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Association between psychological distress and gastrointestinal symptoms in diabetes mellitus

World Journal of Diabetes 2012年第6期3卷 123-129页

作者： Abdulbari Bener Suhaila Ghuloum Abdulla OAa.al-Hamaq Elnour E Dafeeah Department of Medical Statistics and Epidemiology Hamad Medical CorporationDohaPO Box 3050Qatar Department of Public Health Weill Cornell Medical CollegeDohaPO Box 3050Qatar Department of Evidence for Population Health Unit School of Epidemiology and Health SciencesUniversity of ManchesterManchesterM13 9PLUnited Kingdom Department of Psychiatry Psychology UnitRumailah HospitalHamad Medical CorporationDohaPO Box 3050Qatar Qatar Diabetic Associations and Qatar Foundation DohaPO Box 5825Qatar

AIM:To examine the possible association between gastrointestinal symptoms and anxiety and depression in type 2 diabetes mellitus(T2DM).METHODS:The study was a matched case-control study based on a face to face interview with designed diagnostic screening questionnaires for gastrointestinal(GI) symptoms and T2DM,Patient Health Questionnaire(PHQ-9) for depression and General Anxiety Disorders(GAD-7) for *** questionnaire consisted of questions about symptoms and signs of anxiety and depression ***,socio-demographic characteristics,life style habits and the family history of patients were *** was carried out from June 2010 to May 2011 among Qatari and other Arab nationals over 20 years of age at Primary Health Care Centers of the Supreme Council of Health,Qatar,including patients with diabetes mellitus and healthy subjects over 20 years of ***:In the studied sample,most of the studied T2DM patients with GI symptoms(39.3%) and healthy subjects(33.3%) were in the age group 45-54 years(P alence of severe depression(9.5% vs 4.4%,P al ***(35.7% vs 31.2%) and being overweight(47.9% vs 42.8%) were significantly higher in T2DM patients with GI symptoms than in healthy subjects(P = 0.001).Mental health severity score was higher in T2DM patients with GI symptoms than in healthy subjects;depression(8.2 ± 3.7 vs 6.0 ± 3.6) and anxiety(7.6 ± 3.3 vs 6.0 ± 3.7).The most significant GI symptom which was considerably different from controls was early satiety [odds ratio(OR) = 10.8,P = 0.009] in depressed T2DM patients and loose/watery stools(OR = 2.79,P = 0.029) for severe *** was observed more than depression in T2DM patients with GI ***:Gastrointestinal symptoms were significantly associated with depression and anxiety in T2DM patients,especially anxiety disorders.

关键词： Gastrointestinal Type 2 diabetes mellitus Distress Depression Anxiety Qatar

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Parental transmission of type 2 diabetes mellitus in a highly endogamous population

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World Journal of Diabetes 2013年第2期4卷 40-46页

作者： Abdulbari Bener Mohammad T Yousafzai Abdulla OAa.al-Hamaq Abdul-Ghani Mohammad Ralph A DeFronzo Department of Medical Statistics and Epidemiology Hamad Medical Corporation Department of Evidence for Population Health Unit School of Epidemiology and Health Sciences The University of Manchester Qatar Diabetic Association and Qatar Foundation Division of Diabetes University of Texas Health Science Center at San Antonio

AIM: To determine the parental transmission of diabetes mellitus (DM) and evaluate its influence on the clinical characteristics. METHODS: This was a cross sectional study. The survey was carried out in urban and semi-urban primary health care centers. Of the 2400 registered with diagnosed diabetes, 1980 agreed and gave their consent to take part in this study, thus giving a response rate of 82.5%. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. DM was defined according to the World Health Organization expert group. A trained nurse performedphysical examinations and measurements. RESULTS: Of the study population, 72.9% reported a family history of DM. Family history of DM was significantly higher in females (54.2%; P = 0.04) and in the age group below 30 years (24%; P alence of diabetes was higher among patients with a diabetic mother (25.4% vs 22.1%) and maternal aunts/uncles (31.2% vs 22.2%) compared to patients with a diabetic father and paternal aunts/ uncles. Family history of DM was higher in patients of consanguineous parents (38.5%) than those of non-consanguineous parents (30.2%). The development of type 2 diabetes mellitus (T2DM) complications was higher in patients with either a paternal or maternal history of DM than in those without. No significant difference was observed in the metabolic characteristics of patients with/without family history of DM except for hypertension. Complications were higher in diabetic patients with a family history of DM. CONCLUSION: The present study found a significant maternal effect in transmission of T2DM. Family history is associated with the increased incidence of diabetes.

