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Characteristics of turbulent flow in 3-D pools in the presence of submerged rigid vegetation in channel bed

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Journal of Hydrodynamics 2024年第1期36卷 158-169页

作者： Kourosh Nosrati Hossein Afzalimehr Jueyi Sui hamid reza Reisifar Natural Disasters Prevention Research Center Faculty of Civil EngineeringIran University of Science and TechnologyTehranIran School of Engineering University of Northern British ColumbiaPrince GeorgeCanada

In this study,the interaction between 3-D bedforms and submerged rigid vegetation has been *** laboratory experiments were conducted to study the distribution of flow velocity,Reynolds shear stress,turbulent kinetic energy,and skewness coefficients for a constant density of *** showed that the velocity profile in the pool section deviates from those in the upstream section of the *** has been found that the dip parameter varied between 0.6H and 0.9H depending on various factors including bed roughness,vegetation distribution,and pool entrance/exit ***,scattered vegetation in the pool and differences in slopes created non-uniform flow ***,in the wake region behind each vegetated element,flow velocity reduced significantly,and small-scale eddies are formed,causing increased *** decreasing the entrance slope and bed roughness,relatively uniform flow and weaker turbulence was resulted,but the random distribution of vegetated elements counteracted this balance and intensified *** the decrease in the pool entrance slope,the contribution of sweep event decreased and the contribution of ejection event increased.

关键词： Submerged rigid vegetation 3-D pool Reynolds shear stress skewness coefficients

Effects of heat stress and long photoperiod on the prostate of rats

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Asian pacific Journal of Reproduction 2024年第4期13卷 187-196页

作者： hamid reza Ghaffari Javad Poursamimi Department of Basic Sciences School of MedicineZabol University of Medical SciencesZabolIran Department of Immunology Faculty of MedicineZabol University of Medical SciencesZabolIran

Objective:To examine light and heat effects on the morphological,histological,and micrometric structure of the prostate of ***:Thirty adult male rats were divided into three *** control group was kept under 20℃-22℃ and an artificial 12 h/12 h day/night cycle;the temperature group was under normal light and at(42±1)℃ heat for 4 to 5 h daily,and the light group was exposed to 8 h/16 h day/night cycle with 20℃-22℃.Rats were weighed five times(at the beginning of the study and every seven days).Five milliliters(mL)of their peripheral blood were *** tissue staining was performed using the hematoxylin-eosin(H&E)stain and periodic acid-Schiff(PAS).In the following,tissue and cellular reactions to the PAS were ***:Folds were located entirely on the surface of the anterior lobe and periphery of the other *** secretory units in the anterior lobe were more than the lateral lobe.A strong reaction of the secretory cells to the PAS was *** serum levels of the light group also significantly increased compared to the control group(P<0.05).The most histometric changes of the lobes were established in the lateral *** stress resulted in a significant decrease in testosterone levels and transformed prostate *** epithelium and parenchyma to scaffold ratio in the temperature group ***:Maximum and minimum changes in the ventral lobe happened under the ascent of temperature and light,*** ventral lobe in the study of prostatic hyperplasia should be more considered.

关键词： Prostate Heat stress Photoperiod Histology Testosterone Rat

Evaluating the characteristics of geological structures in karst groundwater inflow, Nowsud Tunnel

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Journal of Mountain Science 2024年第10期21卷 3434-3452页

作者： BAYAT Narges SADEGHI Erfan NASSERY hamid reza Department of Minerals and Groundwater Resources Faculty of Earth SciencesShahid Beheshti UniversityEvin AveTehran ***Iran Ministry of Energy Kordestan ExpyTehran ***Iran

Highly permeable geological structures such as dissolution channels, open fractures, and faults create environmental challenges regard to hydrological and hydrogeological aspects of underground construction, often causing significant groundwater inflow during drilling due to the limitations of empirical and analytical methods. This study aims to identify the geological factors influencing water flow into the tunnel. High-flow zones' geological features have been identified and examined for this purpose. According to the geological complexity of the Nowsud tunnel, presence of different formations with different permeability and karstification have led to a high volume of underground inflow water (up to 4700 L/s) to the tunnel. The Nowsud tunnel faces significant geological and hydrogeological challenges due to its passage through the Ilam formation's LI2 unit, characterized by dissolution channels, faults, and fractures. The highest inflow rate (4700 L/s) occurred in the Hz-9 zone within the Zimkan anticline. The relationship between geological features and groundwater inflow indicates that anticlines are more susceptible to inflow than synclines. Additionally, different types of faults exhibit varying hydraulic effects, with strike-slip faults having the most significant impact on groundwater inflow, thrust faults conducting less water into the tunnel, and inflow through normal faults being negligible compared to the other two types of faults. The novelty of this paper lies in its detailed analysis of geological features influencing groundwater inflow into the Nowsud tunnel, providing empirical data on high-flow zones and differentiating the hydraulic effects of various fault types, which enhances the understanding and prediction of groundwater inflow in underground constructions.

