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Frequency,types,and treatment of anemia in Turkish patients with inflammatory bowel disease

World Journal of Gastroenterology 2018年第36期24卷 4186-4196页

作者： Goksel Bengi Hatice Keyvan Seda Bayrak Durmaz hale akpinar Division of Gastroenterology Department of Internal MedicineFaculty of MedicineDokuz Eylul UniversityIzmir 35360Turkey Department of Internal Medicine Faculty of MedicineDokuz Eylul UniversityIzmir 35360Turkey

AIM to specify the type and prevalence of anemia along with a treatment approach for inflammatory bowel disease(IBD).METHODS We conducted a retrospective study on 465 patients who were diagnosed with IBD and followed up at our hospital from June 2015 to June 2016 [male: 254, female: 211; average age: 47 ± 14.4; Crohn's disease(CD): 257, Ulcerative Colitis(UC): 208]. Epidemiological and clinical data, such as sex, age, age of diagnosis, type of IBD, disease extension, disease behavior and duration, treatments for IBD and anemia, and surgical history were obtained for each patient. Per World Health Organization guidelines, anemia was diagnosed for males if hemoglobin values were less than 13 g/dL and for females if hemoglobin values were less than 12 g/d *** We determined that 51.6% of the patients had anemia, which was more frequent in women then men(64% vs 41.3%, P < 0.001). Anemia frequency was higher in CD cases(57.6%) than in UC cases(44.2%)(P = 0.004). CD involvements were as follows: 48.2% in ileal involvement, 19% in colonic involvement, and 32.8% in ileocolonic involvement. Furthermore, 27.5% of UC patients had proctitis(E1) involvement, 41% ofthem had involvement in left colitis(E2), and 31.5% had pancolitis involvement. There was no significant relationship between anemia frequency and duration of disease(P = 0.55). Iron deficiency anemia(IDA) was the most common type of anemia in this cohort. Moreover, because anemia parameters have not been evaluated during follow-up of 15.3% of patients, the etiology of anemia has not been clarified. Fifty percent of patients with anemia received treatment. Twentythree percent of IDA patients had oral iron intake and forty-one percent of IDA patients had parenteral iron treatment. Fifty-three percent of patients who were suffering from megaloblastic anemia received B12/folic acid *** We found out that almost half of all IBD patients(51.6%) had anemia, the most frequent of which was IDA. Almost half

关键词： Anemia Inflammatory bowel disease Anemia of iron deficiency

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Effectiveness of Saccharomyces boulardii in a rat model of colitis

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World Journal of Gastroenterology 2012年第44期18卷 6452-6460页

作者： Mujde Soyturk Saba Mukaddes Saygili Huseyin Baskin Ozgul Sagol Osman Yilmaz Fatih Saygili hale akpinar Department of Gastroenterology Dokuz Eylul University School of MedicineInciraltiIzmir 35340Turkey Department of Internal Medicine Mediguven HospitalSalihli 45300ManisaTurkey Department of Clinical Microbiology Dokuz Eylul University School of MedicineInciraltiIzmir 35340Turkey Department of Pathology Dokuz Eylul University School of MedicineInciraltiIzmir 35340Turkey Department of Laboratory Animal Science Dokuz Eylul University School of MedicineInciraltiIzmir 35340Turkey Department of Gastroenterology Pamukkale University School of MedicineDenizli 20070Turkey

