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Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Female Breast Cancer—China,2003-2017

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China CDC weekly 2023年第15期5卷 340-346,I0001页

作者： Kexin Sun Lin Lei Rongshou Zheng Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen bingfeng han Ji Peng Wenqiang Wei Jie He National Central Cancer Registry National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Shenzhen Center for Chronic Disease Control Shenzhen CityGuangdong ProvinceChina Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Introduction:This study reported the trends in female breast cancer incidence and mortality rates in China,and analyzed the corresponding age-periodcohort ***:Data from 22 population-based cancer registries in China between 2003 and 2017 were ***-standardized incidence rates(ASIR)and mortality rates(ASMR)were calculated using Segi’s world standard *** regression was employed to evaluate trends,and age-period-cohort effects were examined using the intrinsic estimator ***:The ASIR for female breast cancer exhibited a more rapid increase in rural areas compared to urban areas across all age *** most substantial increase was observed in the 20-34 age group in rural areas[annual percent change(APC)=9.0%,95%confidence interval(CI):7.0%-11.0%,P<0.001].The ASMR for females under 50 years old remained stable from 2003 to 2017 in both urban and rural ***,the ASMR for females over 50 in rural areas and those over 65 in urban areas demonstrated a significant increase,with the most pronounced increase observed among females over 65 in rural areas(APC=4.9%,95%CI:2.8%-7.0%,P<0.001).Age-period-cohort analysis revealed increasing period effects and decreasing cohort effects for female breast cancer incidence and mortality rates in both urban and rural ***,the cohort effect for incidence displayed a slight upward trend for females born between 1983 and 1992 in rural ***:Our study revealed a rapid increase in breast cancer incidence among younger generations and an accelerated mortality rate in older populations residing in rural *** effectively address the growing burden of female breast cancer in China,it is essential to develop and implement targeted intervention strategies.

关键词： mortality Breast younger

Cancer incidence and mortality in China,2022

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Journal of the National Cancer Center 2024年第1期4卷 47-53页

作者： bingfeng han Rongshou Zheng Hongmei Zeng Shaoming Wang Kexin Sun Ru Chen Li Li Wenqiang Wei Jie He Office for Cancer Registry National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

Background:The National Cancer Center(NCC)of China regularly reports the nationwide statistics on cancer incidence and mortality in *** International Agency for Research on Cancer(IARC)calculates and publishes the cancer burden of countries around the world every two *** ensure consistency between the actual surveillance data in China and the data published by IARC,NCC has received approval from the National Health Commission and IARC to simultaneously release the cancer burden data for China in GLOBOCAN ***:There were a total of 700 registries reporting high-quality data on cancer incidence and mortality across China in 2018,of which 106 registries with continuous monitoring from 2010 to 2018 were used to establish an age-period-cohort model to simulate the trend of cancer incidence and mortality and to estimate the incidence and mortality in China in *** addition,we analyzed the temporal trends of age-standardized cancer incidence and mortality from 2000 to 2018 using data from 22 continuous cancer ***:It was estimated about 4,824,700 new cancer cases and 2,574,200 new cancer deaths occurred in China in *** of the lung,colon-rectum,thyroid,liver and stomach were the top five cancer types,accounting for 57.42%of new cancer *** of the lung,liver,stomach,colon-rectum and esophagus were the five leading causes of cancer deaths,accounting for 67.50%of total cancer *** crude rate and age-standardized incidence rate(ASIR)were 341.75 per 100,000 and 201.61 per 100,000,*** crude mortality rate was 182.34 per 100,000 and the age-standardized mortality rate(ASMR)was 96.47 per 100,*** ASIR of all cancers combined increased by approximately 1.4%per year during 2000–2018,while the ASMR decreased by approximately 1.3%per *** observed decreasing trends in ASIR and ASMR for cancers of the esophagus,stomach,and liver,whereas the ASIR increased significantly for cancers of the thyroid,prostate,and

关键词： Cancer registry Incidence Mortality Statistics China

Trends in Incidence Rates,Mortality Rates,and Age-Period-Cohort Effects of Cervical Cancer—China,2003–2017

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China CDC weekly 2022年第48期4卷 1070-1076,I0001-I0010页

作者： Kexin Sun Rongshou Zheng Lin Lei Siwei Zhang Hongmei Zeng Shaoming Wang Li Li Ru Chen bingfeng han Ji Peng Wenqiang Wei Jie He National Central Cancer Registry National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing MunicipalityChina Shenzhen Center for Chronic Disease Control Guangzhou CityGuangdong ProvinceChina Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing MunicipalityChina.