关键词： Geological structures Groundwater inflow Hydrogeology Nowsud tunnel Karst

Effect of CO_(2)exposure on the mechanical strength of geopolymerstabilized sandy soils

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第2期16卷 670-681页

作者： hamid reza Razeghi Armin Geranghadr Fatemeh Safaee Pooria Ghadir Akbar A.Javadi School of Civil Engineering Iran University of Science and TechnologyTehran***Iran Department of Engineering University of ExeterExeterEX44QFUK

In recent years,there has been growing interest in developing methods for mitigating greenhouse effect,as greenhouse gas emissions continue to contribute to global temperature *** the other hand,investigating geopolymers as environmentally friendly binders to mitigate the greenhouse effect using soil stabilization has been widely ***,the effect of CO_(2)exposure on the mechanical properties of geopolymer-stabilized soils is rarely *** this context,the effect of CO_(2)exposure on the mechanical and microstructural features of sandy soil stabilized with volcanic ash-based geopolymer was *** factors were concerned,for example the binder content,relative density,CO_(2)pressure,curing condition,curing time,and carbonate *** results showed that the compressive strength of the stabilized sandy soil specimens with 20%volcanic ash increased from 3 MPa to 11 *** was also observed that 100 kPa CO_(2)pressure was the optimal pressure for strength development among the other *** mechanical strength showed a direct relationship with binder content and carbonate ***,in the ambient curing(AC)condition,the mechanical strength and carbonate content increased with the curing ***,the required water for carbonation evaporated after 7 d of oven curing(OC)condition and as a result,the 14-d cured samples showed lower mechanical strength and carbonate content in comparison with 7-d cured ***,the rate of strength development was higher in OC cured samples than AC cured samples until 7 d due to higher geopolymerization and carbonation rate.

关键词： Soil stabilization CO_(2)effect Geopolymer

The Role of Immune System in Depression Disorder

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Health 2016年第15期8卷 1726-1743页

作者： Fatemeh Hoseinzadeh Porya Hassan Abadi Mehdi Agheltar Arvin Aghayinejad Farnaz Torabian Arash Akhavan rezayat Farzad Akbarzadeh hamid reza rahimi Department of Psychiatry School of Medicine Mashhad University of Medical Sciences Mashhad Iran School of Medicine Islamic Azad University of Mashhad Mashhad Iran School of Medicine Islamic Azad University of Mashhad Mashhad Iran Student Research Committee Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran Department of Modern Sciences & Technologies School of Medicine Mashhad University of Medical Sciences Mashhad Iran

In order to diagnose a major depressive disorder, patients must have at least 5 depres-sive symptoms out of 9 criteria, present for at least two weeks. Depressive symptoms include absence of concentration, fatigue and suicidal ideation. The intensity of de-pression symptoms affects the severity of depression and the degree of the impact on the quality of life. Major depressive disorders (MDD) are defined as a significant health problem, and are estimated to rise in prevalence in the future years. Immune cytokine, associated with major depression for instance, is the interleukin IL-6 and tu-mor necrosis factor (TNF-α) which is defined as pro-inflammatory cytokines, can ac-tivate an inflammatory response. The effects of other inflammatory cytokines on the central nervous system are of controversy. There is an increasing interest about the ef-fect of cytokines derived from innate immune system on the brain and behavior. Cytokines are defined as large sized proteins, mainly produced by immune cells. Two subtypes of cytokines exist: pro-inflammatory cytokines, facilitating inflammatory re-sponses and neural activities;and anti-inflammatory cytokines, inhibiting inflammatory processes. Besides microglia and astrocytes, immune cells such as monocytes, macrophages, and lymphocytes also produce cytokines. At the times of immunological alterations, infections or inflammation, cytokines will be in an activated form. The main goal of the current review study is to investigate the role of the immune system in the depression disorder.

