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Journal of Biosciences and Medicines 2016年第12期4卷 126-131页

作者： Laila Essabar hajar Rghouda Saloua Dahri Layachi Chabraoui Latifa Chat Yamna Kriouile Departement of General Pediatric II-Pediatric Neurology Unit Rabat Children’s Hospital Rabat Morocco Central Laboratory of Clinical Biochemistry Hospital Ibn Sina Rabat Morocco Departement of Pediatric Radiology Rabat Children’s Hospital Rabat Morocco

Cystic duct cysts are rare lesions, and type VI of TODANI’s modified classification is the rarest subtype with only sporadic case reports in the literature. The following report describes the coexistence of this entity and type 1 tyrosinemia in a one month-old infant referred to our department for etiological investigations of prolonged neonatal cholestasis. To the best of our knowledge, we report herein the first case in the literature describing this association. Cystic duct abnormalities should be considered in the differential diagnosis of neonatal cholestases, however further investigations should be performed to exclude associated life-threatening conditions such as metabolic disorders including tyrosinemia.

关键词： Cystic Duct Choledochal Cyst Tyrosinemia Cholestasis NTBC Neonate

The Modification of Poly amidoamine (PAMAM-G0.5) by Cytosine

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Engineering（科研） 2012年第10期4卷 103-105页

作者： Omid Louie Abdolhossien Massoudi Hooshang Vahedi hajar Asadi Sami Sajjadifar Chemistry Department Payame Noor University Mashhad Iran

The half generation Poly(amidoamine) (PAMAM) dendrimers was synthesized and characterized and modification by heterocyclic DNA base (Cytosine) . The conjugated Cytosine? modified detected by FT-IR, 1H NMR, 13C NMR and... 详细信息

关键词： Component Polyamidoamine PAMAM Cytosine

An Online Malicious Spam Email Detection System Using Resource Allocating Network with Locality Sensitive Hashing

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Journal of Intelligent Learning Systems and Applications 2015年第2期7卷 42-57页

作者： Siti-hajar-Aminah Ali Seiichi Ozawa Junji Nakazato Tao Ban Jumpei Shimamura Graduate School of Engineering Kobe University Kobe Japan National Institute of Information and Communications Technology (NICT) Tokyo Japan Clwit Inc. Tokyo Japan

In this paper, we propose a new online system that can quickly detect malicious spam emails and adapt to the changes in the email contents and the Uniform Resource Locator (URL) links leading to malicious websites by updating the system daily. We introduce an autonomous function for a server to generate training examples, in which double-bounce emails are automatically collected and their class labels are given by a crawler-type software to analyze the website maliciousness called SPIKE. In general, since spammers use botnets to spread numerous malicious emails within a short time, such distributed spam emails often have the same or similar contents. Therefore, it is not necessary for all spam emails to be learned. To adapt to new malicious campaigns quickly, only new types of spam emails should be selected for learning and this can be realized by introducing an active learning scheme into a classifier model. For this purpose, we adopt Resource Allocating Network with Locality Sensitive Hashing (RAN-LSH) as a classifier model with a data selection function. In RAN-LSH, the same or similar spam emails that have already been learned are quickly searched for a hash table in Locally Sensitive Hashing (LSH), in which the matched similar emails located in “well-learned” are discarded without being used as training data. To analyze email contents, we adopt the Bag of Words (BoW) approach and generate feature vectors whose attributes are transformed based on the normalized term frequency-inverse document frequency (TF-IDF). We use a data set of double-bounce spam emails collected at National Institute of Information and Communications Technology (NICT) in Japan from March 1st, 2013 until May 10th, 2013 to evaluate the performance of the proposed system. The results confirm that the proposed spam email detection system has capability of detecting with high detection rate.

关键词： Malicious Spam Email Detection System Incremental Learning Resource Allocating Network Locality Sensitive Hashing

What Impact Does COVID-19 Have in Cirrhotics?