Introduction:This study reported the trends and analyzed the age-period-cohort effects on the incidence and mortality rates of cervical cancer in ***:The age-standardized incidence rate(ASIR)and mortality rate(ASMR)by Segi’s world standard population were calculated using qualified consecutive data from 22 cancer registries from 2003 to 2017 in *** performed joinpoint analysis to describe the trends and age-period-cohort analysis to estimate the independent effects of age,period and cohort on trends in incidence and mortality rates of cervical ***:The ASIR and ASMR for cervical cancer in females over 20 years old increased during 2003−*** females50 years,the ASIR and ASMR increased both in urban and rural ***-period-cohort analysis showed increasing period effects on cervical cancer incidence and mortality during the whole *** cohort effects exhibited a downward-upwarddownward pattern for the incidence(1918–1938,1938–1963,1963–1993)and mortality rates(1918–1943,1943–1963,1963–1993)in urban areas,a fluctuating pattern for incidence rate and a continuing downward pattern for mortality rate(1918–1993)in rural ***:The increases in cervical cancer incidence and mortality rates can be mostly explained by period *** observed decreases in risk for cervical cancer incidence and mortality in young female generations,which were more obvious in urban areas.

关键词： mortality Cervical downward

Cancer survival statistics in China 2019-2021:a multicenter,population-based study

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Journal of the National Cancer Center

Journal of the National Cancer Center 2024年第3期4卷 203-213页

作者： Hongmei Zeng Rongshou Zheng Kexin Sun Maigeng Zhou Shaoming Wang Li Li Ru Chen bingfeng han Meicen Liu Jinhui Zhou Mengyuan Xu Lijun Wang Peng Yin Baohua Wang Jinling You Jing Wu Wenqiang Wei Jie He National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina National Center for Chronic and Non-communicable Disease Control and Prevention Chinese Center for Disease Control and PreventionBeijingChina

Background:A milestone goal of the Healthy China Program(2019-2030)is to achieve 5-year cancer survival at 43.3%for all cancers combined by *** assess the progress towards this target,we analyzed the updated survival for all cancers combined and 25 specific cancer types in China from 2019 to ***:We conducted standardized data collection and quality control for cancer registries across 32 provincial-level regions in China,and included 6,410,940 newly diagnosed cancer patients from 281 cancer registries during 2008-2019,with follow-up data on vital status available until December *** estimated the age-standardized 5-year relative survival overall and by site,age group,and period of diagnosis using the International Cancer Survival Standard Weights,and quantified the survival changes to assess the progress in cancer ***:In 2019-2021,the age-standardized 5-year relative survival for all cancers combined was 43.7%(95%confidence interval[CI],43.6-43.7).The 5-year relative survival varied by cancer type,ranging from 8.5%(95%CI,8.2-8.7)for pancreatic cancer to 92.9%(95%CI,92.4-93.3)for thyroid *** cancers had 5-year survival of over 60%,including cancers of the thyroid,breast,testis,bladder,prostate,kidney,uterus,and *** 5-year relative survival was generally lower in males than in *** 2008 to 2021,we observed significant survival improvements for cancers of the lung,prostate,bone,uterus,breast,cervix,nasopharynx,larynx,and *** most significant improvement was in lung ***:Progress in cancer control was evident in *** highlights the importance of a comprehensive approach to control and prevent cancer.

关键词： Cancer survival Healthy China 2030 Population-based Policy evaluation China

国产肠道病毒71型灭活疫苗临床免疫原性研究进展

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中国疫苗和免疫 2017年第4期23卷 471-476页

作者：韩冰峰崔富强北京大学公共卫生学院流行病与卫生统计学系北京100191

手足口病(hand,foot and mouth disease,HFMD)是一种急性传染病,高发人群是婴幼儿。2015年12月国家食品药品监督管理总局批准两家国产肠道病毒71型(EV71)灭活疫苗上市,该疫苗很可能使中国大陆成为第一个用疫苗预防儿童HFMD的地区。本研... 详细信息

手足口病(hand,foot and mouth disease,HFMD)是一种急性传染病,高发人群是婴幼儿。2015年12月国家食品药品监督管理总局批准两家国产肠道病毒71型(EV71)灭活疫苗上市,该疫苗很可能使中国大陆成为第一个用疫苗预防儿童HFMD的地区。本研究分析评价了临床研究中6-35月龄儿童接种EV71疫苗后的免疫原性,以及疫苗上市后需要关注的问题。

关键词：预肠道病毒71型灭活疫苗临床免疫原性几何平均滴度抗体阳转率

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阻尼板式波浪压电换能装置研究

太阳能学报 2014年第8期35卷 1387-1393页

作者：姚斐褚金奎韩冰峰霍新新熊叶胜大连理工大学精密与特种加工教育部重点实验室大连116023 辽宁省微纳米技术及系统重点实验室大连116023

设计一种阻尼板点吸收式波浪压电发电装置;建立系统的动力学模型,采用基于格林函数的高阶边界元法对装置浮体的水动力学系数和波浪力进行计算;通过数值仿真方法分析波高、波浪周期、阻尼板尺寸和弹簧刚度对装置性能的影响。研究结果表明... 详细信息