关键词： Diabetes mellitus Family history Parental transmission Genetic disorders Consanguinity Maternal transmission

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Multi-modality imaging review of congenital abnormalities of kidney and upper urinary tract

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World Journal of Radiology 2016年第2期8卷 132-141页

作者： Subramaniyan Ramanathan Devendra Kumar Maneesh Khanna Mahmoud al Heidous Adnan Sheikh Vivek Virmani Yegu Palaniappan Department of Clinical Imaging Al-Wakra Hospital Hamad Medical Corporation Department of Medical Imaging the Ottawa Hospital Department of Radiology Dr.Everett Chalmers Hospital Shree Meenakshi Multi Specialty Hospital

Congenital abnormalities of the kidney and urinary tract(CAKUT) include a wide range of abnormalities ranging from asymptomatic ectopic kidneys to life threatening renal agenesis(bilateral). Many of them are detected in the antena.al or immediate postna.al with a significant proportion identified in the adult population with varying degree of severity. CAKUT can be classified on embryological basis in to abnormalities in the renal parenchymal development, aberrant embryonic migration and abnormalities of the collecting system. Renal parenchymal abnormalities include multi cystic dysplastic kidneys, renal hypoplasia, number(agenesis or supernumerary), shape and cystic renal diseases. Aberrant embryonic migration encompasses abnormal location and fusion anomalies. Collecting system abnormalities include duplex kidneys and Pelvi ureteric junction obstruction. Ultrasonography(US) is typically the first imaging performed as it is easily available, noninvasive and radiation free used both antena.ally and postna.ally. Computed tomography(CT) and magnetic resonance imaging(MRI) are useful to confirm the ultrasound detected abnormality, detection of complex malformations, demonstration of collecting system and vascular anatomy and more importantly for early detection of complications like renal calculi, infection and malignancies. As CAKUT are one of the leading causes of end stage renal disease, it is important for the radiologists to be familiar with the varying imaging appearances of CAKUT on US, CT and MRI, thereby helping in prompt diagnosis and optimal management.

关键词： Congenital abnormalities Kidney Urinary tract Multi cystic dysplastic Kidneys Pelvi ureteric junction obstruction Computed tomography urography Congenital abnormalities of the Kidney and urinary tract End stage renal disease Horse shoe Kidneys

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2021亚太心脏病学会P2Y12受体拮抗剂应用于亚太特殊人群的共识

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中华心血管病杂志 2023年第1期51卷 19-31页

作者： Jack Wei Chieh Tan Derek P Chew Kin Lam Tsui Doreen Tan Dmitry Duplyakov Ayman Hammoudeh 张波李毅徐凯 Paul J Ong DoniFirman Habib Gamra Wael almahmeed Jamshed Da.al Lihua Tan Gabriel Steg Quang N Nguyen Junya Ako Jassim al Suwaidi Mark Chan Mohamed Sobhy Abdulla Shehab Wacin Buddhari 王祖禄 alan Yean Yip Fong Bilgehan Karadag Byeong-Keuk Kim Usman Baber Chee Tang Chin 韩雅玲新加坡国立心脏中心新加坡盛港综合医院澳大利亚弗林德斯大学医学与公共卫生学院香港特别行政区东区尤德夫人那打素医院新加坡国立大学理学院药学系俄罗斯萨马拉地区心脏病医院约旦安曼Istishari医院心脏病科大连医科大学第一附属医院心内科大连116000 北部战区总医院心内科沈阳110840 新加坡伊丽莎白诺维娜医院新加坡陈笃生医院印度尼西亚Harapan Kita国家心血管中心、印度尼西亚大学医学院心脏病学和血管医学系突尼斯Fattouma Bourguiba大学医院/莫纳斯提尔大学心脏病科阿拉伯联合酋长国阿布扎比克利夫兰诊所印度孟买Kokilaben Dhirubhai Ambani医院心脏中心香港特别行政区广华医院法国巴黎比夏医院心脏病科越南河内医科大学心脏病科日本神奈川县相模原市北里大学医学院心血管内科卡塔尔多哈哈马德医疗公司成人心脏病科新加坡国立大学心脏中心埃及亚历山大大学医学院阿拉伯联合酋长国阿联酋大学医学与健康科学学院泰国曼谷朱拉隆功国王纪念医院马来西亚砂拉越哥打三马拉汉心脏中心土耳其伊斯坦布尔大学-Cerrahpasa医学院韩国首尔延世大学医学院Severance心血管医院心脏病科美国俄克拉荷马大学健康科学中心

高龄、糖尿病(DM)和慢性肾脏疾病(CKD)不仅会增加慢性冠状动脉综合征(CCS)患者缺血事件的风险,还会增加其接受抗血小板治疗期间的出血风险。此类特殊人群可能需要调整治疗方案,尤其是亚洲的特殊人群,往往表现出与西方人群不同的临床特... 详细信息

高龄、糖尿病(DM)和慢性肾脏疾病(CKD)不仅会增加慢性冠状动脉综合征(CCS)患者缺血事件的风险,还会增加其接受抗血小板治疗期间的出血风险。此类特殊人群可能需要调整治疗方案,尤其是亚洲的特殊人群,往往表现出与西方人群不同的临床特征。关于亚洲人群CCS高风险的分类和急性冠状动脉综合征(ACS)后使用新一代强效P2Y12受体抑制剂(如替格瑞洛和普拉格雷)的国际指南已相继发表。本共识总结了在特殊人群中使用强效P2Y12受体抑制剂的相关证据,提出了在冠状动脉疾病(CAD)特殊人群中应用标准疗程双联抗血小板治疗(DAPT)、短期DAPT和单一抗血小板治疗的推荐意见。本共识的特殊人群包括从ACS过渡至CCS,老年,或患有CKD、DM、多血管CAD和治疗期间发生出血并发症等特征的患者。

