** the ability to specifically kill cancer cells in a lipid-deprived environment with IC_(50) at 48 ng/mL,W@V-NPs plus O@V-NPs inhibited the progression of brain metastases with prolonged survival of model *** combination did not induce brain edema,cognitive impairment,and systemic toxicity in healthy *** Wnt signaling could safely modulate the BTB to improve drug delivery and metabolic therapy against brain metastases.

关键词： Lipogenesis Brain metastases Blood-tumor barrier Wnt signaling Drug delivery Fatty acid synthase Nanoparticles Combination therapy

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Predictive values of multidetector-row computed tomography combined with serum tumor biomarkers in preoperative lymph node metastasis of gastric cancer

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Chinese Journal of Cancer Research 2019年第3期31卷 453-462页

作者： Huihui Bai Jingyu Deng Nannan Zhang Huifang Liu Wenting He Jinyuan Liu han liang Department of Gastric Cancer Tianjin Medical University Cancer Institute & Hospital National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and Therapy Tianjin’s Clinical Research Center for Cancer

Objective: Multidetector-row computed tomography(MDCT) and serum tumor biomarkers are commonly used to evaluate the preoperative lymph node metastasis and the clinical staging of gastric cancer(GC). This study intends to evaluate the clinical predictive value of MDCT and serum tumor biomarkers in lymph node metastasis of ***: The clinicopathologic data of 445 GC patients who underwent radical gastrectomy were retrospectively analyzed to evaluate the diagnostic value of MDCT and serum tumor biomarkers in lymph node metastatic staging of GC before ***: With the multinomial logistic regression analysis, the independent relative factors of lymph node metastasis of GC were identified as tumor size, depth of tumor invasion, vessel invasion, vascular embolus, and soft tissue invasion. The optimal critical value of the short diameter of lymph nodes detected by MDCT scanning for evaluation of preoperative lymph node metastasis was 6.0 mm, with 75.7% as predictive accuracy of lymph node metastasis compared to the postoperative pathological results of GC patients. In addition, the critical value of the short diameter of lymph nodes combined with serum tumor biomarkers [including carbohydrate antigen(CA)-724 and CA-199] could show an enhancement of predictive sensitivity of lymph node metastasis(up to 89.3%) before ***: MDCT combined with serum tumor biomarkers should be adopted to improve preoperative sensitivity and accuracy of lymph node metastasis for GC patients.

关键词： Gastric cancer MDCT serum tumor biomarkers preoperative

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10MW高温气冷堆蒸汽发生器传热小螺旋管流致振动分析

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核动力工程 2001年第3期22卷 232-235,247页

作者： BO han-liang 薄涵亮马昌文 Institute of Nuclear Energy Technology Tsinghua University北京100084 清华大学核能技术设计研究院

根据10MW高温气冷堆(HTR-10)蒸汽发生器传热小螺旋管的具体结构，提出了相应的计算模型；针对传热管振动的主要机理、流体弹性不稳定、旋涡脱落和湍流激励，依据目前所能够查阅到的文献资料中提供的半经验模型，做了详细分析和校核计算... 详细信息

根据10MW高温气冷堆(HTR-10)蒸汽发生器传热小螺旋管的具体结构，提出了相应的计算模型；针对传热管振动的主要机理、流体弹性不稳定、旋涡脱落和湍流激励，依据目前所能够查阅到的文献资料中提供的半经验模型，做了详细分析和校核计算。分析结果表明， HTR- 10蒸汽发生器在设计工况下运行时，不会发生流体弹性不稳定所导致的大振幅振动，也不会产生旋涡脱落引起的联锁共振；湍流激励对小螺旋管振动的影响很小。它在避免流致振动方面的设计是安全、可靠的。

关键词：高温气冷堆流致振动蒸汽发生器传热小螺旋管固有频率

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