设计一种阻尼板点吸收式波浪压电发电装置;建立系统的动力学模型,采用基于格林函数的高阶边界元法对装置浮体的水动力学系数和波浪力进行计算;通过数值仿真方法分析波高、波浪周期、阻尼板尺寸和弹簧刚度对装置性能的影响。研究结果表明,浮漂体与阻尼板之间的相对位移幅值随着波高的增加几乎是线性增加的;相对位移幅值随波浪周期变化的规律与波浪力大小随波周期变化的规律一致,当周期达到4.5 s时相对位移幅值最大,然后趋于稳定;在弹簧刚度k=150 N/m的情况下,当阻尼板尺寸为L=0.35 m时相对位移幅值最大。可为进一步设计样机提供理论参考。

关键词：波浪能阻尼板压电边界元法

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整流二极管对压电输出模型的影响性研究

压电与声光 2014年第3期36卷 468-469,473页

作者：霍新新褚金奎韩冰峰大连理工大学精密与特种加工教育部重点实验室辽宁大连116023 辽宁省微纳米技术及系统重点实验室辽宁大连116023

为了提高压电换能器理论模型的精度,基于标准电路,在考虑整流二极管压降的基础上,建立了更准确的压电换能器理论模型,得出系统输出功率的表达式,并给出了等效质量的位移推导过程。对比传统模型,通过仿真分析揭示了整流二极管对压电输出... 详细信息

为了提高压电换能器理论模型的精度,基于标准电路,在考虑整流二极管压降的基础上,建立了更准确的压电换能器理论模型,得出系统输出功率的表达式,并给出了等效质量的位移推导过程。对比传统模型,通过仿真分析揭示了整流二极管对压电输出的影响规律。结果表明,在考虑整流二极管压降的基础上,接口电路实际最优匹配负载有少量增加趋势;随着整流二极管压降的增加,输出功率峰值呈递减趋势;输出频带宽也相应减小。

关键词：压电换能器标准电路整流二极管功率峰值功耗

Incidence, mortality, and disability-adjusted life years of female breast cancer in China, 2022

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中华医学杂志(英文版) 2024年第20期137卷 2429-2436页

作者： Sun Kexin Zhang Bailin Lei Shaoyuan Zheng Rongshou Liang Xin Li Li Feng Xiaolong Zhang Siwei Zeng Hongmei Yao Yifei Ma Peiqing Wang Shaoming Chen Ru han bingfeng Wei Wenqiang He Jie Office of Cancer Registry National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Breast Surgical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Evidence-Based Medicine Xuanwu Hospital Capital Medical University Beijing China Medical Statistics Office National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Pathology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Thoracic Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China

Background: Breast cancer is ranked among the most prevalent malignancies in the Chinese female population. However, comprehensive reports detailing the latest epidemiological data and attributable disease burden have not been extensively ***: In 2018, high-quality cancer surveillance data were recorded in 700 population-based cancer registries in China. We extracted data on female breast cancers (International Classification of Diseases, Tenth Revision [ICD-10]: C50) and estimated the incidence and mortality in 2022 according to the baseline data and corresponding trends from 2010 to 2018. Pathological types were classified according to the ICD for Oncology, 3rd Edition codes. Disability-adjusted life years (DALYs) were calculated as the sum of the years of life lost (YLLs) and years lived with disability (YLDs).Results: In 2022, approximately 357,200 new female breast cancer cases and 75,000 deaths occurred in China, accounting for 15.59% and 7.94% of total new cancer cases and deaths, respectively. The age-standardized incidence rate (ASIR) was 33.04 per 100,000. When analyzed by pathological type, the ASIRs for papillary neoplasms, invasive breast carcinoma, rare and salivary gland-type tumors, and other types were 1.13, 29.79, 0.24, and 1.88 per 100,000, respectively. The age-standardized mortality rate (ASMR) was 6.10 per 100,000. A total of 2,628,000 DALYs were found to be attributable to female breast cancer in China, comprising 2,278,300 YLLs and 349,700 YLDs. The ASIR, ASMR, and age-standardized rate (ASR) for DALYs in urban areas were consistently higher than those in rural areas. We observed a four-fold increase in the ASIR and ASR for DALYs and an eight-fold increase in the ASMR among females over 55 years compared with those aged under 55 ***: These data provide invaluable insights into the latest epidemiology of female breast cancer in China and highlight the urgency for disease prevention and control strategy formulation.

关键词： Female Breast cancer Incidence Mortality DALYs China Early detection of cancer Disease burden Invasive breast carcinoma Quality of life

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浅谈泥水平衡法顶管在龙门供水工程中的应用

山西科技 2015年第3期30卷 157-159页

作者：韩秉凤太原理工大学山西太原030000 吕梁市柏叶口水库供水建设管理局山西交城030500

以龙门供水工程为例,介绍了泥水平衡法施工段工程概况,阐述了泥水平衡法施工方案,分析了泥水平衡法顶管较普通套管法顶管的优缺点。

关键词：龙门供水工程泥水平衡法顶管