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Clinical and Bacteriological Profile of Infections in Sickle Cell Children in Two Referral Hospitals in Niamey, Niger

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Open Journal of Pediatrics 2024年第1期14卷 36-42页

作者： Kamaye Moumouni Samaila Aboubacar Garba Moumouni Georges Thomas ibrahim Mamoudou Abdou Djafar Mamane Halima hamadou ibrahim Hamani Issaka Djibrilla Almoustapha Amadou Yacouba Abdourahamane Marou Soumana Boubacar Moussa Saley Sahada Bade Malam Abdou Soumana Alido Service de Pédiatrie A H&#244pital National de Niamey Niamey Niger Faculté des Sciences de la Santé Université Abdou Moumouni de Niamey Niamey Niger Service de Pédiatrie H&#244pital national Amirou Boubacar Diallo Niamey Niger Service d’Onco-Hématologie H&#244pital national de Niamey Niamey Niger Service de Biologie Médicale H&#244pital national Amirou Boubacar Diallo Niamey Niger

Introduction: Infections are significant causes of mortality in sickle cell children in resource-limited countries. This study aimed to determine the clinical profile and bacterial ecology of infections in children with sickle-cell disease in two referral hospitals in Niamey. Patients and methods: A retrospective descriptive study was conducted from January 2018 to July 2020 in two referral hospitals in Niamey. All children aged one (1) to 15 years with sickle cell disease admitted for suspected infection, including at least one bacterial culture, were studied. Bacteriological analysis was performed using the appropriate culture media, using BactAlert (Reference 4700003 BTA3D60 BioMérieux). Results: Over 36-months, 350 children with a mean age of 10.9 months were admitted. The sex ratio was 1.2. The SS electrophoretic profile was the most common (93.4%). Immunization status was up to date in 66% of patients. Fever was the common reason for consultation (55.1%). Infection was confirmed in 62 patients (17.7%). The primary diagnoses were bacterial gastroenteritis (24.2%) and urinary tract infection (19.4%). Blood cultures were isolated from Salmonella typhi (13.0%) and Escherichia coli (8.7%). Klebsiella spp (7.1%) and Escherichia coli (5.0%) were detected in cytobacteriological examination of urine. Salmonella typhi (23.5%) and Escherichia coli (5.9%) were isolated on coproculture. Conclusion: Bacterial ecology appears not different from that usually observed in sickle-cell children. Salmonella and Escherichia coli were predominant.

关键词： Sickle Cell Disease Child Infection Niger

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Knowledge of Health Professionals on Essential Newborn Care in Bamako, Mali

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Open Journal of Pediatrics 2018年第4期8卷 311-323页

作者： Fatoumata Dicko Traore Mariam Sylla Hawa Diall Mamadou Traore Pierre Togo Mariam Maiga Nouhoum Lalama Traore Leyla Maiga Kalirou Traore Marikomosse Sacko Souleymane Sagara hamadou ibrahim Oumou Maiga Diakaridia Mariko Saoudatou Tall Oumar Coulibaly Issiaka Kone Modibo Soumare Kadiatou Ba Youssouf Traore Niani Mounkoro Toumani Sidibe Department of Pediatrics CHU Gabriel ToureBamakoMali Reference Health Center of Commune V BamakoMali Reference Health Center of Commune VI BamakoMali Reference Health Center of Commune IV BamakoMali Reference Health Center of Commune III BamakoMali Reference Health Center of Commune I BamakoMali Reference Health Center of Commune II BamakoMali Department of Gynecology and Obstetrics CHU Gabriel ToureBamakoMali

Despite existing policies on training health professionnels in essential newborn care (ENC), neonatal mortality still remains high in Mali. Our work aimed to assess the level of knowledge of health staff about ENC. Material and methods: From March 20th to April 20th, 2016, we interviewed newborn care providers at the six reference health centers and the Gabriel Touré University Hospital Center in Bamako. Results: In total, we interviewed 407 newborn care providers with a sex ratio of 0.52. Interviewees had over five years work experience in 62.1%. They considered a low Apgar score as an indication for neonatal resuscitation in 89%, regardless of profile (p = 0.1583). They knew the good aspiration technique in 54%, with nurses and midwives more knowledgeable (p ) of the reference health centers (p = 0.0000). The interviewees knew the indication and rate of ventilation in 30.2% and 16.0%, respectively. About one third (34%) thought oxygen administration should be systematic during ventilation. The knowledge level on ventilation was the lowest in the group of general practitioners (p = 0.0063 for oxygen indication and p for the technique). Knowledge level for other ENC components (temperature maintenance, eyes care, breastfeeding) were higher. The knowledge of the delay of the breasting did not correlated with either the profile (p = 0.0857) or the place of practice. The knowledge of the first bath was dependent on both the professional profile (p = 0.0002) and the reference level (p = 0.0238). Conclusion: The level of knowledge of health professionnels on ENC should be improved. This will involve the integration of ENC in initial training curricula along with an appropriate continuing training policy thereafter.

关键词： Essential Care Newborn Knowledge Bamako

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Post-Infectious Acute Glomerulonephritis in Child: Epidemiological, Clinical and Evolutionary Aspects in Gabriel TouréTeaching Hospital in Mali

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Open Journal of Pediatrics 2018年第4期8卷 366-374页

作者： Mariam Sylla Fatoumata Dicko-Traoré Abdoul Karim Doumbia Aminata Coulibaly Abdoul Aziz Diakité Modibo Sangaré Pierre Togo Fousseyni Traoré Amadou Touré Djènèba Konaté Karamoko Sacko Belco Maiga Fatoumata Léonie Diakité Lala N’Drainy Sidibé Mohamed Elmouloud Cissé Adama Dembélé Hawa Diall Oumar Coulibaly ibrahim hamadou Leyla Maiga Issiaka Koné Boubacar Togo Toumani Sidibé Department of Pediatrics CHU Gabriel Touré Bamako Mali Faculty of Medecine and Odontostomatology Bamako Mali

Introduction: Acute post-infectious glomerulonephritis (APIGN) can be serious due to its complications that still occur in our countries. In this work, we aimed to study the epidemiological, clinical, biological and evolutionary aspects of APIGN. Patients and methods: We conducted a retrospective, descriptive study from January 1st, 2015 to December 31st, 2017 in the pediatric ward of the Gabriel Touré Teaching Hospital in Bamako. All children hospitalized for APIGN were included. Results: In two years, we included 10 children aged 7 years old on average;all from low socioeconomic backgrounds. The sex ratio was 1.5. On average, the children spent 15.8 days before our consultation. Edema was the main reason for consultation. We found a history of infection and high blood pressure in 30% each, and renal failure in 10% of the children. Hematuria and proteinuria were detected in 100% and 90%, respectively. Hypocomplementemia was observed in 66.6%. One third of the children had a positive antistreptolysin O. The average duration of hospital stay was 11.2 days. The evolution was favorable in 90%. Kidney failure was the leading cause of death. Conclusion: Acute post-infectious glomerulonephritis is still a reality in our context. Emphasis should be put on its prevention by improving the hygienic conditions, detection and the management of infections.

关键词： Glomerulonephritis Infection Pediatrics Mali

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