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Hydration lubrication modulated by water structure at TiO2–aqueous interfaces

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Friction 2024年第4期12卷 591-605页

作者： Pingsu MA Yuan LIU ke han Yu TIAN Liran MA State key Laboratory of Tribology in Advanced Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China

The nature of solid-liquid interfaces is of great significance in *** advances have been made in lubrication based on hydration ***,a detailed molecular-level understanding is still ***,we investigated water molecule behaviors at the TiO2-aqueous interfaces by the sum-frequency generation vibrational spectroscopy(SFG-VS)and atomic force microscope(AFM)to elucidate the fundamental role of solid-liquid interfaces in *** contributions of water structures and hydration effects were revealed,where water structures played the dominant role in lubrication for TiO2 surfaces of varying hydrophilicity,while hydration effects dominated with the increasing of ion *** lubrication is observed on the initial TiO2 surfaces with strongly H-bonded water molecules compared to the hydrophilic TiO2 surfaces with more disordered *** stable ordered water arrangement with strong hydrogen bonds and the shear plane occurring between the ordered water layer and subsequent water layer may play a significant role in achieving lower *** adsorbed hydrated molecules with the increasing ionic concentration perturb ordered water but lead to the enhancement of hydration effects,which is the main reason for the improved lubrication for both *** work provides more insights into the detailed molecular-level understanding of the mechanism of hydration lubrication.

关键词： hydration lubrication interfacial water structures hydration effects titanium dioxide(TiO2)

A Dietary Supplement Jinghuosu Ameliorates Reproductive Damage Induced by Tripterygium Glycosides

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Chinese Journal of Integrative Medicine 2024年第4期30卷 330-338页

作者： MA Jing SUN Bo TE Li-ger HUANG Xin ZUO Xin han Xiao-ke WANG Shu-song Hebei key Laboratory of Reproductive Medicine Hebei Institute of Reproductive HealthHebei Reproductive Health HospitalShijiazhuang(050071)China Graduate School of Hebei Medical University Shijiazhuang(050017)China School of Chemistry and Materials Science Hebei Normal UniversityShijiazhuang(050024)China Xingtai Infertility Specialist Hospital XingtaiHebei Province(054000)China

Objective To determine the possible protective effects of Jinghuosu,a dietary supplement(DS),on tripterygium glycosides(TG)-induced reproductive system injury in rats and its underlying *** A reproductive damage model was established in rats by feeding of ***-eight male Sprague Dawley rats were randomly divided into 4 groups using a random number table(n=7 in each):control(C)group,model(M)group,DS group and L-carnitine(LC)*** in M,DS and LC groups received 40 mg/kg TGs *** from the 5th week,after administration of TGs for 4 h every day,rats in DS and LC groups were administered with 2.7 g/kg DS and 0.21 g/kg LC,respectively,for protective treatment over the next 4 *** in Group C continued to receive the control ***-eosin staining was used for histopathological analysis of rat testicular ***-linked immunosorbent assay was performed to measure alkaline phosphatase(ALP),lactate dehydrogenase,alcohol dehydrogenase,total antioxidant capacity(T-AOC),superoxide dismutase,glutathione peroxidase(GSH-Px),and malondialdehyde(MDA)*** assay was used to determine the serum testosterone *** real-time PCR and Western blotting were conducted to analyze the expression of genes and proteins related to the testosterone synthesis pathway and the nuclear factor erythroid 2-related factor 2/heme oxygenase 1 antioxidant *** Oral administration of TGs induced significant increases in the testicular levels of zinc transporter 1 and MDA(Phand,sperm concentration,sperm motility,and serum testosterone,serum zinc,testicular zinc,Zrt-,Irt-like protein 1,ALP,luteinizing hormone(LH)receptor,steroidogenic acute regulatory protein,Cytochrome P450 family 11 subfamily A member 1,3β-hydroxysteroid dehydrogenase 1 T-AOC,GSH-Px,nuclear factor erythroid 2-related factor 2,heme oxygenase-1 and NAD(P)H:quinone oxidoreductase 1 levels decreased following TG