关键词： Depression Cytokines IL-6 TNF-α Psychoneuroimmunology

Exploring the relationship between ambient sulfur dioxide and semen quality parameters:A systematic review and meta-analysis

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Asian pacific Journal of Reproduction 2024年第1期13卷 12-21页

作者： Seyed Sobhan Bahreiny Mojtaba Aghaei Mohammad reza Dabbagh hamid Ghorbani Moslem Javidan reza Mohammadpour Fard Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Medical Basic Sciences Research Institute Physiology Research CenterDepartment of PhysiologySchool of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Department of Biology Faculty of ScienceShahid Chamran University of AhvazAhvazIran Department of Immunology Faculty of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran

Objective:To investigate the relationship between ambient sulfur dioxide(SO2)exposure and semen quality ***:A systematic literature search was conducted to identify relevant studies investigating the association between SO2 exposure and semen quality *** search encompassed the timeframe from January 2000 to May 2023 and included electronic databases such as Web of Science,Google Scholar,PubMed,Cochrane,and *** effect estimates with 95%confidence intervals(CI)were calculated using percent changes(PC).The meta-analysis included seven studies with 6711 participants and 15087 semen ***:The results revealed a significant negative association between ambient SO2 exposure and certain semen quality *** particular,SO2 exposure was associated with a significant decrease in progressive motility(PC=0.032;95%CI:-0.063 to-0.001;P=0.044)and sperm concentration(PC=-0.020;95%CI:-0.036 to-0.005;P=0.012).However,no statistically significant associations were observed for total sperm count(PC=-0.038;95%CI:-0.079 to 0.003;P=0.070),seminal fluid volume(PC=-0.009;95%CI:-0.048 to-0.030;P=0.662)and sperm motility(PC=-0.17;95%CI:-0.363 to 0.022;P=0.830).In addition,the results of the subgroup analysis revealed specific variables that were associated with the decrease in relevant sperm ***:This systematic review and meta-analysis provides compelling evidence supporting a consistent negative association between exposure to ambient SO2 and semen quality parameters.

关键词： Semen quality Sulfur dioxide Ambient air pollution Meta-analysis

Hepatoprotective effect of Holothuria leucospilota methanolic extract on dimethyl nitrosamine-induced hepatotoxicity in rats

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Animal Models and Experimental Medicine 2024年第4期7卷 544-552页

作者： Fatemeh Dejan Amineh Daneshi Javad Rajabi Aslani Nasrollah Ahmadi Narges Eskandari Roozbahani Elaham Rahmanian reza Behmanesh hamid reza Gheisari Department of Basic Sciences School of Veterinary MedicineShiraz UniversityShirazIran Department of Education Farzanegan High SchoolTehranKohgiluyeh and Boyer AhmadIran Food Hygiene Department School of Veterinary MedicineShiraz UniversityShirazIran Department of Pathology School of Veterinary MedicineShiraz UniversityShirazIran Clinical Research Development Center Imam Reza HospitalKermanshah University of Medical SciencesKermanshahIran Molecular Dermatology Research Center Shiraz University of Medical SciencesShirazIran Department of Anatomy School of MedicineShiraz University of Medical SciencesShirazIran Faculty of Veterinary Medicine Garmsar BranchDepartment of RadiologyIslamic Azad UniversityGarmsarIran

Background:Complementary medicine is an interesting field for extracting bio-active compounds from various plant and animal *** hepatoprotective effect of the methanolic extract of a species of sea cucumber called Holothuria leu-cospilota in an animal model of liver cancer caused by dimethyl nitrosamine(DMN)was ***:Wistar female rats were randomly divided into five groups(n=12):control(intact),positive control(received 1%DMN[10 mg/kg/week,intraperitoneally]for 12 weeks),and three treatment groups(received 50,100,and 200 mg/kg/day ***-cospilota extract orally for 12 weeks along with intraperitoneal administration of 1%DMN[10 mg/kg/week]).In all groups,ultrasound was performed on the liver every week to check its *** sampling and liver isolation were performed on three occasions,at 4,8,and 12 weeks,to check liver enzymes and the histopathological condition of the liver tissue(every week,four animals from each group were randomly selected).Results:Liver density changes were evident from the eighth week onward in the positive control *** results indicated pathologic changes in the positive control group after 4 *** increase in liver enzymes in the posi-tive control group was significantly different from that in the treatment and control ***:We demonstrated the hepatoprotective effect of *** on DMN-induced liver damage in rats using biochemical and histological parameters and *** additional research(in silico or in vitro)is needed to find the exact mechanism and the main biological compound in ***.

