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Ankylosing spondylitis: A state of the art factual backbone

World Journal of Radiology 2015年第9期7卷 236-252页

作者： Mohammad Ghasemi-rad Hosam Attaya Emal Lesha Andrea Vegh Tooraj Maleki-Miandoab Emad Nosair Nariman Sepehrvand Ali Davarian hamid rajebi Abdolghader Pakniat Seyed Amirhossein Fazeli Afshin Mohammadi Division of Inter-ventional Radiology Massachusetts General Hospital Harvard Medical School Harvard--MIT Division of Health Sciences and Technology Mass-achusetts Institute of Technology College of Science and Mathematics University of Massachusetts Boston Department of Materials Science and Engineering Faculty of Applied Science and Engineering University of Toronto Department of Radiology Urmia University of Medical Sciences Anatomical Sciences Basic Medical Sciences Department College of Medicine Sharjah University Department of Medicine University of Alberta Ischemic Disorders Research Center Golestan University of Medical Sciences Radiology Department SUNY Upstate Medical University Department of Emergency Medicine Arak University of Medical Science Department of Medicine Zahedan University of Medical Sciences Solid Tumor Research Center Imam Khomaini Hospital University of Medical Sciences

Ankylosing spondylitis(AS) is a chronic inflammatory disease that affects 1% of the general population. As one of the most severe types of spondyloarthropathy, AS affects the spinal vertebrae and sacroiliac joints, causing debilitating pain and loss of mobility. The goal of this review is to provide an overview of AS, from the pathophysiological changes that occur as the disease progresses, to genetic factors that are involved with its onset. Considering the high prevalence in the population, and the debilitating life changes that occur as a result of the disease, a strong emphasis is placed on the diagnostic imaging methods that are used to detect this condition, as well as several treatment methods that could improve the health of individuals diagnosed with AS.

关键词： Ankylosing spondylitis Magnetic resonance imaging

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