关键词： dietary supplement Jinghuosu tripterygium glycosides reproductive damage infertility

Role of submucosal injection in radiofrequency ablation of gastric low-grade dysplasia: Effects on symptoms and outcomes

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中华医学杂志(英文版) 2024年第17期137卷 2099-2110页

作者： Niu Xiaotong Wang Nanjun Wang Yan Feng Jia Li Longsong han ke Chai Ningli Linghu Enqiang Medical School of Chinese PLA General Hospital Beijing China Department of Gastroenterology and Hepatology The First Medical Center Chinese PLA General Hospital Beijing China Nankai University School of Medicine Nankai University Tianjin China Department of Gastroenterology Bethune International Peace Hospital ShijiaZhuang Hebei China

Background: To date, there is still a lack of standardized management strategies for gastric low-grade dysplasia (LGD), which is a direct neoplastic precancerous lesion and requires specifically superficial destruction. Radiofrequency ablation (RFA) is expected to be an effective method for gastric LGD, but post-RFA pain may affect patients’ satisfaction and compliance. The current study aimed to evaluate the value of a submucosal injection prior to RFA (SI-RFA) for postoperative pain and treatment ***: Between October 2014 and July 2021, gastric LGDs without risk factors (size >2 cm, unclear boundary, and abnormal microsurface and microvascularity) undergoing regular RFA and SI-RFA were retrospectively analyzed. Postoperative pain scores, wound healing, and clinical efficacy were compared. Propensity score matching, stratified analysis, and multivariable logistic regression were performed to control the confounding ***: One hundred and ninety-seven gastric LGDs in 151 patients received regular RFA. Forty-nine gastric LGDs in 36 patients received SI-RFA. Thirty-six pairs of patients were selected for the assessment of postoperative pain by propensity score matching. Compared to regular RFA, SI-RFA significantly decreased the degree and duration of postoperative pain (OR, 0.32; 95% CI, 0.13-0.84;P = 0.020), improved wound healing rate (80.0% [36/45]vs. 58.9% [89/151],P = 0.012), increased the complete ablation rate (91.8% [45/49]vs. 86.3% [170/197],χ2 = 1.094,P = 0.295), but correlated with higher rates of local recurrence and progression (25.6% [10/39]vs. 13.2% [18/136],χ2 = 3.471,P = 0.062; 8.3% [3/36]vs. 0.9% [1/116],P = 0.042). The multivariable logistic regression model confirmed that submucosal injection was associated with local recurrence (OR, 2.93; 95% CI, 1.13-7.58;P = 0.027).Conclusions: Submucosal injections prior to RFA may reduce postoperative pain and scar formation while ensuring complete ablation of gastric LGD. However, lo

关键词： Gastric low-grade dysplasia Radiofrequency ablation Submucosal injection Postoperative pain Treatment outcome

Transcriptome analysis suggests broad jejunal alterations in Linghu’s obesity-diarrhea syndrome:A pilot study

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World Journal of Gastroenterology 2024年第21期30卷 2777-2792页

作者： Xiao-Tong Niu Xiang-Yao Wang Yan Wang ke han Nan Ru Jing-Yuan Xiang En-Qiang Linghu Medical School of Chinese PLA Chinese PLA General HospitalBeijing 100853China Department of Gastroenterology The First Medical Center of Chinese PLA General HospitalBeijing 100853China School of Medicine Nankai UniversityTianjin 300071China