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Open Journal of Gastroenterology 2021年第1期11卷 16-27页

作者： Hakima Abid hajar Cherkaoui Maria Lahlali Nada Lahmidani Mohammed El Abkari Sidi Adil Ibrahimi Department of Hepato-gastroenterology Hassan II University Hospital Fez Morocco Faculty of Medicine and Pharmacy of Fez University of Sidi Mohammed Ben Abdellah Fez Morocco

SARS-Cov-2 is a novel coronavirus discovered in Wuhan, China in late 2019 and responsible for respiratory distress. Aim: study the impact of COVID-19 among patients with cirrhosis. Patients and methods: We conducted a prospective study for a period of 9 months (April 1st-December 1st) that included cirrhotic patients infected with SARS-Cov-2 followed in the gastroenterology department in the University Hospital Hassan II. Results: Among 1437 patients hospitalised for SARS-Cov-2, 8 cirrhotic patients were included in a period of 9 months (April 1st-December 1st). The mean age is 55 y/o and most are female (n = 6). The aetiology of cirrhosis is mostly HCV (n = 3), HBV (n = 2). Half of the infected patients had acute bleeding (one of them had hepatic encephalopathy) and one patient had respiratory distress. Most of the patients had a negative PCR at the end of the hospital stay (n = 5). The mortality rate was 25% and patients were followed up for a period of 4 months. Conclusion: In the studied population, clinical manifestations were essentially a decompensation of cirrhosis.

关键词： SARS-Cov-2 Cirrhosis Decompensation Severity

Virulence determinants and biofilm formation in clinical isolates of Enterococcus: A cross-sectional study

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Journal of Acute Disease 2020年第1期9卷 27-32页

作者： Fatemeh Shahi hajar Hamidi Saeed Khoshnood Golshan Mehdipour Aram Asarezadegan Dezfouli Ahmad Farajzadeh Sheikh Student Research Committee Ahvaz Jundishapur University of Medical SciencesAhvazIran Department of Microbiology Faculty of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran Infectious and Tropical Diseases Research Center Health Research InstituteAhvaz Jundishapur University of Medical SciencesAhvazIran Student Research Committee School of MedicineBam University of Medical SciencesBamIran

Objective:To evaluate the relationship between biofilm formation and incidence of virulence determinants in clinical isolates of ***:In this cross-sectional study,the clinical isolates of Enterococcus strains were collected from the university teaching hospitals in Ahvaz,Iran from June 2017 to June ***,the prevalence of Enterococcus species,antibiotic resistance,virulence factors,and biofilm-producing ability were ***:Of the 119 tested isolates,17(14.3%)were Enterococcus faecalis,72(60.5%)were Enterococcus faecium and 30(25.2%)were other Enterococcus *** was detected in 97(81.5%)isolates,enterococcal surface protein in 41(34.5%)isolates,serine protease in 39(32.8%)cases,accessory colonization factor in 111(93.3%)cases and pathogenicity islands in 17(14.3%)*** biofilm formation ability was observed in 75(63.0%)of all isolates and the association between the presence of enterococcal surface protein gene and biofilm formation was statistically *** resistance to vancomycin,gentamycin,and teicoplanin was indicated in Enterococcus faecium with 81.8%,58.4%,and 85.7%resistance rate,*** Enterococcus faecalis isolates were sensitive to teicoplanin and ***:The presence of antibiotic-resistance with several virulence factors in Enterococcus spp has become a *** prevalence of enterococcal surface protein gene among biofilm-producing isolates suggests a potential relation between biofilm formation and the enterococcal surface protein gene,and further studies are needed to identify the mechanism of biofilm inhibition.

关键词： Enterococcus spp Biofilm formation Antibioticresistance Virulence genes

The Relationships between Cognitive Neuropsychological State, Oxidative Stress and Genotoxicity in Radiology Staff

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Health 2014年第12期6卷 1376-1384页

作者： hajar Akbari Dastjerdi Mohammad Fazilati Ali Akbar Malekirad Habibollah Nazem Mohammad Abdollahi Akbar Zerratpisheh Department of Biology Payame Noor University Tehran Iran Faculty of Pharmacy and Pharmaceutical Sciences Research Center Tehran University of Medical Science (TUMS) Tehran Iran Islamic Azad University Jiroft Branch Jiroft Iran