关键词：血小板聚集抑制剂亚洲心肌缺血共识双联抗血小板治疗

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Methods for a blind a.alysis of isobar data collected by the STAR collaboration

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Nuclear Science and Techniques 2021年第5期32卷 43-50页

作者： J.Adam L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderon de la Barca Sanchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanad M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal X.Gou D.Grosnick W.Guryn A.I.hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He Y.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.Ji J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana M.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan M.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev M.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga Mudiyanselage L.Kumar S.Kumar R.Kunna.alkam Elaya.alli J.H.Kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Md.Nasim K.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonak Christian University AbileneTX 796992 AGH University of Science and Technology FPACSCracow 30-059Poland alikhanov Institute for Theoretical and Experimental Physics NRC"Kurchatov Institute" MoscowRussia 117218 Argonne National Laboratory ArgonneIL 60439 American University of Cairo New CairoNew Cairo 11835Egypt Brookhaven National Laboratory UptonNY 11973 University of California BerkeleyCA 94720 University of California DavisCA 95616 University of California Los AngelesCA 90095 University of California RiversideCA 92521 Central China Normal University Wuhan 430079 University of Illinois at Chicago ChicagoIL 60607 Creighton University OmahaNE 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universitat Darmstadt Darmstadt 64289Germany ELTE Eotvos Lorand University Budapest 1117Hungary Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg 69120 HeidelbergGermany University of Houston HoustonTX 77204 Huzhou University Huzhou 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIN 47408 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research DubnaRussia 141980 Kent State University KentOH 44242 University of Kentucky LexingtonKY 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCA 94720 Lehigh University BethlehemPA 18015 Max-Planck-Institut fur Physik 80805 MunichGermany Michigan State University East LansingMI 48824 National Research Nuclear University MEPhI MoscowRussia 115409 National Institute of Science Education and Research HBNIJatni 752050India National Cheng Kung University Tainan 70101 Nuclear Physics Institute of the CAS Rez 25068Czech Republic Ohio State University

In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of *** isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)*** order to conduct blind a.alyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind a.alysis *** are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run *** tuning a.alysis codes and performing time-dependent quality assurance on the reference sample,a.alysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking *** this sample,species-specific information is disguised,but individual output files contain data from a single isobar *** run-by-run corrections and code alteration subsequent to these corrections are allowed at this *** these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind *** a check of the feasibility of the blind a.alysis procedure,a.alysts completed a"mock data challenge,"a.alyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in *** Au+Au data were prepared in the same manner intended for the isobar blind *** details of the blind a.alysis procedure and results from the mock data challenge are presented.

关键词： Blind a.alysis Chiral magnetic effect Heavy-ion collisions

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Measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √sNN=200 GeV

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Chinese Physics C 2020年第10期44卷 59-67页

作者： L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderón de la Barca Sánchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanád M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal D.Grosnick W.Guryn A.I.hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.JI J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana M.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan M.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev M.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga Mudiyanselage L.Kumar S.Kumar R.Kunna.alkam Elaya.alli J.H.Kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Nasim Md K.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa Abilene Christian University AbileneTexas 79699 AGH University of Science and Technology FPACSCracow 30-059Poland alikhanov Institute for Theoretical and Experimental Physics NRC"Kurchatov Institute" Moscow 117218Russia Argonne National Laboratory ArgonneIllinois 60439 American University of Cairo New Cairo 11835New CairoEgypt Brookhaven National Laboratory UptonNew York 11973 University of California BerkeleyCalifornia 94720 University of California DavisCalifornia 95616 University of California Los AngelesCalifornia 90095 University of California RiversideCalifornia 92521 Central China Normal University WuhanHubei 430079 University of Illinois at Chicago ChicagoIllinois 60607 Creighton University OmahaNebraska 68178 Czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universität Darmstadt Darmstadt 64289Germany ELTE Eötvös Loránd University BudapestHungary H-1117 Frankfurt Institute for Advanced Studies FIAS Frankfurt 60438Germany Fudan University Shanghai 200433 University of Heidelberg Heidelberg 69120Germany University of Houston HoustonTexas 77204 Huzhou University HuzhouZhejiang 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIndiana 47408 Institute of Modern Physics Chinese Academy of SciencesLanzhouGansu 730000 University of Jammu Jammu 180001India Joint Institute for Nuclear Research Dubna 141980Russia Kent State University KentOhio 44242 University of Kentucky LexingtonKentucky 40506-0055 Lawrence Berkeley National Laboratory BerkeleyCalifornia 94720 Lehigh University BethlehemPennsylvania 18015 Max-Planck-Institut für Physik Munich 80805Germany Michigan State University East LansingMichigan 48824 National Research Nuclear University MEPhI Moscow 115409Russia National Institute of Science Education and Research HBNIJatni 752050Indi

High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion *** of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic *** report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR *** correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5al heavy-ion collisions.

关键词： di-hadron correlations jet heavy-ion

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