BACKGROUND Obesity is associated with a significantly increased risk for chronic diarrhea,which has been proposed as Linghu’s obesity-diarrhea syndrome(ODS);however,its molecular mechanisms are largely *** To reveal the transcriptomic changes in the jejunum involved in *** In a cohort of 6 ODS patients(JOD group),6 obese people without diarrhea(JO group),and 6 healthy controls(JC group),high-throughput sequencing and bioinformatics analyses were performed to identify jejunal mucosal mRNA expression alterations and dysfunctional biological *** another cohort of 16 ODS patients(SOD group),16 obese people without diarrhea(SO group),and 16 healthy controls(SC group),serum diamine oxidase(DAO)and D-lactate(DLA)concentrations were detected to assess changes in intestinal barrier *** The gene expression profiles of jejunal mucosa in the JO and JC groups were similar,with only 1 differentially expressed gene(DEG).The gene expression profile of the JOD group was significantly changed,with 411 DEGs compared with the JO group and 211 DEGs compared with the JC group,129 of which *** enrichment analysis of these DEGs showed that the biological processes such as digestion,absorption,and transport of nutrients(especially lipids)tended to be up-regulated in the JOD group,while the biological processes such as rRNA processing,mitochondrial translation,antimicrobial humoral response,DNA replication,and DNA repair tended to be down-regulated in the JOD *** DEGs(CDT1,NHP2,EXOSC5,EPN3,NME1,REG3A,PLA2G2A,and PRSS2)may play a key regulatory role in the pathological process of ODS,and their expression levels were significantly decreased in ODS patients(Pkers(DAO and D-LA)were significantly increased in all obese individuals(Phan in the SO group(P<0.001).CONCLUSION Compared with health

关键词： Obesity Chronic diarrhea Jejunum Transcriptome Intestinal barrier

Dynamical localization in a non-Hermitian Floquet synthetic system

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Chinese Physics B 2024年第5期33卷 147-151页

作者：可汗张嘉明霍良赵文垒 School of Science Jiangxi University of Science and TechnologyGanzhou 341000China School of Information Engineering Jiangxi University of Science and TechnologyGanzhou 341000China

We investigate the non-Hermitian effects on quantum diffusion in a kicked rotor model where the complex kicking potential is quasi-periodically modulated in the time *** synthetic space with arbitrary dimension can be created by incorporating incommensurate frequencies in the quasi-periodical *** the Hermitian case,strong kicking induces the chaotic diffusion in the four-dimension momentum space characterized by linear growth of mean *** find that the quantum coherence in deep non-Hermitian regime can effectively suppress the chaotic diffusion and hence result in the emergence of dynamical ***,the extent of dynamical localization is dramatically enhanced by increasing the non-Hermitian ***,the quasi-energies become complex when the non-Hermitian parameter exceeds a certain threshold *** quantum state will finally evolve to a quasi-eigenstate for which the imaginary part of its quasi-energy is large *** exponential localization length decreases with the increase of the non-Hermitian parameter,unveiling the underlying mechanism of the enhancement of the dynamical localization by nonHermiticity.

关键词： Floquet system non-Hermitian physics dynamical localization

Design of a novel hybrid quantum deep neural network in INEQR images classification

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Chinese Physics B 2024年第6期33卷 230-238页

作者：王爽王柯涵程涛赵润盛马鸿洋郭帅 School of Information and Control Engineering Qingdao University of TechnologyQingdao 266033China School of Sciences Qingdao University of TechnologyQingdao 266033China

We redesign the parameterized quantum circuit in the quantum deep neural network, construct a three-layer structure as the hidden layer, and then use classical optimization algorithms to train the parameterized quantum circuit, thereby propose a novel hybrid quantum deep neural network(HQDNN) used for image classification. After bilinear interpolation reduces the original image to a suitable size, an improved novel enhanced quantum representation(INEQR) is used to encode it into quantum states as the input of the HQDNN. Multi-layer parameterized quantum circuits are used as the main structure to implement feature extraction and classification. The output results of parameterized quantum circuits are converted into classical data through quantum measurements and then optimized on a classical computer. To verify the performance of the HQDNN, we conduct binary classification and three classification experiments on the MNIST(Modified National Institute of Standards and Technology) data set. In the first binary classification, the accuracy of 0 and 4 exceeds98%. Then we compare the performance of three classification with other algorithms, the results on two datasets show that the classification accuracy is higher than that of quantum deep neural network and general quantum convolutional neural network.