AIM:To investigate the effects of Saccharomyces boulardii(***) in an experimental rat model of trinitrobenzene sulfonic acid(TNBS)-induced ***:Thirty-two Wistar albino female rats were categorized into five *** the first day of the study,50 mg TNBS was administered via a rectal catheter in order to induce colitis in all rats,except those in the control *** 14 d,the rats were fed a standard diet,without the administration of any additional supplements to either the control or TNBS groups,in addition to 1 mg/kg per day *** to the *** group,1 mg/kg per day methyl prednisolone(MP) to the MP *** animals in the *** + MP group were coadministered these doses of *** and *** the study,weight loss,stool consistency,and the presence of obvious blood in the stool were evaluated,and the disease activity index(DAI) for colitis was *** intestines were examined and colitis was macro-and microscopically *** serum and tissue levels of tumor necrosis factor-α(TNF-α) and nitric oxide(NO) were determined,and fungemia was evaluated in the blood ***:The mean DAI scores for the MP and *** + MP groups was significantly lower than the TNBS group(3.69 ± 0.61 vs 4.46 ± 0.34,P = 0.018 and 3.77 ± 0.73 vs 4.46 ± 0.34,P = 0.025,respectively).While no significant differences between the TNBS and the *** or MP groups could be determined in terms of serum NO levels,the level of serum NO in the *** + MP group was significantly higher than in the TNBS and *** groups(8.12 ± 4.25 μmol/L vs 3.18 ± 1.19 μmol/L,P = 0.013;8.12 ± 4.25 μmol/L vs 3.47 ± 1.66 μmol/L,P = 0.012,respectively).The tissue NO levels in the ***,MP and *** + MP groups were significantly lower than the TNBS group(16.62 ± 2.27 μmol/L vs 29.72 ± 6.10 μmol/L,P = 0.002;14.66 ± 5.18 μmol/Lvs 29.72 ± 6.10 μmol/L,P = 0.003;11.95 ± 2.34 μmol/Lvs 29.72 ± 6.10 μmol/L,P = 0.002,respectively).The tis

关键词： Saccharomyces boulardii Rat Trinitroben-zene sulfonic acid Tumor necrOsis factor-m Nitric ox-ide Fungemia

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艺术博物馆空间的阈限性与社交潜能

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艺术设计研究 2024年第3期 84-93页

作者：周术乔纳森·黑尔烟台大学建筑学院英国诺丁汉大学工程学院建筑与建成环境系

在网络城市公共空间持续阈限和公共生活缺失的现实下,本文以阈限理论为框架,梳理了艺术博物馆从“时间阈限”到“空间阈限”的历史演化过程,及其分别在精神和身体层面的社交潜能。并以三个具有空间阈限性的当代艺术博物馆为例,分析了介... 详细信息

在网络城市公共空间持续阈限和公共生活缺失的现实下,本文以阈限理论为框架,梳理了艺术博物馆从“时间阈限”到“空间阈限”的历史演化过程,及其分别在精神和身体层面的社交潜能。并以三个具有空间阈限性的当代艺术博物馆为例,分析了介于“结构/反结构”“公共/私密”之间的空间布局和形态特征,指出其设计核心是为了弱化物质空间的存在,从而释放新的社交可能性。

关键词：艺术博物馆空间阈限性社交潜能

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FIXED-POINT CONTINUATION APPLIED TO COMPRESSED SENSING:IMPLEMENTATION AND NUMERICAL EXPERIMENTS

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Journal of Computational Mathematics 2010年第2期28卷 170-194页

作者： Elaine T.hale Department of Computational and Applied Mathematics Rice University

Fixed-point continuation （FPC） is an approach, based on operator-splitting and continuation, for solving minimization problems with l1-regularization：min ｜｜x｜｜1＋uf（x）.We investigate the application of this algorithm to compressed sensing signal recovery, in which f（x） = 1/2｜｜Ax-b｜｜2M,A∈m×n and m≤n. In particular, we extend the original algorithm to obtain better practical results, derive appropriate choices for M and u under a given measurement model, and present numerical results for a variety of compressed sensing problems. The numerical results show that the performance of our algorithm compares favorably with that of several recently proposed algorithms.

关键词： l1 regularization Fixed-point algorithm Continuation Compressed sensing,Numerical experiments.

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Decay threshold of acetylated rattan (Calamus manan) against soft rot

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Journal of Forestry Research 2013年第2期24卷 375-380页

作者： Norul Hisham Hamid Mike hale Department of Forest Production Faculty of Forestry University Putra of Malaysia School of Environment Natural Resources and Geography Bangor University

We investigated the resistance of acetylated rattan against soft rot and other soil inhabiting micro-organisms in comparison with wood of beech and Scots pine. Calamus manan of 10 and 13 years old under rubber tree canopy was acetylated to different levels by reaction times （0.25 to 30 hours） and was tested for soft rot decay for 32 weeks. Acetylated rattan at decay protection thresholds of 15.4% and 16.2% weight gain （WG） were fully protected, as shown by both weight loss and strength loss criteria. The static bending properties of untreated rattan decayed by soft rot were significantly lower than for acetylated rattan.