关键词： dimethyl nitrosamine hepatotoxicity Holothuria leucospilota sea cucumber

Correlation between critical thinking and emotional intelligence:a national crosssectional study on operating room nursing students in Iran

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Frontiers of Nursing 2024年第1期11卷 99-104页

作者： Armin Fereidouni Esmaeil Teymoori Tayebeh Bahmani hamid reza Sabet Zahra Maleki Mina Gharibi Department of Operating Room Technology Community Based Psychiatric Care Research CenterSchool of Nursing and MidwiferyShiraz University of Medical SciencesShirazIran Department of Operating Room Technology School of Paramedical SciencesAJA University of Medical SciencesTehranIran Department of Operating Room School of Allied Medical ScienceFasa University of Medical SciencesFasaIran Clinical Education Research Center Shiraz University of Medical SciencesShirazIran Medical Journalism Department School of Paramedical SciencesShiraz University of Medical SciencesShirazIran Department of Epidemiology Student Research CommitteeShiraz University of Medical SciencesShirazIran

Objective:According to the World Federation of Medical Education,critical thinking should be part of the training of medical and paramedical *** can improve the quality of care of patients after surgery by having or acquiring this skill in health ***,Emotional intelligence is introduced as an impor tant and effective factor on the professional performance and mental health of healthcare ***,the present study was designed and implemented to determine the relationship between emotional intelligence and critical thinking among operating room nursing students of medical sciences universities in ***:This cross-sectional study was done on 420 operating room students in 10 top medical sciences universities of Iran in *** sampling method in this research was multistage *** data collection instruments included demographic characteristics,Rickett's critical thinking,and Bradberry-Greaves'emotional intelligence *** receiving the ethics code,data collection was done for 2 *** data analysis,descriptive and inferential analyses including independent t-tests,analysis of variance,and Pearson correlation were *** collected data were analyzed by SPSS 18(IBM Corporation,Armonk,New York,United States).P-value<0.05 was considered ***:The mean age of the students participating in this study was 23.02±3.70 years,with women constituting 67.4%of *** results of data analysis indicated that the mean total score of critical thinking and emotional intelligence was 124.10±37.52 and 114.12±43.63,respectively.A direct significant correlation between critical thinking and emotional intelligence(r=0.459,P-value<0.001)and a significant relationship between gender and emotional intelligence(P-value=0.028)were ***:Based on the present study results,educational managers in the Ministry of Health are suggested to consider suitable educational programs for improving critical think

关键词： critical thinking emotional intelligence operating room students operating room nurses

Antidepressants can treat inflammatory bowel disease through regulation of the nuclear factor-κB/nitric oxide pathway and inhibition of cytokine production:A hypothesis

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2012年第6期3卷 83-85页

作者： hamid reza rahimi Mahdi Shiri Ali Razmi Department of Toxicology and Pharmacology Faculty of Pharmacy and Pharmaceutical Sciences Research Center Tehran University of Medical Sciences Tehran 15614 Iran Pharmacology and Applied Medicine Department of Medicinal Plants Research Center Institute of Medicinal PlantsACECR Karaj 31535 Iran

Inflammatory bowel disease (IBD) is a group of inflammatory disorders mainly affecting the colon and small intestine. The main types of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). UC is restricted to the large intestine whereas CD can affect any part of the gastrointestinal tract. Treating this disorder depends on the form and level of severity. Common treatment involves an anti-inflammatory drug, such as mesalazine, and an immunosuppressant, such as prednisone. Several signaling pathways, including nuclear factor (NF)-κB and nitric oxide (NO), and genetic and environmental factors are believed to play an important role in IBD. Amitriptyline is a commonly used antidepressant with known anti-inflammatory activities. Amitriptyline also acts on the NF-κB/NO pathway or cytokine production. Therefore, we hypothesize that antidepressants like amitriptyline can be pioneered and considered effective as an innovative and effective therapeutic in the treatment and attenuation of development of IBD in adjusted doses.

关键词： Inflammatory bowel disease Crohn’s disease Antidepressant Nuclear factor-κB Nitric oxide