关键词： quantum computing image classification quantum–classical hybrid neural network quantum image representation interpolation

数字鸿沟与中国式现代化:理论分析与实证检验

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管理现代化 2024年第2期44卷 190-200页

作者：赵若男克甝新疆财经大学统计与数据科学学院新疆乌鲁木齐830012

选取2014-2022年30个省市区的面板数据,从理论分析与实证检验的角度探讨了数字鸿沟对中国式现代化的影响。结论:数字鸿沟是阻碍中国式现代化发展的显著因素;数字鸿沟对中国式现代化发展的影响主要集中于使用鸿沟,但有向结果鸿沟转移的趋... 详细信息

选取2014-2022年30个省市区的面板数据,从理论分析与实证检验的角度探讨了数字鸿沟对中国式现代化的影响。结论:数字鸿沟是阻碍中国式现代化发展的显著因素;数字鸿沟对中国式现代化发展的影响主要集中于使用鸿沟,但有向结果鸿沟转移的趋势;数字鸿沟对中国式现代化发展的影响呈边际递增趋势;数字鸿沟对中国式现代化发展的影响具有北部地区大于南部地区、西部地区大于东中部地区的特征;数字鸿沟通过降低市场主体活力、扩大城乡居民收入差距和减缓产业结构升级速度,阻滞中国式现代化发展。

关键词：使用鸿沟中国式现代化梅特卡夫定律边际递增

Decoding topological XYZ^(2) codes with reinforcement learning based on attention mechanisms

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Chinese Physics B 2024年第6期33卷 262-270页

作者：陈庆辉姬宇欣王柯涵马鸿洋纪乃华 School of Information and Control Engineering Qingdao University of TechnologyQingdao 266033China School of Sciences Qingdao University of TechnologyQingdao 266033China

Quantum error correction, a technique that relies on the principle of redundancy to encode logical information into additional qubits to better protect the system from noise, is necessary to design a viable quantum computer. For this new topological stabilizer code-XYZ^(2) code defined on the cellular lattice, it is implemented on a hexagonal lattice of qubits and it encodes the logical qubits with the help of stabilizer measurements of weight six and weight two. However topological stabilizer codes in cellular lattice quantum systems suffer from the detrimental effects of noise due to interaction with the environment. Several decoding approaches have been proposed to address this problem. Here, we propose the use of a state-attention based reinforcement learning decoder to decode XYZ^(2) codes, which enables the decoder to more accurately focus on the information related to the current decoding position, and the error correction accuracy of our reinforcement learning decoder model under the optimisation conditions can reach 83.27% under the depolarizing noise model, and we have measured thresholds of 0.18856 and 0.19043 for XYZ^(2) codes at code spacing of 3–7 and 7–11, respectively. our study provides directions and ideas for applications of decoding schemes combining reinforcement learning attention mechanisms to other topological quantum error-correcting codes.

关键词： quantum error correction topological quantum stabilizer code reinforcement learning attention mechanism

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一种冗余机械臂逆运动学求解和优化方法

华中科技大学学报（自然科学版） 2024年第5期52卷 123-129页

作者：李世其贺平韩可张智勇华中科技大学机械科学与工程学院湖北武汉430074

为解决冗余机械臂逆运动学求解困难的问题,提出一种基于关节角参数的逆运动学求解和优化方法.首先推导了正向运动学,并基于关节角参数化法得出了解析逆运动学;然后提出综合考虑避关节极限约束与运动连续性约束的目标函数,该目标函数充... 详细信息

为解决冗余机械臂逆运动学求解困难的问题,提出一种基于关节角参数的逆运动学求解和优化方法.首先推导了正向运动学,并基于关节角参数化法得出了解析逆运动学;然后提出综合考虑避关节极限约束与运动连续性约束的目标函数,该目标函数充分考虑了不同工作状态的差异性;最后引入带惯性权重的粒子群算法加快求解速度.实验结果表明:逆运动学求解平均时长为1.19μs,误差在10 nm以内,能够求出给定参数值的所有解,结合避关节极限和运动连续性的优化目标能够求出最优解,在直线与圆弧两种路径跟踪实验中比传统方法分别提高了68.4%和58.0%的优化效果.

关键词：冗余机械臂逆运动学优化解析解关节角参数化粒子群算法