关键词： acetylation cultivated rattan soft rot static bending properties

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Chebfun and numerical quadrature

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Science China Mathematics 2012年第9期55卷 1749-1760页

作者： hale Nicholas TREFETHEN Lloyd N Mathematical Institute University of OxfordOxford OX1 3LBUK

Chebfun is a Matlab-based software system that overloads Matlab's discrete operations for vectors and matrices to analogous continuous operations for functions and *** begin by describing Chebfun's fast capabilities for Clenshaw-Curtis and also Gauss-Legendre,-Jacobi,-Hermite,and-Laguerre quadrature,based on algorithms of Waldvogel and Glaser,Liu and *** we consider how such methods can be applied to quadrature problems including 2D integrals over rectangles,fractional derivatives and integrals,functions defined on unbounded intervals,and the fast computation of weights for barycentric interpolation.

关键词： Chebfun Clenshaw-Curtis quadrature Gauss quadrature barycentric interpolation formula Riemann-Liouville integral fractional calculus

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Electro-Optics and Band Gap Energies of Nanosilver-Coated TiO2 Nanotubes on Titanium Metal

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Acta Metallurgica Sinica(English Letters) 2018年第2期31卷 153-163页

作者： Ugursoy Olgun Mustafa Gülfen Fatih Ustel hale Arslan Department of Chemistry Faculty of Arts and Sciences Sakarya University 54187 Sakarya Turkey Department of Metallurgical and Materials Engineering Faculty of Engineering Sakarya University 54187 Sakarya Turkey

TiO2 nanotubes on Ti metal surface were prepared by the electrochemical anodization method. Then, nanosilver was deposited onto the nanotubes by the electroless dip coating and the anodization. The obtained TiO2 nanotubes were examined by using scanning electron microscopy, atomic force microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, cyclic voltammetry, and UV–Vis. The electrochemical band gap（Eg^CV） of the nanosilver-coated TiO2 nanotubes prepared by the anodization was found as 1.54 eV. Using the UV–Vis measurements, the optical band gap energy（Eg^op.） was calculated as 1.51 eV for the Ag/TiO2 nanotubes obtained by electroless dip coating. The electrical conductivity of the TiO2 nanotubes also increased from 3.0 × 10^-4 to 34.7 S/cm after nano Ag deposition by the anodization *** Ag/TiO2 nanotubes with low band gap and high electrical conductivity are desirable for the applications in electronics, Li-ion batteries, and solar cells.

关键词： Electrochemical anodization TiO2 nanotubes Nano Ag deposition Band gap energy Electrical conductivity

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Small and Medium Enterprises and Global Risks: Evidence from Manufacturing SMEs in Turkey

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International Journal of Disaster Risk Science 2020年第1期11卷 59-73页

作者： Ali Asgary Ali Ihsan Ozdemir hale Ozyürek Disaster and Emergency Management School of Administrative StudiesYork UniversityTorontoON M3J 1P3Canada Business Administration Department Business SchoolAnkara Yildirim Beyazit UniversityEsenboga CampusAnkaraTurkey KOSGEB(Small and Medium Industry Development Organization) AnkaraTurkey

This study investigated how small and medium enterprises(SMEs) in a country perceive major global risks. The aim was to explore how country attributes and circumstances affect SME assessments of the likelihood,impacts, and rankings of global risks, and to find out if SME risk assessment and rankings differ from the global rankings. Data were gathered using an online survey of manufacturing SMEs in Turkey. The results show that global economic risks and geopolitical risks are of major concern for SMEs, and environmental risks are at the bottom of their ranking. Among the economic risks, fiscal crises in key economies and high structural unemployment or underemployment were found to be the highest risks for the SMEs. Failure of regional or global governance, failure of national governance, and interstate conflict with regional consequences were found to be among the top geopolitical risks for the SMEs. The SMEs considered the risk of largescale cyber-attacks and massive incident of data fraud/theft to be relatively higher than other global technological *** social instability and failure of urban planning were among the top societal risks for the SMEs. Although the global environmental and disaster risks were ranked lowest on the list, man-made environmental damage and disasters and major natural hazard-induced disasters were ranked the highest among this group of risks. Overall, the results show that SMEs at a country level, for example Turkey, perceive global risks differently than the major global players.