Imbalance between the production and removal of reactive oxygen species (ROS) has been used for characterizing Oxidative stress. Extra amount of ROS are hazardous and can lead damages to the cells resulting in harsh diseases. For cancer, diabetes, psychological disorders and age-related disorders, latent of ROS in induction of alteration and DNA harm is a critical factor. Regarding these finding, the current research was planned to test the relationship between cognitive neuropsychological state and oxidative markers and genotoxicity in radiology staff. Total Number of 47 radiology staff, working in the radiology center of a referral University Hospital in Shiraz, were invited in the study. The participants were occupationally exposed to low-dose ionizing radiation (x-ray) for more than 2 years. Psychological disorder was analyzed by SCL-90-R. In the plasma, lipid peroxidation, DNA harm, catalase, superoxide dismutase, myeloperoxidase, and glutathione peroxidase activity were calculated. Associations between parameters were measured by using Pearson correlation coefficient and multivariate linear regression analyses. As a result, there was a positive considerable connection between catalase and paranoid ideation, Obsessive-Compulsive, Anxiety and total. Furthermore, the correlation between psychoticism, Interpersonal Sensitivity, Paranoid Ideation and DNA damage was positive. There were positive relationships between superoxide dismutase and psychomotor speed, initiative/energy, selective attention and verbal memory. So, there were significant relationships among interpersonal sensitivity, somatization, depression and gender. But, there were no major relationships among psychological distress, history workers and oxidative stress. In so many words, Oxidative stress and genotoxicity result in psychological disorders in radiology staff. So, radiology staff should have more attention, as they suffered from some psychological disorders.

关键词： Poisoning Ionizing Radiation Cognitive Neuropsychological Stress Oxidative Stress

Is coping strategies predictor of anxiety and depression in couple infertile?

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Health 2013年第3期5卷 643-649页

作者： Mahbobeh Faramarzi hajar Pasha Seddigheh Esmaelzadeh Gholamali Jorsarai Mohamad Reza Aghajani Mir Sharareh Abedi Fatemeh Zahra Infertility and Reproductive Health Research Center Babol University of Medical Sciences Babol Iran

Background: Infertility is a complex crisis of life and increases psychological difficulties such as anxiety and depression. Identification of copy strategies for stressful events like infertility is important. The aim of our study was to investigate the relationship between coping strategies with anxiety and depression symptoms in men and women’s infertile. Methods: This descriptive-analytic study was conducted from 2011-2012 on 168 Iranian infertile couples referred to the Fatemeh Zahra infertility and reproductive health research center of Babol university of medical science to initiate assistant reproductive technologies and completed the Ways of Coping Questionnaire (WCQ), The State-Trait Anxiety Inventory (STAI), and Beck Depression Inventory (BDI).The results were analyzed using t-test, the Pearson correlation and the stepwise model of multiple regression analysis. P Results: Escape/ avoidance contributed the greatest amount of unique variance to the model for anxiety/de-pression of infertile women (P < 0.0001, P < 0.001) and followed by distancing (P < 0.0001, P < 0.01), accepting responsibility(P < 0.0001, P < 0.01). Seeking social support was the negative significantly predictor for both anxiety and depression in infertile women (P < 0.01, P < 0.01), but planful problem solving was the inversely predictor for only depression in infertile women (P < 0.01). Escape/avoidance was the only predictor factor of the model anxiety for infertile men (P < 0.01). Escape/avoidance and self controlling were the positive predictor (P < 0.001) and planful problem solving was the negative predictor for men depression (P Conclusion: men and women infertile who use disproportionally maladaptive coping strategies such as escape/avoidance are predisposed to anxiety and depression symptoms. How using the coping strategies is very important in expressing anxiety and depression in infertile couples and training the adaptive coping strategies suggested by counseling centers.

关键词： Infertility Coping Depression Anxiety

Supplier Selection and Order Allocation a Main Factor in Supply Chain

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Supplier Selection and Order Allocation a Main Factor in Sup...

Managing the Mass Effect: A Rare Case of Giant Ethmoid Sinus Osteoma with Orbital Extension—A Case Report

2011 3rd International Conference on Advanced Management Science（ICAMS 2011）

作者： Kambiz Shahroudi hajar Rouydel Shamin Assimi Hamid Reza Eyvazi Assistant professor industrial management department Islamic Azad UniversityRasht BrunchRashtIran Young Researchers' club member Islamic Azad University-Rasht BrunchRashtIran Young Researchers' Club member Islamic Azad University-Rasht BranchRashtIran Master degree in business administration Islamic Azad University-Qazvin BranchQazvinIran