关键词： Global risks Risk assessment Risk matrix Small and medium enterprises Turkey

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Patterns of climber distribution in temperate forests of the Americas

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Journal of Plant Ecology 2016年第6期9卷 724-733页

作者： Annik Schnitzler Javier Amigo Brack hale Christophe Schnitzler Laboratoire Interdisciplinaire des Environnements Continentaux(LIEC) UMR 7360 Universitéde LorraineMetzFrance Laboratorio de Botánica Facultad de FarmaciaUniversidad de Santiago de CompostelaA CoruñaSpain Franklin University Switzerland SorengoSwitzerland Facultédes Sciences du Sport UnistraUniversitéde StrasbourgStrasbourgFrance

Aims and Methods We propose a standard protocol at the landscape to continental scale for examining to what extent the range of ecological conditions found in temperate latitudes explains the variations in climber species richness and *** protocol was tested in forests of the two *** data set included 151 climber *** selected four categorical traits and grouped these species into six clusters with regard to these *** records of American forests were first gathered into alliances,second combined with bioclimatic indices(rainfall,temperature,continentality).We obtained a total of 59 vegetational units in which we calculated values of climber species richness and proportion of *** units were ultimately gathered into five forest formations(characterized by leaf longevity).Wetlands and uplands were considered *** Findings Our results emphasize clear trends in large-scale patterns of climber distribution,independently of *** species richness(in particular woody climbers)peaks in moist and warm upland forests with oceanic climates,and where conifers are *** flooded areas,climber richness is also very high and peaks in seasonally flooded large *** ecological conditions of frost,dryness or lack of nutrients,climber species richness,abundance and trait diversity decline,resulting in the dominance of small,twining and deciduous life traits.

关键词： American forest bioclimatic indices climber life traits standart protocol species richness

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Capsule endoscopy:Current practice and future directions

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World Journal of Gastroenterology 2014年第24期20卷 7752-7759页

作者： Melissa F hale Reena Sidhu Mark E McAlindon Department of Gastroenterology Royal Hallamshire HospitalSheffield S10 2JFUnited Kingdom

Capsule endoscopy (CE) has transformed investigation of the small bowel providing a non-invasive, well tolerated means of accurately visualising the distal duodenum, jejunum and ileum. Since the introduction of small bowel CE thirteen years ago a high volume of literature on indications, diagnostic yields and safety profile has been presented. Inclusion in national and international guidelines has placed small bowel capsule endoscopy at the forefront of investigation into suspected diseases of the small bowel. Most commonly, small bowel CE is used in patients with suspected bleeding or to identify evidence of active Crohn’s disease (CD) (in patients with or without a prior history of CD). Typically, CE is undertaken after upper and lower gastrointestinal flexible endoscopy has failed to identify a diagnosis. Small bowel radiology or a patency capsule test should be considered prior to CE in those at high risk of strictures (such as patients known to have CD or presenting with obstructive symptoms) to reduce the risk of capsule retention. CE also has a role in patients with coeliac disease, suspected small bowel tumours and other small bowel disorders. Since the advent of small bowel CE, dedicated oesophageal and colon capsule endoscopes have expanded the fields of application to include the investigation of upper and lower gastrointestinal disorders. Oesophageal CE may be used to diagnose oesophagitis, Barrett’s oesophagus and varices but reliability in identifying gastroduodenal pathology is unknown and it does not have biopsy capability. Colon CE provides an alternative to conventional colonoscopy for symptomatic patients, while a possible role in colorectal cancer screening is a fascinating prospect. Current research is already addressing the possibility of controlling capsule movement and developing capsules which allow tissue sampling and the administration of therapy.

关键词： Capsule endoscopy Small bowel Indications Technology Oesophageal Colon

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