Supplier management is one of the most important parts in supply chain management that is increasingly recognized as a critical decision in the globalization *** of firms have been spending considerable amount of their revenues on *** supplier selection is one of the most important functions of purchasing *** aim of this research is to introduce an integrated model for supplier’s selection and order allocation in an automotive *** the research was performed in two sections and four *** first section in order to select the best suppliers we used an integrated AHPTOPSIS ***,after library studies and interview with experts,managers and specialists in supply chain management filed,decision criterion were identified through Delphi contains of main criteria and sub criteria for suppliers selection *** in the second section for order allocation to every selected suppliers in first section;we used a multi-objective linear programming *** objectives and subjective of suppliers and Automotive Company were identified in this *** show that applying a two phase AHP-TOPSIS methodology causes to select the best *** Automotive Company’s total costs will be minimized with using a MOLP model.

关键词： Supplier selection Analytical Hierarchy Process Supplier evaluation TOPSIS MOLP

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International Journal of Otolaryngology and Head & Neck Surgery 2023年第4期12卷 279-286页

作者： Siti hajar Noordiana Mohamed Hasshim Azuin Izzati Arshad Abdul Fattah Abdul Wahab Salina Husain Department of Otorhinolaryngology Universiti Kebangsaan Malaysia Kuala Lumpur Malaysia Department of Otorhinolaryngology Hospital Sungai Buloh Selangor Malaysia Department of Otorhinolaryngology Ara Damansara Medical Centre Selangor Malaysia

Background: Sinonasalosteomas are rare benign tumors that can cause clinical symptoms depending on their size and location. Osteomas are classified as giant osteomas when their size gets larger than three centimeters. In giant osteomas, severe symptoms and complications can occur if they expand into adjacent structures. Aim: In this case report, we highlight the diagnostic importance of CT scans of paranasal sinuses in diagnosing osteomas and the superiority of endoscopic surgery over an open approach in removing these benign tumors. Case Presentation: We report a rare case of giant ethmoidosteoma with extension to intraorbital facilities in 19 years old female which was causing a mass effect on the orbital space and discuss the appropriate management. Conclusion: Ethmoid sinus osteoma is asymptomatic until it increases in size producing a pressure effect on the eyes and sinusitis. CT imaging is the gold standard diagnostic modality. Surgical excision is the treatment of choice for ethmoid sinus osteoma. Due to the size of the lesion, endoscopic surgical excision is a less commonly employed modality, but it has advantages like earlier recovery and cosmetic benefits due to which it was the treatment employed in this case.

关键词： Giant Osteoma Ethmoid Sinus Paranasalosteoma Orbital Extension Case Report

Mandibular Embryonal Rhabdomyosarcoma Confused with a Vascular Malformation: About a Case

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Journal of Biosciences and Medicines 2023年第6期11卷 103-107页

作者： Massilia Bouhmidi hajar Boudarbala Ayad Ghannam Aziza Elouali Abdeladim Babakhouya Maria Rkain Noufissa Benajiba Mother-Child Hospital CHU Mohamed VI Oujda Morroco

Malignant mesenchymal tumors (MTM) in children represent 5% to 10% of malignant tumors in children. They constitute a heterogeneous group of tumors of various differentiations depending on their supposed tissue of origin. They mainly include tumors of muscular origin, those derived from connective, vascular, nervous, or adipose tissue. Rhabdomyosarcoma (RMS) is the most common mesenchymal tumor in children and adolescents (60% to 70% of them). And it accounts for 5.8% of all malignant solid tumors in children. Almost half of rhabdomyosarcomas occur in the head and neck. The prognosis for this type of tumor is particularly poor. A case of rhabdomyosarcoma in the mandible with extension to the abdominal wall and unilateral testis in a 6-month-old infant is reported with evolution since birth. It is a purplish lesion at the level under the right chin which was initially taken for vascular malformation, evolving very quickly towards a mandibular mass deforming the painful face with inflammatory signs, followed by the appearance of a hard swelling under the skin on the left flank taking on the same aspect of the mandibular mass. This observation illustrates the need to know how to systematically think about tumor causes in the face of atypical aspects and to carry out an anatomopathological examination.

关键词： Rhabdomyosarcoma Mandible Mesenchymal Tissue Vascular Malformation Abdominal Wall Testis